Anders H. Lund

Publikation

Publikationer pr. år 1993 2000 2007 2010 2011 2012 2013 2014 2015 2016 2019

• 79 Tidsskriftartikel
• 6 Review
• 1 Konferenceabstrakt i tidsskrift
• 1 Leder

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2010

  p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC

  Christoffersen, N. R., Shalgi, R., Frankel, L. B., Leucci, E., Lees, M., Klausen, M., Pilpel, Y., Nielsen, F. C., Oren, M. & Lund, A. H., feb. 2010, I: Cell Death and Differentiation. 17, 2, s. 236-45 10 s.

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  • Oncogenes 100%
  • Up-Regulation 75%
  • MicroRNAs 66%
  • Proto-Oncogenes 30%
  • Cellular Senescence 28%
  285 Citationer (Scopus)
• 2009

  A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites

  Uren, A. G., Mikkers, H., Kool, J., van der Weyden, L., Lund, A. H., Wilson, C. H., Rance, R., Jonkers, J., van Lohuizen, M., Berns, A. & Adams, D. J., 2009, I: Nature Protocols (Print Edition). 4, 5, s. 789-98 9 s.

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  • Mutagen 100%
  • Plate Like Crystal 63%
  • Polymerase Chain Reaction 47%
  • Murine Leukemia Viruses 21%
  • Mutagens 19%
  117 Citationer (Scopus)

• Experimental identification of microRNA targets

  Ørom, U. A. & Lund, A. H., 2009, I: Gene. 451, 1-2, s. 1-5 4 s.

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  • MicroRNAs 100%
  • 3' Untranslated Regions 20%
  • Base Pairing 20%
  • Animals 19%
  • RNA 13%
  72 Citationer (Scopus)
• 2008

  MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation.

  Ørom, U. A., Nielsen, F. C. & Lund, A. H., 2008, I: Molecular Cell. 30, 4, s. 460-71 11 s.

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  • Ribosomal Proteins 100%
  • 5' Untranslated Regions 92%
  • MicroRNAs 67%
  • Messenger RNA 45%
  • Protein Biosynthesis 43%
  933 Citationer (Scopus)

• Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells.

  Frankel, L., Christoffersen, N. R., Jacobsen, A., Lindow, M., Krogh, A. & Lund, A. H., 2008, I: Journal of Biological Chemistry. 283, 2, s. 1026-33 7 s.

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  • Tumor Suppressor Protein 100%
  • MicroRNA 77%
  • Cell Death 67%
  • MicroRNAs 53%
  • Breast Neoplasms 40%
  929 Citationer (Scopus)
• 2007

  Chromatin-modifying proteins in cancer.

  Fog, C. K., Jensen, K. T. & Lund, A. H., 2007, I: Acta Pathologica Microbiologica et Immunologica Scandinavica. 115, 10, s. 1060-89 29 s.

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  • Chromatin 100%
  • Epigenomics 65%
  • Proteins 41%
  • Neoplasms 36%
  • Fungi 33%
  31 Citationer (Scopus)

• Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus.

  Sørensen, A. B., Lund, A. H., Kunder, S., Quintanilla-Martinez, L., Schmidt, J., Wang, B., Wabl, M. & Pedersen, F. S., 2007, I: Retrovirology. 4, s. 46

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  • Murine Leukemia Viruses 100%
  • RNA Splice Sites 95%
  • Exons 63%
  • Gammaretrovirus 40%
  • Mutation 21%
  6 Citationer (Scopus)

• Isolation of microRNA targets using biotinylated synthetic microRNAs.

  Ørom, U. A. & Lund, A. H., 2007, I: Methods. 43, 2, s. 162-5 3 s.

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  124 Citationer (Scopus)

• miR-200b mediates post-transcriptional repression of ZFHX1B.

  Christoffersen, N. R., Silahtaroglu, A., Ørom, U. L. A., Kauppinen, M. S. & Lund, A. H., 2007, I: RNA: A publication of the RNA Society. 13, 8, s. 1172-8 6 s.

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  • Mouse Mirn200 microRNA 100%
  • Cadherins 90%
  • 3' Untranslated Regions 46%
  • Epithelial-Mesenchymal Transition 46%
  • Transforming Growth Factor beta 40%
  143 Citationer (Scopus)

• RNA-binding protein Dnd1 inhibits microRNA access to target mRNA.

  Kedde, M., Strasser, M. J., Boldajipour, B., Vrielink, J. A. F. O., Slanchev, K., le Sage, C., Nagel, R., Voorhoeve, P. M., van Duijse, J., Ørom, U. A., Lund, A. H., Perrakis, A., Raz, E. & Agami, R., 2007, I: Cell. 131, 7, s. 1273-86 13 s.

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  531 Citationer (Scopus)
• 2006

  LNA-modified oligonucleotides mediate specific inhibition of microRNA function.

  Ørom, U. A., Kauppinen, S. & Lund, A. H., 2006, I: Gene. 372, s. 137-41 4 s.

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  • Oligonucleotides 100%
  • MicroRNAs 80%
  • Antisense Oligonucleotides 13%
  • Untranslated RNA 13%
  • Drosophila melanogaster 13%
  313 Citationer (Scopus)
• 2005

  Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase.

  Hernández-Muñoz, I., Lund, A. H., van der Stoop, P., Boutsma, E., Muijrers, I., Verhoeven, E., Nusinow, D. A., Panning, B., Marahrens, Y. & van Lohuizen, M., 2005, I: Proceedings of the National Academy of Science of the United States of America. 102, 21, s. 7635-40 5 s.

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  • X Chromosome Inactivation 100%
  • Ubiquitin-Protein Ligases 87%
  • X Chromosome 86%
  • Histones 71%
  • DNA Methylation 50%
  233 Citationer (Scopus)
• 2004

  Emerging roles of Polycomb silencing in X-inactivation and stem cell maintenance.

  Muyrers-Chen, I., Hernández-Muñoz, I., Lund, A. H., Valk-Lingbeek, M. E., van der Stoop, P., Boutsma, E., Tolhuis, B., Bruggeman, S. W. M., Taghavi, P., Verhoeven, E., Hulsman, D., Noback, S., Tanger, E., Theunissen, H. & van Lohuizen, M., 2004, I: Cold Spring Harbor Symposia on Quantitative Biology. 69, s. 319-26 7 s.

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  11 Citationer (Scopus)

• Epigenetics and cancer.

  Lund, A. H. & van Lohuizen, M., 2004, I: Genes & Development. 18, 19, s. 2315-35 20 s.

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  • Epigenomics 100%
  • Immunologic Monitoring 49%
  • Nucleosomes 44%
  • Cell Cycle Checkpoints 37%
  • Neoplasms 36%
  395 Citationer (Scopus)

• Polycomb complexes and silencing mechanisms.

  Lund, A. H. & van Lohuizen, M., 2004, I: Current Opinion in Cell Biology. 16, 3, s. 239-46 7 s.

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  • Polycomb-Group Proteins 100%
  • RNA Interference 64%
  • Histones 62%
  • Methylation 60%
  • Epigenomics 58%
  244 Citationer (Scopus)
• 2002

  Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice.

  Lund, A. H., Turner, G., Trubetskoy, A., Verhoeven, E., Wientjens, E., Hulsman, D., Russell, R., DePinho, R. A., Lenz, J. & van Lohuizen, M., 2002, I: Nature Genetics. 32, 1, s. 160-5 5 s.

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  • Insertional Mutagenesis 100%
  • Genome 69%
  • Genes 41%
  • Neoplasms 32%
  • Moloney murine leukemia virus 23%
  190 Citationer (Scopus)

• RUNX: a trilogy of cancer genes.

  Lund, A. H. & van Lohuizen, M., 2002, I: Cancer Cell. 1, 3, s. 213-5 2 s.

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  • Neoplasm Genes 100%
  • Stomach Neoplasms 39%
  • Carcinogenesis 35%
  • Transcription Factors 34%
  • Neoplasms 29%
  114 Citationer (Scopus)

• Target-cell-derived tRNA-like primers for reverse transcription support retroviral infection at low efficiency.

  Schmitz, A., Lund, A. H., Hansen, A. C., Duch, M. & Pedersen, F. S., 2002, I: Virology. 297, 1, s. 68-77 9 s.

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  • Transfer RNA 100%
  • Reverse Transcription 80%
  • Infections 43%
  • Murine Leukemia Viruses 34%
  • Binding Sites 20%
  6 Citationer (Scopus)
• 2001

  Transfer of primer binding site-mutated simian immunodeficiency virus vectors by genetically engineered artificial and hybrid tRNA-like primers.

  Hansen, A. C., Grunwald, T., Lund, A. H., Schmitz, A., Duch, M., Uberla, K. & Pedersen, F. S., 2001, I: Journal of Virology. 75, 10, s. 4922-8 6 s.

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  • Simian immunodeficiency virus 100%
  • Simian Immunodeficiency Virus 87%
  • Transfer RNA 74%
  • binding sites 58%
  • RNA, Transfer, Pro 53%
  8 Citationer (Scopus)
• 2000

  Alleviation of murine leukemia virus repression in embryonic carcinoma cells by genetically engineered primer binding sites and artificial tRNA primers

  Modin, C., Lund, A. H., Schmitz, A., Duch, M. R. & Pedersen, F. S., 20 dec. 2000, I: Virology. 278, 2, s. 368-79 12 s.

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  • Murine Leukemia Viruses 100%
  • Transfer RNA 83%
  • Binding Sites 58%
  • Carcinoma 50%
  • Proline 15%
  14 Citationer (Scopus)

• Identification of a novel human tRNA(Ser(CGA)) functional in murine leukemia virus replication.

  Lund, A. H., Schmitz, A., Pedersen, F. S. & Duch, M., 2000, I: BBA General Subjects. 1492, 1, s. 264-8 4 s.

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  • tRNA(Ser) 100%
  • RNA, Transfer, Ser 89%
  • Murine Leukemia Viruses 69%
  • Virus Replication 53%
  • Transfer RNA 43%
  5 Citationer (Scopus)

• Mutations of the kissing-loop dimerization sequence influence the site specificity of murine leukemia virus recombination in vivo.

  Mikkelsen, J. G., Lund, A. H., Duch, M. & Pedersen, F. S., 2000, I: Journal of Virology. 74, 2, s. 600-10 10 s.

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  • Murine leukemia virus 100%
  • Murine Leukemia Viruses 93%
  • dimerization 87%
  • Dimerization 80%
  • Genetic Recombination 68%
  30 Citationer (Scopus)

• Selection of functional tRNA primers and primer binding site sequences from a retroviral combinatorial library: identification of new functional tRNA primers in murine leukemia virus replication.

  Lund, A. H., Duch, M. & Pedersen, F. S., 2000, I: Nucleic Acids Research. 28, 3, s. 791-9 8 s.

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  • Murine Leukemia Viruses 100%
  • Transfer RNA 83%
  • Virus Replication 76%
  • RNA, Transfer, Pro 67%
  • Binding Sites 58%
  12 Citationer (Scopus)

• Sint1, a common integration site in SL3-3-induced T-cell lymphomas, harbors a putative proto-oncogene with homology to the septin gene family.

  Sørensen, A. B., Lund, A. H., Ethelberg, S., Copeland, N. G., Jenkins, N. A. & Pedersen, F. S., 2000, I: Journal of Virology. 74, 5, s. 2161-8 7 s.

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  • T-cell lymphoma 100%
  • Septins 97%
  • Virus Integration 87%
  • proviruses 87%
  • proto-oncogenes 84%
  35 Citationer (Scopus)

• Sustained systemic delivery of monoclonal antibodies by genetically modified skin fibroblasts.

  Noël, D., Pelegrin, M., Brockly, F., Lund, A. H. & Piechaczyk, M., 2000, I: Journal of Investigative Dermatology. 115, 4, s. 740-5 5 s.

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  • Fibroblasts 100%
  • Monoclonal Antibodies 98%
  • Antibodies 74%
  • Skin 73%
  • Immunoglobulin Genes 34%
  15 Citationer (Scopus)
• 1999

  Forced recombination of psi-modified murine leukaemia virus-based vectors with murine leukaemia-like and VL30 murine endogenous retroviruses.

  Mikkelsen, J. G., Lund, A. H., Duch, M. & Pedersen, F. S., 1999, I: Journal of General Virology. 80 ( Pt 11), s. 2957-67 10 s.

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  • Endogenous Retroviruses 100%
  • Murine Leukemia Viruses 96%
  • Genetic Recombination 70%
  • Leukemia 60%
  • RNA 50%
  6 Citationer (Scopus)

• Replication and pathogenicity of primer binding site mutants of SL3-3 murine leukemia viruses.

  Lund, A. H., Schmidt, J., Luz, A., Sørensen, A. B., Duch, M. & Pedersen, F. S., 1999, I: Journal of Virology. 73, 7, s. 6117-22 5 s.

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  • Murine leukemia virus 100%
  • Murine Leukemia Viruses 93%
  • Virulence 62%
  • binding sites 60%
  • pathogenicity 57%
  13 Citationer (Scopus)

• The kissing-loop motif is a preferred site of 5' leader recombination during replication of SL3-3 murine leukemia viruses in mice.

  Lund, A. H., Mikkelsen, J. G., Schmidt, J., Duch, M. & Pedersen, F. S., 1999, I: Journal of Virology. 73, 11, s. 9614-8 4 s.

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  • Murine leukemia virus 100%
  • Murine Leukemia Viruses 93%
  • Genetic Recombination 68%
  • mice 41%
  • binding sites 40%
  21 Citationer (Scopus)

• The nucleotide sequence of the high-leukemogenic murine retrovirus SL3-3 reveals a patch of mink cell focus forming-like sequences upstream of the ecotropic envelope gene. Brief report.

  Lund, A. H. & Pedersen, F. S., 1999, I: Archives of Virology. 144, 11, s. 2207-12 5 s.

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  • Mink 100%
  • Retroviridae 76%
  • Viruses 47%
  • Genes 28%
  • Murine Leukemia Viruses 23%
  3 Citationer (Scopus)
• 1998

  Extended minus-strand DNA as template for R-U5-mediated second-strand transfer in recombinational rescue of primer binding site-modified retroviral vectors.

  Mikkelsen, J. G., Lund, A. H., Dybkaer, K., Duch, M. & Pedersen, F. S., 1998, I: Journal of Virology. 72, 3, s. 2519-25 6 s.

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  • retroviral vectors 100%
  • binding sites 55%
  • Binding Sites 50%
  • DNA 36%
  • Murine leukemia virus 22%
  14 Citationer (Scopus)

• Recombination in the 5' leader of murine leukemia virus is accurate and influenced by sequence identity with a strong bias toward the kissing-loop dimerization region.

  Mikkelsen, J. G., Lund, A. H., Duch, M. & Pedersen, F. S., 1998, I: Journal of Virology. 72, 9, s. 6967-78 11 s.

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  • Murine leukemia virus 100%
  • Murine Leukemia Viruses 93%
  • dimerization 87%
  • Dimerization 80%
  • Genetic Recombination 68%
  34 Citationer (Scopus)
• 1997

  Complementation of a primer binding site-impaired murine leukemia virus-derived retroviral vector by a genetically engineered tRNA-like primer.

  Lund, A. H., Duch, M., Lovmand, J., Jørgensen, P. & Pedersen, F. S., 1997, I: Journal of Virology. 71, 2, s. 1191-5 4 s.

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  • retroviral vectors 100%
  • Murine leukemia virus 91%
  • Murine Leukemia Viruses 86%
  • Transfer RNA 71%
  • binding sites 55%
  33 Citationer (Scopus)
• 1996

  A preferred region for recombinational patch repair in the 5' untranslated region of primer binding site-impaired murine leukemia virus vectors.

  Mikkelsen, J. G., Lund, A. H., Kristensen, K. D., Duch, M., Sørensen, M. S., Jørgensen, P. & Pedersen, F. S., 1996, I: Journal of Virology. 70, 3, s. 1439-47 8 s.

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  • Murine leukemia virus 100%
  • Murine Leukemia Viruses 93%
  • 5' Untranslated Regions 83%
  • 5' untranslated regions 78%
  • binding sites 60%
  45 Citationer (Scopus)

• Increased cloning efficiency by temperature-cycle ligation.

  Lund, A. H., Duch, M. & Pedersen, F. S., 1996, I: Nucleic Acids Research. 24, 4, s. 800-1 1 s.

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  57 Citationer (Scopus)

• Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein.

  Jacobsen, L., Madsen, P., Moestrup, S. K., Lund, A. H., Tommerup, N., Nykjaer, A., Sottrup-Jensen, L., Gliemann, J. & Petersen, C. M., 1996, I: Journal of Biological Chemistry. 271, 49, s. 31379-83 4 s.

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  • LDL-Receptor Related Protein-Associated Protein 100%
  • Protein 21%
  • Proteins 19%
  • LDL Receptors 17%
  • Low-Density Lipoprotein 13%
  205 Citationer (Scopus)

• Transcriptional Silencing of Retroviral Vectors.

  Lund, A. H., Duch, M. & Pedersen, F. S., 1996, I: Journal of Biomedical Science. 3, 6, s. 365-378 13 s.

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  • Enhancer 100%
  • Binding Site 59%
  • Animal Models 40%
  • Murine Leukemia Viruses 36%
  • Myoblasts 32%
  33 Citationer (Scopus)
• 1993

  Mutated primer binding sites interacting with different tRNAs allow efficient murine leukemia virus replication.

  Lund, A. H., Duch, M., Lovmand, J., Jørgensen, P. & Pedersen, F. S., 1993, I: Journal of Virology. 67, 12, s. 7125-30 5 s.

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  • Murine leukemia virus 100%
  • Murine Leukemia Viruses 93%
  • virus replication 79%
  • Transfer RNA 78%
  • Virus Replication 71%
  47 Citationer (Scopus)