Research output per year
Research output per year
Search results
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2010
p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC
Christoffersen, N. R., Shalgi, R., Frankel, L. B., Leucci, E., Lees, M., Klausen, M., Pilpel, Y., Nielsen, F. C., Oren, M. & Lund, A. H., Feb 2010, In: Cell Death and Differentiation. 17, 2, p. 236-45 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2009
A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites
Uren, A. G., Mikkers, H., Kool, J., van der Weyden, L., Lund, A. H., Wilson, C. H., Rance, R., Jonkers, J., van Lohuizen, M., Berns, A. & Adams, D. J., 2009, In: Nature Protocols (Print Edition). 4, 5, p. 789-98 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Experimental identification of microRNA targets
Ørom, U. A. & Lund, A. H., 2009, In: Gene. 451, 1-2, p. 1-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2008
MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation.
Ørom, U. A., Nielsen, F. C. & Lund, A. H., 2008, In: Molecular Cell. 30, 4, p. 460-71 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells.
Frankel, L., Christoffersen, N. R., Jacobsen, A., Lindow, M., Krogh, A. & Lund, A. H., 2008, In: Journal of Biological Chemistry. 283, 2, p. 1026-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2007
Chromatin-modifying proteins in cancer.
Fog, C. K., Jensen, K. T. & Lund, A. H., 2007, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 115, 10, p. 1060-89 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus.
Sørensen, A. B., Lund, A. H., Kunder, S., Quintanilla-Martinez, L., Schmidt, J., Wang, B., Wabl, M. & Pedersen, F. S., 2007, In: Retrovirology. 4, p. 46Research output: Contribution to journal › Journal article › Research › peer-review
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Isolation of microRNA targets using biotinylated synthetic microRNAs.
Ørom, U. A. & Lund, A. H., 2007, In: Methods. 43, 2, p. 162-5 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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miR-200b mediates post-transcriptional repression of ZFHX1B.
Christoffersen, N. R., Silahtaroglu, A., Ørom, U. L. A., Kauppinen, M. S. & Lund, A. H., 2007, In: RNA: A publication of the RNA Society. 13, 8, p. 1172-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RNA-binding protein Dnd1 inhibits microRNA access to target mRNA.
Kedde, M., Strasser, M. J., Boldajipour, B., Vrielink, J. A. F. O., Slanchev, K., le Sage, C., Nagel, R., Voorhoeve, P. M., van Duijse, J., Ørom, U. A., Lund, A. H., Perrakis, A., Raz, E. & Agami, R., 2007, In: Cell. 131, 7, p. 1273-86 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2006
LNA-modified oligonucleotides mediate specific inhibition of microRNA function.
Ørom, U. A., Kauppinen, S. & Lund, A. H., 2006, In: Gene. 372, p. 137-41 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2005
Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase.
Hernández-Muñoz, I., Lund, A. H., van der Stoop, P., Boutsma, E., Muijrers, I., Verhoeven, E., Nusinow, D. A., Panning, B., Marahrens, Y. & van Lohuizen, M., 2005, In: Proceedings of the National Academy of Science of the United States of America. 102, 21, p. 7635-40 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2004
Emerging roles of Polycomb silencing in X-inactivation and stem cell maintenance.
Muyrers-Chen, I., Hernández-Muñoz, I., Lund, A. H., Valk-Lingbeek, M. E., van der Stoop, P., Boutsma, E., Tolhuis, B., Bruggeman, S. W. M., Taghavi, P., Verhoeven, E., Hulsman, D., Noback, S., Tanger, E., Theunissen, H. & van Lohuizen, M., 2004, In: Cold Spring Harbor Symposia on Quantitative Biology. 69, p. 319-26 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Epigenetics and cancer.
Lund, A. H. & van Lohuizen, M., 2004, In: Genes & Development. 18, 19, p. 2315-35 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polycomb complexes and silencing mechanisms.
Lund, A. H. & van Lohuizen, M., 2004, In: Current Opinion in Cell Biology. 16, 3, p. 239-46 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2002
Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice.
Lund, A. H., Turner, G., Trubetskoy, A., Verhoeven, E., Wientjens, E., Hulsman, D., Russell, R., DePinho, R. A., Lenz, J. & van Lohuizen, M., 2002, In: Nature Genetics. 32, 1, p. 160-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RUNX: a trilogy of cancer genes.
Lund, A. H. & van Lohuizen, M., 2002, In: Cancer Cell. 1, 3, p. 213-5 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
114 Citations (Scopus) -
Target-cell-derived tRNA-like primers for reverse transcription support retroviral infection at low efficiency.
Schmitz, A., Lund, A. H., Hansen, A. C., Duch, M. & Pedersen, F. S., 2002, In: Virology. 297, 1, p. 68-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
2001
Transfer of primer binding site-mutated simian immunodeficiency virus vectors by genetically engineered artificial and hybrid tRNA-like primers.
Hansen, A. C., Grunwald, T., Lund, A. H., Schmitz, A., Duch, M., Uberla, K. & Pedersen, F. S., 2001, In: Journal of Virology. 75, 10, p. 4922-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2000
Alleviation of murine leukemia virus repression in embryonic carcinoma cells by genetically engineered primer binding sites and artificial tRNA primers
Modin, C., Lund, A. H., Schmitz, A., Duch, M. R. & Pedersen, F. S., 20 Dec 2000, In: Virology. 278, 2, p. 368-79 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of a novel human tRNA(Ser(CGA)) functional in murine leukemia virus replication.
Lund, A. H., Schmitz, A., Pedersen, F. S. & Duch, M., 2000, In: BBA General Subjects. 1492, 1, p. 264-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus) -
Mutations of the kissing-loop dimerization sequence influence the site specificity of murine leukemia virus recombination in vivo.
Mikkelsen, J. G., Lund, A. H., Duch, M. & Pedersen, F. S., 2000, In: Journal of Virology. 74, 2, p. 600-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
30 Citations (Scopus) -
Selection of functional tRNA primers and primer binding site sequences from a retroviral combinatorial library: identification of new functional tRNA primers in murine leukemia virus replication.
Lund, A. H., Duch, M. & Pedersen, F. S., 2000, In: Nucleic Acids Research. 28, 3, p. 791-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus) -
Sint1, a common integration site in SL3-3-induced T-cell lymphomas, harbors a putative proto-oncogene with homology to the septin gene family.
Sørensen, A. B., Lund, A. H., Ethelberg, S., Copeland, N. G., Jenkins, N. A. & Pedersen, F. S., 2000, In: Journal of Virology. 74, 5, p. 2161-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
35 Citations (Scopus) -
Sustained systemic delivery of monoclonal antibodies by genetically modified skin fibroblasts.
Noël, D., Pelegrin, M., Brockly, F., Lund, A. H. & Piechaczyk, M., 2000, In: Journal of Investigative Dermatology. 115, 4, p. 740-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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1999
Forced recombination of psi-modified murine leukaemia virus-based vectors with murine leukaemia-like and VL30 murine endogenous retroviruses.
Mikkelsen, J. G., Lund, A. H., Duch, M. & Pedersen, F. S., 1999, In: Journal of General Virology. 80 ( Pt 11), p. 2957-67 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
Replication and pathogenicity of primer binding site mutants of SL3-3 murine leukemia viruses.
Lund, A. H., Schmidt, J., Luz, A., Sørensen, A. B., Duch, M. & Pedersen, F. S., 1999, In: Journal of Virology. 73, 7, p. 6117-22 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
13 Citations (Scopus) -
The kissing-loop motif is a preferred site of 5' leader recombination during replication of SL3-3 murine leukemia viruses in mice.
Lund, A. H., Mikkelsen, J. G., Schmidt, J., Duch, M. & Pedersen, F. S., 1999, In: Journal of Virology. 73, 11, p. 9614-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
21 Citations (Scopus) -
The nucleotide sequence of the high-leukemogenic murine retrovirus SL3-3 reveals a patch of mink cell focus forming-like sequences upstream of the ecotropic envelope gene. Brief report.
Lund, A. H. & Pedersen, F. S., 1999, In: Archives of Virology. 144, 11, p. 2207-12 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
3 Citations (Scopus) -
1998
Extended minus-strand DNA as template for R-U5-mediated second-strand transfer in recombinational rescue of primer binding site-modified retroviral vectors.
Mikkelsen, J. G., Lund, A. H., Dybkaer, K., Duch, M. & Pedersen, F. S., 1998, In: Journal of Virology. 72, 3, p. 2519-25 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
14 Citations (Scopus) -
Recombination in the 5' leader of murine leukemia virus is accurate and influenced by sequence identity with a strong bias toward the kissing-loop dimerization region.
Mikkelsen, J. G., Lund, A. H., Duch, M. & Pedersen, F. S., 1998, In: Journal of Virology. 72, 9, p. 6967-78 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
34 Citations (Scopus) -
1997
Complementation of a primer binding site-impaired murine leukemia virus-derived retroviral vector by a genetically engineered tRNA-like primer.
Lund, A. H., Duch, M., Lovmand, J., Jørgensen, P. & Pedersen, F. S., 1997, In: Journal of Virology. 71, 2, p. 1191-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
33 Citations (Scopus) -
1996
A preferred region for recombinational patch repair in the 5' untranslated region of primer binding site-impaired murine leukemia virus vectors.
Mikkelsen, J. G., Lund, A. H., Kristensen, K. D., Duch, M., Sørensen, M. S., Jørgensen, P. & Pedersen, F. S., 1996, In: Journal of Virology. 70, 3, p. 1439-47 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
45 Citations (Scopus) -
Increased cloning efficiency by temperature-cycle ligation.
Lund, A. H., Duch, M. & Pedersen, F. S., 1996, In: Nucleic Acids Research. 24, 4, p. 800-1 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
57 Citations (Scopus) -
Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein.
Jacobsen, L., Madsen, P., Moestrup, S. K., Lund, A. H., Tommerup, N., Nykjaer, A., Sottrup-Jensen, L., Gliemann, J. & Petersen, C. M., 1996, In: Journal of Biological Chemistry. 271, 49, p. 31379-83 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
205 Citations (Scopus) -
Transcriptional Silencing of Retroviral Vectors.
Lund, A. H., Duch, M. & Pedersen, F. S., 1996, In: Journal of Biomedical Science. 3, 6, p. 365-378 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
33 Citations (Scopus) -
1993
Mutated primer binding sites interacting with different tRNAs allow efficient murine leukemia virus replication.
Lund, A. H., Duch, M., Lovmand, J., Jørgensen, P. & Pedersen, F. S., 1993, In: Journal of Virology. 67, 12, p. 7125-30 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
47 Citations (Scopus)