Anna Elisabetta Salcini

2018

JMJD-1.2 controls multiple histone post-translational modifications in germ cells and protects the genome from replication stress

Myers, T. R., Amendola, P. G., Lussi, Y. C. & Salcini, A. E., 1 Dec 2018, In: Scientific Reports. 8, p. 1-11 11 p., 3765.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

52 Downloads (Pure)

Proteomic Characterization of Caenorhabditis elegans Larval Development

Xia, T., Horton, E. R., Salcini, A. E., Pocock, R., Cox, T. R. & Erler, J. T., Jan 2018, In: Proteomics. 18, 2, p. 1-7 7 p., 1700238.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

2017

JMJD-1.2/PHF8 controls axon guidance by regulating Hedgehog-like signaling

Riveiro, A., Mariani, L., Malmberg, K. E., Amendola, P. G., Peltonen, J., Wong, G. & Salcini, A. E., 1 Mar 2017, In: Development (Cambridge, England). 144, 5, p. 856-865 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity

Amendola, P. G., Zaghet, N., Ramalho, J. J., Johansen, J. V., Boxem, M. & Salcini, A. E., Feb 2017, In: P L o S Genetics. 13, 2, 24 p., e1006632.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

59 Downloads (Pure)

2016

Dangerous R loops form in the absence of H3K9 methylation

Salcini, A. E., 1 Nov 2016, In: Nature Genetics. 48, 11, p. 1299-1300 2 p.

Research output: Contribution to journal › Letter

Dynamic changes of histone H3 marks during Caenorhabditis elegans lifecycle revealed by middle-down proteomics

Sidoli, S., Vandamme, J., Salcini, A. E. & Jensen, O. N., 1 Feb 2016, In: Proteomics. 16, 3, p. 459-64 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Impaired removal of H3K4 methylation affects cell fate determination and gene transcription

Lussi, Y. C., Mariani, L., Rundsten, C. F., Peltonen, J., Myers, T. R., Krag, C., Wong, G. & Salcini, A. E., 15 Oct 2016, In: Development (Cambridge, England). 143, 20, p. 3751-3762

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

The H3K4me3/2 histone demethylase RBR-2 controls axon guidance by repressing the actin-remodeling gene wsp-1

Mariani, L., Lussi, Y. C., Vandamme, J., Riveiro, A. & Salcini, A. E., 1 Mar 2016, In: Development (Cambridge, England). 143, 5, p. 851-63 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

2015

EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK/FOXM1-Dependent Manner

Kim, S-H., Joshi, K., Ezhilarasan, R., Myers, T. R., Siu, J., Gu, C., Nakano-Okuno, M., Taylor, D., Minata, M., Sulman, E. P., Lee, J., Bhat, K. P. L., Salcini, A. E. & Nakano, I., 10 Feb 2015, In: Stem Cell Reports.

Research output: Contribution to journal › Journal article › Research › peer-review

106 Citations (Scopus)

H3K23me2 is a new heterochromatic mark in Caenorhabditis elegans

Vandamme, J., Sidoli, S., Mariani, L., Friis, C., Christensen, J., Helin, K., Jensen, O. N. & Salcini, A. E., 1 Oct 2015, In: Nucleic Acids Research. 43, 20, p. 9694-710 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

2013

A snapshot of the physical and functional wiring of the Eps15 homology domain network in the nematode

Tsushima, H., Malabarba, M. G., Confalonieri, S., Senic-Matuglia, F., Verhoef, L. G. G. C., Bartocci, C., D'Ario, G., Cocito, A., Di Fiore, P. P. & Salcini, A. E., 12 Feb 2013, In: PloS one. 8, 2, p. e56383

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

1144 Downloads (Pure)

Catalytic-independent roles of UTX-1 in C. elegans development

Vandamme, J. & Salcini, A. E., 1 Apr 2013, In: Worm. 2, 2, p. e22188

Research output: Contribution to journal › Journal article › Research › peer-review

2012

The C. elegans H3K27 Demethylase UTX-1 Is Essential for Normal Development, Independent of Its Enzymatic Activity

Vandamme, J., Buchhorn, G. L., Sidoli, S., Di Schiavi, E., Nørregaard Jensen, O. & Salcini, A. E., May 2012, In: P L o S Genetics (Online). 8, 5, p. e1002647

Research output: Contribution to journal › Journal article › Research › peer-review

43 Citations (Scopus)

2010

A Functional Link between the Histone Demethylase PHF8 and the Transcription Factor ZNF711 in X-Linked Mental Retardation

Kleine-Kohlbrecher, D., Christensen, J., Vandamme, J., Abarrategui, I., Bak, M., Tommerup, N., Shi, X., Gozani, O., Rappsilber, J., Salcini, A. E. & Helin, K., 23 Apr 2010, In: Molecular Cell. 38, 2, p. 165-78 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

148 Citations (Scopus)

PI3KC2{alpha}, a class II PI3K, is required for dynamin-independent internalization pathways

Krag, C., Malmberg, E. K. & Salcini, A. E., 15 Dec 2010, In: Journal of Cell Science.

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

2007

Caenorhabditis elegans intersectin: a synaptic protein regulating neurotransmission.

Rose, S., Malabarba, M. G., Krag, C., Schultz, A., Tsushima, H., Di Fiore, P. P. & Salcini, A. E., 2007, In: Molecular Biology of the Cell. 18, 12, p. 5091-9 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.

Christensen, J., Agger, K., Cloos, P. A. C., Pasini, D., Rose, S., Sennels, L., Rappsilber, J., Hansen, K., Salcini, A. E. & Helin, K., 2007, In: Cell. 128, 6, p. 1063-76 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

390 Citations (Scopus)

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.

Agger, K., Cloos, P. A. C., Christensen, J., Pasini, D., Rose, S., Rappsilber, J., Issaeva, I., Canaani, E., Salcini, A. E. & Helin, K., 2007, In: Nature. 449, 7163, p. 731-4 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

891 Citations (Scopus)

2005

TTP specifically regulates the internalization of the transferrin receptor.

Tosoni, D., Puri, C., Confalonieri, S., Salcini, A. E., De Camilli, P., Tacchetti, C. & Di Fiore, P. P., 2005, In: Cell. 123, 5, p. 875-88 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

80 Citations (Scopus)

2003

EH and UIM: endocytosis and more.

Polo, S., Confalonieri, S., Salcini, A. E. & Di Fiore, P. P., 2003, In: Science's STKE : signal transduction knowledge environment. 2003, 213, p. re17

Research output: Contribution to journal › Journal article › Research › peer-review

89 Citations (Scopus)

2001

The Eps15 C. elegans homologue EHS-1 is implicated in synaptic vesicle recycling.

Salcini, A. E., Hilliard, M. A., Croce, A., Arbucci, S., Luzzi, P., Tacchetti, C., Daniell, L., De Camilli, P., Pelicci, P. G., Di Fiore, P. P. & Bazzicalupo, P., 2001, In: Nature Cell Biology. 3, 8, p. 755-60 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

56 Citations (Scopus)

2000

Numb is an endocytic protein.

Santolini, E., Puri, C., Salcini, A. E., Gagliani, M. C., Pelicci, P. G., Tacchetti, C. & Di Fiore, P. P., 2000, In: Journal of Cell Biology. 151, 6, p. 1345-52 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

286 Citations (Scopus)

Tyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis.

Confalonieri, S., Salcini, A. E., Puri, C., Tacchetti, C. & Di Fiore, P. P., 2000, In: Journal of Cell Biology. 150, 4, p. 905-12 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

114 Citations (Scopus)

1999

Epidermal growth factor pathway substrate 15, Eps15.

Salcini, A. E., Chen, H., Iannolo, G., De Camilli, P. & Di Fiore, P. P., 1999, In: International Journal of Biochemistry & Cell Biology. 31, 8, p. 805-9 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

80 Citations (Scopus)

Eps15 is recruited to the plasma membrane upon epidermal growth factor receptor activation and localizes to components of the endocytic pathway during receptor internalization.

Torrisi, M. R., Lotti, L. V., Belleudi, F., Gradini, R., Salcini, A. E., Confalonieri, S., Pelicci, P. G. & Di Fiore, P. P., 1999, In: Molecular Biology of the Cell. 10, 2, p. 417-34 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

91 Citations (Scopus)

The EH network.

Santolini, E., Salcini, A. E., Kay, B. K., Yamabhai, M. & Di Fiore, P. P., 1999, In: Experimental Cell Research. 253, 1, p. 186-209 23 p.

Research output: Contribution to journal › Journal article › Research › peer-review

115 Citations (Scopus)

The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport.

Doria, M., Salcini, A. E., Colombo, E., Parslow, T. G., Pelicci, P. G. & Di Fiore, P. P., 1999, In: Journal of Cell Biology. 147, 7, p. 1379-84 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

39 Citations (Scopus)

The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module.

Rosenthal, J. A., Chen, H., Slepnev, V. I., Pellegrini, L., Salcini, A. E., Di Fiore, P. P. & De Camilli, P., 1999, In: Journal of Biological Chemistry. 274, 48, p. 33959-65 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

144 Citations (Scopus)

1998

Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization.

Coda, L., Salcini, A. E., Confalonieri, S., Pelicci, G., Sorkina, T., Sorkin, A., Pelicci, P. G. & Di Fiore, P. P., 1998, In: Journal of Biological Chemistry. 273, 5, p. 3003-12 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

68 Citations (Scopus)

Recognition specificity of individual EH domains of mammals and yeast.

Paoluzi, S., Castagnoli, L., Lauro, I., Salcini, A. E., Coda, L., Fre', S., Confalonieri, S., Pelicci, P. G., Di Fiore, P. P. & Cesareni, G., 1998, In: EMBO Journal. 17, 22, p. 6541-50 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

98 Citations (Scopus)

1997

Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module.

Salcini, A. E., Confalonieri, S., Doria, M., Santolini, E., Tassi, E., Minenkova, O., Cesareni, G., Pelicci, P. G. & Di Fiore, P. P., 1997, In: Genes & Development. 11, 17, p. 2239-49 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

277 Citations (Scopus)

Mapping of the molecular determinants involved in the interaction between eps15 and AP-2.

Iannolo, G., Salcini, A. E., Gaidarov, I., Goodman, O. B., Baulida, J., Carpenter, G., Pelicci, P. G., Di Fiore, P. P. & Keen, J. H., 1997, In: Cancer Research. 57, 2, p. 240-5 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

85 Citations (Scopus)

Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

Migliaccio, E., Mele, S., Salcini, A. E., Pelicci, G., Lai, K. M., Superti-Furga, G., Pawson, T., Di Fiore, P. P., Lanfrancone, L. & Pelicci, P. G., 1997, In: EMBO Journal. 16, 4, p. 706-16 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

348 Citations (Scopus)

Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15.

Haffner, C., Takei, K., Chen, H., Ringstad, N., Hudson, A., Butler, M. H., Salcini, A. E., Di Fiore, P. P. & De Camilli, P., 1997, In: FEBS Letters. 419, 2-3, p. 175-80 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

129 Citations (Scopus)

1996

Sch proteins are localized on endoplasmic reticulum membranes and are redistributed after tyrosine kinase receptor activation.

Lotti, L. V., Lanfrancone, L., Migliaccio, E., Zompetta, C., Pelicci, G., Salcini, A. E., Falini, B., Pelicci, P. G. & Torrisi, M. R., 1996, In: Molecular and Cellular Biology. 16, 5, p. 1946-54 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

66 Citations (Scopus)

Shc adaptor proteins are key transducers of mitogenic signaling mediated by the G protein-coupled thrombin receptor.

Chen, Y., Grall, D., Salcini, A. E., Pelicci, P. G., Pouysségur, J. & Van Obberghen-Schilling, E., 1996, In: EMBO Journal. 15, 5, p. 1037-44 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

103 Citations (Scopus)

1995

A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution.

Wong, W. T., Schumacher, C., Salcini, A. E., Romano, A., Castagnino, P., Pelicci, P. G. & Di Fiore, P. P., 1995, In: Proceedings of the National Academy of Science of the United States of America. 92, 21, p. 9530-4 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

127 Citations (Scopus)

Constitutive phosphorylation of eps8 in tumor cell lines: relevance to malignant transformation.

Matoskova, B., Wong, W. T., Salcini, A. E., Pelicci, P. G. & Di Fiore, P. P., 1995, In: Molecular and Cellular Biology. 15, 7, p. 3805-12 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

68 Citations (Scopus)

Constitutive phosphorylation of Shc proteins in human tumors.

Pelicci, G., Lanfrancone, L., Salcini, A. E., Romano, A., Mele, S., Grazia Borrello, M., Segatto, O., Di Fiore, P. P. & Pelicci, P. G., 1995, In: Oncogene. 11, 5, p. 899-907 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

117 Citations (Scopus)

The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein.

Pelicci, G., Giordano, S., Zhen, Z., Salcini, A. E., Lanfrancone, L., Bardelli, A., Panayotou, G., Waterfield, M. D., Ponzetto, C. & Pelicci, P. G., 1995, In: Oncogene. 10, 8, p. 1631-8 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

174 Citations (Scopus)

1994

Chromosome locations of genes encoding human signal transduction adapter proteins, Nck (NCK), Shc (SHC1), and Grb2 (GRB2).

Huebner, K., Kastury, K., Druck, T., Salcini, A. E., Lanfrancone, L., Pelicci, G., Lowenstein, E., Li, W., Park, S. H. & Cannizzaro, L., 1994, In: Genomics. 22, 2, p. 281-7 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Formation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins.

Salcini, A. E., McGlade, J., Pelicci, G., Nicoletti, I., Pawson, T. & Pelicci, P. G., 1994, In: Oncogene. 9, 10, p. 2827-36 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

194 Citations (Scopus)

1992

Structural and functional organization of the HF.10 human zinc finger gene (ZNF35) located on chromosome 3p21-p22.

Lanfrancone, L., Pengue, G., Pandolfi, P. P., Salcini, A. E., Giacomucci, A., Longo, L., Donti, E., De Luca, P., La Mantia, G. & Pelicci, P. G., 1992, In: Genomics. 12, 4, p. 720-8 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Anna Elisabetta Salcini

Research output

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