Jørgen Olsen

2019

Upregulation of PD-1 follows tumour development in the AOM/DSS model of inflammation-induced colorectal cancer in mice

Yassin, M., Sadowska, Z., Djurhuus, D., Nielsen, B., Tougaard, P., Olsen, J. & Pedersen, A. E., 2019, In: Immunology. 158, 1, p. 35-46 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

2018

Rectal insulin instillation inhibits inflammation and tumor development in chemically-induced colitis

Yassin, M., Sadowska, Z., Tritsaris, K., Kissow, H., Hansen, C. H. F., Forman, J. L., Rogler, G., Troelsen, J. T., Pedersen, A. E. & Olsen, J., 1 Dec 2018, In: Journal of Crohn's and Colitis. 12, 12, p. 1459–1474 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

2017

Turning Microscopy in the Medical Curriculum Digital: Experiences from The Faculty of Health and Medical Sciences at University of Copenhagen

Vainer, B., Mortensen, N. W., Poulsen, S. S., Sørensen, A. H., Olsen, J., Saxild, H. H. & Johansen, F. F., 2017, In: Journal of Pathology Informatics. 8, 10 p., 11.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

74 Downloads (Pure)

2016

CDX2 downregulation is associated with poor differentiation and MMR deficiency in colon cancer

Olsen, J., Eiholm, S., Kirkeby, L. T., Espersen, M. L. M., Jess, P., Gögenür, I., Olsen, J. & Troelsen, J. T., 1 Feb 2016, In: Experimental and Molecular Pathology. 100, 1, p. 59-66 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

2015

High interleukin-6 mRNA expression is a predictor of relapse in colon cancer

Olsen, J., Kirkeby, L. T., Olsen, J., Eiholm, S., Jess, P., Gögenur, I. & Troelsen, J. T., 1 Apr 2015, In: Anticancer Research. 35, 4, p. 2235-40 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Integrative Transcriptomic and Metabonomic Molecular Profiling of Colonic Mucosal Biopsies Indicates a Unique Molecular Phenotype for Ulcerative Colitis

Rantalainen, M., Bjerrum, J. T., Olsen, J., Nielsen, O. H. & Wang, Y., 2 Jan 2015, In: Journal of Proteome Research. 14, 1, p. 479-90 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

2014

Assessment of the validity of a multigene analysis in the diagnostics of inflammatory bowel disease

Bjerrum, J. T., Nyberg, C., Olsen, J. & Nielsen, O. H., May 2014, In: Journal of Internal Medicine. 275, 5, p. 484-93 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2

Boyd, M., Coskun, M., Lilje, B., Andersson, R., Hoof, I., Lange, J. B., Dahlgaard, K., Olsen, J., Vitezic, M., Bjerrum, J. T., Seidelin, J. B., Nielsen, O. H., Troelsen, J. & Sandelin, A. G., 1 Dec 2014, In: D N A Research. 21, 6, p. 569-583 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

1750 Downloads (Pure)

Integration of transcriptomics and metabonomics: improving diagnostics, biomarker identification and phenotyping in ulcerative colitis

Bjerrum, J. T., Rantalainen, M., Wang, Y., Olsen, J. & Nielsen, O. H., Apr 2014, In: Metabolomics. 10, 2, p. 280-290 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Transcriptional analysis of left-sided colitis, pancolitis, and ulcerative colitis-associated dysplasia

Bjerrum, J. T., Nielsen, O. H., Riis, L. B., Pittet, V., Mueller, C., Rogler, G. & Olsen, J., 1 Dec 2014, In: Inflammatory Bowel Diseases. 20, 12, p. 2340-2352 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

2013

Early changes in gene expression induced by blue light irradiation of A2E-laden retinal pigment epithelial cells

van der Burght, B. W., Hansen, M., Olsen, J., Zhou, J., Wu, Y., Nissen, M. H. & Sparrow, J. R., Nov 2013, In: Acta Ophthalmologica (Online). 91, 7, p. e537-e545

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

miR-20b, miR-98, miR-125b-1, and let-7e as new potential diagnostic biomarkers in ulcerative colitis

Coskun, M., Bjerrum, J. T., Seidelin, J. B., Troelsen, J., Olsen, J. & Nielsen, O. H., 21 Jul 2013, In: World Journal of Gastroenterology. 19, 27, p. 4289-99 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

59 Citations (Scopus)

Regulation of APC and AXIN2 expression by intestinal tumor suppressor CDX2 in colon cancer cells

Olsen, A. K., Coskun, M., Bzorek, M., Kristensen, M. H., Danielsen, E. T., Jørgensen, S., Olsen, J., Engel, U., Holck, S. & Troelsen, J., Jun 2013, In: Carcinogenesis. 34, 6, p. 1361-9 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

2012

A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin

Egerod, K. L., Engelstoft, M. S., Grunddal, K. V., Nøhr, M. K., Secher, A., Sakata, I., Pedersen, J., Windeløv, J. A., Füchtbauer, E-M., Olsen, J., Sundler, F., Christensen, J. P., Wierup, N., Olsen, J. V., Holst, J. J., Zigman, J. M., Poulsen, S. S. & Schwartz, T. W., 1 Dec 2012, In: Endocrinology. 153, 12, p. 5782-95 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

210 Citations (Scopus)

Consumption of probiotics increases the effect of regulatory T cells in transfer colitis

Petersen, E. R., Claesson, M. H., Schmidt, E. G. W., Jensen, S. S., Ravn, P., Olsen, J., Ouwehand, A. C. & Kristensen, N. N., Jan 2012, In: Inflammatory Bowel Diseases. 18, 1, p. 131-142 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

Fejlformidlet dannelse

Olsen, J., 4 Oct 2012, In: Dagbladet Information.

Research output: Contribution to journal › Contribution to newspaper - Comment/debate

Gene expression profiles in stages II and III colon cancers: application of a 128-gene signature

Thorsteinsson, M., Kirkeby, L. T., Hansen, R., Lund, L. R., Sørensen, L. T., Gerds, T. A., Jess, P. & Olsen, J., Dec 2012, In: International Journal of Colorectal Disease.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

pcaGoPromoter--an R package for biological and regulatory interpretation of principal components in genome-wide gene expression data

Hansen, M., Gerds, T. A., Nielsen, O. H., Seidelin, J. B., Troelsen, J. T. & Olsen, J., 27 Feb 2012, In: P L o S One. 7, 2, p. e32394

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Peer review er ikke vejen

Olsen, J., 31 Jan 2012, In: Dagbladet Information.

Research output: Contribution to journal › Comment/debate › Communication

TNF-a-induced down-regulation of CDX2 suppresses MEP1A expression in colitis

Coskun, M., Olsen, A. K., Holm, T. L., Kvist, P. H., Nielsen, O. H., Riis, L. B., Olsen, J. & Troelsen, J. T., Jun 2012, In: BBA General Subjects. 1822, 6, p. 843-51 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

2011

Impaired hapten sensitization in patients with autoimmune disease

Bangsgaard, N., Engkilde, K., Menné, T., Løvendorf, M., Jacobsen, G. K., Olsen, J. & Skov, L., Sept 2011, In: Clinical and Experimental Immunology. 165, 3, p. 310-7 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

MAP kinases in inflammatory bowel disease

Coskun, M., Olsen, J., Seidelin, J. B. & Nielsen, O. H., 18 Mar 2011, In: Clinica Chimica Acta. 412, 7-8, p. 513-20 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

101 Citations (Scopus)

Matrix metalloproteinase-8 overexpression prevents proper tissue repair

Danielsen, P. L., Holst, A. V., Maltesen, H. R., Bassi, M. R., Holst, P. J., Heinemeier, K. M., Olsen, J., Danielsen, C. C., Poulsen, S. S., Jorgensen, L. N. & Agren, M. S., Nov 2011, In: Surgery. 150, 5, p. 897-906 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

The -14010*C variant associated with lactase persistence is located between an Oct-1 and HNF1a binding site and increases lactase promoter activity

Jensen, T. G. K., Liebert, A., Lewinsky, R., Swallow, D. M., Olsen, J. & Troelsen, J. T., 1 Oct 2011, In: Human Genetics. 130, 4, p. 483-93 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

2010

Control of intestinal promoter activity of the cellular migratory regulator gene ELMO3 by CDX2 and SP1

Coskun, M., Boyd, M., Olsen, J. & Troelsen, J. T., 15 Apr 2010, In: Journal of Cellular Biochemistry. 109, 6, p. 1118-28 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

Genome-wide analysis of CDX2 binding in intestinal epithelial cells (Caco-2)

Boyd, M., Hansen, M., Jensen, T. G. K., Perearnau, A., Olsen, A. K., Bram, L. L., Bak, M., Tommerup, N., Olsen, J. & Troelsen, J. T., 13 Aug 2010, In: Journal of Biological Chemistry. 285, 33, p. 25115-25 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

54 Citations (Scopus)

Genome-wide Gene Expression Analysis of Mucosal Colonic Biopsies and Isolated Colonocytes Suggests a Continuous Inflammatory State in the Lamina Propria of Patients with Quiescent Ulcerative Colitis

Bjerrum, J. T., Hansen, M., Olsen, J., Nielsen, O. H., Bjerrum, J. T., Hansen, M., Olsen, J. & Nielsen, O. H., 2010, In: Inflammatory Bowel Diseases. 16, 6, p. 999-1007 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

Identification of a functional hepatocyte nuclear factor 4 binding site in the neutral ceramidase promoter

Maltesen, H. R., Troelsen, J. T. & Olsen, J., 1 Dec 2010, In: Journal of Cellular Biochemistry. 111, 5, p. 1330-6 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Metabonomics in Ulcerative Colitis: Diagnostics, Biomarker Identification, And Insight into the Pathophysiology

Bjerrum, J. T., Nielsen, O. H., Hao, F., Tang, H., Nicholson, J. K., Wang, Y., Olsen, J., Bjerrum, J. T., Nielsen, O. H., Shen, H., Tang, H. R., Nicholson, J. B., Wang, L. & Olsen, J., 5 Feb 2010, In: Journal of Proteome Research. 9, 2, p. 954-962 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

118 Citations (Scopus)

MicroRNAs and potential target interactions in psoriasis

Zibert, J. R., Løvendorf, M. B., Litman, T., Olsen, J., Kaczkowski, B. & Skov, L., Jun 2010, In: Journal of Dermatological Science. 58, 3, p. 177-185 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

149 Citations (Scopus)

2 Downloads (Pure)

2009

Betydningen af mikroribonukleinsyre for sygdomsudvikling

Translated title of the contribution: The role of micro-ribonucleic acid in disease developmentWidjaya, B., Seidelin, J. B., Olsen, J. & Nielsen, O. H., 16 Nov 2009, In: Ugeskrift for Laeger. 171, 47, p. 3441-4 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Diagnosis of ulcerative colitis before onset of inflammation by multivariate modeling of genome-wide gene expression data

Olsen, J., Gerds, T. A., Seidelin, J. B., Csillag, C., Bjerrum, J. T., Troelsen, J. T. & Nielsen, O. H., 2009, In: Inflammatory Bowel Diseases. 15, 7, p. 1032-8 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

71 Citations (Scopus)

Evidence for impaired CARD15 signalling in Crohn's disease without disease linked variants

Seidelin, J. B., Broom, O. J., Olsen, J. & Nielsen, O. H., 2009, In: PLoS ONE. 4, 11, p. e7794

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Influence of smoking on colonic gene expression profile in Crohn's disease

Nielsen, O. H., Bjerrum, J. T., Csillag, C., Nielsen, F. C. & Olsen, J., 2009, In: PLoS ONE. 4, 7, p. e6210

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Mapping of HNF4alpha target genes in intestinal epithelial cells

Boyd, M., Bressendorff, S., Moller, J., Olsen, J. & Troelsen, J., 2009, In: BMC Gastroenterology. 9, 1, p. 68

Research output: Contribution to journal › Journal article › Research › peer-review

53 Citations (Scopus)

Mitogen activated protein kinases: a role in inflammatory bowel disease?

Broom, O. J., Widjaya, B., Troelsen, J., Olsen, J. & Nielsen, O. H., 2009, In: Clinical and Experimental Immunology. 158, 3, p. 272-80 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

119 Citations (Scopus)

Optimization of RNA preservation in granulation tissue in the expanded polytetrafluoroethylene (ePTFE) tube model

Danielsen, P. L., Koudahl, V., Christensen, B. & Olsen, J., 2009, In: Preparative Biochemistry and Biotechnology. 39, 4, p. 413-8 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

2008

Cellular cross talk in the small intestinal mucosa: postnatal lymphocytic immigration elicits a specific epithelial transcriptional response

Schjoldager, K. T-B. G., Maltesen, H. R., Balmer, S., Lund, L. R., Claesson, M. H., Sjöström, H., Troelsen, J. T. & Olsen, J., 2008, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 294, 6, p. G1335-43

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Genome-wide expression profiling during protection from colitis by regulatory T cells.

Kristensen, N. N., Olsen, J., Gad, M. & Claesson, M. H., 2008, In: Inflammatory Bowel Diseases. 14, 1, p. 75-87 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications.

Bjerrum, J. T., Nielsen, O. H., Wang, Y. L. & Olsen, J., 2008, In: Nature Clinical Practice Gastroenterology & Hepatology. 5, 6, p. 332-43 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

2007

An increased expression of cysteinyl leukotriene 2 receptor in colorectal adenocarcinomas correlates with high differentiation

Magnusson, C., Ehrnstrom, R., Olsen, J. & Sjølander, A., 2007, In: Cancer Research. 67, 19, p. 9190-9198 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

37 Citations (Scopus)

CARD15 status and familial predisposition for Crohn's disease and colonic gene expression

Csillag, C., Nielsen, O. H., Borup, R., Olsen, J., Bjerrum, J. T. & Nielsen, F. C., 2007, In: Digestive Diseases and Sciences. 52, 8, p. 1783-1789 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Clinical phenotype and gene expression profile in Crohn's disease

Csillag, C., Nielsen, O. H., Borup, R., Nielsen, F. C. & Olsen, J., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 292, 1, p. G298-G304

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Expression of the genes dual oxidase 2, lipocalin 2 and regenerating islet-derived 1 alpha in Crohn's disease

Csillag, C., Nielsen, O. H., Vainer, B., Olsen, J., Dieckgraefe, B. K., Hendel, J., Dupuy, C., Nielsen, F. C., Borup, R. & Vind, I., 2007, In: Scandinavian Journal of Gastroenterology. 42, 4, p. 454-463 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

Gene expression time course in the human skin during elicitation of allergic contact dermatitis

Pedersen, M. B., Skov, L., Menne, T., Johansen, J. D. & Olsen, J., 2007, In: Journal of Investigative Dermatology. 127, 11, p. 2585-2595 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

Treatment response and colonic gene expression in patients with Crohn's disease

Csillag, C., Borup, R., Olsen, J., Nielsen, F. C. & Nielsen, O. H., 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 834-840 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

2006

Cancerbeskyttende gener (tumorsuppressorgener)

Olsen, J., 2006, In: Ugeskrift for læger. 168, 24, p. 2329-2331 2 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Metabolome, transcriptome, and bioinformatic cis-element analyses point to HNF-4 as a central regulator of gene expression during enterocyte differentiation.

Stegmann, A., Hansen, M., Wang, Y., Larsen, J. B., Lund, L. R., Ritié, L., Nicholson, J. K., Quistorff, B., Simon-Assmann, P., Troelsen, J. T. & Olsen, J., 2006, In: Physiological Genomics. 27, 2, p. 141-55 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

81 Citations (Scopus)

1141 Downloads (Pure)

2005

Differentiation-dependent activation of the human intestinal alkaline phosphatase promoter by HNF-4 in intestinal cells.

Olsen, L., Bressendorff, S., Troelsen, J. T. & Olsen, J., 2005, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 289, 2, p. G220-6

Research output: Contribution to journal › Journal article › Research › peer-review

37 Citations (Scopus)

Gene transcripts as potential diagnostic markers for allergic contact dermatitis.

Hansen, M. B., Skov, L., Menné, T. & Olsen, J., 2005, In: Contact Dermatitis. 53, 2, p. 100-6 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

Jørgen Olsen

Research output

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