Imaging gene expression in human mesenchymal stem cells: from small to large animals

Jürgen K Willmann; Ramasamy Paulmurugan; Martin Rodriguez-Porcel; William Stein; Todd J Brinton; Andrew J Connolly; Carsten Haagen Nielsen; Amelie M Lutz; Jennifer Lyons; Fumiaki Ikeno; Yoriyasu Suzuki; Jarrett Rosenberg; Ian Y Chen; Joseph C Wu; Alan C Yeung; Paul Yock; Robert C Robbins; Sanjiv S Gambhir

doi:10.1148/radiol.2513081616

Imaging gene expression in human mesenchymal stem cells: from small to large animals

Jürgen K Willmann, Ramasamy Paulmurugan, Martin Rodriguez-Porcel, William Stein, Todd J Brinton, Andrew J Connolly, Carsten Haagen Nielsen, Amelie M Lutz, Jennifer Lyons, Fumiaki Ikeno, Yoriyasu Suzuki, Jarrett Rosenberg, Ian Y Chen, Joseph C Wu, Alan C Yeung, Paul Yock, Robert C Robbins, Sanjiv S Gambhir

Cluster for Molecular Imaging

72 Citations (Scopus)

Abstract

To evaluate the feasibility of reporter gene imaging in implanted human mesenchymal stem cells (MSCs) in porcine myocardium by using clinical positron emission tomography (PET)-computed tomography (CT) scanning.

Original language	English
Journal	Radiology
Volume	252
Issue number	1
Pages (from-to)	117-27
Number of pages	11
ISSN	0033-8419
DOIs	https://doi.org/10.1148/radiol.2513081616
Publication status	Published - Jul 2009

Keywords

Animals
Cells, Cultured
Female
Gene Expression Profiling
Genes, Reporter
Humans
Mesenchymal Stem Cell Transplantation
Mesenchymal Stem Cells
Positron-Emission Tomography
Proteome
Rats
Rats, Sprague-Dawley

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Willmann, J. K., Paulmurugan, R., Rodriguez-Porcel, M., Stein, W., Brinton, T. J., Connolly, A. J., Nielsen, C. H., Lutz, A. M., Lyons, J., Ikeno, F., Suzuki, Y., Rosenberg, J., Chen, I. Y., Wu, J. C., Yeung, A. C., Yock, P., Robbins, R. C., & Gambhir, S. S. (2009). Imaging gene expression in human mesenchymal stem cells: from small to large animals. Radiology, 252(1), 117-27. https://doi.org/10.1148/radiol.2513081616

Willmann, JK, Paulmurugan, R, Rodriguez-Porcel, M, Stein, W, Brinton, TJ, Connolly, AJ, Nielsen, CH, Lutz, AM, Lyons, J, Ikeno, F, Suzuki, Y, Rosenberg, J, Chen, IY, Wu, JC, Yeung, AC, Yock, P, Robbins, RC & Gambhir, SS 2009, 'Imaging gene expression in human mesenchymal stem cells: from small to large animals', Radiology, vol. 252, no. 1, pp. 117-27. https://doi.org/10.1148/radiol.2513081616

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abstract = "To evaluate the feasibility of reporter gene imaging in implanted human mesenchymal stem cells (MSCs) in porcine myocardium by using clinical positron emission tomography (PET)-computed tomography (CT) scanning.",

keywords = "Animals, Cells, Cultured, Female, Gene Expression Profiling, Genes, Reporter, Humans, Mesenchymal Stem Cell Transplantation, Mesenchymal Stem Cells, Positron-Emission Tomography, Proteome, Rats, Rats, Sprague-Dawley",

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year = "2009",

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doi = "10.1148/radiol.2513081616",

language = "English",

volume = "252",

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AU - Willmann, Jürgen K

AU - Paulmurugan, Ramasamy

AU - Rodriguez-Porcel, Martin

AU - Stein, William

AU - Brinton, Todd J

AU - Connolly, Andrew J

AU - Nielsen, Carsten Haagen

AU - Lutz, Amelie M

AU - Lyons, Jennifer

AU - Ikeno, Fumiaki

AU - Suzuki, Yoriyasu

AU - Rosenberg, Jarrett

AU - Chen, Ian Y

AU - Wu, Joseph C

AU - Yeung, Alan C

AU - Yock, Paul

AU - Robbins, Robert C

AU - Gambhir, Sanjiv S

N1 - (c) RSNA, 2009.

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N2 - To evaluate the feasibility of reporter gene imaging in implanted human mesenchymal stem cells (MSCs) in porcine myocardium by using clinical positron emission tomography (PET)-computed tomography (CT) scanning.

AB - To evaluate the feasibility of reporter gene imaging in implanted human mesenchymal stem cells (MSCs) in porcine myocardium by using clinical positron emission tomography (PET)-computed tomography (CT) scanning.

KW - Animals

KW - Cells, Cultured

KW - Female

KW - Gene Expression Profiling

KW - Genes, Reporter

KW - Humans

KW - Mesenchymal Stem Cell Transplantation

KW - Mesenchymal Stem Cells

KW - Positron-Emission Tomography

KW - Proteome

KW - Rats

KW - Rats, Sprague-Dawley

U2 - 10.1148/radiol.2513081616

DO - 10.1148/radiol.2513081616

M3 - Journal article

C2 - 19366903

SN - 0033-8419

VL - 252

SP - 117

EP - 127

JO - Radiology

JF - Radiology

IS - 1

ER -

Imaging gene expression in human mesenchymal stem cells: from small to large animals

Abstract

Keywords

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