Department of Cellular and Molecular Medicine

2019

Curvature- and Phase-Induced Protein Sorting Quantified in Transfected Cell-Derived Giant Vesicles

Moreno-Pescador, G., Florentsen, C. D., Østbye, H., Sønder, S. L., Boye, T. L., Veje, E. L., Sonne, A. K., Semsey, S., Nylandsted, J., Daniels, R. & Bendix, P. M., 25 Jun 2019, In: ACS Nano. 13, 6, p. 6689-6701

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

CXCR7 signaling promotes breast cancer survival in response to mesenchymal stromal stem cell-derived factors

Al-toub, M., Almohawes, M., Vishnubalaji, R., Alfayez, M., Aldahmash, A., Kassem, M. & Alajez, N. M., 2019, In: Cell Death Discovery. 5, 1, 9 p., 87.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

15 Downloads (Pure)

Dendrons as delivery vectors for oligonucleotide drugs

Gabas, I. M., 11 Jan 2019

Research output: Book/Report › Ph.D. thesis

Developmental differences in the expression of ABC transporters at rat brain barrier interfaces following chronic exposure to diallyl sulfide

Koehn, L. M., Dziegielewska, K. M., Møllgård, K., Saudrais, E., Strazielle, N., Ghersi-Egea, J-F., Saunders, N. R. & Habgood, M. D., 1 Dec 2019, In: Scientific Reports. 9, 1, p. 5998

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Diagnostic yield of high-density versus low-density EEG: The effect of spatial sampling, timing and duration of recording

Bach Justesen, A., Foged, M. T., Fabricius, M., Skaarup, C., Hamrouni, N., Martens, T., Paulson, O. B., Pinborg, L. H. & Beniczky, S., 2019, In: Clinical Neurophysiology. 130, 11, p. 2060-2064 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells

Zheng, J., Croteau, D. L., Bohr, V. & Akbari, M., 7 May 2019, In: Nucleic Acids Research. 47, 8, p. 4086–4110

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor

Hansen, L. H., Madsen, T. D., Goth, C. K., Clausen, H., Chen, Y., Dzhoyashvili, N., Iyer, S. R., Sangaralingham, S. J., Burnett, J. C., Rehfeld, J. F., Vakhrushev, S. Y., Schjoldager, K. T. & Goetze, J. P., 23 Aug 2019, In: Journal of Biological Chemistry. 294, 34, p. 12567-12578 12 p.

Research output: Contribution to journal › Review › peer-review

17 Citations (Scopus)

DNA replication stress and its impact on chromosome segregation and tumorigenesis

Zhang, B. N., Bueno Venegas, A., Hickson, I. D. & Chu, W. K., Apr 2019, In: Seminars in Cancer Biology. 55, p. 61-69

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Downregulation of TdT Expression through Splicing Modulation by Antisense Peptide Nucleic Acid (PNA)

Montazersaheb, S., Kazemi, M., Nabat, E., Nielsen, P. E. & Hejazi, M. S., 2019, In: Current Pharmaceutical Biotechnology. 20, 2, p. 168-178 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

dTcf/Pangolin suppresses growth and tumor formation in Drosophila

Song, S., Andrejeva, D., Freitas, F. C. P., Cohen, S. M. & Herranz, H., 9 Jul 2019, In: Proceedings of the National Academy of Sciences of the United States of America. p. 14055-14064 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Effect of local thermoplasmonic heating on biological membranes

Moreno-Pescador, G. S., Qoqaj, I., Thusgaard Ruhoff, V., Iversen, J., Nylandsted, J. & Bendix, P. M., 9 Sept 2019, In: Proceedings of S P I E - International Society for Optical Engineering. 11083, 19 p., 110830M.

Research output: Contribution to journal › Conference article › Research › peer-review

1 Citation (Scopus)

Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex

Zhang, G., Kruse, T., Guasch Boldú, C., Garvanska, D. H., Coscia, F., Mann, M., Barisic, M. & Nilsson, J., 1 Apr 2019, In: E M B O Journal. 38, 7, e100977.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

Enhanced cerebral branched-chain amino acid metabolism in R6/2 mouse model of Huntington's disease

Andersen, J. V., Skotte, N. H., Aldana, B. I., Nørremølle, A. & Waagepetersen, H. S., 1 Jun 2019, In: Cellular and Molecular Life Sciences. 76, 12, p. 2449-2461

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Erratum: Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions (Journal of Biological Chemistry (2018) 293 (7408-7422) DOI: 10.1074/jbc.M117.817981)

Wang, S., Mao, Y., Narimatsu, Y., Ye, Z., Tian, W., Goth, C. K., Lira-Navarrete, E., Pedersen, N. B., Benito-Vicente, A., Martin, C., Uribe, K. B., Hurtado-Guerrero, R., Christoffersen, C., Seidah, N. G., Nielsen, R., Christensen, E. I., Hansen, L., Bennett, E. P., Vakhrushev, S. Y., Schjoldager, K. T., & 1 othersClausen, H., 24 May 2019, In: Journal of Biological Chemistry. 294, 21, 1 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

2 Citations (Scopus)

Esc2 promotes telomere stability in response to DNA replication stress

Jørgensen, S. W., Liberti, S. E., Larsen, N. B., Lisby, M., Mankouri, H. W. & Hickson, I. D., 2019, In: Nucleic Acids Research. 47, 9, p. 4597-4611 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

16 Downloads (Pure)

Evaluating the involvement of cerebral microvascular endothelial Na⁺/K⁺-ATPase and Na⁺-K⁺-2Cl^- co-transporter in electrolyte fluxes in an in vitro blood-brain barrier model of dehydration

Lykke, K., Assentoft, M., Hørlyck, S., Helms, H. C. C., Stoica, A., Toft-Bertelsen, T. L., Tritsaris, K., Vilhardt, F., Brodin, B. & MacAulay, N., 1 Mar 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, 3, p. 497-512

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Evaluation of temocillin for phenotypic carbapenemase screening of Escherichia coli and Salmonella enterica isolates in relation to the presence of genes encoding ESBLs and carbapenemase production

Cavaco, L. M., Hansen, F., Mushtaq, S., Hill, R. L. R., Woodford, N., Le Hello, S., Hendriksen, R. S., Hammerum, A. M. & Hasman, H., 1 Mar 2019, In: The Journal of antimicrobial chemotherapy. 74, 3, p. 639-644 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics

Narimatsu, Y., Joshi, H. J., Schjoldager, K. T., Hintze, J., Halim, A., Steentoft, C., Nason, R., Mandel, U., Bennett, E. P., Clausen, H. & Vakhrushev, S. Y., 2019, In: Molecular and Cellular Proteomics. 18, 7, p. 1396-1409

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome

Hu, T., Buus, T. B., Krejsgaard, T., Nansen, A., Lundholt, B. K., Spee, P., Fredholm, S., Petersen, D. L., Blümel, E., Gluud, M., Monteiro, M. N., Willerslev-Olsen, A., Andersen, M. H., Straten, P. T., Met, Ö., Stolearenco, V., Fogh, H., Gniadecki, R., Nastasi, C., Litman, T., & 3 othersWoetmann, A., Gjerdrum, L. M. R. & Ødum, N., 1 Aug 2019, In: OncoTarget. 10, 47, p. 4894-4906 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Expression profiling of immune inhibitory Siglecs and their ligands in patients with glioma

Santegoets, K. C. M., Gielen, P. R., Büll, C., Schulte, B. M., Kers-Rebel, E. D., Küsters, B., Bossman, S. A. J. F. H., Ter Laan, M., Wesseling, P. & Adema, G. J., 1 Jun 2019, In: Cancer immunology, immunotherapy : CII.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Extracellular and intracellular small-molecule galectin-3 inhibitors

Stegmayr, J., Zetterberg, F., Carlsson, M. C., Huang, X., Sharma, G., Kahl-Knutson, B., Schambye, H., Nilsson, U. J., Oredsson, S. & Leffler, H., 2019, In: Scientific Reports. 9, 1, 12 p., 2186.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

27 Downloads (Pure)

Extracranial activation of ATP-sensitive potassium channels induces vasodilation without nociceptive effects

Al-Karagholi, M. A-M., Ghanizada, H., Hansen, J. M., Aghazadeh, S., Skovgaard, L. T., Olesen, J. & Ashina, M., 1 Dec 2019, In: Cephalalgia.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Fast and Quantitative Identification of Ex Vivo Precise Genome Targeting-Induced Indel Events by IDAA

König, S., Yang, Z., Wandall, H. H., Mussolino, C. & Bennett, E. P., 2019, CRISPR Gene Editing. Luo, Y. (ed.). Humana Press, p. 45-66 22 p. (Methods in Molecular Biology, Vol. 1961).

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

1 Citation (Scopus)

From powerhouse to perpetrator—mitochondria in health and disease

Fakouri, N. B., Hansen, T. L., Desler, C., Anugula, S. & Rasmussen, L. J., 2019, In: Biology. 8, 2, 15 p., 35.

Research output: Contribution to journal › Review › peer-review

10 Citations (Scopus)

44 Downloads (Pure)

Functional Differences between Synaptic Mitochondria from the Striatum and the Cerebral Cortex

Petersen, M. H., Willert, C. W., Andersen, J. V., Waagepetersen, H. S., Skotte, N. H. & Nørremølle, A., 15 May 2019, In: Neuroscience. 406, p. 432-443 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding

Tian, E., Wang, S., Zhang, L., Zhang, Y., Malicdan, M. C., Mao, Y., Christoffersen, C., Tabak, L. A., Schjoldager, K. T. & Ten Hagen, K. G., 10 Dec 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 50, p. 25196-25202 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Generation and characterization of a PICH-deficient mouse model

Albers, E., 29 Mar 2019

Research output: Book/Report › Ph.D. thesis

Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia

Nielsen, J. E. & International FTD-Genomics Consortium (IFGC), 2019, In: Scientific Reports. 9, 1, 10 p., 10854.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

38 Downloads (Pure)

Ghrelin-mediated improvements in the metabolic phenotype in the R6/2 mouse model of Huntington's disease

Rudenko, O., Springer, C., Skov, L. J., Madsen, A. N., Hasholt, L., Nørremølle, A. & Holst, B., 2019, In: Journal of Neuroendocrinology. 31, 7 (SI), 14 p., e12699.

Research output: Contribution to journal › Conference article › Research › peer-review

3 Citations (Scopus)

GIGYF1/2-Driven Cooperation between ZNF598 and TTP in Posttranscriptional Regulation of Inflammatory Signaling

Tollenaere, M. A. X., Tiedje, C., Rasmussen, S., Nielsen, J. C., Vind, A. C., Blasius, M., Batth, T. S., Mailand, N., Olsen, J. V., Gaestel, M. & Bekker-Jensen, S., 26 Mar 2019, In: Cell Reports. 26, 13, p. 3511-3521.e4 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

5 Downloads (Pure)

Glyco-DIA: a method for quantitative O-glycoproteomics with in silico-boosted glycopeptide libraries

Ye, Z., Mao, Y., Clausen, H. & Vakhrushev, S. Y., 1 Sept 2019, In: Nature Methods. 16, 9, p. 902-910 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Guardians of the genome - ZGRF1 as a novel DNA repair factor - Identification of novel ultrafine anaphase bridge localizing factors

Brannvoll, A., 21 Mar 2019

Research output: Book/Report › Ph.D. thesis

Haploinsufficiency of ARHGAP42 is associated with hypertension

Fjorder, A. S., Rasmussen, M. B., Mehrjouy, M. M., Nazaryan-Petersen, L., Hansen, C., Bak, M., Grarup, N., Nørremølle, A., Larsen, L. A., Vestergaard, H., Hansen, T., Tommerup, N. & Bache, I., 1 Aug 2019, In: European Journal of Human Genetics. 27, 8, p. 1296-1303 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

High efficacy full allelic CRISPR/Cas9 gene editing in tetraploid potato

Johansen, I. E., Liu, Y., Jorgensen, B., Bennett, E. P., Andreasson, E., Nielsen, K. L., Blennow, A. & Petersen, B. L., 1 Dec 2019, In: Scientific Reports. 9

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

High-throughput sequencing reveals no viral pathogens in eight cases of ocular adnexal extranodal marginal zone B-cell lymphoma

Mollerup, S., Mikkelsen, L. H., Hansen, A. J. & Heegaard, S., Aug 2019, In: Experimental Eye Research. 185, 5 p., 107677.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Hip-fracture osteosynthesis training: exploring learning curves and setting proficiency standards

Gustafsson, A., Pedersen, P., Rømer, T. B., Viberg, B., Palm, H. & Konge, L., 4 Jul 2019, In: Acta Orthopaedica. 90, 4, p. 348-353 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

15 Downloads (Pure)

Human exonuclease 1 (EXO1) regulatory functions in DNA replication with putative roles in cancer

Keijzers, G., Bakula, D., Petr, M. A., Madsen, N. G. K., Teklu, A., Mkrtchyan, G., Osborne, B. & Scheibye-Knudsen, M., 2019, In: International Journal of Molecular Sciences. 20, 1, 15 p., 74.

Research output: Contribution to journal › Review › peer-review

13 Citations (Scopus)

59 Downloads (Pure)

Human granulosa cells function as innate immune cells executing an inflammatory reaction during ovulation: a microarray analysis

Poulsen, L. L. C., Englund, A. L. M., Wissing, M. L. M., Yding Andersen, C., Borup, R. & Grøndahl, M. L., 2019, In: Molecular and Cellular Endocrinology. 486, p. 34-46 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

IL-6 release from muscles during exercise is stimulated by lactate-dependent protease activity

Hojman, P., Brolin, C., Nørgaard-Christensen, N., Dethlefsen, C., Lauenborg, B., Olsen, C. K., Åbom, M. M., Krag, T., Gehl, J. & Pedersen, B. K., 1 May 2019, In: American journal of physiology. Endocrinology and metabolism. 316, 5, p. E940-E947

Research output: Contribution to journal › Journal article › Research › peer-review

Impaired serum inhibin-B and number of germ cells in boys with cryptorchidism following heavily gestational maternal smoking

Hildorf, S., Clasen-Linde, E., Dong, L., Cortes, D. & Thorup, J., Apr 2019, In: Journal of Pediatric Surgery.

Research output: Contribution to journal › Journal article › Research › peer-review

Improved CRISPR/Cas9 gene editing by fluorescence activated cell sorting of green fluorescence protein tagged protoplasts

Petersen, B. L., Möller, S. R., Mravec, J., Jørgensen, B., Christensen, M., Liu, Y., Wandall, H. H., Bennett, E. P. & Yang, Z., 17 Jun 2019, In: BMC Biotechnology. 19, p. 1-12 36.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

49 Downloads (Pure)

Insights into an unusual Auxiliary Activity 9 family member lacking the histidine brace motif of lytic polysaccharide monooxygenases

Frandsen, K. E. H., Tovborg, M., Jørgensen, C. I., Spodsberg, N., Rosso, M-N., Hemsworth, G. R., Garman, E. F., Grime, G. W., Poulsen, J-C. N., Batth, T. S., Miyauchi, S., Lipzen, A., Daum, C., Grigoriev, I. V., Johansen, K. S., Henrissat, B., Berrin, J-G. & Lo Leggio, L., 8 Nov 2019, In: The Journal of Biological Chemistry. 294, p. 17117-17130 24 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Inverted papilloma of the conjunctiva

Ramberg, I., Sjö, N. C., Bonde, J. H. & Heegaard, S., 1 Feb 2019, In: BMJ Open Ophthalmology. 4, 1, 7 p., e000193.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

14 Downloads (Pure)

KIAA1199 is a secreted molecule that enhances osteoblastic stem cell migration and recruitment

Chen, L., Shi, K., Andersen, T. L., Qiu, W. & Kassem, M., 1 Feb 2019, In: Cell Death & Disease. 10, 2, p. 126

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Lamin A/C promotes DNA base excision repair

Maynard, S., Keijzers, G., Akbari, M., Ezra, M. B., Hall, A., Morevati, M., Scheibye-Knudsen, M., Gonzalo, S., Bartek, J. & Bohr, V. A., 16 Dec 2019, In: Nucleic Acids Research.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Lansoprazole inhibits the cysteine protease legumain by binding to the active site

Bosnjak, T., Solberg, R., Hemati, P. D., Jafari, A., Kassem, M. & Johansen, H. T., Aug 2019, In: Basic & Clinical Pharmacology & Toxicology. 125, 2, p. 89-99 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Long-Term Outcomes of Partial Oral Treatment of Endocarditis

Bundgaard, H., Ihlemann, N., Gill, S. U., Bruun, N. E., Elming, H., Madsen, T., Jensen, K. T., Fursted, K., Christensen, J. J., Schultz, M., Østergaard, L., Rosenvinge, F., Schønheyder, H. C., Helweg-Larsen, J., Fosbøll, E. L., Køber, L., Torp-Pedersen, C., Tønder, N., Moser, C. & Iversen, K., 4 Apr 2019, In: The New England Journal of Medicine. 380, 14, p. 1373-1374 2 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Mass spectrometry-based glycomics and glycoproteomics

Ye, Z., 29 May 2019

Research output: Book/Report › Ph.D. thesis

Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs

Zielinska, A. P., Bellou, E., Sharma, N., Frombach, A. S., Seres, K. B., Gruhn, J. R., Blayney, M., Eckel, H., Moltrecht, R., Elder, K., Hoffmann, E. R. & Schuh, M., 2019, In: Current Biology. 29, 22, p. 3749-3765.e7

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

2 Downloads (Pure)

MERTK Acts as a costimulatory receptor on human cd8 t cells

Peeters, M. J. W., Dulkeviciute, D., Draghi, A., Ritter, C., Rahbech, A., Skadborg, S. K., Seremet, T., Simoes, A. M. C., Martinenaite, E., Halldorsdottir, H. R., Andersen, M. H., Olofsson, G. H., Svane, I. M., Rasmussen, L. J., Met, O., Becker, J. C., Donia, M., Desler, C. & Straten, P. T., 2019, In: Cancer Immunology Research. 7, 9, p. 1472-1484 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Department of Cellular and Molecular Medicine

Research output

Search results