Carsten Haagen Nielsen

2019

Lewis and AB0 blood group-phenotypes in periodontitis, cardiovascular disease, obesity and stroke

Enevold, C., Nielsen, C. H., Molbo, D., Lund, R., Bendtzen, K., Fiehn, N-E. & Holmstrup, P., 1 Dec 2019, In: Scientific Reports. 9, 1, 7 p., 6283.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

16 Downloads (Pure)

Oxime Coupling of Active Site Inhibited Factor Seven with a Nonvolatile, Water-Soluble Fluorine-18 Labeled Aldehyde

Jeppesen, T. E., Kristensen, L. K., Nielsen, C. H., Petersen, L. C., Kristensen, J. B., Behrens, C., Madsen, J. & Kjaer, A., 20 Mar 2019, In: Bioconjugate Chemistry. 30, 3, p. 775-784 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

Deshmukh, A. S., Peijs, L., Beaudry, J. L., Jespersen, N. Z., Nielsen, C. H., Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, B., Kjaer, A., Tang-Christensen, M., Sanfridson, A., Garred, P., Privé, G. G., Pedersen, B. K., Gerhart-Hines, Z., & 4 othersNielsen, S., Drucker, D. J., Mann, M. & Scheele, C., 5 Nov 2019, In: Cell Metabolism. 30, 5, p. 963-975.e7 21 p.

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

2018

A blood biomarker for monitoring response to anti-EGFR therapy

Hughes, N. P., Xu, L., Nielsen, C. H., Chang, E., Hori, S. S., Natarajan, A., Lee, S., Kjær, A., Kani, K., Wang, S. X., Mallick, P. & Gambhir, S. S., 2018, In: Cancer Biomarkers. 22, 2, p. 333-344 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S., & 24 othersWang, J., Stohlmann, K., Brandslund, I., Christensen, C., Jørgensen, M. E., Linneberg, A., Pedersen, O., Kiebish, M. A., Qvortrup, K., Han, X., Pedersen, B. K., Jastroch, M., Mandrup, S., Kjær, A., Gygi, S. P., Hansen, T., Gillum, M. P., Grarup, N., Emanuelli, B., Nielsen, S., Scheele, C., Tseng, Y-H., Færgeman, N. J. & Gerhart-Hines, Z., 3 Jul 2018, In: Cell Metabolism. 28, 1, p. 159-174.e11

Research output: Contribution to journal › Journal article › Research › peer-review

43 Citations (Scopus)

187 Downloads (Pure)

Effect of inhibition of CBP-coactivated β-catenin-mediated Wnt signalling in uremic rats with vascular calcifications

Gravesen, E., Nordholm, A., Mace, M., Morevati, M., Høgdall, E., Nielsen, C., Kjær, A., Olgaard, K. & Lewin, E., 2018, In: PLOS ONE. 13, 8, e0201936.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

52 Downloads (Pure)

Exogenous BMP7 in aortae of rats with chronic uremia ameliorates expression of profibrotic genes, but does not reverse established vascular calcification

Gravesen, E., Lerche Mace, M., Nordholm, A., Hofman-Bang, J., Hruska, K., Haagen Nielsen, C., Kjær, A., Olgaard, K. & Lewin, E., Jan 2018, In: PLOS ONE. 13, 1, 18 p., e0190820.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

42 Downloads (Pure)

Site-Specific ⁶⁴Cu Labeling of the Serine Protease, Active Site Inhibited Factor Seven Azide (FVIIai-N₃), Using Copper Free Click Chemistry

Jeppesen, T. E., Kristensen, L. K., Nielsen, C. H., Petersen, L. C., Kristensen, J. B., Behrens, C., Madsen, J. & Kjaer, A., 2018, In: Bioconjugate Chemistry. 29, 1, p. 117-125 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

2017

Neodymium-140 DOTA-LM3: Evaluation of anGenerator for PET with a Non-Internalizing Vector

Severin, G. W., Kristensen, L. K., Nielsen, C. H., Fonslet, J., Jensen, A. I., Frellsen, A. F., Jensen, K. M., Elema, D. R., Maecke, H., Kjær, A., Johnston, K. & Köster, U., 2017, In: Frontiers in Medicine. 4, 9 p., 98.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

48 Downloads (Pure)

Uremia does not affect neointima formation in mice

Aarup, A., Nielsen, C. H., Bisgaard, L. S., Bot, I., El-Ali, H. H., Kjaer, A., Nielsen, L. & Pedersen, T. X., 1 Dec 2017, In: Scientific Reports. 7, 1, 8 p., 6496.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

49 Downloads (Pure)

2016

Hypoxia-Inducible Factor-1α Expression in Macrophages Promotes Development of Atherosclerosis

Pedersen, A. A., Pedersen, T. X., Junker, N., Christoffersen, C., Bartels, E. D., Madsen, M., Nielsen, C. H. & Nielsen, L. B., 1 Sept 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 9, p. 1782-1790 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

54 Citations (Scopus)

PET Imaging of Tissue Factor in Pancreatic Cancer Using 64Cu-Labeled Active Site-Inhibited Factor VII

Nielsen, C. H., Jeppesen, T. E., Kristensen, L. K., Jensen, M. M., El Ali, H. H., Madsen, J., Wiinberg, B., Petersen, L. C. & Kjaer, A., 1 Jul 2016, In: Journal of Nuclear Medicine. 57, 7, p. 1112-1119 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Quantitative PET Imaging of Tissue Factor Expression Using 18F-labled Active Site Inhibited Factor VII

Nielsen, C. H., Erlandsson, M., Jeppesen, T. E., Jensen, M. M., Kristensen, L. K., Madsen, J., Petersen, L. C. & Kjaer, A., 1 Jan 2016, In: The Journal of Nuclear Medicine. 57, 1, p. 89-95 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

2015

[64Cu]-Labelled Trastuzumab: Optimisation of Labelling by DOTA and NODAGA Conjugation and Initial Evaluation in Mice

Schjøth-Eskesen, C., Nielsen, C. H., Heissel, S., Højrup, P., Hansen, P. R., Gillings, N. & Kjær, A., 30 May 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, 6, p. 227-33 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [⁴⁵Ti](salan)Ti(dipic)

Severin, G. W., Nielsen, C. H., Jensen, A. I., Fonslet, J., Kjær, A. & Zhuravlev, F., 24 Sept 2015, In: Journal of Medicinal Chemistry. 58, 18, p. 7591-7595 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

First-in-human uPAR PET: Imaging of Cancer Aggressiveness

Persson, M., Skovgaard, D., Brandt-Larsen, M., Christensen, C., Madsen, J., Nielsen, C. H., Røndbjerg, T. T., Klausen, T. L., Holm, S., Loft, A., Berthelsen, A. K., Ploug, M., Pappot, H., Brasso, K., Kroman, N., Højgaard, L. & Kjaer, A., 2015, In: Theranostics. 5, 12, p. 1303-16 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

61 Citations (Scopus)

In vivo imaging of therapy response to a novel Pan-HER antibody mixture using FDG and FLT positron emission tomography

Nielsen, C. H., Jensen, M. M., Kristensen, L. K., Dahlman, A., Fröhlich, C., Jacobsen, H. J., Poulsen, T. T., Lantto, J., Horak, I. D., Kragh, M. & Kjaer, A., Oct 2015, In: OncoTarget. 6, 35, p. 37486-99 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Synthesis and characterization of ¹⁸F-labeled active site inhibited factor VII (ASIS)

Erlandsson, M., Nielsen, C. H., Jeppesen, T. E., Kristensen, J. B., Petersen, L. C., Madsen, J. & Kjaer, A., 15 May 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, 5, p. 196-201 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

The use of dynamic nuclear polarization ¹³C-pyruvate MRS in cancer

Borgwardt, H. G., Espe Hansen, A., Hjort Johannesen, H., Clemmensen, A. E., Ardenkjær-Larsen, J. H., Haagen Nielsen, C. & Kjær, A., 2015, In: American Journal of Nuclear Medicine and Molecular Imaging. 5, 5, p. 548-560 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2014

18F-FDG and 18F-FLT-PET Imaging for Monitoring Everolimus Effect on Tumor-Growth in Neuroendocrine Tumors: Studies in Human Tumor Xenografts in Mice

Johnbeck, C. B., Munk Jensen, M., Nielsen, C. H., Fisker Hag, A. M., Knigge, U. & Kjaer, A., 13 Mar 2014, In: PLOS ONE. 9, 3, p. 1-8 8 p., e91387.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

A titratable two-step transcriptional amplification strategy for targeted gene therapy based on ligand-induced intramolecular folding of a mutant human estrogen receptor

Chen, I. Y., Paulmurugan, R., Nielsen, C. H., Wang, D. S., Chow, V., Robbins, R. C. & Gambhir, S. S., Apr 2014, In: Molecular Imaging and Biology. 16, 2, p. 224-34 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Evaluation of σ-1 receptor radioligand 18F-FTC-146 in rats and squirrel monkeys using PET

James, M. L., Shen, B., Nielsen, C. H., Behera, D., Buckmaster, C. L., Mesangeau, C., Zavaleta, C., Vuppala, P. K., Jamalapuram, S., Avery, B. A., Lyons, D. M., McCurdy, C. R., Biswal, S., Gambhir, S. S. & Chin, F. T., 1 Jan 2014, In: Journal of Nuclear Medicine. 55, 1, p. 147-53 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

2013

MicroRNA-regulated non-viral vectors with improved tumor specificity in an orthotopic rat model of hepatocellular carcinoma

Ronald, J. A., Katzenberg, R., Nielsen, C. H., Jae, H. J., Hofmann, L. V. & Gambhir, S. S., 30 May 2013, In: Gene Therapy. 20, p. 1006-1013 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Molecular photoacoustic imaging of follicular thyroid carcinoma

Levi, J., Kothapalli, S-R., Bohndiek, S., Yoon, J-K., Dragulescu-Andrasi, A., Nielsen, C. H., Tisma, A., Bodapati, S., Gowrishankar, G., Yan, X., Chan, C., Starcevic, D. & Gambhir, S. S., 15 Mar 2013, In: Clinical Cancer Research. 19, 6, p. 1494-502 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

84 Citations (Scopus)

2012

A New Positron Emission Tomography (PET) Radioligand for Imaging Sigma-1 Receptors in Living Subjects

James, M. L., Shen, B., Zavaleta, C. L., Nielsen, C. H., Mésangeau, C., Vuppala, P. K., Chan, C., Avery, B. A., Fishback, J. A., Matsumoto, R. R., Gambhir, S. S., McCurdy, C. R. & Chin, F. T., 11 Oct 2012, In: Journal of Medicinal Chemistry. 55, 19, p. 8272-8282 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

56 Citations (Scopus)

Positron Emission Tomography of (64)Cu-DOTA-Rituximab in a Transgenic Mouse Model Expressing Human CD20 for Clinical Translation to Image NHL

Natarajan, A., Gowrishankar, G., Nielsen, C. H., Wang, S., Iagaru, A., Goris, M. L. & Gambhir, S. S., Oct 2012, In: Molecular Imaging and Biology. 14, 5, p. 608-616 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis

Tran, P. T., Shroff, E. H., Burns, T. F., Thiyagarajan, S., Das, S. T., Zabuawala, T., Chen, J., Cho, Y-J., Luong, R., Tamayo, P., Salih, T., Aziz, K., Adam, S. J., Vicent, S., Nielsen, C. H., Withofs, N., Sweet-Cordero, A., Gambhir, S. S., Rudin, C. M. & Felsher, D. W., 24 May 2012, In: P L o S Genetics (Online). 8, 5, p. 1-10 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

76 Citations (Scopus)

2011

Preclinical Evaluation of Raman Nanoparticle Biodistribution for their Potential Use in Clinical Endoscopy Imaging

Zavaleta, C. L., Hartman, K. B., Miao, Z., James, M. L., Kempen, P., Thakor, A., Nielsen, C. H., Sinclair, R., Cheng, Z. & Gambhir, S. S., 8 Aug 2011, In: Small. 7, 15, p. 2232-2240

Research output: Contribution to journal › Journal article › Research › peer-review

61 Citations (Scopus)

2010

Indirect imaging of cardiac-specific transgene expression using a bidirectional two-step transcriptional amplification strategy

Chen, I. Y., Gheysens, O., Ray, S., Wang, Q., Padmanabhan, P., Paulmurugan, R., Loening, A. M., Rodriguez-Porcel, M., Willmann, J. K., Sheikh, A. Y., Nielsen, C. H., Hoyt, G., Contag, C. H., Robbins, R. C., Biswal, S., Wu, J. C. & Gambhir, S. S., Jul 2010, In: Gene Therapy (Basingstoke). 17, 7, p. 827-38 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

PET imaging of tumor neovascularization in a transgenic mouse model with a novel 64Cu-DOTA-knottin peptide

Nielsen, C. H., Kimura, R. H., Withofs, N., Tran, P. T., Miao, Z., Cochran, J. R., Cheng, Z., Felsher, D., Kjær, A., Willmann, J. K. & Gambhir, S. S., 15 Nov 2010, In: Cancer Research. 70, 22, p. 9022-30 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

39 Citations (Scopus)

2009

Imaging gene expression in human mesenchymal stem cells: from small to large animals

Willmann, J. K., Paulmurugan, R., Rodriguez-Porcel, M., Stein, W., Brinton, T. J., Connolly, A. J., Nielsen, C. H., Lutz, A. M., Lyons, J., Ikeno, F., Suzuki, Y., Rosenberg, J., Chen, I. Y., Wu, J. C., Yeung, A. C., Yock, P., Robbins, R. C. & Gambhir, S. S., Jul 2009, In: Radiology. 252, 1, p. 117-27 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

72 Citations (Scopus)

Matrix-insensitive protein assays push the limits of biosensors in medicine

Gaster, R. S., Hall, D. A., Nielsen, C. H., Osterfeld, S. J., Yu, H., Mach, K. E., Wilson, R. J., Murmann, B., Liao, J. C., Gambhir, S. S. & Wang, S. X., 2009, In: Nature Medicine. 15, 11, p. 1327-1332 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

291 Citations (Scopus)

2008

Targeted microbubbles for imaging tumor angiogenesis: assessment of whole-body biodistribution with dynamic micro-PET in mice

Willmann, J. K., Cheng, Z., Davis, C., Lutz, A. M., Schipper, M. L., Nielsen, C. H. & Gambhir, S. S., 2008, In: Radiology. 249, 1, p. 212-9 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

136 Citations (Scopus)

Carsten Haagen Nielsen

Research output

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