Research output per year
Research output per year
Personal profile
Primary fields of research
Thue W. Schwartz forsker i appetitregulering og udvikling af lægemidler mod fedme. Han forskersgruppe undersøger især hvordan sult og mæthedssignaler transmitteres fra mave til hjernen. Thue W. Schwartz er medstifter af virksomheden 7TM Pharma, hvor han også fungerer som forskningsdirektør. Virksomheden fokuserer på opdagelse og udvikling af nye lægemidler mod fedme, hvor de første - udsprunget af forskningen på KU - nu bliver afprøvet.Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- Faculty of Health and Medical Sciences
- Eating Disorders
- Obesity
- Molecular Pharmacology
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- 12 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Glucagon-like peptide 1 (GLP-1)
Mueller, T. D., Finan, B., Bloom, S. R., D'Alessio, D., Drucker, D. J., Flatt, P. R., Fritsche, A., Gribble, F., Grill, H. J., Habener, J. F., Holst, J. J., Langhans, W., Meier, J. J., Nauck, M. A., Perez-Tilve, D., Pocai, A., Reimann, F., Sandoval, D. A., Schwartz, T. W., Seeley, R. J., & 5 others, Dec 2019, In: Molecular Metabolism. 30, p. 72-130Research output: Contribution to journal › Review › peer-review
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Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography
Chen, S., Lu, M., Liu, D., Yang, L., Yi, C., Ma, L., Zhang, H., Liu, Q., Frimurer, T. M., Wang, M-W., Schwartz, T. W., Stevens, R. C., Wu, B., Wuthrich, K. & Zhao, Q., 1 Dec 2019, In: Nature Communications. 10, 8 p., 638.Research output: Contribution to journal › Journal article › Research › peer-review
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Microbial fermentation of flaxseed fibers modulates the transcriptome of GPR41-expressing enteroendocrine cells and protects mice against diet-induced obesity
Arora, T., Rudenko, O., Egerod, K. L., Husted, A. S., Kovatcheva-Datchary, P., Akrami, R., Kristensen, M., Schwartz, T. W. & Backhed, F., Mar 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 3, p. E453-E463Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1
Lückmann, M., Trauelsen, M., Bentsen, M. A., Nissen, T. A. D., Martins, J., Fallah, Z., Nygaard, M. M., Papaleo, E., Lindorff-Larsen, K., Schwartz, T. W. & Frimurer, T. M., 2 Apr 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7123-7128Research output: Contribution to journal › Journal article › Research › peer-review
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Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice
Jepsen, S. L., Grunddal, K. V., Wewer Albrechtsen, N. J., Engelstoft, M. S., Gabe, M. B. N., Jensen, E. P., Ørskov, C., Poulsen, S. S., Rosenkilde, M. M., Pedersen, J., Gribble, F. M., Reimann, F., Deacon, C. F., Schwartz, T. W., Christ, A. D., Martin, R. E. & Holst, J. J., Dec 2019, In: A J P: Endocrinology and Metabolism (Online).Research output: Contribution to journal › Journal article › Research › peer-review
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Preassociation between the 5-HT7 serotonin receptor and G protein Gs: molecular determinants and association with low potency activation of adenylyl cyclase
Ulsund, A. H., Dahl, M., Frimurer, T. M., Manfra, O., Schwartz, T. W., Levy, F. O. & Andressen, K. W., 1 Mar 2019, In: FASEB Journal. 33, 3, p. 3870-3886Research output: Contribution to journal › Journal article › Research › peer-review
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Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production
Piccand, J., Vagne, C., Blot, F., Meunier, A., Beucher, A., Strasser, P., Lund, M. L., Ghimire, S., Nivlet, L., Lapp, C., Petersen, N., Engelstoft, M. S., Thibault-Carpentier, C., Keime, C., Correa, S. J., Schreiber, V., Molina, N., Schwartz, T. W., De Arcangelis, A. & Gradwohl, G., Nov 2019, In: Molecular Metabolism. 29, p. 24-39Research output: Contribution to journal › Journal article › Research › peer-review
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The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones
Rudenko, O., Shang, J., Munk, A., Ekberg, J. P., Petersen, N., Engelstoft, M. S., Egerod, K. L., Hjorth, S. A., Wu, M., Feng, Y., Zhou, Y-P., Mokrosinski, J., Thams, P., Reimann, F., Gribble, F., Rehfeld, J. F., Holst, J. J., Treebak, J. T., Howard, A. D. & Schwartz, T. W., Jan 2019, In: Molecular Metabolism. 19, p. 49-64 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Datasets
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Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
Lundø, K. (Creator), Dmytriyeva, O. (Creator), Spøhr, L. (Creator), Goncalves-Alves, E. (Creator), Yao, J. (Creator), Blasco, L. P. (Creator), Trauelsen, M. (Creator), Ponniah, M. (Creator), Severin, M. (Creator), Sandelin, A. (Creator), Kveiborg, M. (Creator), Schwartz, T. W. (Creator) & Pedersen, S. H. F. (Creator), figshare, 2023
DOI: 10.6084/m9.figshare.c.6945608.v1, https://springernature.figshare.com/collections/Lactate_receptor_GPR81_drives_breast_cancer_growth_and_invasiveness_through_regulation_of_ECM_properties_and_Notch_ligand_DLL4/6945608/1
Dataset
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Additional file 1 of Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
Lundø, K. (Creator), Dmytriyeva, O. (Creator), Spøhr, L. (Creator), Goncalves-Alves, E. (Creator), Yao, J. (Creator), Blasco, L. P. (Creator), Trauelsen, M. (Creator), Ponniah, M. (Creator), Severin, M. (Creator), Sandelin, A. (Creator), Kveiborg, M. (Creator), Schwartz, T. W. (Creator) & Pedersen, S. H. F. (Creator), figshare, 2023
DOI: 10.6084/m9.figshare.24628097.v1, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Lactate_receptor_GPR81_drives_breast_cancer_growth_and_invasiveness_through_regulation_of_ECM_properties_and_Notch_ligand_DLL4/24628097/1
Dataset
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Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
Lundø, K. (Creator), Dmytriyeva, O. (Creator), Spøhr, L. (Creator), Goncalves-Alves, E. (Creator), Yao, J. (Creator), Blasco, L. P. (Creator), Trauelsen, M. (Creator), Ponniah, M. (Creator), Severin, M. (Creator), Sandelin, A. (Creator), Kveiborg, M. (Creator), Schwartz, T. W. (Creator) & Pedersen, S. H. F. (Creator), figshare, 2023
DOI: 10.6084/m9.figshare.c.6945608, https://springernature.figshare.com/collections/Lactate_receptor_GPR81_drives_breast_cancer_growth_and_invasiveness_through_regulation_of_ECM_properties_and_Notch_ligand_DLL4/6945608
Dataset
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Additional file 1 of Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
Lundø, K. (Creator), Dmytriyeva, O. (Creator), Spøhr, L. (Creator), Goncalves-Alves, E. (Creator), Yao, J. (Creator), Blasco, L. P. (Creator), Trauelsen, M. (Creator), Ponniah, M. (Creator), Severin, M. (Creator), Sandelin, A. (Creator), Kveiborg, M. (Creator), Schwartz, T. W. (Creator) & Pedersen, S. H. F. (Creator), figshare, 2023
DOI: 10.6084/m9.figshare.24628097, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Lactate_receptor_GPR81_drives_breast_cancer_growth_and_invasiveness_through_regulation_of_ECM_properties_and_Notch_ligand_DLL4/24628097
Dataset