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Nicolai Jacob Wewer Albrechtsen

Medical Doctor, PhD, GCSRT

20132019

Research activity per year

Personal profile

CV

EDUCATION

2014 (may)-2015 (june): Global Clinical Scholar at Harvard University, Cambridge, Massachusetts, USA. Invited member of the Harvard Alumni. 

2011-2014: Master of Medicine at the Faculty of Health and Medical Sciences, University of Copenhagen.

2012-2013: Research Year Graduate, Holst Group

2008-2011: Bachelor in Medicine at the Faculty of Health and Medical Sciences, University of Copenhagen

 

CLINICAL EXPERIENCE

2018 – Resident at Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark.

2018: B-license qualified

2017-2018: Junior Resident, Department of Orthopedic Surgery, Emergency Room, Trauma Medicine, Herlev Hospital, Denmark & general practitioner (Laura Lundby) (in Danish called klinisk basisk uddannelse)

 

ACADEMIC EXPERIENCE

2019 – present: Assistant Professor of Clinical Proteomics and Metabolism, Center for Protein Research, SUND, KU

2017 - 2019: Postdoc at Clinical Proteomic, Center for Protein Research, SUND, KU

2017 - Present: Affiliated Researcher & Primary co-supervisor for several students (2019: Five students) at the Holst Laboratory, BMI, SUND, KU

January 2014 – present: Affiliated Researcher at the Max Planck Institute for Biochemistry, Munich, Germany

January 2014 – dec 2016:

PhD thesis: Measurement of Gastrointestinal Hormones under supervision of Prof. Jens J. Holst, Assoc. prof. Bolette Hartmann, Assoc. prof. Carolyn F. Deacon and Prof. Matthias Mann. Department of Biomedical Sciences & NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, DK & Department of Proteomics and Signal Transduction at Max Planck Institute for Biochemistry, Munich, DE.

September 2011 – December 2013: Research Fellow at Holst Laboratory at the Faculty of Health and Medical Sciences, the Department of Biomedical Science

January 2013: Internship at the Max Planck Institute of Biochemistry in Munch – Scientific Director, Professor Matthias Mann. Topic: Clinical Proteomics

August 2012: Internship the Kansas University Medical Center, USA – Professor Ivan Damjanov. Topic: Pathology/Biochemistry. 

 

Professional Experiences

2008 - 2011: Consultant, Microsoft Danmark A/S. Two main project: "The Guru Program" and launch of Windows 7

Awards/Other

2019: Boserup Price

2017: Elected overseas member of the Royal Society of Medicine (by invitation of Prof. Sir Steven Bloom, Imperial College London)

2016: Talent price from the Lundbeck Foundation

2015: Eliteforsk Fellowship

2015: Invited member of the Harvard Alumni & Harvard Medical School Alumni by Associate Dean, Global Education MBBS, FRCP (UK), MBA Ajay K. Singh, ([email protected])

2014:EMBO fellowship award

2014: Albert Renold Fellowship (EFSD) from the European Foundation for the Study of Diabetes

2014: EMBO fellowship award

2014: Krogsgaard mindelegat (KU)

 

 

Primary fields of research

I have devoted my life to understanding the physiology of our gut, liver and pancreas with a clinical orientation towards new insight in metabolic diseases and stratified medicine. During my first three years academia, I contributed to novel measurements techniques of proteins and peptides in human and rodents e.g. the development of an ELISA for glucagon commercialized by Mercodia. This assay is now the most used for glucagon biology and has recently also implemented at Hospitals in Denmark for diagnosis of neuroendocrine tumors (glucagonomas).

 

During my PhD I worked closely with Matthias Mann on developing Plasma Proteomic Profiling which I have used in a series of humans’ studies with several contributions such as identification of a new glucagon-like peptide, an inflammatory panel with potential prognostic value, and finally identification of a potential new enzyme degrading several peptide hormones including the incretins. State-of the art analytical chemistry (mass-spectrometry based proteomics) has therefore been my cornerstone and have generated several seminal international collaborations each with potential clinical impact such as elaboration and application of an appetite regulatory peptide hormone together with Steven Bloom (Imperial College of London, UK) and identified new signaling path of insulin in adipocytes with Ronald Kahn (Joslin Diabetes Center, Boston, USA) with proteomics.

Teaching

SUPERVISING AND MENTORING

Mentor for medical students appointed by the Municipality of Copenhagen and primary co-supervisor for nine pre/postgraduate students: Lærke Ørsted Svensson, Kristine Wurtz Poulsen, Katrine Douglas, Marie Winther-Sørensen, Lina Janah, Elena Stojanovska, Sasha Kjeldsen, Juliana Josephine Vivian Grandt and Haidar Wardah. In addition, co-supervisor of several (>5) master, PhD students and postdocs.

INTERNATIONAL RELATED TEACHING

Instructor of MOOC Diabetes – a Global Challenge (launched February 2014) and Diabetes – Essential Facts (launched December 2016) with more than 100.000 current and former participants: https://www.coursera.org/course/diabetes

NATIONAL RELATED TEACHING

Gastrointestinal Physiology (5th semester medical students) since 2011 ~ 50 hours excluding preparation

Energy expenditure and biochemistry (5th semester medical students) since 2013 ~ 60 hours excluding preparation

Human physiology (1st semester medical students) since 2014 ~ 120 hours excluding preparation

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

External positions

University of Copenhagen

1 May 2018 → …

Keywords

  • Faculty of Health and Medical Sciences

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