Susheel Singh

2019

Antibody responses to antigenic targets of recent exposure are associated with low-density parasitemia in controlled human Plasmodium falciparum infections

van den Hoogen, L. L., Walk, J., Oulton, T., Reuling, I. J., Reiling, L., Beeson, J. G., Coppel, R. L., Singh, S. K., Draper, S. J., Bousema, T., Drakeley, C., Sauerwein, R. & Tetteh, K. K. A., 2019, In: Frontiers in Microbiology. 9, 11 p., 3300.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

46 Downloads (Pure)

Breadth of functional antibodies is associated with Plasmodium falciparum merozoite phagocytosis and protection against febrile malaria

Kana, I. H., Singh, S. K., Garcia-Senosiain, A., Dodoo, D., Singh, S., Adu, B. & Theisen, M., 19 Jun 2019, In: The Journal of Infectious Diseases. 220, 2, p. 275-284 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Pfs230 and Pfs48/45 fusion proteins elicit strong transmission-blocking antibody responses against Plasmodium falciparum

Singh, S. K., Thrane, S., Chourasia, B. K., Teelen, K., Graumans, W., Stoter, R., van Gemert, G.-J., van de Vegte-Bolmer, M. G., Nielsen, M. A., Salanti, A., Sander, A. F., Sauerwein, R. W., Jore, M. M. & Theisen, M., 2019, In: Frontiers in Immunology. 10, p. 1256

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

2018

Cytophilic Antibodies Against Key Plasmodium falciparum Blood Stage Antigens Contribute to Protection Against Clinical Malaria in a High Transmission Region of Eastern India

Kana, I. H., Garcia Senosiain, A., Singh, S., Tiendrebeogo, R. W., Chourasia, B., Malhotra, P., Sharma, S. K., Das, M. K., Singh, S., Adu, B. & Theisen, M., 14 Aug 2018, In: The Journal of Infectious Diseases. 218, 6, p. 956-965

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern Ghana

Amoah, L. E., Acquah, F. K., Ayanful-Torgby, R., Oppong, A., Abankwa, J., Obboh, E. K., Singh, S. K. & Theisen, M., 5 Jan 2018, In: Parasites & Vectors. 11, 1, 9 p., 13.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

75 Downloads (Pure)

Lactococcus lactis provides an efficient platform for production of disulfide-rich recombinant proteins from Plasmodium falciparum

Singh, S. K., Tiendrebeogo, R. W., Chourasia, B. K., Kana, I. H., Singh, S. & Theisen, M., 5 Apr 2018, In: Microbial Cell Factories. 17, 13 p., 55.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

36 Downloads (Pure)

Plasmodium falciparum MSP3 exists in a complex on the merozoite surface and generates antibody response during natural infection

Deshmukh, A., Chourasia, B. K., Mehrotra, S., Kana, I. H., Paul, G., Panda, A., Kaur, I., Singh, S. K., Rathore, S., Das, A., Gupta, P., Kalamuddin, M., Gakhar, S. K., Mohmmed, A., Theisen, M. & Malhotra, P., 1 Aug 2018, In: Infection and Immunity. 86, 8, e00067-18.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity

Stone, W. J. R., Campo, J. J., Ouédraogo, A. L., Meerstein-Kessel, L., Morlais, I., Da, D., Cohuet, A., Nsango, S., Sutherland, C. J., van de Vegte-Bolmer, M., Siebelink-Stoter, R., van Gemert, G.-J., Graumans, W., Lanke, K., Shandling, A. D., Pablo, J. V., Teng, A. A., Jones, S., de Jong, R. M. & Fabra-García, A. & 14 others, Bradley, J., Roeffen, W., Lasonder, E., Gremo, G., Schwarzer, E., Janse, C. J., Singh, S. K., Theisen, M., Felgner, P., Marti, M., Drakeley, C., Sauerwein, R., Bousema, T. & Jore, M. M., 8 Feb 2018, In: Nature Communications. 9, 1, 14 p., 558.

Research output: Contribution to journal › Journal article › Research › peer-review

39 Citations (Scopus)

48 Downloads (Pure)

2017

A HR-MS based method for the determination of chorismate synthase activity

Khera, H. K., Singh, S. K., Mir, R., Bharadwaj, V. & Singh, S., 2017, In: Protein and Peptide Letters. 24, 3, p. 229-234 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood-stage merozoites

Paul, G., Deshmukh, A., Kaur, I., Rathore, S., Dabral, S., Panda, A., Singh, S. K., Mohmmed, A., Theisen, M. & Malhotra, P., 16 Feb 2017, In: Malaria Journal. 16, 1, 15 p., 79.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

61 Downloads (Pure)

Antibody responses to two new Lactococcus lactis-produced recombinant Pfs48/45 and Pfs230 proteins increase with age in malaria patients living in the Central Region of Ghana

Acquah, F. K., Obboh, E. K., Asare, K., Boampong, J. N., Nuvor, S. V., Singh, S. K., Theisen, M., Williamson, K. C. & Amoah, L. E., 1 Aug 2017, In: Malaria Journal. 16, 11 p., 306.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

96 Downloads (Pure)

Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine

Singh, S. K., Roeffen, W., Mistarz, U. H., Chourasia, B. K., Yang, F., Rand, K. D., Sauerwein, R. W. & Theisen, M., 31 May 2017, In: Microbial Cell Factories. 16, 1, 11 p., 97.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

87 Downloads (Pure)

Expression, Purification and Characterization of GMZ2'.10C, a Complex Disulphide-Bonded Fusion Protein Vaccine Candidate against the Asexual and Sexual Life-Stages of the Malaria-Causing Plasmodium falciparum Parasite

Mistarz, U. H., Singh, S. K., Nguyen, T. T. T. N., Roeffen, W., Yang, F., Lissau, C., Madsen, S. M., Vrang, A., Tiendrebeogo, R. W., Kana, I. H., Sauerwein, R. W., Theisen, M. & Rand, K. D., 1 Sept 2017, In: Pharmaceutical Research. 34, 9, p. 1970-1983 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display

Singh, S. K., Thrane, S., Janitzek, C. M., Nielsen, M. A., Theander, T. G., Theisen, M., Salanti, A. & Sander, A. F., 27 Jun 2017, In: Vaccine. 35, 30, p. 3726-3732 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana

Amoah, L. E., Nuvor, S. V., Obboh, E. K., Acquah, F. K., Asare, K., Singh, S. K., Boampong, J. N., Theisen, M. & Williamson, K. C., 2017, In: Parasites and Vectors. 10, 1, 9 p., 395.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

124 Downloads (Pure)

Naturally acquired antibodies target the glutamate-rich protein on intact merozoites and predict protection against febrile malaria

Kana, I. H., Adu, B., Tiendrebeogo, R. W., Singh, S. K., Dodoo, D. & Theisen, M., 15 Feb 2017, In: The Journal of Infectious Diseases. 215, 4, p. 623-630 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

2016

Controlled synthesis, bioimaging and toxicity assessments in strong red emitting Mn²⁺ doped NaYF₄:Yb³⁺/Ho³⁺ nanophosphors

Reddy, K. L., Rai, M., Prabhakar, N., Arppe, R., Rai, S. B., Singh, S. K., Rosenholm, J. M. & Krishnan, V., 2016, In: RSC Advances. 6, 59, p. 53698-53704 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

Synthetic TLR4 agonists enhance functional antibodies and CD4⁺ T-cell responses against the Plasmodium falciparum GMZ2.6C multi-stage vaccine antigen

Baldwin, S. L., Roeffen, W., Singh, S. K., Tiendrebeogo, R. W., Christiansen, M., Beebe, E., Carter, D., Fox, C. B., Howard, R. F., Reed, S. G., Sauerwein, R. & Theisen, M., 27 Apr 2016, In: Vaccine. 34, 19, p. 2207-2215 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

2015

Antibody-dependent cellular inhibition is associated with reduced risk against febrile malaria in a longitudinal cohort study involving Ghanaian children

Tiendrebeogo, R. W., Adu, B., Singh, S. K., Dziegiel, M. H., Nébié, I., Sirima, S. B., Christiansen, M., Dodoo, D. & Theisen, M., 1 Apr 2015, In: Open forum in Infectious Diseases. 2, 2, 5 p., ofv044.

Research output: Contribution to journal › Letter › peer-review

26 Citations (Scopus)

A Plasmodium falciparum 48/45 single epitope R0.6C subunit protein elicits high levels of transmission blocking antibodies

Singh, S. K., Roeffen, W., Andersen, G., Bousema, T., Christiansen, M., Sauerwein, R. & Theisen, M., 15 Apr 2015, In: Vaccine. 33, 16, p. 1981-6 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

37 Citations (Scopus)

2014

A multi-stage malaria vaccine candidate targeting both transmission and asexual parasite life-cycle stages

Theisen, M., Roeffen, W., Singh, S. K., Andersen, G., Amoah, L., van de Vegte-Bolmer, M., Arens, T., Tiendrebeogo, R. W., Jones, S., Bousema, T., Adu, B., Dziegiel, M. H., Christiansen, M. & Sauerwein, R., 7 May 2014, In: Vaccine. 32, 22, p. 2623–2630 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

66 Citations (Scopus)

High-throughput tri-colour flow cytometry technique to assess Plasmodium falciparum parasitaemia in bioassays

Tiendrebeogo, R. W., Adu, B., Singh, S. K., Dodoo, D., Dziegiel, M. H., Mordmüller, B., Nébié, I., Sirima, S. B., Christiansen, M. & Theisen, M., 2014, In: Malaria Journal. 13, 1, p. 412

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

2013

The Malaria Vaccine Candidate GMZ2 Elicits Functional Antibodies in Individuals From Malaria Endemic and Non-Endemic Areas

Jepsen, M. P. G., Jogdand, P. S., Singh, S. K., Esen, M., Christiansen, M., Issifou, S., Hounkpatin, A. B., Ateba-Ngoa, U., Kremsner, P. G., Dziegiel, M. H., Olesen-Larsen, S., Jepsen, S., Mordmüller, B. & Theisen, M., 1 Aug 2013, In: The Journal of Infectious Diseases. 208, 3, p. 479-88 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

46 Citations (Scopus)

2012

Flow cytometric readout based on Mitotracker Red CMXRos staining of live asexual blood stage malarial parasites reliably assesses antibody dependent cellular inhibition

Jogdand, P. S., Singh, S. K., Christiansen, M., Dziegiel, M. H., Singh, S. & Theisen, M., 2012, In: Malaria Journal. 11, 1, p. 235

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Susheel Singh

Research output

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