Genome Research and Molecular Bio Medicine

Research output

Research output per year 1995 2013 2014 2015 2016 2017 2018 2019 2020

• 421 Journal article
• 22 Ph.D. thesis
• 20 Letter
• 11 Review
• 19 More
  • 8 Conference abstract in journal
  • 3 Book chapter
  • 3 Comment/debate
  • 2 Report
  • 1 Article in proceedings
  • 1 Conference abstract for conference
  • 1 Editorial

Research output per year

Research output per year

Search results

• 2018

  Noninvasive prenatal test for FGFR3-related skeletal dysplasia based on next-generation sequencing and plasma cell-free DNA: Test performance analysis and feasibility exploration

  Ren, Y., Zhao, J., Li, R., Xie, Y., Jiang, S., Zhou, H., Liu, H., You, Y., Chen, F., Wang, W., Gao, Y., Meng, Y. & Lu, Y., Oct 2018, In: Prenatal Diagnosis. 38, 11, p. 821-828

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Receptor, Fibroblast Growth Factor, Type 3 100%
  • Cell-Free Nucleic Acids 81%
  • Plasma Cells 65%
  • High-Throughput Nucleotide Sequencing 62%
  • Type I Thanatophoric Dysplasia 50%
  6 Citations (Scopus)

• Perturbations of NAD⁺ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle

  Andersen, M. A., Dall, M., Jensen, B. A. H., Prats, C., Madsen, S., Basse, A. L., Graae, A-S., Risis, S., Goldenbaum, J., Quistorff, B., Larsen, S., Vienberg, S. G. & Treebak, J. T., Apr 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 4, p. E377-E395 19 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Myoblasts 100%
  • NAD 89%
  • Skeletal Muscle 69%
  • Homeostasis 64%
  • Nicotinamide Phosphoribosyltransferase 61%
  19 Citations (Scopus)

• Recovery of gut microbiota of healthy adults following antibiotic exposure

  Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., Pyl, P. T., Coelho, L. P., Yang, H., Wang, J., Typas, A., Nielsen, M. F., Nielsen, H. B., Bork, P., Wang, J., Vilsbøll, T., & 4 othersHansen, T., Knop, F. K., Arumugam, M. & Pedersen, O., 1 Nov 2018, In: Nature Microbiology. 3, 11, p. 1255-1265 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gastrointestinal Microbiome 100%
  • Anti-Bacterial Agents 66%
  • Microbial Drug Resistance 40%
  • Genes 32%
  • Lactams 28%
  143 Citations (Scopus)

• Restricting glycolysis impairs brown adipocyte glucose and oxygen consumption

  Winther, S., Isidor, M. S., Basse, A. L., Skjoldborg, N., Cheung, A., Quistorff, B. & Hansen, J. B., Mar 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 3, p. E214-E223 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Brown Adipocytes 100%
  • Glycolysis 73%
  • Oxygen Consumption 69%
  • Glucose 44%
  • Isoproterenol 30%
  25 Citations (Scopus)

• Single-cell RNA-seq reveals dynamic transcriptome profiling in human early neural differentiation

  Shang, Z., Chen, D., Wang, Q., Wang, S., Deng, Q., Wu, L., Liu, C., Ding, X., Wang, S., Zhong, J., Zhang, D., Cai, X., Zhu, S., Yang, H., Liu, L., Fink, J. L., Chen, F., Liu, X., Gao, Z. & Xu, X., 18 Sept 2018, In: GigaScience. 7, 11, p. 1-19 giy117.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Transcription factors 100%
  • RNA 84%
  • RNA-Seq 81%
  • Gene Expression Profiling 72%
  • Epithelial Cells 54%
  7 Citations (Scopus)

  49 Downloads (Pure)

• Special Issue: Coevolution of Hosts and Their Microbiome

  Limborg, M. & Heeb, P., 13 Nov 2018, In: Genes. 9, 11, 3 p., 549.

  Research output: Contribution to journal › Editorial

  2 Citations (Scopus)

  53 Downloads (Pure)

• STAT3 associates with vacuolar H⁺-ATPase and regulates cytosolic and lysosomal pH

  Liu, B., Palmfeldt, J., Lin, L., Colaco, A., Clemmensen, K. K. B., Huang, J., Xu, F., Liu, X., Maeda, K., Luo, Y. & Jaattela, M., 1 Oct 2018, In: Cell Research. 28, 10, p. 996-1012

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Vacuolar Proton-Translocating ATPases 100%
  • STAT3 Transcription Factor 85%
  • Protons 18%
  • Glycolysis 9%
  • Neoplasms 8%
  26 Citations (Scopus)

  99 Downloads (Pure)

• Subchronic dietary exposure to ethoxyquin dimer induces microvesicular steatosis in male BALB/c mice

  Bernhard, A., Rasinger, J. D., Wisløff, H., Kolbjørnsen, Ø., Myrmel, L. S., Berntssen, M. H. G., Lundebye, A-K., Ørnsrud, R. & Madsen, L., Aug 2018, In: Food and Chemical Toxicology. 118, p. 608-625

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ethoxyquin 100%
  • ethoxyquin 85%
  • Dietary Exposure 74%
  • dietary exposure 71%
  • body weight 34%
  4 Citations (Scopus)

  39 Downloads (Pure)

• Targeted next-generation sequencing as a comprehensive test for Mendelian diseases: a cohort diagnostic study

  Sun, Y., Man, J., Wan, Y., Pan, G., Du, L., Li, L., Yang, Y., Qiu, L., Gao, Q., Dan, H., Mao, L., Cheng, Z., Fan, C., Yu, J., Lin, M., Kristiansen, K., Shen, Y. & Wei, X., 1 Dec 2018, In: Scientific Reports. 8, p. 1-9 11646.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • High-Throughput Nucleotide Sequencing 100%
  • Cohort Studies 71%
  • Mutation 36%
  • Technology 8%
  • Cell Line 7%
  3 Citations (Scopus)

  52 Downloads (Pure)

• The Immune Molecular Characteristic Research in the Development of Tuberculosis-associated Immune Reconstitution Inflammatory Syndrome in AIDS Patient: Research on HIV-TB-IRIS by Whole Transcriptome Sequencing of PBMCs from AIDS Patient

  Ma, J., 2018, Department of Biology, Faculty of Science, University of Copenhagen.

  Research output: Book/Report › Ph.D. thesis

• The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

  Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, D. O., Halling, J. F., Hansen, M., Al-Soud, W. A., Hansen, L., Kiilerich, P. & Pilegaard, H., Oct 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Resveratrol 100%
  • High Fat Diet 85%
  • Gastrointestinal Microbiome 84%
  • Exercise 55%
  • Dietary Supplements 29%
  13 Citations (Scopus)

  77 Downloads (Pure)

• The metagenome of the female upper reproductive tract

  Li, F., Chen, C., Wei, W., Wang, Z., Dai, J., Hao, L., Song, L., Zhang, X., Zeng, L., Du, H., Tang, H., Liu, N., Yang, H., Wang, J., Madsen, L., Brix, S., Kristiansen, K., Xu, X., Li, J., Wu, R., & 1 othersJia, H., 2018, In: GigaScience. 7, 10, p. 1-8 giy107.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Metagenome 100%
  • Microorganisms 83%
  • Microbiota 69%
  • Ascitic Fluid 60%
  • Vagina 57%
  20 Citations (Scopus)

  48 Downloads (Pure)

• Whole-genome and Transcriptome Sequencing of Prostate Cancer Identify New Genetic Alterations Driving Disease Progression

  Ren, S., Wei, G-H., Liu, D., Wang, L., Hou, Y., Zhu, S., Peng, L., Zhang, Q., Cheng, Y., Su, H., Zhou, X., Zhang, J., Li, F., Zheng, H., Zhao, Z., Yin, C., He, Z., Gao, X., Zhau, H. E., Chu, C-Y., & 42 othersWu, J. B., Collins, C., Volik, S. V., Bell, R., Huang, J., Wu, K., Xu, D., Ye, D., Yu, Y., Zhu, L., Qiao, M., Lee, H-M., Yang, Y., Zhu, Y., Shi, X., Chen, R., Wang, Y., Xu, W., Cheng, Y., Xu, C., Gao, X., Zhou, T., Yang, B., Hou, J., Liu, L., Zhang, Z., Zhu, Y., Qin, C., Shao, P., Pang, J., Chung, L. W. K., Xu, J., Wu, C-L., Zhong, W., Xu, X., Li, Y., Zhang, X., Wang, J., Yang, H., Wang, J., Huang, H. & Sun, Y., Mar 2018, In: European Urology. 73, 3, p. 322-339 18 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Whole Exome Sequencing 100%
  • Whole Genome Sequencing 97%
  • Disease Progression 67%
  • Prostatic Neoplasms 66%
  • Prostate 21%
  52 Citations (Scopus)

• Whole-genome sequencing of 175 Mongolians uncovers population-specific genetic architecture and gene flow throughout North and East Asia

  Bai, H., Guo, X., Narisu, N., Lan, T., Wu, Q., Xing, Y., Zhang, Y., Bond, S. R., Pei, Z., Zhang, Y., Zhang, D., Jirimutu, J., Zhang, D., Yang, X., Morigenbatu, M., Zhang, L., Ding, B., Guan, B., Cao, J., Lu, H., & 38 othersLiu, Y., Li, W., Dang, N., Jiang, M., Wang, S., Xu, H., Wang, D., Liu, C., Luo, X., Gao, Y., Li, X., Wu, Z., Yang, L., Meng, F., Ning, X., Hashenqimuge, H., Wu, K., Wang, B., Suyalatu, S., Liu, Y., Ye, C., Wu, H., Leppälä, K., Li, L., Fang, L., Chen, Y., Xu, W., Li, T., Liu, X., Xu, X., Gignoux, C. R., Yang, H., Brody, L. C., Wang, J., Kristiansen, K., Burenbatu, B., Zhou, H. & Yin, Y., 1 Dec 2018, In: Nature Genetics. 50, 12, p. 1696-1704

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Northern Asia 100%
  • Gene Flow 92%
  • Population Genetics 76%
  • Far East 75%
  • Whole Genome Sequencing 72%
  16 Citations (Scopus)

• Zinc finger and interferon-stimulated genes play a vital role in TB-IRIS following HAART in AIDS

  Ma, J., Zhao, F., Su, W., Li, Q., Li, J., Ji, J., Deng, Y., Zhou, Y., Wang, X., Yang, H., Saksena, N. K., Kristiansen, K., Wang, H. & Liu, Y., 2018, In: Personalized Medicine. 15, 4, p. 251-269

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Immune Reconstitution Inflammatory Syndrome 100%
  • Zinc Fingers 77%
  • Highly Active Antiretroviral Therapy 77%
  • Interferons 63%
  • Acquired Immunodeficiency Syndrome 57%
  2 Citations (Scopus)

  37 Downloads (Pure)
• 2017

  Acute infection with the intestinal parasite Trichuris muris has long-term consequences on mucosal mast cell homeostasis and epithelial integrity

  Sorobetea, D., Holm, J. B., Henningsson, H., Kristiansen, K. & Svensson-Frej, M., 1 Feb 2017, In: European Journal of Immunology. 47, 2, p. 257-268 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Trichuris 100%
  • Mast Cells 68%
  • Parasites 58%
  • Homeostasis 52%
  • Infections 33%
  9 Citations (Scopus)

• Analyses of gut microbiota and plasma bile acids enable stratification of patients for antidiabetic treatment

  Gu, Y., Wang, X., Li, J., Zhang, Y., Zhong, H., Liu, R., Zhang, D., Feng, Q., Xie, X., Hong, J., Ren, H., Liu, W., Ma, J., Su, Q., Zhang, H., Yang, J., Wang, X., Zhao, X., Gu, W., Bi, Y., & 11 othersPeng, Y., Xu, X., Xia, H., Li, F., Xu, X., Yang, H., Xu, G., Madsen, L., Kristiansen, K., Ning, G. & Wang, W., 1 Dec 2017, In: Nature Communications. 8, 12 p., 1785.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Acarbose 100%
  • Bile Acid 83%
  • stratification 82%
  • Bile Acids and Salts 74%
  • Gastrointestinal Microbiome 71%
  133 Citations (Scopus)

  231 Downloads (Pure)

• Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion

  Danish Pan Genome Consortium, Sørensen, L. M., Petersen, B., Sibbesen, J. A., Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Hansen, T., Krogh, A., Sørensen, T. I. A., Pedersen, O. B., Rasmussen, S., Kristiansen, K. & Brunak, S., Aug 2017, In: PLOS Genetics. 13, 8, p. e1006834

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Chromosomes, Human, Y 100%
  • Gene Conversion 84%
  • gene conversion 78%
  • Y Chromosome 76%
  • Y chromosome 67%
  15 Citations (Scopus)

• An esophageal squamous cell carcinoma classification system that reveals potential targets for therapy

  Xiong, T., Wang, M., Zhao, J., Liu, Q., Yang, C., Luo, W., Li, X., Yang, H., Kristiansen, K., Roy, B. & Zhou, Y., 25 Jul 2017, In: OncoTarget. 8, 30, p. 49851-49860 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Esophageal Squamous Cell Carcinoma 100%
  • Neoplasms 27%
  • Biodiversity 19%
  • Chromosomal Instability 17%
  • Neoplasm Metastasis 17%
  13 Citations (Scopus)

  75 Downloads (Pure)

• A safflower oil based high-fat/high-sucrose diet modulates the gut microbiota and liver phospholipid profiles associated with early glucose intolerance in the absence of tissue inflammation

  Danneskiold-Samsøe, N. B., Andersen, D., Radulescu, I. D., Hansen, A. N., Brejnrod, A. D., Kragh, M., Madsen, T., Nielsen, C., Josefsen, K. E., Fretté, X., Fjære, E., Madsen, L., Hellgren, L. I., Brix, S. & Kristiansen, K., May 2017, In: Molecular Nutrition & Food Research. 61, 5, 11 p., 1600528.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Safflower Oil 100%
  • safflower oil 82%
  • Glucose Intolerance 67%
  • intestinal microorganisms 63%
  • High Fat Diet 63%
  11 Citations (Scopus)

• Assembly and analysis of 100 full MHC haplotypes from the Danish population

  Jensen, J. M., Villesen, P., Friborg, R. M., Mailund, T., Besenbacher, S., Sørensen, L. M., Petersen, B., Sibbesen, J. A., Liu, S., Skov, L., Belling, K. G., Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R., & 39 othersYe, W., Rao, J., Guo, X., Sun, J., Cao, H., Ye, C., Beusekom, J. V., Espeseth, T., Flindt, E., Halager, A. E., Hellard, S. L., Hultman, C. M., Lescai, F., Li, S., Lund, O., Løngren, P., Matey-Hernandez, M. L., Mors, O., Pedersen, C. N. S., Sicheritz-Pontén, T., Sullivan, P., Syed, A., Westergaard, D., Yadav, R., Li, N., Xu, X., Hansen, T., Bolund, L., Krogh, A., Sørensen, T. I. A., Pedersen, O. B., Gupta, R., Rasmussen, S., Børglum, A. D., Wang, J., Eiberg, H. R. L., Kristiansen, K., Brunak, S. & Schierup, M. H., Sept 2017, In: Genome Research. 27, 9, p. 1597-1607 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Haplotypes 100%
  • Genome 72%
  • Linkage Disequilibrium 60%
  • Genome-Wide Association Study 55%
  • Major Histocompatibility Complex 54%
  7 Citations (Scopus)

  150 Downloads (Pure)

• Association analysis of the MHC in Lupus nephritis

  Xu, R., Li, Q., Liu, R., Shen, J., Li, M., Zhao, M., Wang, M., Liao, Q., Mao, H., Li, Z., Zhou, N., Yin, P., Li, Y., Tang, X., Wu, T., Zhong, Z., Wang, Y., Ai, Z., Wang, O., Chen, N., & 23 othersYang, X., Fang, J., Fu, P., Gu, J., Ye, K., Chen, J., Dai, L., Liu, H., Liu, Z., Liao, Y., Wan, J., Ding, G., Zhao, J., Zhang, H., Fu, S., Sun, L., Zhang, X., Yang, H., Wang, J., Wang, J., Liu, J., Li, Y. & Yu, X., Nov 2017, In: Journal of the American Society of Nephrology. 28, 11, p. 3383-3394 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lupus Nephritis 100%
  • Amino Acids 38%
  • Odds Ratio 17%
  • HLA-A Antigens 16%
  • Confidence Intervals 16%
  7 Citations (Scopus)

• Brown adipocyte function: A study of signaling and fuel pathways

  Winther, S., 2017, Department of Biology, Faculty of Science, University of Copenhagen.

  Research output: Book/Report › Ph.D. thesis

• Characterization of immortalized human brown and white pre-adipocyte cell models from a single donor

  Markussen, L. K., Isidor, M. S., Breining, P., Andersen, E. S., Rasmussen, N. E., Petersen, L. I., Pedersen, S. B., Richelsen, B. & Hansen, J. B., 28 Sept 2017, In: PLoS ONE. 12, 9, 17 p., e0185624.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • White Adipocytes 100%
  • telomerase 93%
  • RNA-directed DNA polymerase 79%
  • Telomerase 76%
  • adipocytes 72%
  13 Citations (Scopus)

  78 Downloads (Pure)

• Characterization of RNA editome in primary and metastatic lung adenocarcinomas

  Peng, L., Lee, L. J., Xiong, H., Su, H., Rao, J., Xiao, D., He, J., Wu, K. & Liu, D., 14 Feb 2017, In: OncoTarget. 8, 7, p. 11517-11529 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • RNA Editing 100%
  • Adenocarcinoma of Lung 77%
  • RNA 50%
  • Genes 17%
  • Whole Exome Sequencing 17%
  4 Citations (Scopus)

  61 Downloads (Pure)

• Circulating FGF21 in humans is potently induced by short term overfeeding of carbohydrates

  Lundsgaard, A., Fritzen, A. M., Sjøberg, K. A., Myrmel, L. S., Madsen, L., Wojtaszewski, J., Richter, E. & Kiens, B., 1 Jan 2017, In: Molecular Metabolism. 6, 1, p. 22-29 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • fibroblast growth factor 21 100%
  • Carbohydrates 60%
  • Diet 41%
  • Dietary Carbohydrates 21%
  • Dietary Proteins 19%
  50 Citations (Scopus)

  244 Downloads (Pure)

• Comparative transcriptome analysis of PBMC from HIV patients pre- and post-antiretroviral therapy

  Zhao, F-J., Ma, J., Huang, L., Deng, Y., Li, L., Zhou, Y., Li, J., Li, S., Jiang, H., Yang, H., Gao, S., Wang, H. & Liu, Y., Jun 2017, In: Meta Gene. 12, p. 50-61 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gene Expression Profiling 100%
  • Blood Cells 79%
  • HIV 66%
  • Highly Active Antiretroviral Therapy 48%
  • Genes 28%
  4 Citations (Scopus)

  44 Downloads (Pure)

• Comprehensive genomic profiling of lung cancer using a validated panel to explore therapeutic targets in East Asian patients

  Liu, L., Liu, J., Shao, D., Deng, Q., Tang, H., Liu, Z., Chen, X., Guo, F., Lin, Y., Mao, M., Kristiansen, K., Ye, M. & He, J., Dec 2017, In: Cancer Science. 108, 12, p. 2487-2494 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lung Neoplasms 100%
  • Mutation 35%
  • erbB-1 Genes 27%
  • Neoplasms 27%
  • Atlases 22%
  34 Citations (Scopus)

  79 Downloads (Pure)

• Corrigendum: Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

  Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Voigt, A. Y., Vestergaard, H., Hercog, R., Costea, P. I., Kultima, J. R., Li, J., Jørgensen, T., Levenez, F., & 10 othersDoré, J., Nielsen, H. B., Brunak, S., Raes, J., Hansen, T., Wang, J., Ehrlich, S. D., Bork, P., Pedersen, O. & MetaHIT consortium, 3 May 2017, In: Nature. 545, 116, 1 p., 22318.

  Research output: Contribution to journal › Comment/debate › Research

  21 Citations (Scopus)

• Deep whole-genome sequencing of 90 Han Chinese genomes

  Lan, T., Lin, H., Zhu, W., Laurent, T. C. A. M., Yang, M., Liu, X., Wang, J., Wang, J., Yang, H., Xu, X. & Guo, X., 1 Sept 2017, In: GigaScience. 6, 9, p. 1-7 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Whole Genome Sequencing 100%
  • Genomics 89%
  • Genome 58%
  • High-Throughput Nucleotide Sequencing 41%
  • Polymorphism 19%
  13 Citations (Scopus)

  65 Downloads (Pure)

• Dietary intake and adipose tissue content of long-chain n-3 PUFAs and subsequent 5-y change in body weight and waist circumference

  Jakobsen, M. U., Madsen, L., Skjøth, F., Berentzen, T. L., Halkjaer, J., Tjønneland, A., Schmidt, E. B., Sørensen, T. I. A., Kristiansen, K. & Overvad, K., 1 May 2017, In: The American Journal of Clinical Nutrition. 105, 5, p. 1148-1157 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Body Weight Changes 100%
  • Omega-3 Fatty Acids 90%
  • Waist Circumference 82%
  • Adipose Tissue 68%
  • docosapentaenoic acid 37%
  7 Citations (Scopus)

• DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation

  Castillo-Fernandez, J. E., Loke, Y. J., Bass-Stringer, S., Gao, F., Xia, Y., Wu, H., Lu, H., Liu, Y., Wang, J., Spector, T. D., Saffery, R., Craig, J. M. & Bell, J. T., 24 Mar 2017, In: Genome Medicine. 9, 15 p., 28.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Fertilization in Vitro 100%
  • Twins 98%
  • DNA Methylation 91%
  • Infertility 86%
  • Newborn Infant 71%
  16 Citations (Scopus)

  66 Downloads (Pure)

• Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease

  HPS3/TIMI55–REVEAL Collaborative Group, 28 Sept 2017, In: The New England Journal of Medicine. 377, 13, p. 1217-1227 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • anacetrapib 100%
  • Vascular Diseases 53%
  • Placebos 23%
  • Cholesterol Ester Transfer Proteins 19%
  • LDL Cholesterol 18%
  448 Citations (Scopus)

• Effects of Gliadin consumption on the Intestinal Microbiota and Metabolic Homeostasis in Mice Fed a High-fat Diet

  Zhang, L., Andersen, D., Roager, H. M., Bahl, M. I., Hansen, C. H. F., Danneskiold-Samsøe, N. B., Kristiansen, K., Radulescu, I. D., Sina, C., Frandsen, H. L., Hansen, A. K., Brix, S., Hellgren, L. I. & Licht, T. R., 16 Mar 2017, In: Scientific Reports. 7, 13 p., 44613.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gliadin 100%
  • Glutens 74%
  • High Fat Diet 71%
  • Gastrointestinal Microbiome 70%
  • Homeostasis 52%
  11 Citations (Scopus)

  83 Downloads (Pure)

• Enterotypes in the landscape of gut microbial community composition

  Costea, P. I., Hildebrand, F., Manimozhiyan, A., Bäckhed, F., Blaser, M. J., Bushman, F. D., De Vos, W. M., Ehrlich, S. D., Fraser, C. M., Hattori, M., Huttenhower, C., Jeffery, I. B., Knights, D., Lewis, J. D., Ley, R. E., Ochman, H., O'Toole, P. W., Quince, C., Relman, D. A., Shanahan, F., & 9 othersSunagawa, S., Wang, J., Weinstock, G. M., Wu, G. D., Zeller, G., Zhao, L., Raes, J., Knight, R. & Bork, P., 2017, In: Nature Microbiology. 3, 1, p. 8-16 9 p.

  Research output: Contribution to journal › Review › peer-review

  • Microbiota 100%
  • Gastrointestinal Microbiome 33%
  • Data Analysis 25%
  • Health 16%
  • Population 13%
  265 Citations (Scopus)

• Eosinophilic airway inflammation in asthmatic patients is associated with an altered airway microbiome

  Sverrild, A., Kiilerich, P., Brejnrod, A. D., Pedersen, R., Porsbjerg, C., Bergqvist, A., Erjefält, J. S., Kristiansen, K. & Backer, V., Aug 2017, In: Journal of Allergy and Clinical Immunology. 140, 2, p. 407-417 e11.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Microbiota 100%
  • Inflammation 59%
  • Eosinophils 48%
  • Healthy Volunteers 33%
  • Asthma 23%
  42 Citations (Scopus)

• Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention

  Liu, R., Hong, J., Xu, X., Feng, Q., Zhang, D., Gu, Y., Shi, J., Zhao, S., Liu, W., Wang, X., Xia, H., Liu, Z., Cui, B., Liang, P., Xi, L., Jin, J., Ying, X., Wang, X., Zhao, X., Li, W., & 28 othersJia, H., Lan, Z., Li, F., Wang, R., Sun, Y., Yang, M., Shen, Y., Jie, Z., Li, J., Chen, X., Zhong, H., Xie, H., Zhang, Y., Gu, W., Deng, X., Shen, B., Xu, X., Yang, H., Xu, G., Bi, Y., Lai, S., Wang, J., Qi, L., Madsen, L., Wang, J., Ning, G., Kristiansen, K. & Wang, W., Jul 2017, In: Nature Medicine. 23, 7, p. 859-868 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Metabolome 100%
  • Bacteroides thetaiotaomicron 88%
  • Gastrointestinal Microbiome 87%
  • Weight Loss 72%
  • Glutamic Acid 62%
  397 Citations (Scopus)

• High-fat feeding rather than obesity drives taxonomical and functional changes in the gut microbiota in mice

  Xiao, L., Sonne, S. B., Feng, Q., Chen, N., Xia, Z., Li, X., Fang, Z., Zhang, D., Fjære, E., Midtbø, L. K., Derrien, M., Hugenholtz, F., Tang, L., Li, J., Zhang, J., Liu, C., Hao, Q., Vogel, U. B., Mortensen, A., Kleerebezem, M., & 8 othersLicht, T. R., Yang, H., Wang, J., Li, Y., Arumugam, M., Wang, J., Madsen, L. & Kristiansen, K., 8 Apr 2017, In: Microbiome. 5, 12 p., 43.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gastrointestinal Microbiome 100%
  • Fats 76%
  • Obesity 70%
  • High Fat Diet 40%
  • Butyrates 38%
  57 Citations (Scopus)

  91 Downloads (Pure)

• Ibuprofen results in alterations of human fetal testis development

  Ben Maamar, M., Lesné, L., Hennig, K., Desdoits-Lethimonier, C., Kilcoyne, K. R., Coiffec, I., Rolland, A. D., Chevrier, C., Kristensen, D. M., Lavoue, V., Antignac, J-P., le Bizec, B., Dejucq-Rainsford, N., Mitchell, R. T., Mazaud-Guittot, S. & Jégou, B., 10 Mar 2017, In: Scientific Reports. 7, 15 p., 44184.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ibuprofen 100%
  • Fetal Development 87%
  • Testis 75%
  • Germ Cells 21%
  • Testosterone 18%
  36 Citations (Scopus)

  137 Downloads (Pure)

• Identification of a disease-causing mutation in a Chinese patient with retinitis pigmentosa by targeted next-generation sequencing

  Xiao, J., Guo, X., Wang, Y., Shao, M., Wei, X., Du, L., Li, L., Sun, Y. & Yang, Y., 8 Nov 2017, In: European Journal of Ophthalmology. 27, 6, p. 791-796 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Retinitis Pigmentosa 100%
  • High-Throughput Nucleotide Sequencing 78%
  • Mutation 45%
  • Computational Biology 22%
  • Molecular Pathology 13%
  2 Citations (Scopus)

• Increased microvascular permeability in mice lacking Epac1 (Rapgef3)

  Kopperud, R. K., Rygh, C. B., Karlsen, T. V., Krakstad, C., Kleppe, R., Hoivik, E. A., Bakke, M., Tenstad, O., Selheim, F., Lidén, Å., Madsen, L., Pavlin, T., Taxt, T., Kristiansen, K., Curry, F. -R. E., Reed, R. K. & Døskeland, S. O., 1 Feb 2017, In: Acta Physiologica. 219, 2, p. 441-452 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Capillary Permeability 100%
  • Permeability 78%
  • gadomer 17 74%
  • Atrial Natriuretic Factor 60%
  • Albumins 31%
  19 Citations (Scopus)

  76 Downloads (Pure)

• Induction of lipogenesis in white fat during cold exposure in mice: link to lean phenotype

  Flachs, P., Adamcova, K., Zouhar, P., Marques, C., Janovska, P., Viegas, I., Jones, J. G., Bardova, K., Svobodova, M., Hansikova, J., Kuda, O., Rossmeisl, M., Aune, U. L., Borkowska, A. G., Kristiansen, K., Madsen, L. & Kopecky, J., 1 Mar 2017, In: International Journal of Obesity. 41, 3, p. 372-380 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lipogenesis 100%
  • White Adipose Tissue 98%
  • Cold Temperature 72%
  • Fatty Acids 69%
  • Triglycerides 58%
  26 Citations (Scopus)

• Integrative analysis of genomic sequencing data reveals higher prevalence of LRP1B mutations in lung adenocarcinoma patients with COPD

  Xiao, D., Li, F., Pan, H., Liang, H., Wu, K. & He, J., 1 Dec 2017, In: Scientific Reports. 7, 8 p., 2121.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Adenocarcinoma of Lung 100%
  • Lung Diseases 83%
  • Mutation 52%
  • Lung Neoplasms 39%
  • Whole Exome Sequencing 8%
  11 Citations (Scopus)

  54 Downloads (Pure)

• Isolation and phylogenetic study of Rift Valley fever virus from the first imported case to China

  Shi, Y., Zheng, K., Li, X., Li, L., Li, S., Ma, J., Dai, J., Ji, J., Yuan, S., Lu, H., Li, J., Sun, F., Xu, X. & Huang, J., Jun 2017, In: Virologica Sinica. 32, 3, p. 253-256 4 p.

  Research output: Contribution to journal › Letter › peer-review

  5 Citations (Scopus)

• Isolation and whole genome sequencing of fetal cells from maternal blood towards the ultimate non-invasive prenatal testing

  Chen, F., Liu, P., Gu, Y., Zhu, Z., Nanisetti, A., Lan, Z., Huang, Z., Liu, J. S., Kang, X., Deng, Y., Luo, L., Jiang, D., Qiu, Y., Pan, J., Xia, J., Xiong, K., Liu, C., Xie, L., Shi, Q., Li, J., & 7 othersZhang, X., Wang, W., Drmanac, S., Bolund, L., Jiang, H., Drmanac, R. & Xu, X., Dec 2017, In: Prenatal Diagnosis. 37, 13, p. 1311-1321 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Whole Genome Sequencing 100%
  • Blood Cells 70%
  • Mothers 54%
  • Microsatellite Repeats 22%
  • Genetic Testing 11%
  21 Citations (Scopus)

• Links between dietary protein sources, the gut microbiota, and obesity

  Madsen, L., Myrmel, L. S., Fjære, E., Liaset, B. & Kristiansen, K., 19 Dec 2017, In: Frontiers in Physiology. 8, 12 p., 1047.

  Research output: Contribution to journal › Review › peer-review

  • Dietary Proteins 100%
  • Gastrointestinal Microbiome 78%
  • Obesity 55%
  • Proteins 16%
  • Seafood 15%
  39 Citations (Scopus)

  80 Downloads (Pure)

• Lipidomic profiling reveals distinct differences in plasma lipid composition in healthy, prediabetic, and type 2 diabetic individuals

  Zhong, H., Fang, C., Fan, Y., Lu, Y., Wen, B., Ren, H., Hou, G., Yang, F., Xie, H., Jie, Z., Peng, Y., Ye, Z., Wu, J., Zi, J., Zhao, G., Chen, J., Bao, X., Hu, Y., Gao, Y., Zhang, J., & 7 othersYang, H., Wang, J., Madsen, L., Kristiansen, K., Ni, C., Li, J. & Liu, S., 1 Jul 2017, In: GigaScience. 6, 7, p. 1-12 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lipidomics 100%
  • Lipids 97%
  • Medical problems 80%
  • Plasmas 67%
  • Glucose 59%
  20 Citations (Scopus)

  130 Downloads (Pure)

• Mammary alveolar epithelial cells convert to brown adipocytes in post-lactating mice

  Giordano, A., Perugini, J., Kristensen, D. M., Sartini, L., Frontini, A., Kajimura, S., Kristiansen, K. & Cinti, S., Nov 2017, In: Journal of Cellular Physiology. 232, 11, p. 2923-2928 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Brown Adipocytes 100%
  • Alveolar Epithelial Cells 78%
  • Human Mammary Glands 77%
  • Brown 72%
  • Breast 53%
  14 Citations (Scopus)

• Maternal use of mild analgesics during pregnancy associated with reduced anogenital distance in sons: a cohort study of 1027 mother-child pairs

  Lind, D. V., Main, K. M., Kyhl, H. B., Kristensen, D. M., Toppari, J., Andersen, H. R., Skovsager Andersen, M., Skakkebæk, N. E. & Jensen, T. K., 1 Jan 2017, In: Human Reproduction. 32, 1, p. 223-231 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Nuclear Family 100%
  • Analgesics 80%
  • Cohort Studies 63%
  • Acetaminophen 62%
  • Mothers 59%
  33 Citations (Scopus)

• MCT1 and MCT4 expression and lactate flux activity increase during white and brown adipogenesis and impact adipocyte metabolism

  Petersen, C., Nielsen, M. D., Andersen, E. S., Basse, A. L., Isidor, M. S., Markussen, L. K., Viuff, B. M., Lambert, I. H., Hansen, J. B. & Pedersen, S. H. F., 12 Oct 2017, In: Scientific Reports. 7, 1, 13 p., 13101.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Adipogenesis 100%
  • Adipocytes 79%
  • Lactic Acid 74%
  • Thermogenesis 29%
  • Acids 26%
  28 Citations (Scopus)

  94 Downloads (Pure)