Research output per year
Research output per year
Personal profile
Short presentation
We aim to further our understanding of the genome by integrating large-scale genomic datasets. We also develop computational methods to exploit multi-dimensional genomic/epigenomic landscapes to understand cell-type specific or spatio-temporal gene regulation. Using computational integrative approaches, we also study transcriptional mechanisms controlling cell differentiation and cell identify. Our area of research include studying gene regulations in adipocyte, liver, cancer cells and stem cell differentiation.
https://www.bric.ku.dk/Research/won-group/
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Research Assistant Professor, University of Pennsylvania Perelman School of Medicine
1 Jan 2011 → 30 May 2018
UC, San Diego
1 Jan 2007 → 31 Dec 2010
Bioinformatics Centre, Department of Biology and Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen (Stud.)
1 Jan 2006 → 31 Dec 2006
Univ Southampton, Southampton SO17 1BJ, Hants, England
1 Feb 2003 → 31 Dec 2005
Hanoi University of Science and Technology
1 Aug 1999 → 31 Dec 2001
Chung-Ang University
1 Mar 1998 → 31 Dec 1999
Chung-Ang University
1 Mar 1992 → 31 Dec 1995
1 Apr 2018 → …
External positions
University of Pennsylvania
1 Jun 2018 → 30 Jun 2021
Keywords
- BRIC
- Computational biology
- Machine Learning
- Bioinformatics
- Faculty of Health and Medical Sciences
Fingerprint
Dive into the research topics where Kyoung Jae Won is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Genomic architecture of Shh-dependent cochlear morphogenesis
Muthu, V., Rohacek, A. M., Yao, Y., Rakowiecki, S. M., Brown, A. S., Zhao, Y-T., Meyers, J., Won, K-J., Ramdas, S., Brown, C. D., Peterson, K. A. & Epstein, D. J., 19 Sept 2019, In: Development (Cambridge, England). 146, 18, 12 p., 181339.Research output: Contribution to journal › Journal article › Research › peer-review
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CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type
Kim, J., Stanescu, D. E. & Won, K. J., 30 Nov 2018, In: Nucleic Acids Research. 46, 21, p. 1-8 8 p., e124.Research output: Contribution to journal › Journal article › Research › peer-review
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Defiant: (DMRs: easy, fast, identification and ANnoTation) identifies differentially Methylated regions from iron-deficient rat hippocampus
Condon, D. E., Tran, P. V., Lien, Y-C., Schug, J., Georgieff, M. K., Simmons, R. A. & Won, K-J., 5 Feb 2018, In: BMC Bioinformatics. 19, 1, p. 31Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue
Hill, D. A., Lim, H-W., Kim, Y. H., Ho, W. Y., Foong, Y. H., Nelson, V. L., Nguyen, H. C. B., Chegireddy, K., Kim, J., Habertheuer, A., Vallabhajosyula, P., Kambayashi, T., Won, K-J. & Lazar, M. A., 29 May 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 22, p. E5096-E5105Research output: Contribution to journal › Journal article › Research › peer-review
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PKCα-LSD1-NF-κB-Signaling Cascade Is Crucial for Epigenetic Control of the Inflammatory Response
Kim, D., Nam, H. J., Lee, W., Yim, H. Y., Ahn, J-Y., Park, S. W., Shin, H-J. R., Yu, R., Won, K-J., Bae, J-S., Kim, K. I. & Baek, S. H., 1 Feb 2018, In: Molecular Cell. 69, 3, p. 398-411.e6Research output: Contribution to journal › Journal article › Research › peer-review
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Rev-erbα dynamically modulates chromatin looping to control circadian gene transcription
Kim, Y. H., Marhon, S. A., Zhang, Y., Steger, D. J., Won, K-J. & Lazar, M. A., 16 Mar 2018, In: Science (New York, N.Y.). 359, 6381, p. 1274-1277 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Shared nucleotide flanks confer transcriptional competency to bZip core motifs
Cohen, D. M., Lim, H-W., Won, K-J. & Steger, D. J., 19 Sept 2018, In: Nucleic Acids Research. 46, 16, p. 8371-8384Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptomic Analysis Reveals Novel Mechanisms Mediating Islet Dysfunction in the Intrauterine Growth-Restricted Rat
Rashid, C. S., Lien, Y-C., Bansal, A., Jaeckle-Santos, L. J., Li, C., Won, K-J. & Simmons, R. A., 1 Feb 2018, In: Endocrinology. 159, 2, p. 1035-1049 15 p.Research output: Contribution to journal › Journal article › Research › peer-review