Research output per year
Research output per year
Personal profile
Short presentation
Jesper B Andersen received his Ph.D. in molecular and cellular biology from the University of Aarhus. His doctoral dissertation described the role of two interferon-stimulated genes, i.e., ISG15 and RNase-L in cancer, and was conducted under the joint mentorship of Dr. Bret A. Hassel, University of Maryland Baltimore, Marlene & Stewart Greenebaum Cancer Center in Baltimore USA and Dr. Just Justesen at the University of Aarhus, Denmark. Dr. Andersen joined the laboratory of Dr. Snorri S Thorgeirsson (Laboratory of Experimental Carcinogenesis) at the National Cancer Institute (NCI), NIH in Bethesda USA in 2007 as a Research Fellow where his research has involved several genomic and epigenomic aspects of hepatocarcinogenesis. At the NCI, Jesper focused his research on the systematic characterization of cholangiocarcinoma (CCA), a lethal and treatment refractory subtype of liver cancer of the biliary tree. Using cutting-edge translational genomics, e.g., single-cell genomics, he is studying tumor heterogeneity. In 2014, Jesper was appointed Group leader at BRIC.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Keywords
- BRIC
- Tumor heterogeneity
- Genomic-driven therapy
- Translational genomics
- Single cell genomics
- Epigenomic-driven therapy
- Integrative (cross-species) - omics
- Hepatobiliary cancer
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Collaborations and top research areas from the last five years
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Identification of a pan-gamma-secretase inhibitor response signature for notch-driven cholangiocarcinoma
O'Rourke, C. J., Matter, M. S., Nepal, C., Caetano-Oliveira, R., Ton, P. T., Factor, V. M. & Andersen, J. B., 1 Jan 2020, In: Hepatology.Research output: Contribution to journal › Journal article › Research › peer-review
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A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation
Thestrup, M. I., Caviglia, S., Cayuso, J., Heyne, R. L. S., Ahmad, R., Hofmeister, W., Satriano, L., Wilkinson, D. G., Andersen, J. B. & Ober, E. A., 1 Dec 2019, In: Nature Communications. 10, 1, 14 p., 5220.Research output: Contribution to journal › Journal article › Research › peer-review
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Application of patient-derived liver cancer cells for phenotypic characterization and therapeutic target identification
Castven, D., Becker, D., Czauderna, C., Wilhelm, D., Andersen, J. B., Strand, S., Hartmann, M., Heilmann-Heimbach, S., Roth, W., Hartmann, N., Straub, B. K., Mahn, F. L., Franck, S., Pereira, S., Haupts, A., Vogel, A., Wörns, M. A., Weinmann, A., Heinrich, S. & Lang, H. & 3 others, , 1 Jun 2019, In: International Journal of Cancer. 144, 11, p. 2782-2794 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Causes of hOCT1-dependent cholangiocarcinoma resistance to sorafenib and sensitization by tumor-selective gene therapy
Lozano, E., Macias, R. I. R., Monte, M. J., Asensio, M., Del Carmen, S., Sanchez-Vicente, L., Alonso-Peña, M., Al-Abdulla, R., Munoz-Garrido, P., Satriano, L., O'Rourke, C. J., Banales, J. M., Avila, M. A., Martinez-Chantar, M. L., Andersen, J. B., Briz, O. & Marin, J. J. G., 1 Oct 2019, In: Hepatology. 70, 4, p. 1246-1261 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cholangiocarcinoma: State-of-the-art knowledge and challenges
Banales, J. M., Cardinale, V., Macias, R. I. R., Andersen, J. B., Braconi, C., Carpino, G., Alvaro, D. & Calvisi, D. F., May 2019, In: Liver International. 39, S1, p. 5-6 2 p.Research output: Contribution to journal › Editorial › peer-review
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Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib
Al-Abdulla, R., Lozano, E., Macias, R. I. R., Monte, M. J., Briz, O., O'Rourke, C. J., Serrano, M. A., Banales, J. M., Avila, M. A., Martinez-Chantar, M. L., Geier, A., Andersen, J. B. & Marin, J. J. G., Mar 2019, In: British Journal of Pharmacology. 176, 6, p. 787-800 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Epigenome Remodeling in Cholangiocarcinoma
O'Rourke, C. J., Lafuente-Barquero, J. & Andersen, J. B., Jun 2019, In: Trends in Cancer. 5, 6, p. 335-350 16 p.Research output: Contribution to journal › Review › peer-review
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Metabolic rearrangements in primary liver cancers: cause and consequences
Satriano, L., Lewinska, M., Rodrigues, P. M., Banales, J. M. & Andersen, J. B., 1 Dec 2019, In: Nature Reviews. Gastroenterology & Hepatology. 16, 12, p. 748-766 17 p.Research output: Contribution to journal › Review › peer-review
Activities
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NAFLD
Andersen, J. B. (Invited speaker)
24 Nov 2017Activity: Talk or presentation types › Lecture and oral contribution
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ILCA: Molecular classification and key drivers of intrahepatic CCA
Andersen, J. B. (Invited speaker)
Sept 2017Activity: Talk or presentation types › Lecture and oral contribution
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Chair: Liver cancer session
Andersen, J. B. (Panel member)
Sept 2017Activity: Talk or presentation types › Lecture and oral contribution
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Riccardo Cortese memorial lecture
Andersen, J. B. (Invited speaker)
Jul 2017Activity: Talk or presentation types › Lecture and oral contribution
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Korean liver week
Andersen, J. B. (Invited speaker)
Jun 2017Activity: Talk or presentation types › Lecture and oral contribution
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BioPeople: Future of Oncology Biomarkers Seminar & Biomed
Andersen, J. B. (Panel member)
May 2017Activity: Talk or presentation types › Lecture and oral contribution
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University of Mainz, Medicine 1: Liver lunch
Andersen, J. B. (Invited speaker)
28 Mar 2017Activity: Talk or presentation types › Lecture and oral contribution
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Satorius Research Xchange Forum: Insights, Translation and Solutions
Andersen, J. B. (Invited speaker)
21 Feb 2017 → 23 Feb 2017Activity: Talk or presentation types › Lecture and oral contribution
Prizes
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Danish Cancer Society: Research Scholarship
Andersen, J. B. (Recipient), 2002
Prize: Prizes, scholarships, distinctions
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American Federation for Aging Research (AFAR): Junior Investigator Award
Andersen, J. B. (Recipient), 2007
Prize: Prizes, scholarships, distinctions
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International Society for Interferon and Cytokine Research (ISICR): Young Investigator Award
Andersen, J. B. (Recipient), 2007
Prize: Prizes, scholarships, distinctions
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European Association for the Study of the Liver (EASL). Young Investigator Award
Andersen, J. B. (Recipient), 2008
Prize: Prizes, scholarships, distinctions
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Danish Medical Research Council (DFF): Sundhed og Sygdom
Andersen, J. B. (Recipient), 2008
Prize: Prizes, scholarships, distinctions
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International Liver Cancer Association (ILCA): Investigator Award
Andersen, J. B. (Recipient), 2010
Prize: Prizes, scholarships, distinctions
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Danish Cancer Society "Knæk Cancer": Talented Young Investigator
Andersen, J. B. (Recipient), 2014
Prize: Prizes, scholarships, distinctions
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NNF: Hallas-Møller Fellowship
Andersen, J. B. (Recipient), 2015
Prize: Prizes, scholarships, distinctions