Research output per year
Research output per year
Personal profile
Short presentation
Kim Jensen received his PhD in molecular biology from the University of Aarhus in 2003. Here Kim had developed an improved method for the analysis of the cell surface composition based on recombinant antibody technology. In 2003 he joined Professor Fiona Watt’s group at the London Research Institute, Cancer Research UK, as a post-doctoral fellow. Based on cutting edge technologies and analysis of mouse models he went on to identified Lrig1, a negative regulator of receptor tyrosine kinases, as a novel marker of both human and mouse epidermal stem cells. In 2010 Kim received a Wellcome Trust Career Development Fellowship to establish his own group at the University of Cambridge. Here Kim’s group has focused on the role of adult stem cells in tissue homeostasis. Kim was in 2012 awarded a Lundbeck Foundation Fellowship, and his group is now continuing their research on adult stem cells at BRIC.
Primary fields of research
- Stem cells and their role in tissue homeostasis
- Tissue development and stem cell specification
- The role of adult stem cells in disease
- Stem cells and cancer
CV
Career
2013-
Group leader, Biotech Research & Innovation Centre, University of Copenhagen
2010-
Group leader, University of Cambridge, UK
2007-2010
Senior Research Associate in the lab of Prof Fiona Watt, University of Cambridge, UK
2003-2007
Research fellow in lab of Prof Fiona Watt, London Research Institute, CRUK,
Education
MSc BIoteknology and Molecular Biology, University of Aarhus, Denmark
PhD, Molecular Biology, University of Aarhus, Denmark
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy
Bergenheim, F., Seidelin, J. B., Pedersen, M. T., Mead, B. E., Jensen, K. B., Karp, J. M. & Nielsen, O. H., 27 May 2019, In: Stem Cell Research & Therapy. 10, 1, p. 1-12 12 p., 148.Research output: Contribution to journal › Journal article › Research › peer-review
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IL-17R–EGFR axis links wound healing to tumorigenesis in Lrig1 + stem cells
Chen, X., Cai, G., Liu, C., Zhao, J., Gu, C., Wu, L., Hamilton, T. A., Zhang, C. J., Ko, J., Zhu, L., Qin, J., Vidimos, A., Koyfman, S., Gastman, B. R., Jensen, K. B. & Li, X., 1 Jan 2019, In: Journal of Experimental Medicine. 216, 1, p. 195-214 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Managing vitamin D deficiency in inflammatory bowel disease
Nielsen, O. H., Hansen, T. I., Gubatan, J. M., Jensen, K. B. & Rejnmark, L., 1 Oct 2019, In: Frontline Gastroenterology. p. 1-7Research output: Contribution to journal › Review › peer-review
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Tissue-Engineering the Intestine: The Trials before the Trials
Clevers, H., Conder, R. K., Li, V. S. W., Lutolf, M. P., Vallier, L., Chan, S., Grikscheit, T. C., Jensen, K. B. & De Coppi, P., 6 Jun 2019, In: Cell Stem Cell. 24, 6, p. 855-859 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tracing the cellular dynamics of sebaceous gland development in normal and perturbed states
Andersen, M. S., Hannezo, E., Ulyanchenko, S., Estrach, S., Antoku, Y., Pisano, S., Boonekamp, K. E., Sendrup, S., Maimets, M., Pedersen, M. T., Johansen, J. V., Clement, D. L., Feral, C. C., Simons, B. D. & Jensen, K. B., 2019, In: Nature Cell Biology. 21, 8, p. 924-932 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tracing the origin of adult intestinal stem cells
Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, S., Maimets, M., Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L. S., Larsen, A., Olesen, R. H., Andersen, C. Y., Thuesen, L. L., Hare, K. J., Pers, T. H., Khodosevich, K., Simons, B. D. & Jensen, K. B., 6 Jun 2019, In: Nature. 570, 7759, p. 107-111 5 p.Research output: Contribution to journal › Letter › peer-review
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Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M., & 7 others, 1 Dec 2018, In: Nature Communications. 9, 19 p., 1661.Research output: Contribution to journal › Journal article › Research › peer-review
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COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis
Li, Y., Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, L. B., Seidelin, J. B., Jensen, K. B. & Nielsen, O. H., Oct 2018, In: EBioMedicine. 36, p. 497-507Research output: Contribution to journal › Journal article › Research › peer-review
Datasets
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A semi-automated intestinal organoid screening method demonstrates epigenetic control of epithelial maturation
Ostrop, J. (Creator), Zwiggelaar, R. (Contributor), Terndrup Pedersen, M. (Contributor), Gerbe, F. (Contributor), Korbinian, B. (Contributor), Lindholm, H. T. (Contributor), Díez-Sánchez, A. (Contributor), Parmar, N. (Contributor), Radetzki, S. (Contributor), von Kries, J. P. (Contributor), Jay, P. (Contributor), Jensen, K. B. (Contributor), Arrowsmith, C. (Contributor) & Oudhoff, M. J. (Contributor), University of Dundee, 2020
DOI: 10.17867/10000145, https://idr.openmicroscopy.org/webclient/?show=screen-2451
Dataset