Research output per year
Research output per year
Personal profile
CV
Education
1998 Ph.D., Molecular Biology, University of Copenhagen
1994 M.Sc., Molecular Biology, University of Copenhagen
Career
2007- Associate Professor, BRIC and Copenhagen University Hospital
2003-2007 Group leader, Copenhagen University Hospital
2001-2003 Senior Researcher, Copenhagen University Hospital
1999-2001 Postdoc, Copenhagen University Hospital
1998-1999 Postdoc, University of Copenhagen
Primary fields of research
HematopoiesisMouse genetics
Cancer
Current research
C/EBPalpha in normal and malignant hematopoiesisHematopoetic and leukemic stem cells
Nonsense-mediated mRNA in mammalian development
Fields of interest
HematopoiesisMouse genetics
Cancer
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis
Morgan, M., Kabayama, Y., Much, C., Ivanova, I., Di Giacomo, M., Auchynnikava, T., Monahan, J. M., Vitsios, D. M., Vasiliauskaitė, L., Comazzetto, S., Rappsilber, J., Allshire, R. C., Porse, B. T., Enright, A. J. & O'Carroll, D., 1 Mar 2019, In: Cell Research.Research output: Contribution to journal › Journal article › Research › peer-review
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ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination
Søndergaard, E., Rauch, A., Michaut, M., Rapin, N., Rehn, M., Wilhelmson, A. S., Camponeschi, A., Hasemann, M. S., Bagger, F. O., Jendholm, J., Knudsen, K. J., Mandrup, S., Mårtensson, I. L. & Porse, B. T., 26 Nov 2019, In: Cell Reports. 29, 9, p. 2756-2769.e6 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterozygous loss of Srp72 in mice is not associated with major hematological phenotypes
D'Altri, T., Schuster, M. B., Wenzel, A. & Porse, B. T., 1 Oct 2019, In: European Journal of Haematology. 103, 4, p. 319-328 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response
Johnson, J. L., Stoica, L., Liu, Y., Zhu, P. J., Bhattacharya, A., Buffington, S., Huq, R., Eissa, N. T., Larsson, O., Porse, B. T., Domingo, D., Nawaz, U., Carroll, R., Jolly, L., Scerri, T. S., Kim, H.-G., Brignell, A., Coleman, M. J., Braden, R. & Kini, U. & 11 others, , 20 Nov 2019, In: Neuron.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML
Jakobsen, J. S., Laursen, L. G., Schuster, M. B., Pundhir, S., Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mönch, K., Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. & Porse, B. T., 2019, In: Science Advances. 5, 7, p. 1-16 17 p., eaaw4304.Research output: Contribution to journal › Journal article › Research › peer-review
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The splicing factor RBM25 controls MYC activity in acute myeloid leukemia
Ge, Y., Schuster, M. B., Pundhir, S., Rapin, N., Bagger, F. O., Sidiropoulos, N., Hashem, N. & Porse, B. T., 1 Dec 2019, In: Nature Communications. 10, 1, 14 p., 172.Research output: Contribution to journal › Journal article › Research › peer-review
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A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines
Gonzalez, J. M., Baudet, A., Abelechian, S., Bonderup, K., d'Altri, T., Porse, B., Brakebusch, C., Juliusson, G. & Cammenga, J., Sept 2018, In: Genesis: The Journal of Genetics and Development (Print). 56, 9, p. 1-7 7 p., e23238.Research output: Contribution to journal › Journal article › Research › peer-review
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Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment
Lauridsen, F. K., Jensen, T. L., Rapin, N., Aslan, D., Wilhelmson, A. S., Pundhir, S., Rehn, M., Paul, F., Giladi, A., Hasemann, M. S., Serup, P., Amit, I. & Porse, B. T., 17 Jul 2018, In: Cell Reports. 24, 3, p. 766-780 15 p.Research output: Contribution to journal › Journal article › Research › peer-review