Research output per year
Research output per year
Research activity per year
Academic Degrees:
2002: Degree of Ph.D. Dept. of Molecular Biology, Protein Chemistry Laboratory, University of Aarhus, Denmark & jointly at Dept. of Nutrition, UC Davis California
1990: Degree of Master of Science (Biostructural Chemistry). University of Aarhus, Denmark.
1985: Degree of Batchelor of Science, University of Dundee, Scotland, Biochemistry
1982: Fellowship of the Institute of Medical Laboratory Sciences, 1982 Bristol Polytechnic, UK
1979: Higher National Diploma in Medical Laboratory Sciences, 1979. Bristol Polytechnic, UK
Academic Employment:
2016: Associate Professor, Bioactivity of Milk Proteins and Peptides (Tenure), ongoing
2015: Associate Professor of Dairy Biochemistry and Technology, FOOD and also Section of Comparative Paediatrics and Nutrition, Faculty of Health and Medical Sciences, University of Copenhagen
2014: Associate Professor of Dairy Biochemistry and Technology, FOOD, Faculty of Science andalso Department of Human Nutrition, Exercise and Sports, section of Clinical and Experimental Nutrition, University of Copenhagen
2009: Associate Professor of Dairy Biochemistry and Technology, FOOD, Faculty of Science, University of Copenhagen
2007: Senior Postdoctoral Research Fellow, Dublin Oxford Glycobiology Lab, UC Dublin
2006: Biochemist, Oligosaccharide Research Lab, Moorepark Food Research Centre, Ireland
2002-2006: Visiting researcher, (Post.doc), Dept. of Molecular Biology, Protein Chemistry Laboratory, University of Aarhus, Denmark
1995-2006: Biochemist, Arla Foods Innovation, Denmark
2000: Staff Research Associate, Dept. of Nutrition, University of California Davis
1998: Visiting Researcher, Dept. of Nutrition, University of California Davis
1995: Biochemist, R&D Laboratory MD Foods Ingredients, Denmark
1991: Biochemist, R&D Laboratory Danmark Protein, Denmark
1991: Clinical Research Assistant, Institute of Experimental Clinical Research, University of Aarhus
Research Leadership:
Selected Publications:
~30 publications in international journals, including 3 US patents, 3 book chapters
Sun, J., Pan, X., Christiansen, L.I., Yuan, X.L., Skovgaard, K., Chatterton, D.E.W., Kaalund, S.S., Gao, F., Sangild, P.T., Pankratova, S.: (2018) Necrotizing enterocolitis is associated with acute brain responses in preterm pigs. J. Neuroinflammation 15(1): 180-
Li, Y., Nguyen, D.N., Obelitz-Ryom, K., Andersen, A.D., Thymann, T., Chatterton, D.E.W., Purup, S., Heckmann, A.B., Bering, S.B. & Sangild, P.T.: (2018) Bioactive whey protein concentrate and lactose stimulate gut function in formula-fed preterm pigs. J Pediatr Gastroenterol Nutr 66(1):128-134
NGUYEN, D.N., JIANG, P., STENSBALLE, A., BENDIXEN, E., SANGILD, P.T. & CHATTERTON, D.E.: (2016) Bovine lactoferrin regulates cell survival, apoptosis and inflammation in intestinal epithelial cells and preterm pig intestine. J Proteomics 139:95-102
Støy, A.C., Sangild, P.T., Skovgaard, K., Thymann, T., Bjerre, M., Chatterton, D.E., Purup, S., Boye, M., Heegaard, P.M.: (2016) Spray-dried, pasteurised bovine colostrum protects against gut dysfunction and inflammation in preterm pigs. J. Pediatr Gastroenterol Nutr 63(2):280-287
NGUYEN, D.N., SANGILD, P.T., Li, Y., BERING, S.B. & CHATTERTON, D.E. (2016) Processing of whey modulates proliferative and immune functions in intestinal epithelial cells. J Dairy Sci 99(2):959-969
NGUYEN, D.N., JIANG, P., JACOBSEN, S., SANGILD, P.T., BENDIXEN, E., & CHATTERTON, D.E.: (2015)
Protective effects of transforming growth factor β2 in intestinal cells by regulation of proteins associated with stress and endotoxin responses. PloS One 10(2):e0117608
JENSEN, H.B., PEDERSEN, K.S., JOHANSEN, L.B., POULSEN, N.A., BAKMAN, M, CHATTERTON, D.E. & LARSEN, L.B.: (2015) Genetic variation and posttranslational modification of bovine κ-casein: effects on caseino-macropeptide release during renneting J Dairy Sci 98(2): 747-758
NGUYEN, D.N., SANGILD, P.T., OSTERGAARD, M.V., BERING, S.B. & CHATTERTON, D.E.: (2014) Tranforming growth factor-β2 and endotoxin interact to regulate homeostasis via interleukin-8 levels in the immature intestine. Am J Physiol Gastrointest Liver Physiol 307(7):G689-99
LI, Y., JENSEN, M.L., CHATTERTON, D.E.W., JENSEN, B.B., THYMANN, T., KVISTGAARD, A.S. & SANGILD, P.T.: (2014) Raw bovine milk improves gut responses to feeding relative infant formula in preterm piglets. Am J Physiol Gastrointest Liver Physiol 306(1):G81-G90
NGUYEN, D.N., Li, Y., SANGILD, P.T., BERING, S.B. & CHATTERTON, D.E.W.: (2014) Effects of bovine lactoferrin on the immature porcine intestine Br. J. Nutr 111(2): 321-331
LI, Y., OSTERGAARD, M.V., JIANG, P., CHATTERTON, D.E., THYMANN, T., KVISTGAARD, A.S. & SANGILD, P.T.: (2013) Whey protein processing influences formula-induced gut maturation in preterm pigs. J. Nutr 143(12):1934-1942
CHATTERTON, D.E.W., NGUYEN, D.N., BERING, S.B., SANGILD, P.T.: (2013) Anti-inflammatory mechanisms of bioactive milk proteins in the newborn intestine. Int J Biochem Cell Biol 45(8):1730-1747
STØY, A.C., SANGILD, P., SKOVGAARD, K., THYMANN, T., BJERRE, M., CHATTERTON, D., PURUP, S., BOYE, M., SCHMIDT, M., HEEGAARD, P.: (2013) Mild heat treatment does not reduce the colitis-protective effects of bovine colostrum in preterm pigs. J Pediatr Gastroenterol Nutr 56, Supplement 2, 401
LI, Y., THOMAS, T., KVISTGAARD, A.S., CHATTERTON, D:E:W., & SANGILD, P:T.: (2013) Heat treatment of milk reduces intestinal function and resistance to necrotizing enterocolitis in preterm pigs J Pediatr Gastroenterol Nutr 56, Supplement 2, 440
NGUYEN, D.N., LI, Y., SANGILD, P.T., BERING, S.B. & CHATTERTON, D.E.W.: (2013) Lactoferrin-enriched formula modulates necrotizing enterocolitis and intestinal inflammation in preterm pigs J Pediatr Gastroenterol Nutr 56, Supplement 2, 161
NGUYEN, D.N., OSTERGAARD, M.V., SANGILD, P.T., BERING, S.B. & CHATTERTON, D.: (2012) Transforming growth factor beta 2 (TGF-beta 2) effects on lipopolysaccharide (LPS)-induced cytokine secretion in developing intestinal epithelial cells PsIc1. Regulatory Peptides 177(1):S29-S29
(2010) PERSSON, B.A., LUND, M., FORSMAN, J., CHATTERTON, D.E.W., & ÅKESSON, T.:
Molecular evidence of stereo-specific lactoferrin dimers in solution. Biophys Chem 151(3): 187-189
(2010) Ercan, A., CUI, J. CHATTERTON, D.E.W., DEANE, K.D., HAZEN, M.M., BRINTNELL, W., O´DONNELL, C.I., DERBER, L.A., WEINBLATT, M.E., SHADICK, N.A., BELL, D.A., CAIRNS, E., SOLOMON, D.H., HOLERS, V.M., RUDD, P.M., & LEE, D,M.: IgG galactosylation aberrancy precedes disease onset, correlates with disease activity and is prevalent in autoantibodies in rheumatoid arthritis. Arthritis & Rheum, 62 (8), 2239-2248
(2006) CHATTERTON, D.E.W., SMITHERS, G., ROUPAS, P. & BRODKORB, A.: Bioactivity of β-Lactoglobulin and α-Lactalbumin – Technological Implications for Processing. International Dairy Journal, 16 (11) 1229-1240.
(2004) CHATTERTON, D.E.W., RASMUSSEN, J.T., HEEGAARD, C.W., SØRENSEN, E.S. & PETERSEN, T.E.: In vitro digestion of novel milk protein ingredients for use in infant formulas: Identification of new biological functions. Trends in Food Science & Technology, 15 (7-8): 373-383.
(2003): BRÜCK, W.M., KELLEHER, S.L, GIBSON, G.R., NIELSEN, K.E., CHATTERTON, D.E.W. & LŌNNERDAL, B.: rRNA probes used to quantify the effects of glycomacropeptide and α-lactalbumin supplementation on the predominant groups of intestinal bacteria of infant rhesus monkeys challenged with enteropathogenic Escherichia coli. J Pediatr Gastroenterol Nutr, 37 (3): 273-280.
(2003): KELLEHER, S.L., CHATTERTON, D., NIELSEN, K. & LŌNNERDAL, B.: Glycomacropeptide and α-lactalbumin supplementation of infant formula affects growth and nutritional status in infant rhesus monkeys. Am J Clin Nutr, 77:1261-1268.
Responsible for graduate and post-graduate teaching of students in wide topics related to the effects of Milk Processing, such as pasteurization and thermal processes, such as spray-drying on milk proteins and peptides and their functions with a focus on bioactive ingredients. Research focus on the effects of digestion of processed milk protein and peptide ingredients, including minor bioactive factors for infant nutrition and has used models to study this (Rhesus monkey, cell culture and more recently piglet studies). Also the interaction and modulatory effects of milk proteins with each other is a research topic, such as in aggregation reactions and the effects of heat-treatments on the bioactivity of milk proteins. Extensive utilization of purification and protein chemistry techniques, including mass spectrometry, proteomics and glycobiology.
Present projects include:
Teaching:
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Dereck Edward Winston Chatterton (Lecturer)
Activity: Talk or presentation types › Lecture and oral contribution
Dereck Edward Winston Chatterton (Lecturer)
Activity: Talk or presentation types › Lecture and oral contribution
Dereck Edward Winston Chatterton (Lecturer)
Activity: Talk or presentation types › Lecture and oral contribution
Dereck Edward Winston Chatterton (Lecturer)
Activity: Talk or presentation types › Lecture and oral contribution
Dereck Edward Winston Chatterton (Lecturer)
Activity: Talk or presentation types › Lecture and oral contribution
Dereck Edward Winston Chatterton (Lecturer)
Activity: Talk or presentation types › Lecture and oral contribution
Dereck Edward Winston Chatterton (Lecturer)
Activity: Talk or presentation types › Lecture and oral contribution
Dereck Edward Winston Chatterton (Lecturer)
Activity: Talk or presentation types › Lecture and oral contribution