BRIC

2019

The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance

Agger, K., Nishimura, K., Miyagi, S., Messling, J-E., Rasmussen, K. D. & Helin, K., 3 Oct 2019, In: Blood. 134, 14, p. 1154-1158 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis

Backe, M. B., Jin, C., Andreone, L., Sankar, A., Agger, K., Helin, K., Madsen, A. N., Poulsen, S. S., Bysani, M., Bacos, K., Ling, C., Javier Perone, M., Holst, B. & Mandrup-Poulsen, T., 2019, In: Journal of Diabetes Research. 2019, 15 p., 5451038.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

15 Downloads (Pure)

The PCNA interaction motifs revisited: thinking outside the PIP-box

Prestel, A., Wichmann, N., Martins, J. M., Marabini, R., Kassem, N., Broendum, S. S., Otterlei, M., Nielsen, O., Willemoës, M., Ploug, M., Boomsma, W. & Kragelund, B. B., 1 Dec 2019, In: Cellular and Molecular Life Sciences. 76, 24, p. 4923-4943 21 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

The protein kinase CK2 contributes to the malignant phenotype of cholangiocarcinoma cells

Di Maira, G., Gentilini, A., Pastore, M., Caligiuri, A., Piombanti, B., Raggi, C., Rovida, E., Lewinska, M., Andersen, J. B., Borgo, C., Salvi, M., Ottaviani, D., Ruzzene, M. & Marra, F., 1 Nov 2019, In: Oncogenesis. 8, 11, p. 61-72 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

6 Downloads (Pure)

The splicing factor RBM25 controls MYC activity in acute myeloid leukemia

Ge, Y., Schuster, M. B., Pundhir, S., Rapin, N., Bagger, F. O., Sidiropoulos, N., Hashem, N. & Porse, B. T., 1 Dec 2019, In: Nature Communications. 10, 1, 14 p., 172.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

57 Downloads (Pure)

Tissue-Engineering the Intestine: The Trials before the Trials

Clevers, H., Conder, R. K., Li, V. S. W., Lutolf, M. P., Vallier, L., Chan, S., Grikscheit, T. C., Jensen, K. B. & De Coppi, P., 6 Jun 2019, In: Cell Stem Cell. 24, 6, p. 855-859 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Tracing the cellular dynamics of sebaceous gland development in normal and perturbed states

Andersen, M. S., Hannezo, E., Ulyanchenko, S., Estrach, S., Antoku, Y., Pisano, S., Boonekamp, K. E., Sendrup, S., Maimets, M., Pedersen, M. T., Johansen, J. V., Clement, D. L., Feral, C. C., Simons, B. D. & Jensen, K. B., 2019, In: Nature Cell Biology. 21, 8, p. 924-932 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Tracing the origin of adult intestinal stem cells

Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, S., Maimets, M., Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L. S., Larsen, A., Olesen, R. H., Andersen, C. Y., Thuesen, L. L., Hare, K. J., Pers, T. H., Khodosevich, K., Simons, B. D. & Jensen, K. B., 6 Jun 2019, In: Nature. 570, 7759, p. 107-111 5 p.

Research output: Contribution to journal › Letter › peer-review

38 Citations (Scopus)

Transcription Restart Establishes Chromatin Accessibility after DNA Replication

Stewart-Morgan, K. R., Reverón-Gómez, N. & Groth, A., 25 Jul 2019, In: Molecular Cell. 75, 2, p. 284-297 20 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Transforming growth factor-β activation in cell-free extracellular matrix preparations. Commentary

Couchman, J. R., 2019, In: Folia Histochemica et Cytobiologica.

Research output: Contribution to journal › Journal article › Communication

Uncovering the anatomical and molecular landscape of the starting point of Alzheimer’s disease in the brain

Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, E. S., Pihl, M., Thomsen, P. D., Hyttel, P., witter, M., Khodosevich, K., Gorodkin, J., Pers, T. H. & Hall, V. J., 2019.

Research output: Contribution to conference › Conference abstract for conference › Research

Whole genome sequencing of breast cancer

Rossing, M., Sørensen, C. S., Ejlertsen, B. & Nielsen, F. C., May 2019, In: APMIS - Journal of Pathology, Microbiology and Immunology. 127, 5, p. 303-315 13 p.

Research output: Contribution to journal › Review › peer-review

6 Citations (Scopus)

18 Downloads (Pure)

2018

Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2

Højfeldt, J. W., Laugesen, A., Willumsen, B. M., Damhofer, H., Hedehus, L., Tvardovskiy, A., Mohammad, F., Jensen, O. N. & Helin, K., 1 Mar 2018, In: Nature Structural & Molecular Biology. 25, p. 225-232 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

61 Citations (Scopus)

Accurate Recycling of Parental Histones Reproduces the Histone Modification Landscape during DNA Replication

Reverón-Gómez, N., González-Aguilera, C., Stewart-Morgan, K. R., Petryk, N., Flury, V., Graziano, S., Johansen, J. V., Jakobsen, J. S., Alabert, C. & Groth, A., 18 Oct 2018, In: Molecular Cell. 72, 2, p. 239-249 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

65 Citations (Scopus)

113 Downloads (Pure)

ADAM12-mediated shedding of basigin controls the subcellular localization and lactate transport of MCT4 and enhances collagen degradation in cancer cells: [Meeting Abstract}

Albrechtsen, R., Albrechtsen, N. J. W. & Kveiborg, M., 2018, In: International Journal of Experimental Pathology. 99, 6, p. A25-A25

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase

Kristensen, K. K., Midtgaard, S. R., Mysling, S., Kovrov, O., Hansen, L. B., Skar-Gislinge, N., Beigneux, A. P., Kragelund, B. B., Olivecrona, G., Young, S. G., Jørgensen, T. J. D., Fong, L. G. & Ploug, M., 26 Jun 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 26, p. E6020-E6029 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity

Bagger, S. O., Hopkinson, B. M., Pandey, D. P., Bak, M., Brydholm, A. V., Villadsen, R., Helin, K., Rønnov-Jessen, L., Petersen, O. W. & Kim, J., 2018, In: Molecular Cancer. 17, 1, p. 1-6 6 p., 171.

Research output: Contribution to journal › Comment/debate › Research › peer-review

7 Citations (Scopus)

63 Downloads (Pure)

An advanced enrichment method for rare somatic retroelement insertions sequencing

Komkov, A. Y., Minervina, A. A., Nugmanov, G. A., Saliutina, M. V., Khodosevich, K. V., Lebedev, Y. B. & Mamedov, I. Z., 2018, In: Mobile DNA. 9, 1, p. 1-11 11 p., 31.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

48 Downloads (Pure)

An enzyme-linked immunosorbent assay for measuring GPIHBP1 levels in human plasma or serum

Miyashita, K., Fukamachi, I., Nagao, M., Ishida, T., Kobayashi, J., Machida, T., Nakajima, K., Murakami, M., Ploug, M., Beigneux, A. P., Young, S. G. & Nakajima, K., Jan 2018, In: Journal of Clinical Lipidology. 12, 1, p. 203-210 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

A new class of genic nuclear RNA species in Arabidopsis

van Wonterghem, M., Thieffry, A., Boyd, M., Lange, J. B. & Brodersen, P., Feb 2018, In: FEBS Letters. 592, 4, p. 631-643 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines

Gonzalez, J. M., Baudet, A., Abelechian, S., Bonderup, K., d'Altri, T., Porse, B., Brakebusch, C., Juliusson, G. & Cammenga, J., Sept 2018, In: Genesis: The Journal of Genetics and Development (Print). 56, 9, p. 1-7 7 p., e23238.

Research output: Contribution to journal › Journal article › Research › peer-review

Animal arms

Häfner, S., Jan 2018, In: Microbes and Infection. 20, 1, p. 1-4 4 p.

Research output: Contribution to journal › Journal article › Communication

A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects

Draper, J. E., Sroczynska, P., Fadlullah, M. Z. H., Patel, R., Newton, G., Breitwieser, W., Kouskoff, V. & Lacaud, G., 2018, In: P L o S Genetics. 14, 1, p. 1-33 33 p., e1007127.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

54 Downloads (Pure)

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

Cancer Genome Atlas Research Network, 24 Oct 2018, In: Cell Systems. 7, 4, p. 422-437.e1-e7 23 p.

Research output: Contribution to journal › Journal article › Research › peer-review

43 Citations (Scopus)

214 Downloads (Pure)

Assessment Of The Correlation Between Dynamic Contrast Enhanced Computed Tomography And Histological And Vascular Biomarkers In Patients Resected For Colorectal Liver Metastases

Lauridsen, C., Axelsen, T., Hansen, M. L., Fallentin, E., Nielsen, M. B., Eefsen, R. L., Illemann, M., Engelholm, L., Vainer, B., Hoyer-hansen, G., Lund, I. K., Willemoe, G. L., Rolff, H. C., Mogensen, M. B. & Osterlind, K., 2018, In: Imaging in Medicine. 10, 6, p. 147-154

Research output: Contribution to journal › Journal article › Research › peer-review

21 Downloads (Pure)

BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma

Sime, W., Niu, Q., Abassi, Y., Masoumi, K. C., Zarrizi, R., Køhler, J. B., Kjellström, S., Lasorsa, V. A., Capasso, M., Fu, H. & Massoumi, R., 2018, In: Cell Death and Disease. 9, 5, p. 1-16 16 p., 458.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

40 Downloads (Pure)

Big browser is watching you

Häfner, S. J., 2018, In: Microbes and Infection. 20, 5, p. 271-274 4 p.

Research output: Contribution to journal › Editorial › peer-review

Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.

Kuhre, R. E., Albrechtsen, N. J. W., Larsen, O., Jepsen, S. L., Balk-Møller, E., Andersen, D. B., Deacon, C. F., Schoonjans, K., Reimann, F., Gribble, F. M., Albrechtsen, R., Hartmann, B., Rosenkilde, M. & Holst, J. J., 2018, In: Molecular Metabolism. 11, p. 84-95 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

60 Citations (Scopus)

60 Downloads (Pure)

Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity

Freiburghaus, C., Emruli, V. K., Johansson, A., Eskelund, C. W., Grønbæk, K., Olsson, R., Ek, F., Jerkeman, M. & Ek, S., 2018, In: BMC Cancer. 18, 1, 17 p., 466.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

43 Downloads (Pure)

Bowhead: Bayesian modelling of cell velocity during concerted cell migration

Engel, M., Longden, J., Ferkinghoff-Borg, J., Robin, X., Saginc, G. & Linding, R., Jan 2018, In: P L o S One. 14, 1, p. 1-10 10 p., e1005900.

Research output: Contribution to journal › Journal article › Research › peer-review

51 Downloads (Pure)

Cancer cells' ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential

Wullkopf, L., West, A. K. V., Leijnse, N., Cox, T. R., Madsen, C. D., Oddershede, L. B. & Erler, J. T., 2018, In: Molecular Biology of the Cell. 29, 20, p. 2378-2385 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

58 Citations (Scopus)

58 Downloads (Pure)

CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type

Kim, J., Stanescu, D. E. & Won, K. J., 30 Nov 2018, In: Nucleic Acids Research. 46, 21, p. 1-8 8 p., e124.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

48 Downloads (Pure)

Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M., & 7 othersJensen, K. B., Gögenur, I., Thielsen, P., Seidelin, J. B., Nielsen, O. H., Bjerrum, J. T. & Sandelin, A. G., 1 Dec 2018, In: Nature Communications. 9, 19 p., 1661.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

120 Downloads (Pure)

Clinical Impact of Clonal Hematopoiesis after Autologous Stem Cell Transplantation for Lymphoma: A National Population-Based Cohort Study

Husby, S., Francesco, F., Nielsen, C., Sorensen, B., Baech, J., Hansen, J. W., Gonzalez, G. G. R., Arboe, B., Andersen, L. P., Hastrup, E. K., Fischer-Nielsen, A., Saekmose, S. G., Hansen, P. B., Christiansen, I., Clasen-Linde, E., Knudsen, L. M., Grell, K., Segel, E. K., Ebbesen, L. H., Thorsgaard, M., & 6 othersJosefsson, P. L., El-Galaly, T. C., Brown, P. D. N., Weisenfeldt, J., Larsen, T. S. & Gronbaek, K., 2018, In: Blood. 132, Suppl 1, p. 607 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research

Correction: p190 RhoGAP promotes contact inhibition in epithelial cells by repressing YAP activity

Frank, S. R., Köllmann, C. P., Luong, P., Galli, G. G., Zou, L., Bernards, A., Getz, G., Calogero, R. A., Frödin, M. & Hansen, S. H., 2018, In: The Journal of Cell Biology. 217, 9, p. 3313 1 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

36 Downloads (Pure)

COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis

Li, Y., Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, L. B., Seidelin, J. B., Jensen, K. B. & Nielsen, O. H., Oct 2018, In: EBioMedicine. 36, p. 497-507

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

43 Downloads (Pure)

Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

Laviña, B., Castro, M., Niaudet, C., Cruys, B., Álvarez-Aznar, A., Carmeliet, P., Bentley, K., Brakebusch, C., Betsholtz, C. & Gaengel, K., 2 Jul 2018, In: Development (Cambridge, England). 145, 13, 20 p., dev161182.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

Defective TAFI activation in hemophilia a mice is a major contributor to joint bleeding

Wyseure, T., Cooke, E. J., Declerck, P. J., Behrendt, N., Meijers, J. C. M., Von Drygalski, A. & Mosnier, L. O., 2018, In: Blood. 132, 15, p. 1593-1603 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

30 Downloads (Pure)

De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium

Lavrsen, K., Dabelsteen, S., Vakhrushev, S. Y., Levann, A. M. R., Haue, A. D., Dylander, A., Mandel, U., Hansen, L., Frödin, M., Bennett, E. P. & Wandall, H. H., 26 Jan 2018, In: The Journal of Biological Chemistry. 293, p. 1298-1314

Research output: Contribution to journal › Journal article › Research › peer-review

32 Citations (Scopus)

Desmoplastic Tumor Microenvironment and Immunotherapy in Cholangiocarcinoma

Høgdall, D., Lewinska, M. & Andersen, J. B., Mar 2018, In: Trends in Cancer. 4, 3, p. 239-255 17 p.

Research output: Contribution to journal › Review › peer-review

33 Citations (Scopus)

Dietary Control of Skin Lipid Composition and Microbiome

Moestrup, K. S., Chen, Y., Schepeler, T., Schweiger, P. J. & Jensen, K. B., May 2018, In: The Journal of Investigative Dermatology. 138, 5, p. 1225-1228 4 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

3 Citations (Scopus)

Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment

Lauridsen, F. KB., Jensen, T. L., Rapin, N., Aslan, D., Wilhelmson, A. S., Pundhir, S., Rehn, M., Paul, F., Giladi, A., Hasemann, M. S., Serup, P., Amit, I. & Porse, B. T., 17 Jul 2018, In: Cell Reports. 24, 3, p. 766-780 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

83 Downloads (Pure)

Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression

Erice, O., Labiano, I., Arbelaiz, A., Santos-Laso, A., Munoz-Garrido, P., Jimenez-Agüero, R., Olaizola, P., Caro-Maldonado, A., Martín-Martín, N., Carracedo, A., Lozano, E., Marin, J. J., O'Rourke, C. J., Andersen, J. B., Llop, J., Gómez-Vallejo, V., Padro, D., Martin, A., Marzioni, M., Adorini, L., & 4 othersTrauner, M., Bujanda, L., Perugorria, M. J. & Banales, J. M., Apr 2018, In: B B A - Reviews on Cancer. 1864, 4, Part B, p. 1335-1344

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

Distinct CED-10/Rac1 domains confer context-specific functions in development

Nørgaard, S., Deng, S., Cao, W. & Pocock, R., 2018, In: P L o S Genetics. 14, 9, p. 1-24 24 p., e1007670.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

45 Downloads (Pure)

DNA methylation levels of the ELMO gene promoter CpG islands in human glioblastomas

Michaelsen, S. R., Aslan, D., Urup, T., Poulsen, H. S., Grønbæk, K., Broholm, H. & Kristensen, L. S., 2018, In: International Journal of Molecular Sciences . 19, 3, 13 p., 679.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

40 Downloads (Pure)

DNMT1 regulates expression of MHC class I in post-mitotic neurons

Gustafsson, J. R., Katsioudi, G., Degn, M., Ejlerskov, P., Issazadeh-Navikas, S. & Kornum, B. R., 2018, In: Molecular Brain. 11, 1, p. 1-16 16 p., 36.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

62 Downloads (Pure)

Drug Target Commons 2.0: a community platform for systematic analysis of drug-target interaction profiles

Tanoli, Z. R., Alam, Z., Vähä-Koskela, M., Ravikumar, B., Malyutina, A., Jaiswal, A., Tang, J., Wennerberg, K. & Aittokallio, T., 2018, In: Database: The Journal of Biological Databases and Curation. 2018, 2018, p. 1-13 13 p., bay083.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

62 Downloads (Pure)

Dual inhibition of DNMTs and EZH2 can overcome both intrinsic and acquired resistance of myeloma cells to IMiDs in a cereblon-independent manner

Dimopoulos, K., Søgaard Helbo, A., Fibiger Munch-Petersen, H., Sjö, L., Christensen, J., Sommer Kristensen, L., Asmar, F., Hermansen, N. E. U., O'Connel, C., Gimsing, P., Liang, G. & Grønbaek, K., 1 Feb 2018, In: Molecular Oncology. 12, 2, p. 180-195

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

59 Downloads (Pure)

eIF5A is required for autophagy by mediating ATG3 translation

Lubas, M., Harder, L. M., Kumsta, C., Tiessen, I., Hansen, M., Andersen, J. S., Lund, A. H. & Frankel, L., Jun 2018, In: EMBO Reports. 19, 6, p. 1-17 17 p., e46072.

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

EIF5A mediates autophagy via translation of ATG3

Frankel, L. B., 2018, In: Autophagy. 14, 7, p. 1288-1289 2 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

2 Citations (Scopus)

Research output

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