Duc Ninh Nguyen

2019

Gut and immune effects of bioactive milk factors in preterm pigs exposed to prenatal inflammation

Ren, S., Hui, Y., Goericke-Pesch, S., Pankratova, S., Kot, W., Pan, X., Thymann, T., Sangild, P. T. & Nguyen, D. N., Jul 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 317, 1, p. G67-G77

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Heat treatment and irradiation reduce anti-bacterial and immune-modulatory properties of bovine colostrum

Nguyen, D. N., Currie, A. J., Ren, S., Bering, S. B. & Sangild, P. T., 2019, In: Journal of Functional Foods. 57, p. 182-189 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Human Milk Fortification with Bovine Colostrum Is Superior to Formula-Based Fortifiers to Prevent Gut Dysfunction, Necrotizing Enterocolitis, and Systemic Infection in Preterm Pigs

Sun, J., Li, Y., Pan, X., Nguyen, D. N., Brunse, A., Bojesen, A. M., Rudloff, S., Mortensen, M. S., Burrin, D. G. & Sangild, P. T., 1 Feb 2019, In: Journal of Parenteral and Enteral Nutrition. 43, 2, p. 252-262

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Pathogenesis and biomarkers for necrotizing enterocolitis: Getting any closer?

Nguyen, D. N. & Sangild, P. T., Jul 2019, In: EBioMedicine.

Research output: Contribution to journal › Journal article › Communication

3 Citations (Scopus)

Rapid Proteome Changes in Plasma and Cerebrospinal Fluid Following Bacterial Infection in Preterm Newborn Pigs

Muk, T., Stensballe, A., Pankratova, S., Duc Ninh Nguyen, Brunse, A., Sangild, P. T. & Jiang, P-P., 15 Nov 2019, In: Frontiers in Immunology. 10

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Synbiotics Combined with Glutamine Stimulate Brain Development and the Immune System in Preterm Pigs

Andersen, A. D., Nguyen, D. N., Langhorn, L., Renes, I. B., Van Elburg, R. M., Hartog, A., Tims, S., Van De Looij, Y., Sangild, P. T. & Thymann, T., 2019, In: Journal of Nutrition. 149, 1, p. 36-45 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

2018

Bioactive Whey Protein Concentrate and Lactose Stimulate Gut Function in Formula-Fed Preterm Pigs

Li, Y., Nguyen, D. N., Obelitz-Ryom, K., Andersen, A. D., Thymann, T., Chatterton, D. E. W., Purup, S., Heckmann, A. B., Bering, S. B. & Sangild, P. T., 1 Jan 2018, In: Journal of Pediatric Gastroenterology and Nutrition. 66, 1, p. 128-134 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Bovine Milk Oligosaccharides with Sialyllactose for Preterm Piglets

Obelitz-Ryom, K., Rendboe, A. K., Nguyen, D. N., Rudloff, S., Brandt, A. B., Nielsen, D. S., Heckmann, A. B., Chichlowski, M., Sangild, P. T., Thymann, T. & Bering, S. B., 12 Oct 2018, In: Nutrients. 10, 10, p. 1-18 1489.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

66 Downloads (Pure)

Early microbial colonization affects DNA methylation of genes related to intestinal immunity and metabolism in preterm pigs

Pan, X., Gong, D., Nguyen, D. N., Zhang, X., Hu, Q., Lu, H., Fredholm, M., Sangild, P. T. & Gao, F., 1 Jun 2018, In: D N A Research. 25, 3, p. 287–296

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

55 Downloads (Pure)

Neonatal gut and immune maturation is determined more by postnatal age than by postconceptional age in moderately preterm pigs

Ren, S., Hui, Y., Obelitz-Ryom, K., Brandt, A. B., Kot, W., Nielsen, D. S., Thymann, T., Sangild, P. T. & Nguyen, D. N., Nov 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 315, 5, p. G855-G867

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Nutrient Fortification of Human Donor Milk Affects Intestinal Function and Protein Metabolism in Preterm Pigs

Sun, J., Li, Y., Nguyen, D. N., Mortensen, M. S., van den Akker, C. H. P., Skeath, T., Pors, S. E., Pankratova, S., Rudloff, S., Sørensen, S. J., Burrin, D. G., Thymann, T. & Sangild, P. T., 1 Mar 2018, In: Journal of Nutrition. 148, 3, p. 336-347 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Prenatal Intra-Amniotic Endotoxin Induces Fetal Gut and Lung Immune Responses and Postnatal Systemic Inflammation in Preterm Pigs

Nguyen, D. N., Thymann, T., Goericke-Pesch, S. K., Ren, S., Wei, W., Skovgaard, K., Damborg, P., Brunse, A., van Gorp, C., Kramer, B. W., Wolfs, T. G. & Sangild, P. T., 2018, In: American Journal of Pathology. 188, 11, p. 2629-2643 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

2017

Elevated levels of circulating cell-free DNA and neutrophil proteins are associated with neonatal sepsis and necrotizing enterocolitis in immature mice, pigs and infants

Nguyen, D. N., Stensballe, A., Lai, J. C. Y., Jiang, P., Brunse, A., Li, Y., Sun, J., Mallard, C., Skeath, T., Embleton, N. D., Berrington, J. E. & Sangild, P. T., 2017, In: Innate Immunity. 23, 6, p. 524-536 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Human milk oligosaccharide effects on intestinal function and inflammation after preterm birth in pigs

Rasmussen, S. O., Martin, L., Østergaard, M. V., Rudloff, S., Roggenbuck, M., Nguyen, D. N., Sangild, P. T. & Bering, S. B., 1 Feb 2017, In: The Journal of Nutritional Biochemistry. 40, p. 141-154 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs

Li, Y., Nguyen, D. N., de Waard, M., Christensen, L., Zhou, P., Jiang, P., Sun, J., Bojesen, A. M., Lauridsen, C., Lykkesfeldt, J., Dalsgaard, T. K., Bering, S. B. & Sangild, P. T., 1 Jun 2017, In: Journal of Nutrition. 147, 6, p. 1121-1130

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

2016

Bovine lactoferrin regulates cell survival, apoptosis and imflammation in intestinal epithelial cells and preterm pig intestine

Nguyen, D. N., Jiang, P., Stensballe, A., Bendixen, E., Sangild, P. T. & Chatterton, D. E. W., 29 Apr 2016, In: Journal of Proteomics. 139, p. 95-102 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

33 Citations (Scopus)

Delayed development of systemic immunity in preterm pigs as a model for preterm infants

Nguyen, D. N., Jiang, P., Frøkiær, H., Heegaard, P. M. H., Thymann, T. & Sangild, P. T., 10 Nov 2016, In: Scientific Reports. 6, 13 p., 36816 .

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

71 Downloads (Pure)

Enteral but not parenteral antibiotics enhance gut function and prevent necrotizing enterocolitis in formula-fed newborn preterm pigs

Birck, M. M., Nguyen, D. N., Cilieborg, M. S., Bin Shamzir Kamal, S., Nielsen, D. S., Damborg, P. P., Olsen, J. E., Lauridsen, C., Sangild, P. T. & Thymann, T., 1 Mar 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 5, p. G323-G333 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

32 Citations (Scopus)

GUT, IMMUNITY AND BRAIN DEVELOPMENT IS IMMATURE IN PRETERM PIGS AND RESPONSIVE TO DIFFERENT MILK DIETS

Ryom, K., Andersen, A. D., Nguyen, D. N., Bergström, A., Skovgaard, K., Thymann, T., Sangild, P. T. & Bering, S. B., Nov 2016, In: European Journal of Pediatrics. 175, 11, p. 1517-1518 2 p., EAPS-0802.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Impaired postnatal systemic immunity in preterm neonates

Nguyen, D. N., Jiang, P., Frøkiær, H., Thymann, T. & Sangild, P. T., Nov 2016, In: European Journal of Pediatrics. 175, 11, p. 1782 1 p., EAPS-0360.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Oral antibiotics increase blood neutrophil maturation and reduce bacteremia and necrotizing enterocolitis in the immediate postnatal period of preterm pigs

Nguyen, D. N., Fuglsang, E., Jiang, P., Birck, M. M., Pan, X., Bin Shamzir Kamal, S., Pors, S. E., Gammelgaard, P. L., Nielsen, D. S., Thymann, T., Levy, O., Frøkiær, H. & Sangild, P. T., 1 Jan 2016, In: Innate Immunity. 22, 1, p. 51-62 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Processing of whey modulates proliferative and immune functions in intestinal epithelial cells

Nguyen, D. N., Sangild, P. T., Li, Y., Bering, S. B. & Chatterton, D. E. W., 1 Feb 2016, In: Journal of Dairy Science. 99, 2, p. 959-969 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

2015

Protective effects of transforming growth factor β2 in intestinal epithelial cells by regulation of proteins associated with stress and endotoxin responses

Nguyen, D. N., Jiang, P., Jacobsen, S., Sangild, P. T., Bendixen, E. & Chatterton, D. E. W., 10 Feb 2015, In: P L o S One. 10, 2, 18 p., e0117608.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

1134 Downloads (Pure)

2014

Bioactivity of Minor Milk Components: Protective Effects against Intestinal Inflammation and Necrotizing Enterocolitis in Cell and Preterm Pig Models

Nguyen, D. N., 2014, Department of Food Science, Faculty of Science, University of Copenhagen. 212 p.

Research output: Book/Report › Ph.D. thesis

Effects of bovine lactoferrin on the immature porcine intestine

Nguyen, D. N., Li, Y., Sangild, P. T., Bering, S. B. & Chatterton, D. E. W., 28 Jan 2014, In: British Journal of Nutrition. 111, 2, p. 321-331 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

Transforming growth factor-β2 and endotoxin interact to regulate homeostasis via interleukin-8 levels in the immature intestine.

Nguyen, D. N., Sangild, P. T., Østergaard, M. V., Bering, S. B. & Chatterton, D. E. W., 1 Oct 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 307, 7, p. G689-G699 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

2013

Anti-inflammatory mechanisms of bioactive milk proteins in the intestine of newborns

Chatterton, D. E. W., Nguyen, D. N., Bering, S. B. & Sangild, P. T., 2013, In: International Journal of Biochemistry & Cell Biology. 45, 8, p. 1730-1747 18 p.

Research output: Contribution to journal › Review › peer-review

205 Citations (Scopus)

Lactoferrin-enriched formula modulates necrotising enterocolitis and intestinal inflammation in preterm pigs

Nguyen, D. N., Li, Y., Sangild, P. T., Bering, S. B. & Chatterton, D. E. W., 2013, In: Journal of Pediatric Gastroenterology and Nutrition. 56, Supplement 2, p. 161 1 p., PD-N-0118.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

15 Citations (Scopus)

2012

Transforming growth factor beta 2 (TGF-ß2) effects on lipopolysaccharide (LPS)-induces cytokine secretion in developing intestianl epithelial cells Pslc1

Nguyen, D. N., Østergaard, M. V., Sangild, P. T., Bering, S. B. & Chatterton, D. E. W., 2012, In: Regulatory Peptides. 177, Suppl., p. S29 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research

Duc Ninh Nguyen

Research output

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