Louise Kruse Jensen

Research output

Research output per year 2009 2009 2013 2017 2018 2019 2019

• 28 Journal article
• 16 Conference abstract for conference
• 4 Poster
• 2 Ph.D. thesis
• 4 More
  • 2 Review
  • 1 Conference abstract in proceedings
  • 1 Conference abstract in journal

Research output per year

Research output per year

Search results

• 2019

  Extensive debridement is fundamental for the success of an absorbable gentamicin loaded bio-composite

  Jensen, L. K., Blirup-Plum, S. A., Aalbæk, B., Bjarnsholt, T., Kragh, K. N., Gottlieb, H., Bue, M. & Jensen, H. E., 12 Sept 2019.

  Research output: Contribution to conference › Conference abstract for conference › Communication

• Guideline for preclinical studies of bone infections

  Jensen, L. K., Henriksen, N. L., Blirup-Plum, S. A. & Jensen, H. E., 12 Sept 2019.

  Research output: Contribution to conference › Conference abstract for conference › Communication

• Guideline for Preclinical Studies of Bone Infections in Large Animals Based on a Systematic Review of 316 Non-Rodent Models

  Jensen, L. K., Henriksen, N. L., Blirup, S. A. & Jensen, H. E., 2019, In: The Journal of bone and joint surgery. American volume. 101, 21, p. 1894-1903 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Systematic Reviews 100%
  • Guidelines 87%
  • Bone and Bones 80%
  • Animals 68%
  • Infections 64%
  1 Citation (Scopus)

• Guidelines for porcine models of human bacterial infections

  Jensen, L. K., Henriksen, N. L. & Jensen, H. E., 1 Apr 2019, In: Laboratory Animals. 53, 2, p. 125-136

  Research output: Contribution to journal › Review › peer-review

  • bacterial infections 100%
  • Bacterial Infections 84%
  • Communicable Diseases 77%
  • Swine 71%
  • swine 57%
  3 Citations (Scopus)

• In vivo gentamicin susceptibility test for prevention of bacterial biofilms in bone tissue and on implants

  Jensen, L. K., Bjarnsholt, T., Kragh, K. N., Aalbæk, B., Henriksen, N. L., Blirup, S. A., Pankoke, K., Petersen, A. & Jensen, H. E., 2019, In: Antimicrobial Agents and Chemotherapy. 63, 2, e01889-18.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gentamicins 100%
  • Biofilms 94%
  • Swine 76%
  • Bone and Bones 57%
  • Bacteria 52%
  8 Citations (Scopus)

• Systematic review of 316 animal models of bone infections - a call for improved quality

  Jensen, L. K., Henriksen, N. L., Blirup, S. A. & Jensen, H. E., 21 Mar 2019.

  Research output: Contribution to conference › Conference abstract for conference › Communication

• Time-dependent Pathologic and Inflammatory Consequences of Various Blood Sampling Techniques in Mice

  Sørensen, D. B., Metzdorff, S. B., Jensen, L. K., Andersen, K. H., Teilmann, A. C., Jensen, H. E. & Frøkiær, H., May 2019, In: JAALAS - Journal of the American Association for Laboratory Animal Science. 58, 3, p. 362-372

  Research output: Contribution to journal › Journal article › Research › peer-review

  • blood sampling 100%
  • inflammation 80%
  • sinuses 62%
  • tail 54%
  • mice 50%
  3 Citations (Scopus)
• 2018

  A porcine model of S. Aureus implant-associated osteomyelitis

  Jensen, L. K., 23 Aug 2018, p. 41.

  Research output: Contribution to conference › Conference abstract for conference › Communication

• Combined Staining Techniques for Demonstration of Staphylococcus aureus Biofilm in Routine Histopathology

  Jensen, L. K., Henriksen, N. L., Bjarnsholt, T., Kragh, K. N. & Jensen, H. E., 20 Feb 2018, In: Journal of Bone and Joint Infection. 3, 1, p. 27-36

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Biofilms 100%
  • Staphylococcus aureus 87%
  • Extracellular Matrix 86%
  • Staining and Labeling 65%
  • Extracellular Polymeric Substance Matrix 58%
  81 Downloads (Pure)

• Extreme high local intra-operative gentamicin concentrations are needed to prevent biofilm formation in-vivo

  Jensen, L. K., Bjarnsholt, T., Henriksen, N. L., Kragh, K. N. & Jensen, H. E., 6 Sept 2018.

  Research output: Contribution to conference › Conference abstract for conference › Communication

• Pigs are useful for the molecular study of bone inflammation and regeneration in humans

  Lüthje, F. L., Skovgaard, K., Jensen, H. E. & Kruse Jensen, L., 1 Dec 2018, In: Laboratory Animals. 52, 6, p. 630-640

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Osteitis 100%
  • Bone Regeneration 85%
  • inflammation 69%
  • orthopedics 67%
  • bones 65%
  9 Citations (Scopus)

• Single-Dose Bone Pharmacokinetics of Vancomycin in a Porcine Implant-Associated Osteomyelitis Model

  Bue, M., Hanberg, P., Koch, J., Jensen, L. K., Lundorff, M., Aalbaek, B., Jensen, H. E., Søballe, K. & Tøttrup, M., Apr 2018, In: Journal of Orthopaedic Research. 36, 4, p. 1093-1098

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Osteomyelitis 100%
  • Vancomycin 97%
  • Swine 72%
  • Pharmacokinetics 69%
  • Bone and Bones 54%
  11 Citations (Scopus)

• The molecular and pathomorphilogical response to staphylococcus aureus induced implant associated osteomyelitis in a porcine model

  Lüthje, F. L., Skovgaard, K., Jensen, H. E. & Jensen, L. K., 23 Aug 2018, p. 347.

  Research output: Contribution to conference › Conference abstract for conference › Communication
• 2017

  Early implant-associated osteomyelitis results in a peri-implanted bacterial reservoir

  Jensen, L. K., Koch, J., Aalbæk, B., Moodley, A., Bjarnsholt, T., Kragh, K. N., Petersen, A. & Jensen, H. E., 1 Jan 2017, In: APMIS - Journal of Pathology, Microbiology and Immunology. 125, 1, p. 38-45 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Osteomyelitis 100%
  • Bone and Bones 54%
  • Staphylococcus aureus 39%
  • Swine 24%
  • Peptide Nucleic Acids 22%
  13 Citations (Scopus)

  92 Downloads (Pure)

• Histopathological diagnosis of biofilm

  Jensen, L. K., Henriksen, N. L. & Jensen, H. E., 7 Sept 2017.

  Research output: Contribution to conference › Conference abstract for conference › Communication

• Hyperpolarized ¹³C-MRSI and PET (hyperPET) in an Osteomyelitis Pig Model: A Pilot Study

  Rahbek, S., Gutte, H., Johannesen, H. H., Koch, J., Jensen, L. K., Dich-Jørgensen, K., Jensen, H. E., Hansen, A. E. & Kjær, A., Mar 2017, In: IEEE Transactions on Radiation and Plasma Medical Sciences. 1, 2, 4 p., 164-167.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • positron-emission tomography 100%
  • osteomyelitis 97%
  • magnetic resonance imaging 83%
  • abscess 79%
  • swine 40%

• Novel porcine model of implant-associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response

  Jensen, L. K., Koch, J., Dich-Jørgensen, K., Aalbaek, B., Petersen, A., Fuursted, K., Bjarnsholt, T., Kragh, K. N., Tøtterup, M., Bue, M., Hanberg, P., Søballe, K., Heegaard, P. M. H. & Jensen, H. E., Oct 2017, In: Journal of Orthopaedic Research. 35, 10, p. 2211–2221

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Osteomyelitis 100%
  • Swine 72%
  • Neutrophils 30%
  • Staphylococcus aureus 22%
  • Animal Diseases 17%
  19 Citations (Scopus)

  45 Downloads (Pure)

• Porcine models of biofilm infections

  Jensen, L. K., Johansen, A. S. B. & Jensen, H. E., 2017.

  Research output: Contribution to conference › Conference abstract for conference › Communication

• Porcine models of biofilm infections with focus on pathomorphology

  Jensen, L. K., Johansen, A. S. B. & Jensen, H. E., 10 Oct 2017, In: Frontiers in Microbiology. 8, 16 p., 1961.

  Research output: Contribution to journal › Review › peer-review

  • Biofilms 100%
  • Communicable Diseases 87%
  • Swine 80%
  • Osteomyelitis 55%
  • Infections 48%
  8 Citations (Scopus)

  59 Downloads (Pure)

• Suppurative Inflammation and Local Tissue Destruction Reduce the Penetration of Cefuroxime to Infected Bone Implant Cavities

  Jensen, L. K., Koch, J., Henriksen, N. L., Bue, M., Tøttrup, M., Hanberg, P., Søballe, K. & Jensen, H. E., 2017, In: Journal of Comparative Pathology. 157, 4, p. 308-316 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • cefuroxime 100%
  • Cefuroxime 93%
  • inflammation 64%
  • bones 59%
  • Bone and Bones 41%
  4 Citations (Scopus)

• The pig as a model for human infections

  Jensen, L. K. & Jensen, H. E., 2017.

  Research output: Contribution to conference › Conference abstract for conference › Communication
• 2016

  Effects of Implant-Associated Osteomyelitis on Cefuroxime Bone Pharmacokinetics: Assessment in a Porcine Model

  Tøttrup, M., Bue, M., Koch, J., Jensen, L. K., Hanberg, P., Aalbaek, B., Fuursted, K., Jensen, H. E. & Søballe, K., 2 Mar 2016, In: Journal of Bone and Joint Surgery: American Volume. 98, 5, p. 363-369 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cefuroxime 100%
  • Osteomyelitis 81%
  • Swine 59%
  • Pharmacokinetics 56%
  • Bone and Bones 44%
  20 Citations (Scopus)

• Infected bone tissue decreases the penetration of cefuroxime

  Tøttrup, M., Bue, M., Koch, J., Jensen, L. K., Hanberg, P., Aalbæk, B., Fuursted, K., Jensen, H. E. & Søballe, K., 2016.

  Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

• Novel marine biomolecules against biofilm – NOMORFILM

  Jensen, L. K. & Jensen, H. E., 2016.

  Research output: Contribution to conference › Poster › Research › peer-review
• 2015

  Specific antibodies to Staphylococcus aureus  biofilm are present in serum from pigs with osteomyelitis

  Jensen, L. K., Jensen, H. E., Koch, J., Bjarnsholt, T., Eickhardt-Dalbøge, S. R. & Shirtliff, M., 1 Sept 2015, In: In Vivo. 29, p. 555-560 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Serum Level 100%
  • Osteomyelitis 79%
  • Biofilms 71%
  • Staphylococcus aureus 63%
  • Antigen 61%
  10 Citations (Scopus)

  33 Downloads (Pure)

• Whole-genome sequence of Staphylococcus aureus S54F9 isolated from a chronic disseminated porcine lung abscess and used in human infection models

  Aalbæk, B., Jensen, L. K., Jensen, H. E., Olsen, J. E. & Christensen, H., 2015, In: Genome Announcements. 3, 5, 2 p., e01207-15.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lung Abscess 100%
  • Staphylococcus aureus 62%
  • Swine 57%
  • Genome 49%
  • Superantigens 47%
  12 Citations (Scopus)

  59 Downloads (Pure)
• 2014

  Fluorescence in situ hybridization for the tissue detection of bacterial pathogens associated with porcine infections.

  Jensen, H. E., Jensen, L. K., Barington, K., Pors, S. E., Bjarnsholt, T. & Boye, M., 15 Nov 2014, In: Methods in Molecular Biology. 1247, p. 219-134 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Fluorescence In Situ Hybridization 100%
  • Swine 78%
  • Peptide Nucleic Acids 58%
  • DNA Probes 47%
  • Infections 47%
  2 Citations (Scopus)

• Immunohistochemical detection of interleukin-8 in inflamed porcine tissues

  Laursen, H., Jensen, H. E., Leifsson, P. S., Jensen, L. K., Christiansen, J. K. G., Trebbien, R. & Nielsen, O. L., 15 May 2014, In: Veterinary Immunology and Immunopathology. 159, 1-2, p. 97-102 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • interleukin-8 100%
  • Interleukin-8 76%
  • neutrophils 75%
  • Swine 63%
  • Neutrophils 63%
  4 Citations (Scopus)

• Systemic inflammatory response and local cytokine expression in porcine models of endocarditis

  Christiansen, J. K. G., Jensen, H. E., Jensen, L. K., Koch, J., Aalbæk, B., Nielsen, O. L. & Leifsson, P. S., Apr 2014, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 122, 4, p. 292-300 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Endocarditis 100%
  • Swine 76%
  • Interleukin-8 65%
  • Cytokines 59%
  • Interleukin-1 54%
  8 Citations (Scopus)
• 2013

  Animal models of hematogenous Staphylococcus aureus osteomyelitis in long bones: a review

  Johansen, L. K. & Jensen, H. E., 2013, In: Orthopedic Research and Reviews. 5, p. 51-64 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Development, characterization and application of a porcine model for haematogenous ostemyelitis in children

  Jensen, L. K., 15 Nov 2013, Faculty of Health and Medical Sciences, University of Copenhagen. 114 p.

  Research output: Book/Report › Ph.D. thesis

• Development and characterization of porcine models of non-bacterial and staphylococcal endocarditis: histopathological aspects

  Christiansen, J. K. G., Jensen, H. E., Johansen, L. K., Koch, J., Koch, J., Aalbæk, B., Nielsen, O. L. & Leifsson, P. S., 2013, In: International Journal of Antimicrobial Agents. 41, Suppl. 1, p. 24-25 2 p., P60.

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

• Eksperimental Staphyloccocus aureus sepsis: Development of Metastatic Bone Lesions (pyemisa) in Pigs

  Jensen, L. K., 2013, Copenhagen University.

  Research output: Book/Report › Ph.D. thesis

• Embolic encephalitis in a porcine model of endocarditis

  Christiansen, J. K. G., Oscarson, M., Jensen, H. E., Johansen, L. K., Koch, J., Aalbæk, B., Nielsen, O. L., Iburg, T. M. & Leifsson, P. S., 2013, In: In Vivo. 27, 5, p. 591-597 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Thrombotic 100%
  • Encephalitis 69%
  • Endocarditis 67%
  • Swine 51%
  • Staphylococcus aureus 37%
  7 Citations (Scopus)

  903 Downloads (Pure)

• Experimental Porcine Endocarditis

  Christiansen, J. K. G., Jensen, H. E., Johansen, L. K., Koch, J., Aalbæk, B., Nielsen, O. L., Iburg, T. M. & Leifsson, P. S., 2013.

  Research output: Contribution to conference › Conference abstract for conference › Communication

• Functional characterization of a porcine emphysema model

  Bruun, C. V. S., Johansen, L. K., Leifsson, P. S., Nielsen, J., Cirera Salicio, S., Jørgensen, C. B., Jensen, H. E. & Fredholm, M., Dec 2013, In: Lung. 191, 6, p. 669-675 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Emphysema 100%
  • Swine 70%
  • Chronic Obstructive Pulmonary Disease 28%
  • mouse matrix metallopeptidase 12 17%
  • Lung 17%
  12 Citations (Scopus)

• Porcine models of non-bacterial thrombotic endocarditis (NBTE) and infective endocarditis (IE) caused by Staphylococcus aureus: a preliminary study

  Christiansen, J. K. G., Jensen, H. E., Johansen, L. K., Koch, J., Koch, J., Aalbæk, B., Nielsen, O. L. & Leifsson, P. S., May 2013, In: Journal of Heart Valve Disease. 22, p. 368-376 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Non-Infective Endocarditis 100%
  • Endocarditis 58%
  • Staphylococcus aureus 48%
  • Swine 44%
  • Blood Culture 11%
  9 Citations (Scopus)

• Therapy of haematogenous osteomyelitis: a comparative study in a porcine model and Angolan children

  Johansen, L. K., Koch, J., Kirketerp-Møller, K., Wamsler, O. J., Nielsen, O. L., Leifsson, P. S., Frees, D., Aalbæk, B. & Jensen, H. E., 2013, In: In Vivo. 27, 3, p. 305-312 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Osteomyelitis 100%
  • Swine 72%
  • Child 40%
  • Bone and Bones 31%
  • Application 28%
  6 Citations (Scopus)
• 2012

  A porcine model of heamatogenous osteomyelitis: pathogenesis and pathology

  Jensen, L. K., Koch, J., Frees, D., Aalbæk, B., Nielsen, O. L., Leifsson, P. S., Buelund, L. E., Svalastoga, E. L. & Jensen, H. E., 2012. 1 p.

  Research output: Contribution to conference › Poster › Research

• Expression of matrix metalloproteinase-9 and -12 in porcine lung infections

  Bruun, C. V. S., Leifsson, P. S., Johansen, L. K., Jensen, H. M. E., Nielsen, J. & Fredholm, M., Feb 2012, In: Journal of Comparative Pathology. 146, 2-3, p. 253-257 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  6 Citations (Scopus)

• Initiering, komparative aspekter og kødkontrolmæssig bedømmelse af osteomyelitis ved pyæmi

  Johansen, L. K. & Jensen, H. M. E., 2012. 2 p.

  Research output: Contribution to conference › Conference abstract for conference › Communication

• Local osteogenic expression of cyclooxygenase-2 and systemic response in porcine models of osteomyelitis

  Johansen, L. K., Iburg, T. M., Nielsen, O. L., Leifsson, P. S., Dahl-Pedersen, K., Koch, J., Frees, D., Aalbæk, B., Heegaard, P. M. H. & Jensen, H. M. E., Mar 2012, In: Prostaglandins & Other Lipid Mediators. 97, 3-4, p. 103-108 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Osteogenic 100%
  • Osteomyelitis 85%
  • Cyclooxygenase 2 82%
  • Swine 62%
  • Haptoglobins 33%
  6 Citations (Scopus)
• 2011

  A porcine model of acute, haematogenous, localized osteomyelitis due to Staphylococcus aureus: a pathomorphological study

  Johansen, L. K., Frees, D., Aalbæk, B., Koch, J., Iburg, T. M., Nielsen, O. L., Leifsson, P. S. & Jensen, H. M. E., Feb 2011, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 119, 2, p. 111-118 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  26 Citations (Scopus)

• Grisen som model for osteomyelitis: komparative terapeutiske aspekter

  Johansen, L. K., 2011, In: Dyrlaegemagasinet for Praktiserende Dyrlaeger. 4, p. 6-8 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Grise skal hjælpe mennesker med knoglemarvsbetændelse

  Johansen, L. K., 2011, In: Aktuel Naturvidenskab. 2, p. 38-40 3 p.

  Research output: Contribution to journal › Journal article › Research

• Pathology and biofilms in a porcine model of heamatogenous osteomyelitis

  Johansen, L. K., 2011.

  Research output: Contribution to conference › Conference abstract for conference › Research
• 2010

  A non-traumatic Staphylococcus aureus osteomyelistis model in pigs

  Jensen, H. M. E., Nielsen, O. L., Agerholm, J. S., Iburg, T. M., Johansen, L. K., Johannesson, E., Møller, M., Jahn, L., Munk, L., Aalbæk, B. & Leifsson, P. S., 2010, In: In Vivo. 24, p. 257-264 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Apoptotic 100%
  • Staphylococcus aureus 74%
  • Swine 68%
  • Plate Like Crystal 68%
  • Strain 60%
  38 Citations (Scopus)

• A porcine model of localized acute osteomyelitis due to Staphylococcus aureus

  Johansen, L. K., 2010. 2 p.

  Research output: Contribution to conference › Conference abstract for conference › Research

  9 Downloads (Pure)
• 2009

  A non-traumatic porcine model of acute staphylococcus aureus induced osteomyelitis

  Jensen, H. M. E., Nielsen, O. L., Aalbæk, B., Agerholm, J. S., Iburg, T. M., Johannesson, E., Møller, M., Johansen, L. K., Jahn, L., Munk, L. & Leifsson, P. S., 2009, Pathology today. p. 83 1 p.

  Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research

• Characterization of phenotypically similar murine and porcine models of human lung emphysema

  Bruun, C. V. S., Leifsson, P. S., Jensen, H. E., Jensen, L. K., Cirera Salicio, S., Jørgensen, C. B., Nielsen, J. & Fredholm, M., 2009. 1 p.

  Research output: Contribution to conference › Poster › Research