Research output per year
Research output per year
Search results
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2016
Recent Insights into Cell Surface Heparan Sulphate Proteoglycans and Cancer
Couchman, J. R., Multhaupt, H. & Sanderson, R. D., 2016, In: F1000Research. 5, 9 p., 1541.Research output: Contribution to journal › Review › peer-review
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Reciprocal signals between microglia and neurons regulate alpha-synuclein secretion by exophagy through a neuronal cJU-N-Nterminal kinase-signaling axis
Christensen, D. P., Ejlerskov, P., Rasmussen, I. & Vilhardt, F., 8 Mar 2016, In: Journal of Neuroinflammation. 13, 21 p., 59.Research output: Contribution to journal › Journal article › Research › peer-review
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Redundant and nonredundant roles for Cdc42 and Rac1 in lymphomas developed in NPM-ALK transgenic mice
Choudhari, R., Minero, V. G., Menotti, M., Pulito, R., Brakebusch, C., Compagno, M., Voena, C., Ambrogio, C. & Chiarle, R., 10 Mar 2016, In: Blood. 127, 10, p. 1297-306 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regional tumour glutamine supply affects chromatin and cell identity
Højfeldt, J. W. & Helin, K., 28 Sept 2016, In: Nature Cell Biology. 18, 10, p. 1027-9 3 p.Research output: Contribution to journal › Letter
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Regulating retrotransposon activity through the use of alternative transcription start sites
Persson, J., Steglich, B., Smialowska, A., Boyd, M., Lange, J. B., Andersson, R., Schurra, C., Arcangioli, B., Sandelin, A. G., Nielsen, O. & Ekwall, K., 1 May 2016, In: E M B O Reports. 17, 5, p. 753-768 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation
López-Posadas, R., Becker, C., Günther, C., Tenzer, S., Amann, K., Billmeier, U., Atreya, R., Fiorino, G., Vetrano, S., Danese, S., Ekici, A. B., Wirtz, S., Thonn, V., Watson, A. J. M., Brakebusch, C., Bergö, M., Neurath, M. F. & Atreya, I., 1 Feb 2016, In: The Journal of Clinical Investigation. 126, 2, p. 611-26 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of TET enzymes in DNA methylation, development, and cancer
Rasmussen, K. D. & Helin, K., 1 Apr 2016, In: Genes & Development. 30, 7, p. 733-50 18 p.Research output: Contribution to journal › Review › peer-review
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Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer
Laugesen, A., Højfeldt, J. W. & Helin, K., Sept 2016, In: Cold Spring Harbor Perspectives in Medicine. 6, 9, a026575.Research output: Contribution to journal › Journal article › Research › peer-review
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SCFCyclin F-dependent degradation of CDC6 suppresses DNA re-replication
Walter, D., Hoffmann, S., Komseli, E-S., Rappsilber, J., Gorgoulis, V. & Sørensen, C. S., 28 Jan 2016, In: Nature Communications. 7, 10 p., 10530.Research output: Contribution to journal › Journal article › Research › peer-review
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SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism
Christensen, L-L., True, K., Hamilton, M. P., Nielsen, M. M., Djodji Damas, N., Damgaard, C. K., Ongen, H., Dermitzakis, E., Bramsen, J. B., Pedersen, J. S., Lund, A. H., Vang, S., Stribolt, K., Madsen, M. R., Laurberg, S., McGuire, S. E., Ørntoft, T. F. & Andersen, C. L., Oct 2016, In: Molecular Oncology. 10, 8Research output: Contribution to journal › Journal article › Research › peer-review
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SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization
Damas, N. D., Marcatti, M., Côme, C., Christensen, L-L., Nielsen, M. M., Baumgartner, R., Gylling, H. M., Maglieri, G., Rundsten, C. F., Seemann, E. S., Rapin, N., Thézenas, S., Vang, S., Ørntoft, T., Andersen, C. L., Pedersen, J. S. & Lund, A. H., 22 Dec 2016, In: Nature Communications. 7, 14 p., 13875.Research output: Contribution to journal › Journal article › Research › peer-review
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Stem cell heterogeneity revealed
Andersen, M. S. & Jensen, K. B., 1 Jun 2016, In: Nature Cell Biology. 18, 6, p. 587-9 3 p.Research output: Contribution to journal › Letter › peer-review
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Structural ECM components in the premetastatic and metastatic niche
Høye, A. M. & Erler, J. T., 1 Jun 2016, In: A J P: Cell Physiology (Online). 310, 11, C955-67.Research output: Contribution to journal › Journal article › Research › peer-review
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Syndecan heparan sulfate proteoglycans: Regulation, signaling and impact on tumor biology
Gomes, A. M., Sinkeviciute, D., Multhaupt, H. A. B., Yoneda, A. & Couchman, J. R., 2016, In: Trends in Glycoscience and Glycotechnology. 28, 163, p. E79-E90Research output: Contribution to journal › Review › peer-review
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Systematic review of survival time in experimental mouse stroke with impact on reliability of infarct estimation
Klarskov, C. K., Klarskov, M. B., Hasseldam, H. & Johansen, F. F., 1 Mar 2016, In: Journal of Neuroscience Methods. 261, p. 10-18 9 p.Research output: Contribution to journal › Review › peer-review
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Systems Level Analysis of Histone H3 Post-translational Modifications (PTMs) Reveals Features of PTM Crosstalk in Chromatin Regulation
Schwämmle, V., Sidoli, S., Ruminowicz, C., Wu, X., Lee, C-F., Helin, K. & Jensen, O. N., Aug 2016, In: Molecular and Cellular Proteomics. 15, 8, p. 2715-29 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180
Engelholm, L. H., Carlsen Melander, E. M., Hald, A., Persson, M., Madsen, D. H., Jürgensen, H. J., Johansson, K., Nielsen, C., Nørregaard, K. S., Ingvarsen, S. Z., Kjaer, A., Trovik, C. S., Lærum, O. D., Bugge, T. H., Eide, J. & Behrendt, N., 1 Jan 2016, In: Journal of Pathology. 238, 1, p. 120-33 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain
Mysling, S., Kristensen, K. K., Larsson, M., Beigneux, A. P., Gårdsvoll, H., Fong, L. G., Bensadouen, A., Jørgensen, T. J. D., Young, S. G. & Ploug, M., 3 Jan 2016, In: eLife. 5, 24 p., e12095.Research output: Contribution to journal › Journal article › Research › peer-review
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The adipose transcriptional response to insulin is determined by obesity, not insulin sensitivity
Rydén, M., Hrydziuszko, O., Mileti, E., Raman, A., Lange, J. B., Boyd, M., Toft, E., Qvist, V., Näslund, E., Thorell, A., Andersson, D. P., Dahlman, I., Gao, H., Sandelin, A. G., Daub, C. O. & Arner, P., 30 Aug 2016, In: Cell Reports. 16, 9, p. 2317-2326 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding
Mysling, S., Kristensen, K. K., Larsson, M., Kovrov, O., Bensadouen, A., Jørgensen, T. J. D., Olivecrona, G., Young, S. G. & Ploug, M., 8 Dec 2016, In: eLife. 5, 18 p., e20958.Research output: Contribution to journal › Journal article › Research › peer-review
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The diplomats
Häfner, S., 1 Oct 2016, In: Microbes and Infection. 18, 10, p. 573-576Research output: Contribution to journal › Journal article › Communication
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The H3K4me3/2 histone demethylase RBR-2 controls axon guidance by repressing the actin-remodeling gene wsp-1
Mariani, L., Lussi, Y. C., Vandamme, J., Riveiro, A. & Salcini, A. E., 1 Mar 2016, In: Development (Cambridge, England). 143, 5, p. 851-63 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The middle ear immune defense changes with age
Nielsen, M. C., Friis, M., Martin-Bertelsen, T., Winther, O., Friis-Hansen, L. J. & Cayé-Thomasen, P., 2016, In: European Archives of Oto-Rhino-Laryngology. 273, 1, p. 81-86 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The multifaceted functions of C/EBPα in normal and malignant haematopoiesis
Ohlsson, E., Schuster, M. B., Hasemann, M. & Porse, B. T., 1 Apr 2016, In: Leukemia. 30, 4, p. 767-75 9 p.Research output: Contribution to journal › Review › peer-review
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The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis
Burkovics, P., Dome, L., Juhasz, S., Altmannova, V., Sebesta, M., Pacesa, M., Fugger, K., Sorensen, C. S., Lee, M. Y. W. T., Haracska, L. & Krejci, L., 20 Jan 2016, In: Nucleic Acids Research. 44, 7, p. 3176-89 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour
Høye, A. M., Couchman, J. R., Wewer, U. M. & Yoneda, A., 24 Jun 2016, In: Scientific Reports. 6, 14 p., 28529.Research output: Contribution to journal › Journal article › Research › peer-review
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The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia
O'Connor, C., Lohan, F., Campos, J., Ohlsson, E., Salomè, M., Forde, C., Artschwager, R., Liskamp, R. M., Cahill, M. R., Kiely, P. A., Porse, B. & Keeshan, K., 6 Oct 2016, In: Oncogene. 35, 40, p. 5272-5281 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Prognostic and Predictive Value of Soluble Type IV Collagen in Colorectal Cancer: A Retrospective Multicenter Study
Rolff, H. C., Christensen, I. J., Vainer, B., Svendsen, L. B., Eefsen, R. L., Wilhelmsen, M., Lund, I. K., Høyer-Hansen, G., Nielsen, H. J., Illemann, M. & Danish Collaborative Research Group on Colorectal Cancer, 15 May 2016, In: Clinical Cancer Research. 22, 10, p. 2427-34 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasis
Gartland, A., Erler, J. T. & Cox, T. R., 1 Sept 2016, In: Journal of Bone Oncology. 5, 3, p. 100-103 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tissue inhibitor of matrix metalloproteinase-1 expression in colorectal cancer liver metastases is associated with vascular structures
Illemann, M., Eefsen, R. H. L., Bird, N. C., Majeed, A., Osterlind, K., Laerum, O. D., Alpizar-Alpizar, W., Lund, I. K. & Høyer-Hansen, G., 1 Feb 2016, In: Molecular Carcinogenesis. 55, 2, p. 193-208 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tissue Inhibitor of Metalloproteinase-1 Is Confined to Tumor-Associated Myofibroblasts and Is Increased With Progression in Gastric Adenocarcinoma
Alpízar-Alpízar, W., Lærum, O. D., Christensen, I. J., Ovrebo, K., Skarstein, A., Høyer-Hansen, G., Ploug, M. & Illemann, M., 1 Aug 2016, In: Journal of Histochemistry and Cytochemistry. 64, 8, p. 483-94 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress
Hoffmann, S., Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, M., Montoya, G., Groth, A., Bekker-Jensen, S. & Mailand, N., 1 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptome analysis of recurrently deregulated genes across multiple cancers identifies new pan-cancer biomarkers
Kaczkowski, B., Tanaka, Y., Kawaji, H., Sandelin, A. G., Andersson, R., Itoh, M., Lassmann, T., the FANTOM5 consortium, Hayashizaki, Y., Carninci, P. & Forrest, A. R. R., 15 Jan 2016, In: Cancer Research. 76, 2, p. 216-226Research output: Contribution to journal › Journal article › Research › peer-review
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UPF2-dependent nonsense-mediated mRNA decay pathway is essential for spermatogenesis by selectively eliminating longer 3'UTR transcripts
Bao, J., Vitting-Seerup, K., Waage, J. E., Tang, C., Ge, Y., Porse, B. T. & Yan, W., May 2016, In: P L o S Genetics. 12, 5, 24 p., e1005863.Research output: Contribution to journal › Journal article › Research › peer-review
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Urokinase receptor cleavage correlates with tumor volume in a transgenic mouse model of breast cancer
Thurison, T., Almholt, K., Gårdsvoll, H., Ploug, M., Høyer-Hansen, G. & Lund, I. K., 1 May 2016, In: Molecular Carcinogenesis.Research output: Contribution to journal › Journal article › Research › peer-review
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Will novel oral formulations change the management of inflammatory bowel disease?
Nielsen, O. H., Seidelin, J. B., Ainsworth, M. A. & Coskun, M., 2 Jun 2016, In: Expert Opinion on Investigational Drugs. 25, 6, p. 709-718 10 p.Research output: Contribution to journal › Review › peer-review
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ZFP57 maintains the parent-of-origin-specific expression of the imprinted genes and differentially affects non-imprinted targets in mouse embryonic stem cells
Riso, V., Cammisa, M., Kukreja, H., Anvar, Z., Verde, G., Sparago, A., Acurzio, B., Lad, S., Lonardo, E., Sankar, A., Helin, K., Feil, R., Fico, A., Angelini, C., Grimaldi, G. & Riccio, A., 30 Sept 2016, In: Nucleic Acids Research. 44, 17, p. 8165-8178 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2015
A cell-based model system links chromothripsis with hyperploidy
Mardin, B. R., Drainas, A. P., Waszak, S. M., Weischenfeldt, J., Isokane, M., Stütz, A. M., Raeder, B., Efthymiopoulos, T., Buccitelli, C., Segura-Wang, M., Northcott, P., Pfister, S. M., Lichter, P., Ellenberg, J. & Korbel, J. O., 1 Sept 2015, In: Molecular Systems Biology. 11, 9, p. 828Research output: Contribution to journal › Journal article › Research › peer-review
75 Citations (Scopus) -
AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival
Rodriguez-Teja, M., Gronau, J. H., Breit, C., Zhang, Y. Z., Minamidate, A., Caley, M. P., McCarthy, A., Cox, T. R., Erler, J. T., Gaughan, L., Darby, S., Robson, C., Mauri, F., Waxman, J. & Sturge, J., 1 Mar 2015, In: Journal of Pathology. 235, 4, p. 581-92 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Allele-Specific DNA Methylation Detection by Pyrosequencing®
Sommer Kristensen, L., Johansen, J. V. & Grønbæk, K., 2015, Pyrosequencing: Methods and Protocols. Lehmann, U. & Tost, J. (eds.). Vol. 1315. p. 271-89 19 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq
Jakobsen, J. S., Bagger, F. O., Hasemann, M. S., Schuster, M. B., Frank, A-K., Waage, J., Vitting-Seerup, K. & Porse, B. T., 5 Feb 2015, In: BMC Genomics. 16, p. 46Research output: Contribution to journal › Journal article › Research › peer-review
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A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment
Nyegaard, M., Rendtorff, N. D., Nielsen, M. S., Corydon, T. J., Demontis, D., Starnawska, A., Hedemand, A., Buniello, A., Niola, F., Overgaard, M. T., Leal, S. M., Ahmad, W., Wikman, F. P., Petersen, K. B., Crueger, D. G., Oostrik, J., Kremer, H., Tommerup, N., Froedin, M., Steel, K. P., & 2 others, 1 Jul 2015, In: P L o S Genetics. 11, 7, p. 1-25 25 p., e1005386.Research output: Contribution to journal › Journal article › Research › peer-review
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A Novel Role for the Zinc-Finger Transcription Factor EGL-46 in the Differentiation of Gas-Sensing Neurons in Caenorhabditis elegans
Rojo Romanos, T., Gramstrup Petersen, J., Redo Riveiro, A. & Pocock, R. D. J., 1 Jan 2015, In: Genetics.Research output: Contribution to journal › Journal article › Research › peer-review
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A role for repressive complexes and H3K9 di-methylation in PRDM5-associated brittle cornea syndrome
Porter, L. F., Galli, G. G., Williamson, S., Selley, J., Knight, D., Elcioglu, N., Aydin, A., Elcioglu, M., Venselaar, H., Lund, A. H., Bonshek, R., Black, G. C. & Manson, F. D., 1 Dec 2015, In: Human Molecular Genetics.Research output: Contribution to journal › Journal article › Research › peer-review
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A unified architecture of transcriptional regulatory elements
Andersson, R., Sandelin, A. G. & Danko, C. G., 1 Aug 2015, In: Trends in Genetics. 31, 8, p. 426-433 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks
Huang, H., Strømme, C. B., Saredi, G., Hödl, M., Strandsby, A., González-Aguilera, C., Chen, S., Groth, A. & Patel, D. J., 7 Aug 2015, In: Nature Structural and Molecular Biology. 22, 8, p. 618-626 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CD1d knockout mice exhibit aggravated contact hypersensitivity responses due to reduced interleukin-10 production predominantly by regulatory B cells
Fjelbye, J., Antvorskov, J. C., Buschard, K., Issazadeh-Navikas, S. & Engkilde, K., 1 Nov 2015, In: Experimental Dermatology Online. 24, 11, p. 853-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells
Schulz, A. M., Stutte, S., Hogl, S., Luckashenak, N., Dudziak, D., Leroy, C., Forné, I., Imhof, A., Müller, S. A., Brakebusch, C. H., Lichtenthaler, S. F. & Brocker, T., 1 Nov 2015, In: Journal of Cell Biology. 211, 3, p. 553-67 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity
Burbage, M., Keppler, S. J., Gasparrini, F., Martínez-Martín, N., Gaya, M., Feest, C., Domart, M-C., Brakebusch, C. H., Collinson, L., Bruckbauer, A. & Batista, F. D., 12 Jan 2015, In: The Journal of Experimental Medicine. 212, 1, p. 53-72Research output: Contribution to journal › Journal article › Research › peer-review
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Cdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development
Elias, B. C., Das, A., Parekh, D. V., Mernaugh, G., Adams, R., Yang, Z., Brakebusch, C., Pozzi, A., Marciano, D. K., Carroll, T. J. & Zent, R., 1 Dec 2015, In: Journal of Cell Science. 128, 23, p. 4293-305 13 p.Research output: Contribution to journal › Journal article › Research › peer-review