Research output per year
Research output per year
Personal profile
Short presentation
Computational genomicist with strong interests in transcription and transcriptional regulation.
The Andersson lab focuses on genomics and computational/statistical modelling of transcriptional regulation based on large-scale sequencing data. Our main aims are to characterize and better understand the architectures of transcriptional regulation and the fundamental properties of enhancers and promoters.
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Collaborations and top research areas from the last five years
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Determinants of enhancer and promoter activities of regulatory elements
Andersson, R. & Sandelin, A., 1 Feb 2020, In: Nature Reviews Genetics. 17 p.Research output: Contribution to journal › Review › peer-review
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CAGEfightR: analysis of 5'-end data using R/Bioconductor
Thodberg, M., Thieffry, A., Vitting-Seerup, K., Andersson, R. & Sandelin, A., 4 Oct 2019, In: BMC Bioinformatics. 20, 13 p., 487.Research output: Contribution to journal › Journal article › Research › peer-review
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PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells
Agrawal-Singh, S., Lerdrup, M., Gomes, A.-L. R., van de Werken, H. J. G., Johansen, J. V., Andersson, R., Sandelin, A., Helin, K. & Hansen, K., 23 Jan 2019, In: eLife. 8, p. 1-32 32 p., e40364.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P.J.-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T. & Petersen, A. M. & 7 others, , 1 Dec 2018, In: Nature Communications. 9, 19 p., 1661.Research output: Contribution to journal › Journal article › Research › peer-review
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Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes
Grarup, N., Moltke, I., Andersen, M. K., Dalby, M., Vitting-Seerup, K., Kern, T. S., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., Gilly, A., Suveges, D., Dedoussis, G., Zeggini, E., Pedersen, O. B., Andersson, R., Bjerregaard, P., Jørgensen, M. E., Albrechtsen, A. & Hansen, T., 2018, In: Nature Genetics. 50, 2, p. 172-174 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MCM2 promotes symmetric inheritance of modified histones during DNA replication
Petryk, N., Dalby, M., Wenger, A., Stromme, C. B., Strandsby, A., Andersson, R. & Groth, A., 28 Sept 2018, In: Science. 361, 6409, p. 1389-1392 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease
Baillie, J. K., Bretherick, A., Haley, C. S., Clohisey, S., Gray, A., Neyton, L. P. A., Barrett, J., Stahl, E. A., Tenesa, A., Andersson, R., Brown, J. B., Faulkner, G. J., Lizio, M., Schaefer, U., Daub, C., Itoh, M., Kondo, N., Lassmann, T., Kawai, J. & Mole, D. & 14 others, , Mar 2018, In: PLoS Computational Biology. 14, 3, 24 p., e1005934.Research output: Contribution to journal › Journal article › Research › peer-review
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The RNA exosome contributes to gene expression regulation during stem cell differentiation
Llinares, M. L., Karadoulama, E., Chen, Y., Wojenski, L. A., Villafano, G. J., Bornholdt, J., Andersson, R., Core, L., Sandelin, A. & Jensen, T. H., 30 Nov 2018, In: Nucleic Acids Research. 46, 21, p. 11502-11513Research output: Contribution to journal › Journal article › Research › peer-review
Datasets
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Transcription factor expression is the main determinant of variability in gene co-activity
van Duin, L. (Creator), Krautz, R. (Creator), Rennie, S. (Creator) & Andersson, R. (Creator), Zenodo, 2022
DOI: 10.5281/zenodo.7180322, https://zenodo.org/records/7180322
Dataset
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FANTOM5 transcribed enhancers in mm10
Dalby, M. (Creator), Rennie, S. (Creator) & Andersson, R. (Creator), Zenodo, 2018
DOI: 10.5281/zenodo.1411211, https://zenodo.org/record/1411211
Dataset