Kirstine Callø

2019

Acquired LQTS in horses

Callø, K., Trachsel, D. S., Rognant, S., Friis, S., Pedersen, P. J. & Klærke, D. A., 8 Aug 2019.

Research output: Contribution to conference › Poster › Communication

Cardiac repolarization in horses

Klærke, D. A., Trachsel, D. S., Buhl, R., Pedersen, P. J. & Callø, K., 8 Aug 2019.

Research output: Contribution to conference › Poster › Communication

Comparison of cultured human cardiomyocyte clusters obtained from embryos/fetuses or derived from human embryonic stem cells

Grubb, S. J., Vestergaard, M. L., Andersen, A. S., Rasmussen, K. K., Mamsen, L., Tuckute, G., Grunnet-Lauridsen, K., Møllgård, K., Ernst, E., Christensen, S. T., Calloe, K. & Andersen, C. Y., 1 May 2019, In: Stem Cells and Development. 28, 9, p. 608-619

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Compounds commonly used in equine medicine inhibits the voltage-gated potassium channel K _v 11.1

Calloe, K., Rognant, S., Friis, S., Shaughnessy, C., Klaerke, D. A. & Trachsel, D., 2019, In: Research in Veterinary Science. 123, p. 239-246 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Doctoral Dissertation: The transient outward potassium current in healthy and diseased hearts

Calloe, K., Jan 2019, In: Acta Physiologica. 225 , S717, e13225.

Research output: Contribution to journal › Journal article › Research › peer-review

PACAP-38 and PACAP(6-38) Degranulate Rat Meningeal Mast Cells via the Orphan MrgB₃-Receptor

Pedersen, S. H., la Cour, S. H., Calloe, K., Hauser, F., Olesen, J., Klaerke, D. A. & Jansen-Olesen, I., 29 Jan 2019, In: Frontiers in Cellular Neuroscience. 13, 11 p., 114.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

11 Downloads (Pure)

Purification of Functional Human TRP Channels Recombinantly Produced in Yeast

Zhang, L., Wang, K., Klaerke, D. A., Calloe, K., Lowrey, L., Pedersen, P. A., Gourdon, P. & Gotfryd, K., Feb 2019, In: Cells. 8, 2, p. 1-20 148.

Research output: Contribution to journal › Journal article › Research › peer-review

43 Downloads (Pure)

Structure of the human ClC-1 chloride channel

Wang, K., Preisler, S. S., Zhang, L., Cui, Y., Missel, J. W., Grønberg, C., Gotfryd, K., Lindahl, E., Andersson, M., Calloe, K., Egea, P. F., Klaerke, D. A., Pusch, M., Pedersen, P. A., Zhou, Z. H. & Gourdon, P., 2019, In: PLOS Biology. 17, 4, p. 1-20 e3000218.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

38 Downloads (Pure)

The Transient Outward Potassium Current in Healthy and Diseased Hearts

Callø, K., 2019, Københavns Universitet.

Research output: Book/Report › Doctoral thesis

2018

Effects of trimethoprim–sulfadiazine and detomidine on the function of equine K_v11.1 channels in a two-electrode voltage-clamp (TEVC) oocyte model

Trachsel, D. S., Tejada, M. A., Groesfjeld Christensen, V., Pedersen, P. J., Kanters, J. K., Buhl, R., Calloe, K. & Klaerke, D. A., 2018, In: Journal of Veterinary Pharmacology and Therapeutics. 41, 4, p. 536-545 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

57 Downloads (Pure)

Interventricular differences in sodium current and its potential role in Brugada syndrome

Calloe, K., Aistrup, G. L., Di Diego, J. M., Goodrow, R. J., Treat, J. A. & Cordeiro, J. M., 2018, In: Physiological Reports. 6, 14, 12 p., e13787.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

48 Downloads (Pure)

Multifocal atrial and ventricular premature contractions with an increased risk of dilated cardiomyopathy caused by a Na_v1.5 gain-of-function mutation (G213D)

Calloe, K., Broendberg, A. K., Christensen, A. H., Pedersen, L. N., Olesen, M. S., de Los Angeles Tejada, M., Friis, S., Thomsen, M. B., Bundgaard, H. & Jensen, H. K., 15 Apr 2018, In: International Journal of Cardiology. 257, p. 160-167 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Reconstitution and Electrophysiological Characterization of Ion Channels in Lipid Bilayers

Klærke, D. A., Tejada, M. D. L. A., Christensen, V. G., Lassen, M., Pedersen, P. A. & Callø, K., Jun 2018, In: Current Protocols in Pharmacology. 81, 1, p. e37 17 p., e37.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

2017

Heteromeric Slick/Slack K⁺ channels show graded sensitivity to cell volume changes

Tejada, M. A., Hashem, N., Callø, K. & Klaerke, D. A., Feb 2017, In: PLOS ONE. 12, 2, 11 p., e0169914.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

59 Downloads (Pure)

Human embryonic stem cell derived cardiomyocytes self-arrange with areas of different subtypes during differentiation

Vestergaard, M. L., Grubb, S., Rasmussen, K. K., Anderson-Jenkins, Z. L., Grunnet-Lauridsen, K., Callø, K., Clausen, C., Christensen, S. T., Møllgård, K. & Andersen, C. Y., 1 Nov 2017, In: Stem Cells and Development. 26, 21, p. 1566-1577 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Molecular cloning and functional expression of the K⁺ channel K_V7.1 and the regulatory subunit KCNE1 from equine myocardium

Pedersen, P. J., Thomsen, K. B., Flak, J. B., Tejada, M. D. L. A., Hauser, F., Trachsel, D. S., Buhl, R., Kalbfleisch, T., DePriest, M. S., MacLeod, J. N., Callø, K. & Klærke, D. A., Aug 2017, In: Research in Veterinary Science. 113, p. 79-86 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B

Zhang, Y., Schmid, B., Nikolaisen, N. K., Rasmussen, M. A., Garcia, B. I. A., Agger, M., Callø, K., Stummann, T. C., Larsen, H. M., Nielsen, T. T., Huang, J., Xu, F., Liu, X., Bolund, L., Meyer, M., Bak, L. K., Waagepetersen, H. S., Luo, Y., Nielsen, J. E. & Consortium, T. F. & 4 others, Holst, B., Clausen, C., Hyttel, P. & Freude, K., 14 Mar 2017, In: Stem Cell Reports. 8, 3, p. 648-658

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

471 Downloads (Pure)

Single-Channel Recordings of K⁺ Channels Expressed in Saccharomyces Cerevisiae

Tejada, M. D. L. A., Molbaek, K., Cazimi, H., Ellekvist, P., Callø, K., Nielsen, C. H., Pedersen, P. A. & Klærke, D. A., 2017, In: Biophysical Journal. 112, 3, Suppl. 1, p. 406A 1 p., 2002-Pos Board B322.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Ventricular repolarization time, location of pacing stimulus and current pulse amplitude conspire to determine arrhythmogenicity in mice

Speerschneider, T., Grubb, S. J., Olesen, S. P., Calloe, K. & Thomsen, M. B., 1 Mar 2017, In: Acta Physiologica. 219, 3, p. 662-670 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

2016

A dual potassium channel activator improves repolarization reserve and normalizes ventricular action potentials

Calloe, K., Di Diego, J. M., Hansen, R. S., Nagle, S. A., Treat, J. A. & Cordeiro, J. M., 15 May 2016, In: Biochemical Pharmacology. 108, p. 36-46 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Human atrial fibroblasts and their contribution to supraventricular arrhythmia

Thomsen, M. B. & Calloe, K., Feb 2016, In: Physiological Reports. 4, 3, 3 p., e12711.

Research output: Contribution to journal › Editorial › peer-review

4 Citations (Scopus)

Physiological roles of the transient outward current I_to in normal and diseased hearts

Cordeiro, J. M., Callø, K., Aschar-Sobbi, R., Kim, K.-H., Korogyi, A., Occhipinti, D., Backx, P. H. & Panama, B. K., 1 Jan 2016, In: Frontiers in bioscience (Scholar edition). 8, p. 143-159 17 p., 454.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

2015

Action potential repolarization in equine hearts

Callø, K., Pedersen, P. J., Tejada, M. D. L. A., Poulsen, K. L., Grubb, S. J., Buhl, R. & Klærke, D. A., 2015, In: Biophysical Journal. 108, 2, Supplement 1, p. 113a 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

Axelsen, L. N., Callø, K., Braunstein, T. H., Riemann, M., Hofgaard, J. P., Liang, B., Jensen, C. F., Olsen, K. B., Bartels, E. D., Baandrup, U., Jespersen, T., Nielsen, L. B., von Holstein-Rathlou, N.-H. & Nielsen, M. S., 14 Jul 2015, In: Cardiovascular Diabetology. 14, 14 p., 87.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

185 Downloads (Pure)

High incidence of functional ion-channel abnormalities in a consecutive Long QT cohort with novel missense genetic variants of unknown significance

Steffensen, A. B., Refaat, M. M., David, J.-P., Mujezinovic, A., Calloe, K., Wojciak, J., Nussbaum, R. L., Scheinman, M. M. & Schmitt, N., 12 Jun 2015, In: Scientific Reports. 5, p. 1-13 13 p., 10009.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Molecular cloning and functional expression of the Equine K+ channel KV11.1 (Ether à Go-Go-related/KCNH2 gene) and the regulatory subunit KCNE2 from equine myocardium

Pedersen, P. J., Thomsen, K. B., Olander, E. R., Hauser, F., Tejada, M. D. L. A., Poulsen, K. L., Grubb, S. J., Buhl, R., Callø, K. & Klærke, D. A., 16 Sept 2015, In: PloS one. 10, 9, 19 p., e0138320.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

144 Downloads (Pure)

Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2

Grubb, S. J., Aistrup, G. L., Koivumäki, J. T., Speerschneider, T., Gottlieb, L. A., Mutsaers, N. A. M., Olesen, S.-P., Callø, K. & Thomsen, M. B., 1 Aug 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 309, 3, p. H481-H489 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

The Mutation P.T613a in the Pore Helix of the Kv 11.1 Potassium Channel is Associated with Long Qt Syndrome

Poulsen, K. L., Hotait, M., Calloe, K., Klaerke, D. A., Rebeiz, A., Nemer, G., Tejada, M. A. & Refaat, M. M., Nov 2015, In: Pacing and Clinical Electrophysiology. 38, 11, p. 1304–1309 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

2014

Activation, Permeability, and Inhibition of Astrocytic and Neuronal Large Pore (Hemi)channels

Hansen, D. B., Ye, Z.-C., Calloe, K., Braunstein, T. H., Hofgaard, J. P., Ransom, B. R., Nielsen, M. S. & MacAulay, N., 19 Sept 2014, In: The Journal of Biological Chemistry. 289, 38, p. 26058-73 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

Loss of K⁺ currents in heart failure is accentuated in KChIP2 deficient mice

Grubb, S. J., Speerschneider, T., Occhipinti, D., Fiset, C., Olesen, S.-P., Thomsen, M. B. & Callø, K., Aug 2014, In: Journal of Cardiovascular Electrophysiology. 25, 8, p. 896-904 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

NS5806 partially restores action potential duration but fails to ameliorate calcium transient dysfunction in a computational model of canine heart failure

Maleckar, M. M., Lines, G. T., Koivumäki, J. T., Cordeiro, J. M. & Callø, K., Nov 2014, In: Europace. 16, suppl. 4, p. iv46-iv55 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

2013

A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation

Olesen, M. S. S., Refsgaard, L., Holst, A. G., Larsen, A. P., Grubb, S., Haunsø, S., Svendsen, J. H., Olesen, S.-P., Schmitt, N. & Callø, K., 1 Jun 2013, In: Cardiovascular Research. 98, 3, p. 488-495 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

73 Citations (Scopus)

1 Downloads (Pure)

Characterization and mechanisms of action of novel Na_V1.5 channel mutations associated with Brugada syndrome

Callø, K., Refaat, M. M., Grubb, S., Wojciak, J., Campagna, J., Thomsen, N. M., Nussbaum, R. L., Scheinman, M. M. & Schmitt, N., Feb 2013, In: Circulation. Arrhythmia and Electrophysiology (Online). 6, 1, p. 177-184 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

1337 Downloads (Pure)

Development of heart failure is independent of K+ channel-interacting protein 2 expression

Speerschneider, T., Grubb, S., Metoska, A., Olesen, S.-P., Callø, K. & Thomsen, M. B., 1 Dec 2013, In: Journal of Physiology. 591, 23, p. 5923-37 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Dysfunction of the heteromeric K_V7.3/K_V7.5 potassium channel is associated with autism spectrum disorders

Nielsen, M. G., Rasmussen, H. B., Callø, K., F. Sequeira, A., Baretto, M., Oliveira, G., Almeida, J., B. Lauritsen, M., Ullmann, R., Boonen, S. E., Brøndum-Nielsen, K., M. Kalscheuer, V., Tümer, Z., M. Vicente, A., Schmitt, N. & Tommerup, N., 2013, In: Frontiers in Genetics. 4, 54, p. 1-13 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

2451 Downloads (Pure)

Gliadin Fragments and a Specific Gliadin 33-mer Peptide Close KATP Channels and Induce Insulin Secretion in INS-1E Cells and Rat Islets of Langerhans

Dall, M., Calloe, K., Haupt-Jorgensen, M., Larsen, J., Schmitt, N., Josefsen, K. & Buschard, K., 13 Jun 2013, In: PLOS ONE. 8, 6, p. 1-10 10 p., e66474.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Managing the complexity of communication: regulation of gap junctions by post-translational modification

Axelsen, L. N., Callø, K., von Holstein-Rathlou, N.-H. & Nielsen, M. S., Oct 2013, In: Frontiers in Pharmacology. 4, p. 1-18 18 p., 130.

Research output: Contribution to journal › Journal article › Research › peer-review

Tissue-specific effects of acetylcholine in the canine heart

Callø, K., Goodrow, R., Olesen, S.-P., Antzelevitch, C. & Cordeiro, J. M., 1 Jul 2013, In: A J P: Heart and Circulatory Physiology (Online). 305, p. H66-H75 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

1646 Downloads (Pure)

2012

Impact of KChIP2 on Cardiac Electrophysiology and the Progression of Heart Failure

Grubb, S., Callø, K. & Thomsen, M. B., 2012, In: Frontiers in Physiology. 3, p. 118

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Physiological consequences of transient outward K(+) current activation during heart failure in the canine left ventricle

Cordeiro, J. M., Callø, K., Moise, N. S., Kornreich, B., Giannandrea, D., Di Diego, J. M., Olesen, S.-P. & Antzelevitch, C., Jun 2012, In: Journal of Molecular and Cellular Cardiology. 52, 6, p. 1291-8 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

2011

A Novel Nonsense Variant in Nav1.5 Cofactor MOG1 Eliminates Its Sodium Current Increasing Effect and May Increase the Risk of Arrhythmias

Olesen, M. S., Jensen, N. F., Holst, A. G., Nielsen, J. B., Tfelt-Hansen, J., Jespersen, T., Sajadieh, A., Haunsø, S., Lund, J. T., Calloe, K., Schmitt, N. & Svendsen, J. H., 26 May 2011, In: Canadian Journal of Cardiology. 27, 4, p. 523.e17-23

Research output: Contribution to journal › Journal article › Research › peer-review

42 Citations (Scopus)

Comparison of the Effects of a Transient Outward Potassium Channel Activator on Currents Recorded from Atrial and Ventricular Cardiomyocytes.

Callø, K., Nof, E., Jespersen, T., Di Diego, J. M., Chlus, N., Olesen, S.-P., Antzelevitch, C. & Cordeiro, J. M., Sept 2011, In: Journal of Cardiovascular Electrophysiology. 22, 9, p. 1057-1066 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

Multiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5A

Calloe, K., Schmitt, N., Grubb, S., Pfeiffer, R., David, J.-P., Kanter, R., Cordeiro, J. M., Antzelevitch, C. & Callø, K., Oct 2011, In: Canadian Journal of Physiology and Pharmacology. 89, 10, p. 723-36 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

2010

A common single nucleotide polymorphism can exacerbate long-QT type 2 syndrome leading to sudden infant death

Nof, E., Cordeiro, J. M., Pérez, G. J., Scornik, F. S., Calloe, K., Love, B., Burashnikov, E., Caceres, G., Gunsburg, M. & Antzelevitch, C., Apr 2010, In: Circulation. Cardiovascular genetics. 3, 2, p. 199-206 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

41 Citations (Scopus)

2009

Accelerated inactivation of the L-type calcium current due to a mutation in CACNB2b underlies Brugada syndrome

Cordeiro, J. M., Marieb, M., Pfeiffer, R., Calloe, K., Burashnikov, E. & Antzelevitch, C., 2009, In: Journal of Molecular and Cellular Cardiology. 46, 5, p. 695-703 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

76 Citations (Scopus)

A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease

Holst, A. G., Calloe, K., Jespersen, T., Cedergreen, P., Winkel, B. G., Jensen, H. K., Leren, T. P., Haunso, S., Svendsen, J. H. & Tfelt-Hansen, J., 2009, In: Case Reports in Medicine. 2009, p. 963645

Research output: Contribution to journal › Journal article › Research › peer-review

Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

Calloe, K., Soltysinska, E., Jespersen, T., Lundby, A., Antzelevitch, C., Olesen, S.-P. & Cordeiro, J. M., 2009, In: Journal of Molecular and Cellular Cardiology. 48, 1, p. 191-200 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

37 Citations (Scopus)

Functional properties of human neuronal Kv11 channels

Einarsen, K., Calloe, K., Grunnet, M., Olesen, S.-P. & Schmitt, N., 2009, In: Pflügers Archiv: European Journal of Physiology. 458, 4, p. 689-700 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

2008

A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome

Calloe, K., Cordeiro, J. M., Di Diego, J. M., Hansen, R. S., Grunnet, M., Olesen, S. P. & Antzelevitch, C., 2008, In: Cardiovascular Research. 81, 4, p. 686-94 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

83 Citations (Scopus)

2007

Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.

Calloe, K., Ravn, L. S., Schmitt, N., Sui, J. L., Duno, M., Haunso, S., Grunnet, M., Svendsen, J. H. & Olesen, S.-P., 2007, In: Biochemical and Biophysical Research Communications. 364, 4, p. 889-95 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

Kirstine Callø

Research output

Search results