Research output per year
Research output per year
Personal profile
Primary fields of research
Our research has been focused on understanding the biology of mesenchymal (skeletal) stem cells, their role in skeletal tissue homeostasis, and their applications in regenerative medicine and cell-based therapies.
Current research
- Understanding mechanisms regulating differentiation fate of mesenchymal (skeletal) stem cells (MSC)
- Role of MSC-secreted factors in pathophysiology of cancer/inflammation-induced bone loss
- Role of complement system in regulation of stem cell differentiation
- Understanding the biology of bone marrow adipose tissue and its contribution to systemic energy metabolism
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- Faculty of Health and Medical Sciences
- Mesenchymal (Skeletal) Stem Cell
- Osteoblast
- Adipocyte
- bone marrow adipose tissue
- cancer/inflammation/age-related bone loss
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Dive into the research topics where Abbas Jafari Kermani is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 6 Similar Profiles
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Aging and lineage allocation changes of bone marrow skeletal (stromal) stem cells
Nehlin, J. O., Jafari, A., Tencerova, M. & Kassem, M., Jun 2019, In: Bone.Research output: Contribution to journal › Journal article › Research › peer-review
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Lansoprazole inhibits the cysteine protease legumain by binding to the active site
Bosnjak, T., Solberg, R., Hemati, P. D., Jafari, A., Kassem, M. & Johansen, H. T., Aug 2019, In: Basic & Clinical Pharmacology & Toxicology. 125, 2, p. 89-99 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TAFA2 Induces Skeletal (Stromal) Stem Cell Migration Through Activation of Rac1-p38 Signaling
Jafari, A., Isa, A., Chen, L., Ditzel, N., Zaher, W., Harkness, L., Johnsen, H. E., Abdallah, B. M., Clausen, C. & Kassem, M., Mar 2019, In: Stem Cells.Research output: Contribution to journal › Journal article › Research › peer-review
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CRMP4 Inhibits Bone Formation by Negatively Regulating BMP and RhoA Signaling
Abdallah, B. M., Figeac, F., Larsen, K. H., Ditzel, N., Keshari, P., Isa, A., Jafari Kermani, A., Andersen, T. L., Delaisse, J-M., Goshima, Y., Ohshima, T. & Kassem, M., May 2017, In: Journal of Bone and Mineral Research. 32, 5, p. 913-926 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Legumain Regulates Differentiation Fate of Human Bone Marrow Stromal Cells and Is Altered in Postmenopausal Osteoporosis
Jafari Kermani, A., Qanie, D., Andersen, T. L., Zhang, Y., Chen, L., Postert, B., Parsons, S., Ditzel, N., Khosla, S., Johansen, H. T., Kjærsgaard-Andersen, P., Delaisse, J-M., Abdallah, B. M., Hesselson, D., Solberg, R. & Kassem, M., 14 Feb 2017, In: Stem Cell Reports. 8, 2, p. 373-386 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence of two distinct functionally specialized fibroblast lineages in breast stroma
Morsing, M., Klitgaard, M. C., Jafari Kermani, A., Villadsen, R., Kassem, M. S. E-D., Petersen, O. W. & Rønnov-Jessen, L., 3 Nov 2016, In: Breast Cancer Research (Online). 18, 11 p., 108.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacological Inhibition of Protein Kinase G1 Enhances Bone Formation by Human Skeletal Stem Cells Through Activation of RhoA-Akt Signaling
Kermani, A. J., Siersbaek, M. S., Chen, L., Qanie, D., Zaher, W., Abdallah, B. M. & Kassem, M., 1 Jul 2015, In: Stem Cells. 33, 7, p. 2219-2231 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Skeletal (stromal) stem cells: An update on intracellular signaling pathways controlling osteoblast differentiation
Abdallah, B. M., Kermani, A. J., Zaher, W., Qiu, W. & Kassem, M., 1 Jan 2015, In: Bone. 70, p. 28-36 9 p.Research output: Contribution to journal › Journal article › Research › peer-review