Lukasz Krych

2019

Bacterial species to be considered in quality assurance of mice and rats

Hansen, A. K., Nielsen, D. S., Krych, L. & Hansen, C. H. F., 1 Jun 2019, In: Laboratory Animals. 53, 3, p. 281-291

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Cesarean section increases sensitivity to oxazolone-induced colitis in C57BL/6 mice

Zachariassen, L. F., Hansen, A. K., Krych, L., Nielsen, D. S., Holm, T. L., Tougaard, P. & Hansen, C. H. F., 2019, In: Mucosal Immunology. 12, 6, p. 1348-1357 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Cesarean Section Induces Microbiota-Regulated Immune Disturbances in C57BL/6 Mice

Zachariassen, L. F., Krych, L., Rasmussen, S. H., Nielsen, D. S., Kot, W., Holm, T. L., Hansen, A. K. & Hansen, C. H. F., 1 Jan 2019, In: Journal of Immunology. 202, 1, p. 142-150

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Development of the equine gut microbiota

Lindenberg, F., Krych, L., Kot, W., Fielden, J., Frøkiær, H., van Galen, G., Nielsen, D. S. & Hansen, A. K., 1 Dec 2019, In: Scientific Reports. 9, 1, 9 p., 14427.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

29 Downloads (Pure)

DNA enrichment and tagmentation method for species-level identification and strain-level differentiation using ON-rep-seq

Krych, L., Castro-Mejía, J. L., Forero-Junco, L. M., Moesby, D. N., Mikkelsen, M. B., Rasmussen, M. A., Sykulski, M. & Nielsen, D. S., 1 Dec 2019, In: Communications Biology. 2, 10 p., 369.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

9 Downloads (Pure)

Effect of potato fiber on survival of Lactobacillus species at simulated gastric conditions and composition of the gut microbiota in vitro

Larsen, N., de Souza, C. B., Krych, L., Kot, W., Leser, T. D., Sørensen, O. B., Blennow, A., Venema, K. & Jespersen, L., 2019, In: Food Research International. 125, 9 p., 108644.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Expression of immune regulatory genes correlate with the abundance of specific Clostridiales and Verrucomicrobia species in the equine ileum and cecum

Lindenberg, F., Krych, L., Fielden, J., Kot, W., Frøkiær, H., van Galen, G., Nielsen, D. S. & Hansen, A. K., 2019, In: Scientific Reports. 9, 1, 10 p., 12674.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

18 Downloads (Pure)

Impact of Early Exposure to Cefuroxime on the Composition of the Gut Microbiota in Infants Following Cesarean Delivery

Kamal, S. S., Hyldig, N., Krych, L., Greisen, G., Krogfelt, K. A., Zachariassen, G. & Nielsen, D. S., Jul 2019, In: Journal of Pediatrics. 210, p. 99-105, e1-e2

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Linking cocoa varietals and microbial diversity of Nicaraguan fine cocoa bean fermentations and their impact on final cocoa quality appreciation

Papalexandratou, Z., Kaasik, K., Kauffmann, L. V., Skorstengaard, A., Bouillon, G., Espensen, J. L., Hansen, L. H., Jakobsen, R. R., Blennow, A., Krych, L., Castro-Mejía, J. L. & Nielsen, D. S., 2 Sept 2019, In: International Journal of Food Microbiology. 304, p. 106-118

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Oral LPS Dosing Induces Local Immunological Changes in the Pancreatic Lymph Nodes in Mice

Kihl, P., Krych, L., Deng, L., Kildemoes, A. O., Laigaard, A., Hansen, L. H., Hansen, C. H. F., Buschard, K., Nielsen, D. S. & Hansen, A. K., 2019, In: Journal of Diabetes Research. 2019, 9 p., 1649279.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

36 Downloads (Pure)

Potential of Pectins to Beneficially Modulate the Gut Microbiota Depends on Their Structural Properties

Larsen, N., de Souza, C. B., Krych, L., Cahú, T. B., Wiese, M., Kot, W., Hansen, K. M., Blennow, A., Venema, K. & Jespersen, L., 2019, In: Frontiers in Microbiology. 10, p. 1-13 223.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

64 Downloads (Pure)

Prebiotic Effect of Lycopene and Dark Chocolate on Gut Microbiome with Systemic Changes in Liver Metabolism, Skeletal Muscles and Skin in Moderately Obese Persons

Wiese, M., Bashmakov, Y., Chalyk, N., Nielsen, D. S., Krych, L., Kot, W., Klochkov, V., Pristensky, D., Bandaletova, T., Chernyshova, M., Kyle, N. & Petyaev, I., 2019, In: BioMed Research International. 2019, 15 p., 4625279.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

15 Downloads (Pure)

Preterm Birth Has Effects on Gut Colonization in Piglets Within the First 4 Weeks of Life

Kamal, S. S., Andersen, A. D., Krych, L., Lauridsen, C., Sangild, P. T., Thymann, T. & Nielsen, D. S., 1 May 2019, In: Journal of Pediatric Gastroenterology and Nutrition. 68, 5, p. 727-733 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Prevotella abundance predicts weight loss success in healthy, overweight adults consuming a whole-grain diet ad libitum: A post hoc analysis of a 6-wk randomized controlled trial

Christensen, L., Vuholm, S., Roager, H. M., Nielsen, D. S., Krych, L., Kristensen, M. B., Astrup, A. & Hjorth, M. F., 1 Dec 2019, In: Journal of Nutrition. 149, 12, p. 2174-2181 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Targeting gut microbiota and barrier function with prebiotics to alleviate autoimmune manifestations in NOD mice

Hansen, C. H. F., Larsen, C. S., Petersson, H. O., Zachariassen, L. F., Vegge, A., Lauridsen, C., Kot, W., Krych, L., Nielsen, D. S. & Hansen, A. K., 1 Sept 2019, In: Diabetologia. 62, 9, p. 1689-1700

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

TL1A Aggravates Cytokine-Induced Acute Gut Inflammation and Potentiates Infiltration of Intraepithelial Natural Killer Cells in Mice

Tougaard, P., Martinsen, L. O., Zachariassen, L. F., Krych, L., Nielsen, D. S., Buus, T. B., Pedersen, A. E., Hansen, A. K., Skov, S. & Hansen, C. H. F., 21 Feb 2019, In: Inflammatory Bowel Diseases. 25, 3, p. 510-523

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

2018

Changes in Gut Microbiota Prior to Influenza A Virus Infection Do Not Affect Immune Responses in Pups or Juvenile Mice

Fuglsang, E., Pizzolla, A., Krych, L., Nielsen, D. S., Brooks, A. G., Frokiaer, H. & Reading, P. C., 12 Sept 2018, In: Frontiers in Cellular and Infection Microbiology. 8, 16 p., 319.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Cheese brines from Danish dairies reveal a complex microbiota comprising several halotolerant bacteria and yeasts

Haastrup, M. K., Johansen, P., Malskær, A. H., Castro-Mejía, J. L., Kot, W., Krych, L., Arneborg, N. & Jespersen, L., 2018, In: International Journal of Food Microbiology. 285, p. 173-187 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Colonization of Cutibacterium avidum during infant gut microbiota establishment

Rocha Martin, V. N., Schwab, C., Krych, L., Voney, E., Geirnaert, A., Braegger, C. & Lacroix, C., 18 Nov 2018, In: FEMS Microbiology Ecology. 95, 1, p. 1-14 fiy215.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Effect of the dietary polyacetylenes falcarinol and falcarindiol on the gut microbiota composition in a rat model of colorectal cancer

Kobaek-Larsen, M., Nielsen, D. S., Kot, W., Krych, L., Christensen, L. P. & Baatrup, G., 2018, In: BMC Research Notes. 11, p. 1-6 411.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

45 Downloads (Pure)

Exploring the microbiota from cheese brines at Danish dairies by culture dependent and independent techniques

Johansen, P., Malskær, A. H., Haastrup, M. K., Castro Mejia, J. L., Kot, W., Krych, L., Arneborg, N. & Arneborg, N., 2018.

Research output: Contribution to conference › Poster › Research › peer-review

Gut microbiota recovery and immune response in ampicillin-treated mice

Castro Mejia, J. L., Jakesevic, M., Fabricius, N. F., Krych, L., Nielsen, D. S., Kot, W., Bendtsen, K. M. B., Vogensen, F. K., Hansen, C. H. F. & Hansen, A. K., Jun 2018, In: Research in Veterinary Science. 118, p. 357-364 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Have you tried spermine? A rapid and cost-effective method to eliminate dextran sodium sulfate inhibition of PCR and RT-PCR

Krych, L., Kot, W., Bendtsen, K. M. B., Hansen, A. K., Vogensen, F. K. & Nielsen, D. S., Jan 2018, In: Journal of Microbiological Methods. 144, p. 1-7 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

33 Citations (Scopus)

Influenza A Virus Infection Alters Gut Microbiota Composition in Juvenile Mice

Fuglsang, E., Krych, L., Nielsen, D. S., Frøkiær, H. & Reading, P. C., 2018, In: Journal of Infectious Diseases & Travel Medicine. 2, 3, 10 p., 000118.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Downloads (Pure)

Lacto-fermented sauerkraut improves symptoms in IBS patients independent of product pasteurisation - a pilot study

Nielsen, E. S., Garnås, E., Jensen, K. J., Hansen, L. H., Olsen, P. S., Ritz, C., Krych, L. & Nielsen, D. S., Oct 2018, In: Food & Function. 9, 10, p. 5323-5335 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics

Rune, I., Rolin, B., Lykkesfeldt, J., Nielsen, D. S., Krych, Ł., Kanter, J. E., Bornfeldt, K. E., Kihl, P., Buschard, K., Josefsen, K., Fels, J. J., Mortensen, A., Christoffersen, B., Kirk, R. K. & Hansen, A. K., 2018, In: Scientific Reports. 8, 1, 12 p., 5416.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

59 Downloads (Pure)

Oral insulin does not alter gut microbiota composition of NOD mice

Kihl, P., Krych, L., Buschard, K., Wesley, J. D., Kot, W., Hansen, A. K., Nielsen, D. S. & von Herrath, M. G., 2018, In: Diabetes/Metabolism Research and Reviews. 34, 6, 9 p., e3010.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Postnatal Administration of Lactobacillus rhamnosus HN001 Ameliorates Perinatal Broad-Spectrum Antibiotic-Induced Reduction in Myelopoiesis and T Cell Activation in Mouse Pups

Fuglsang, E., Krych, L., Lundsager, M. T., Nielsen, D. S. & Frøkiær, H., Nov 2018, In: Molecular Nutrition and Food Research. 62, 22, p. 1-12 1800510.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Understanding the prebiotic potential of different dietary fibers using an in vitro continuous adult fermentation model (PolyFermS)

Poeker, S. A., Geirnaert, A., Berchtold, L., Greppi, A., Krych, L., Steinert, R. E., de Wouters, T. & Lacroix, C., 1 Dec 2018, In: Scientific Reports. 8, 12 p., 4318 .

Research output: Contribution to journal › Journal article › Research › peer-review

61 Citations (Scopus)

146 Downloads (Pure)

2017

A high-throughput qPCR system for simultaneous quantitative detection of dairy Lactococcus lactis and Leuconostoc bacteriophages

Muhammed, M. K., Krych, L., Nielsen, D. S. & Vogensen, F. K., 2017, In: PLOS ONE. 12, 3, 12 p., e0174223.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

94 Downloads (Pure)

A polyphenol-enriched diet and Ascaris suum infection modulate mucosal immune responses and gut microbiota composition in pigs

Williams, A. R., Krych, L., Fauzan Ahmad, H., Nejsum, P., Skovgaard, K., Nielsen, D. S. & Thamsborg, S. M., Oct 2017, In: PLOS ONE. 12, 10, 21 p., e0186546.

Research output: Contribution to journal › Journal article › Research › peer-review

27 Citations (Scopus)

90 Downloads (Pure)

Dietary cinnamaldehyde enhances acquisition of specific antibodies following helminth infection in pigs

Williams, A. R., Hansen, T. V. A., Krych, L., Bin Ahmad, H. F., Nielsen, D. S., Skovgaard, K. & Thamsborg, S. M., Jul 2017, In: Veterinary Immunology and Immunopathology. 189, p. 43-52 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

Effect of early-life gut mucosal compromise on disease progression in NOD mice

Bendtsen, K. M., Hansen, C. H., Krych, L., Buschard, K., Farlov, H. & Hansen, A. K., 2017, In: Comparative Medicine. 67, 5, p. 388-399 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Immunological effects of reduced mucosal integrity in the early life of BALB/c mice

Bendtsen, K. M. B., Hansen, C. H. F., Krych, L., Skovgaard, K., Kot, W. P., Vogensen, F. K. & Hansen, A. K., May 2017, In: PLOS ONE. 12, 5, 20 p., 0176662.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

151 Downloads (Pure)

Metagenomic analysis of dairy bacteriophages: extraction method and pilot study on whey samples derived from using undefined and defined mesophilic starter cultures

Muhammed, M. K., Kot, W. P., Neve, H., Mahony, J., Castro Mejia, J. L., Krych, L., Hansen, L. H., Nielsen, D. S., Sørensen, S. J., Heller, K. J., van Sinderen, D. & Vogensen, F. K., 2017, In: Applied and Environmental Microbiology. 83, 19, 15 p., e00888-17.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Sensitivity to oxazolone induced dermatitis is transferable with gut microbiota in mice

Fisker, L., Krych, L., Engkilde, K., Nielsen, D. S., Kot, W. P., Hansen, C. H. F. & Hansen, A. K., 2017, In: Scientific Reports. 7, 11 p., 44385.

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

117 Downloads (Pure)

Whole-grain rye and wheat affect some markers of gut health without altering the fecal microbiota in healthy overweight adults: A 6-week randomized trial

Vuholm, S., Nielsen, D. S., Iversen, K. N., Suhr, J., Westermann, P., Krych, L., Andersen, J. R. & Kristensen, M., 1 Nov 2017, In: Journal of Nutrition. 147, 11, p. 2067-2075 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

2016

Fermentation of African kale (Brassica carinata) using L. plantarum BFE 5092 and L. fermentum BFE 6620 starter strains

Oguntoyinbo, F. A., Cho, G.-S., Trierweiler, B., Kabisch, J., Rösch, N., Neve, H., Bockelmann, W., Frommherz, L., Nielsen, D. S., Krych, L. & Franz, C. M. A. P., 5 Dec 2016, In: International Journal of Food Microbiology. 238, p. 103-112 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Minimal short-term effect of dietary 2'-fucosyllactose on bacterial colonisation, intestinal function and necrotising enterocolitis in preterm pigs

Cilieborg, M. S., Bering, S. B., Østergaard, M. V., Jensen, M. L., Krych, L., Newburg, D. S. & Sangild, P. T., 14 Sept 2016, In: British Journal of Nutrition. 116, 5, p. 834-841 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Treatment with a monoclonal anti-IL-12p40 antibody induces substantial gut microbiota changes in an experimental colitis model

Castro Mejia, J. L., Jakesevic, M., Krych, L., Nielsen, D. S., Hansen, L. H., Sondergaard, B. C., Kvist, P. H., Hansen, A. K. & Holm, T. L., 2016, In: Gastroenterology Research and Practice. 2016, 12 p., 4953120.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

430 Downloads (Pure)

2015

A review of applied aspects of dealing with gut microbiota impact on rodent models

Hansen, A. K., Krych, L., Nielsen, D. S. & Hansen, C. H. F., 31 Aug 2015, In: ILAR Journal. 56, 2, p. 250-64 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

Colonic lesions, cytokine profiles, and gut microbiota in plasminogen-deficient mice

Vestergaard, B., Krych, L., Lund, L. R., Jørgensen, B. M. P., Hansen, L. H., Jensen, H. E., Nielsen, D. S. & Hansen, A. K., Oct 2015, In: Comparative Medicine. 65, 5, p. 382-397 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs

Shen, R. L., Thymann, T., Østergaard, M. V., Støy, A. C. F., Krych, L., Nielsen, D. S., Lauridsen, C., Hartmann, B., Holst, J. J., Burrin, D. G. & Sangild, P. T., 4 Sept 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 309, 5, p. G310-G323 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

54 Citations (Scopus)

Gut microbial markers are associated with diabetes onset, regulatory imbalance, and IFN-γ level in NOD mice

Krych, L., Nielsen, D. S., Hansen, A. K. & Hansen, C. H. F., 3 Feb 2015, In: Gut Microbes. 6, 2, p. 101-109 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

70 Citations (Scopus)

Introducing enteral feeding induces intestinal subclinical inflammation and respective chromatin changes in preterm pigs

Willems, R., Krych, L., Rybicki, V., Jiang, P., Sangild, P. T., Shen, R. L., Hensel, K. O., Wirth, S., Postberg, J. & Jenke, A. C., 1 Jun 2015, In: Epigenomics. 7, 4, p. 553-565 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

165 Downloads (Pure)

Investigating the long-term effect of subchronic phencyclidine-treatment on novel object recognition and the association between the gut microbiota and behavior in the animal model of schizophrenia

Jørgensen, B. M. P., Krych, L., Brønnum Pedersen, T., Plath, N., Redrobe, J. P., Hansen, A. K., Nielsen, D. S., Spang Pedersen, C., Larsen, C. S. & Sørensen, D. B., 5 Mar 2015, In: Physiology & Behavior. 141, p. 32-39 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

39 Citations (Scopus)

Phytase-producing capacity of yeasts isolated from traditional African fermented food products and PHYPk gene expression of Pichia kudriavzevii strains

Greppi, A., Krych, L., Costantini, A., Rantsiou, K., Hounhouigan, D. J., Arneborg, N., Cocolin, L. & Jespersen, L., 6 Jul 2015, In: International Journal of Food Microbiology. 205, p. 81-89 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

The effect of Lactobacillus paracasei subsp. paracasei L. casei W8® on blood levels of triacylglycerol is independent of colonisation

Bjerg, A. T., Sørensen, M. B., Krych, L., Hansen, L. H., Astrup, A., Kristensen, M. B. & Nielsen, D. S., 2015, In: Beneficial Microbes. 6, 3, p. 263-269 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

TL1A regulates TCRγδ⁺ intraepithelial lymphocytes and gut microbial composition

Tougaard, P., Skov, S., Pedersen, A. E., Krych, L., Nielsen, D. S., Bahl, M. I., Christensen, E. G., Licht, T. R., Poulsen, S. S., Metzdorff, S. B., Hansen, A. K. & Hansen, C. H. F., 1 Mar 2015, In: European Journal of Immunology. 45, 3, p. 865-875 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

2014

A maternal gluten-free diet reduces inflammation and diabetes incidence in the offspring of NOD mice

Hansen, C. H. F., Krych, L., Buschard, K., Metzdorff, S. B., Nellemann, C. L., Hansen, L. H., Nielsen, D. S., Frøkiær, H., Skov, S. & Hansen, A. K., Aug 2014, In: Diabetes. 63, 8, p. 2821-2832 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

73 Citations (Scopus)

Lukasz Krych

Research output

Search results