Anan Yaghmur

2019

A hydrodynamic flow focusing microfluidic device for the continuous production of hexosomes based on docosahexaenoic acid monoglyceride

Yaghmur, A., Ghazal, A., Ghazal, R., Dimaki, M. & Svendsen, W. E., 28 Jun 2019, In: Physical chemistry chemical physics : PCCP. 21, 24, p. 13005-13013 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Citrem-phosphatidylcholine nano-self-assemblies: solubilization of bupivacaine and its role in triggering a colloidal transition from vesicles to cubosomes and hexosomes

Prajapati, R., Larsen, S. W. & Yaghmur, A., 21 Jul 2019, In: Physical Chemistry Chemical Physics. 21, 27, p. 15142-15150

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

From Structure to Function: pH-Switchable Antimicrobial Nano-Self-Assemblies

Gontsarik, M., Yaghmur, A., Ren, Q., Maniura-Weber, K. & Salentinig, S., 23 Jan 2019, In: A C S Applied Materials and Interfaces. 11, 3, p. 2821–2829

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

Internal Lamellar and Inverse Hexagonal Liquid Crystalline Phases During the Digestion of Krill and Astaxanthin Oil-in-Water Emulsions

Yaghmur, A., Lotfi, S., Ariabod, S. A., Bor, G., Gontsarik, M. & Salentinig, S., 5 Dec 2019, In: Frontiers in Bioengineering and Biotechnology. 7, 12 p., 00384.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

4 Downloads (Pure)

Nanoencapsulation of Food Ingredients by Cubosomes and Hexosomes

Yaghmur, A., 2019, Lipid-Based Nanostructures for Food Encapsulation Purposes. Elsevier Ltd. Academic Press, Vol. 2. 483 p. (Elsevier Book Series).

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Nanomedicines for cancer therapy: current status, challenges and future prospects

Bor, G., Mat Azmi, I. D. & Yaghmur, A., Feb 2019, In: Therapeutic Delivery. 10, 2, p. 113-132 20 p.

Research output: Contribution to journal › Journal article › Research › peer-review

43 Citations (Scopus)

pH-Responsive Nano-Self-Assemblies of the Anticancer Drug 2-Hydroxyoleic Acid

Prajapati, R., Gontsarik, M., Yaghmur, A. & Salentinig, S., 18 Jun 2019, In: Langmuir. 35, 24, p. 7954-7961

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

The Interplay Between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses

Moghimi, S. M., Simberg, D., Skotland, T., Yaghmur, A. & Hunter, A. C., 1 Sept 2019, In: Journal of Pharmacology and Experimental Therapeutics. 370, 3, p. 581-592

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Transport characteristics in a novel in vitro release model for testing the performance of intra-articular injectables

Mertz, N., Ostergaard, J., Yaghmur, A. & Larsen, S. W., 20 Jul 2019, In: International Journal of Pharmaceutics. 566, p. 445-453

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

2018

Cisplatin Encapsulation Generates Morphologically Different Multicompartments in the Internal Nanostructures of Nonlamellar Liquid-Crystalline Self-Assemblies

Azmi, I. D. M., Østergaard, J., Stürup, S., Gammelgaard, B., Urtti, A., Moghimi, S. M. & Yaghmur, A., 5 Jun 2018, In: Langmuir : the ACS journal of surfaces and colloids. 34, 22, p. 6570-6581 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

pH-Triggered nanostructural transformations in antimicrobial peptide/oleic acid self-assemblies

Gontsarik, M., Mohammadtaheri, M., Yaghmur, A. & Salentinig, S., Apr 2018, In: Biomaterials Science. 6, 4, p. 803-812 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

Structural characterization of self-assemblies of new omega-3 lipids: docosahexaenoic acid and docosapentaenoic acid monoglycerides

Shao, X., Bor, G., Al-Hosayni, S., Salentinig, S. & Yaghmur, A., 7 Oct 2018, In: Physical chemistry chemical physics : PCCP. 20, 37, p. 23928-23941 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Temperature triggering of kinetically trapped self-assemblies in citrem-phospholipid nanoparticles

Prajapati, R., Salentinig, S. & Yaghmur, A., Nov 2018, In: Chemistry and Physics of Lipids. 216, p. 30-38 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

2017

Adjuvants based on synthetic mycobacterial cord factor analogues: Biophysical properties of neat glycolipids and nano-self-assemblies with DDA

Kallerup, R. S., Franzyk, H., Schiøth, M. L., Justesen, S., Martin-Bertelsen, B., Rose, F., Madsen, C. M., Christensen, D., Korsholm, K. S., Yaghmur, A. & Foged, C., 3 Jul 2017, In: Molecular Pharmaceutics. 14, 7, p. 2294-2306 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Direct monitoring of lipid transfer on exposure of citrem nanoparticles to an ethanol solution containing soybean phospholipids by combining synchrotron SAXS with microfluidics

Khaliqi, K., Ghazal, A., Mat Azmi, I. D., Amenitsch, H., Mortensen, K., Salentinig, S. & Yaghmur, A., 7 Sept 2017, In: The Analyst. 142, 17, p. 3118-3126

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

In Situ Monitoring of Nanostructure Formation during the Digestion of Mayonnaise

Salentinig, S., Amenitsch, H. & Yaghmur, A., 30 Apr 2017, In: ACS Omega. 2, 4, p. 1441-1446 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

101 Downloads (Pure)

Microfluidic Platform for the Continuous Production and Characterization of Multilamellar Vesicles: A Synchrotron Small-Angle X-ray Scattering (SAXS) Study

Ghazal, A., Gontsarik, M., Kutter, J. P., Lafleur, J. P., Ahmadvand, D., Labrador, A., Salentinig, S. & Yaghmur, A., 5 Jan 2017, In: The Journal of Physical Chemistry Letters. 17, p. 73-79 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Structural Investigation of Bulk and Dispersed Inverse Lyotropic Hexagonal Liquid Crystalline Phases of Eicosapentaenoic Acid Monoglyceride

Yaghmur, A., Al-Hosayni, S., Amenitsch, H. & Salentinig, S., 12 Dec 2017, In: Langmuir. 33, 49, p. 14045-14057

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

2016

An integrated assessment of morphology, size, and complement activation of the PEGylated liposomal doxorubicin products Doxil®, Caelyx®, DOXOrubicin, and SinaDoxosome

Wibroe, P. P., Ahmadvand, D., Oghabian, M. A., Yaghmur, A. & Moghimi, S. M., 10 Jan 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 221, p. 1-8 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

112 Citations (Scopus)

Antimicrobial Peptide-Driven Colloidal Transformations in Liquid-Crystalline Nanocarriers

Gontsarik, M., Buhmann, M. T., Yaghmur, A., Ren, Q., Maniura-Weber, K. & Salentinig, S., 1 Sept 2016, In: Journal of Physical Chemistry Letters. 7, 17, p. 3482-3486 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

48 Citations (Scopus)

A structurally diverse library of safe-by-design citrem-phospholipid lamellar and non-lamellar liquid crystalline nano-assemblies

Mat Azmi, I. D. B., Wibroe, P. P., Wu, L-P., Kazem, A. I., Amenitsch, H., Moghimi, S. M. & Yaghmur, A., 10 Oct 2016, In: Journal of Controlled Release. 239, p. 1-9 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

45 Citations (Scopus)

Conserved molecular superlattices in a series of homologous synthetic mycobacterial cell-wall lipids forming interdigitated bilayers

Martin-Bertelsen, B., Yaghmur, A., Franzyk, H., Justesen, S., Kirkensgaard, J. J. K. & Foged, C., 6 Dec 2016, In: Langmuir. 32, 48, p. 12693–12701 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System.

Jing, X., Foged, C., Martin-Bertelsen, B., Yaghmur, A., Knapp, K. M., Malmsten, M., Franzyk, H. & Nielsen, H. M., 6 Jun 2016, In: Molecular Pharmaceutics. 13, 6, p. 1739-1749 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Direct monitoring of calcium-triggered phase transitions in cubosomes using small-angle X-ray scattering combined with microfluidics

Ghazal, A., Gontsarik, M., Kutter, J. P., Lafleur, J. P., Labrador, A., Mortensen, K. & Yaghmur, A., 1 Dec 2016, In: Journal of Applied Crystallography. 49, 6, p. 2005-2014 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

102 Downloads (Pure)

Effects of High Pressure on Internally Self-Assembled Lipid Nanoparticles: A Synchrotron Small-Angle X-ray Scattering (SAXS) Study

Kulkarni, C. V., Yaghmur, A., Steinhart, M., Kriechbaum, M. & Rappolt, M., 15 Nov 2016, In: Langmuir : the ACS journal of surfaces and colloids. 32, 45, p. 11907–11917 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Liquid crystalline nanoparticles as drug nanocarriers

Yaghmur, A. & Rappolt, M., 19 Apr 2016, Colloids in Drug Delivery. CRC Press, p. 337-354 18 p.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

7 Citations (Scopus)

Microemulsions as Potential Carriers of Nisin: Effect of Composition on Structure and Efficacy

Chatzidaki, M. D., Papadimitriou, K., Alexandraki, V., Tsirvouli, E., Chakim, Z., Ghazal, A., Mortensen, K., Yaghmur, A., Salentinig, S., Papadimitriou, V., Tsakalidou, E. & Xenakis, A., 6 Sept 2016, In: Langmuir. 32, 35, p. 8988-8998

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Nano-self-assemblies based on synthetic analogues of mycobacterial monomycoloyl glycerol and DDA: Supramolecular structure and adjuvant efficacy

Martin-Bertelsen, B., Korsholm, K. S., Christensen, D., Franzyk, H., Yaghmur, A. & Foged, C., 1 Aug 2016, In: Molecular Pharmaceutics. 13, 8, p. 2771-2781 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Role of Electrostatic Interactions on the Transport of Druglike Molecules in Hydrogel-Based Articular Cartilage Mimics: Implications for Drug Delivery

Ye, F., Baldursdottir, S., Hvidt, S., Jensen, H., Larsen, S. W., Yaghmur, A., Larsen, C. & Østergaard, J., 7 Mar 2016, In: Molecular Pharmaceutics. 13, 3, p. 819-28 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

2015

Biophysical and nanostructural properties of trehalose 6-mono and 6,6’-diesters

Madsen, C. M., Martin-Bertelsen, B., Kallerup, R. S., Rose, F., Christensen, D., Yaghmur, A., Franzyk, H. & Foged, C., 2015. 1 p.

Research output: Contribution to conference › Poster › Research

Citrem Modulates Internal Nanostructure of Glyceryl Monooleate Dispersions and Bypasses Complement Activation: Towards Development of Safe Tunable Intravenous Lipid Nanocarriers

Wibroe, P. P., Mat Azmi, I. D. B., Nilsson, C., Yaghmur, A. & Moghimi, S. M., 1 Nov 2015, In: Nanomedicine: Nanotechnology, Biology and Medicine. 11, 8, p. 1909-14 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

44 Citations (Scopus)

Cubosomes and hexosomes as versatile platforms for drug delivery

Mat Azmi, I. D. B., Moghimi, S. M. & Yaghmur, A., Dec 2015, In: Therapeutic Delivery. 6, 12, p. 1347-64 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

81 Citations (Scopus)

Formulation and characterization of food-grade microemulsions as carriers of natural phenolic antioxidants

Chatzidaki, M. D., Mitsou, E., Yaghmur, A., Zenakis, A. & Papadimitriou, V., 20 Oct 2015, In: Colloids and Surfaces A: Physicochemical and Engineering Aspects. 483, p. 130-136 7 p., 483.

Research output: Contribution to journal › Journal article › Research › peer-review

45 Citations (Scopus)

Mechanistic profiling of the siRNA delivery dynamics of lipid-polymer hybrid nanoparticles

Colombo, S., Cun, D., Remaut, K., Bunker, M., Zhang, J., Martin-Bertelsen, B., Yaghmur, A., Braeckmans, K., Nielsen, H. M. & Foged, C., 10 Mar 2015, In: Journal of Controlled Release. 201, p. 22-31 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

50 Citations (Scopus)

Modulatory Effect of Human Plasma on the Internal Nanostructure and Size Characteristics of Liquid-Crystalline Nanocarriers

Mat Azmi, I. D. B., Wu, L., Wibroe, P. P., Nilsson, C., Østergaard, J., Stürup, S., Gammelgaard, B., Urtti, A., Moghimi, S. M. & Yaghmur, A., 12 May 2015, In: Langmuir. 31, 18, p. 5042–49 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

Recent advances in cryo-TEM imaging of soft lipid nanoparticles

Helvig, S. Y., Mat Azmi, I. D. B., Moghimi, S. M. & Yaghmur, A., 2015, In: AIMS Biophysics. 2, 2, p. 116-130 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

2014

Drug formulations based on self-assembled liquid crystalline nanostructures

Yaghmur, A., Østergaard, J., Larsen, S. W., Jensen, H., Larsen, C. S. & Rappolt, M., 1 Jan 2014, Liposomes, lipid bilayers and model membranes: From basic research to application. Pabst, G., Kucerka, N., Nieh, M-P. & Katsaras, J. (eds.). Boca Raton: CRC Press, p. 341-360

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Influence of oleic acid on self-assembled liquid crystalline nanostructures

Yaghmur, A. & Azmi, I. D. M., 1 Apr 2014, Oleic Acid: Productioin, uses and potential health effects. Whelan, L. (ed.). New York: Nova Science Publishers, p. 9-34

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

PEGylation of Phytantriol-Based Lyotropic Liquid Crystalline Particles-The Effect of Lipid Composition, PEG Chain Length, and Temperature on the Internal Nanostructure

Nilsson, C., Ostergaard, J., Larsen, S. W., Larsen, C., Urtti, A. & Yaghmur, A., 10 Jun 2014, In: Langmuir : the ACS journal of surfaces and colloids. 30, 22, p. 6398-6407 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

41 Citations (Scopus)

The supramolecular structure is decisive for the immunoactivity of a mycobacterial lipid in vitro.

Martin-Bertelsen, B., Korsholm, K. S., Christensen, D., Franzyk, H., Yaghmur, A. & Foged, C., 2014. 1 p.

Research output: Contribution to conference › Poster › Research

2013

How the chain configuration governs the packing of inverted micelles in the cubic Fd3m-phase

Rappolt, M., Cacho-Nerin, F., Morello, C. & Yaghmur, A., 24 Jul 2013, In: Soft Matter. 9, 27, p. 6291-6300

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

Influence of vitamin E acetate and other lipids on the phase behavior of mesophases based on usaturated monoglycerides

Sagalowicz, L., Guillot, S., Acquistapace, S., Schmitt, B., Maurer, M., Yaghmur, A., Campo, L. D., Rouvet, M., Leser, M. & Glatter, O., 2 Jul 2013, In: Langmuir. 29, 26, p. 8222-8232

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

In situ forming drug delivery systems based on lyotropic liquid crystalline phases : structural characterization and release properties

Yaghmur, A., Rappolt, M. & Larsen, S. W., 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 325-332

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

Interaction of Amino Acid and Dipeptide beta-Naphthylamide Derivatives with Hyaluronic Acid and Human Serum Albumin Studied by Capillary Electrophoresis Frontal Analysis

Ye, F., Xie, Y., Jensen, H., Larsen, S. W., Yaghmur, A., Larsen, C. & Ostergaard, J., Jan 2013, In: Chromatographia. 76, 1-2, p. 49-57

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Nanostructured aqueous dispersions of citrem interacting with lipids and PEGylated lipids

Hedegaard, S. F., Nilsson, C., Laurinmäki, P., Butcher, S., Urtti, A. & Yaghmur, A., 14 Dec 2013, In: RSC Advances. 3, 46, p. 24576-24585 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

SPECT/CT imaging of radiolabeled cubosomes and hexosomes for potential theranostic applications

Nilsson, C., Barrios-Lopez, B., Kallinen, A., Laurinmäki, P., Butcher, S. J., Raki, M., Weisell, J., Bergström, K., Larsen, S. W., Ostergaard, J., Larsen, C., Urtti, A., Airaksinen, A. J. & Yaghmur, A., Nov 2013, In: Biomaterials. 34, 33, p. 8491-8503

Research output: Contribution to journal › Journal article › Research › peer-review

61 Citations (Scopus)

The micellar cubic Fd3m phase: recent advances in the structural characterization and potential

Yaghmur, A. & Rappolt, M., 2013, Advances in Planar Lipid Bilayers and Liposomes. Elsevier, Vol. 18. p. 111-145

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

The supramolecular structure is decisive for the immunostimulatory properties of synthetic analogues of a mycobacterial lipid in vitro

Martin-Bertelsen, B., Korsholm, K. S., Rose, F., Nordly, P. J., Franzyk, H., Andersen, P., Agger, E. M., Christensen, D., Yaghmur, A. & Foged, C., 21 Nov 2013, In: R S C Advances. 3, 43, p. 20673-20683

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Use of in vitro release models in the design of sustained and localized drug delivery systems for subcutaneous and intra-articular administration

Larsen, S. W., Østergaard, J., Yaghmur, A., Jensen, H. & Larsen, C., 2013, In: Journal of Drug Delivery Science and Technology. 23, p. 333-345

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

2012

Characterization of bupivacaine-loaded formulations based on liquid crystalline phases and microemulsions: the effect of lipid composition

Yaghmur, A., Rappolt, M., Østergaard, J., Larsen, C. S. & Larsen, S. W., 7 Feb 2012, In: Langmuir. 28, 5, p. 2881-2889

Research output: Contribution to journal › Journal article › Research › peer-review

58 Citations (Scopus)

Anan Yaghmur

Research output

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