Personal profile

Primary fields of research

My research is focused on the impact of mutations, molecular regulatory mechanisms and accessory subunits on the function of ion channel complexes.
My research aims at understanding mechanisms leading to ion channel diseases. To this end, I study the function of ion channels in the cellular context, i.e. I address (i) how these proteins work, (ii) how they exert their physiological role at the correct place with the right interaction partners, (iii) how they are regulated, and (iv) how they can be (pharmacologically) manipulated.

  • Structure/function analysis of voltage-gated potassium channels
  • Molecular basis of channelopathies
  • Elucidation of protein-protein interactions within macromolecular channel protein complexes
  • Methodical focus on molecular biology and protein-biochemistry

Fields of interest

  • Physiology of ion channel complexes
  • Academic and organisational leadership
  • Education
  • Mentoring
  • Research Data Management
  • Public outreach

Possible conflicts of interest

None

Teaching

  • Main supervisor of undergraduate and graduate students
  • Supervisor of PhD projects
  • Lectures, classroom teaching and courses at undergraduate and graduate level in the study courses Medicine, Molecular Biomedicine, Odontology, Human Biology, Biology, Medicine & Technology, Public Health, Quantitative Modelling of Biologial Systems, Health Informatics
  • Organizer of several PhD courses

For more details, have a look at Nicole Schmitt's presentation of teaching activities at the Department of Biomedical Sciences

 

CV

Curriculum vitae | Nicole Schmitt, PhD, professor

Email | Website | Orcid | ResearcherID

Research positions and academic qualifications

2017 onwards

Professor with special responsibilities within Blended Learning and Engagement in Education at the Dept. of Biomedical Sciences, SUND, UCPH

2012 - 2017

Associate professor – tenured – at BMI, SUND, UCPH

2011 - 2012

Junior Group Leader at BMI, SUND, UCPH

2009 – 2012

Associate Professor (Danish title: lektor) - non-tenured - at the Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), SUND, UCPH

2005 – 2009

Associate Research Professor (Danish title: forskningslektor), DARC, SUND, UCPH

2002 – 2005

Assistant Professor (Danish title: adjunkt), Dept. of Medical Physiology, SUND, UCPH

2000 – 2002

Post.doc in Prof. Olaf Pongs’ laboratory, Institute of Neuronal Signal Transduction, Centre of Molecular Neurobiology, Hamburg, Germany

Education and training

1997 – 2000

PhD (Dr. rer. nat.) at the University of Hamburg, Germany

1990 – 1996

MSc in Biochemistry at the University of Hannover, Germany

Formal leadership

2016 onwards

Vice Head of Department for Education at the Dept. of Biomedical Sciences
I am responsible for building a sustainable teaching framework to secure quality of education. Amongst others, my activities comprise organizing workshops for peers, postdocs and PhD students to share experiences and identify best practice, reviewing course evaluations and budgets, reviewing and monitoring teaching activities, and teacher recruitment.

2015 onwards

Member of the Department’s Leadership Team (ILT)
My activities include, amongst others, advising the Head of Department, partaking in departmental strategy planning and development of action plans.

2015 - 2017

Section manager of the Heart & Circulatory research section at the Dept. of Biomedical Sciences (section structure at department discontinued in April 2017)

2011 onwards

Group leader (varying group size, 4-10 scientific and technical personnel).
Through engaged research management, I ensure that my research group is active with regards to research, academic visibility, teaching, and fund raising. I safeguard my group members’ adherence to rules and guidelines for work environment and scientific integrity. I am responsible for the personal and professional development of my staff and conduct annual performance and development reviews.

2008 -2017

Daily leader of the Ion Channel Group (cluster of several senior scientists)

Academic citizenship -  committees, councils, and boards

2019 onwards

 

Member of Steering Group for a new study administration platform
appointed by the Pro-Rector for Education at UCPH

2019 onwards

 

Member of “UCPH Steering Group for Information Security”
- appointed  by the Rector of UCPH -  

2016 onwards

Department representative in the Educational Councils for Medicine and Public Health (Uddannelsesråd for Sundhed og Medicin, Uddannelsesråd for Folkesundhedsvidenskaberne)

2015 onwards

UCPH representative in the National Forum for Research Data Management

2015 onwards

Faculty representative  in UCPH reference group for data management
appointed by the Vice-Dean for Research at SUND

2015 – 2016

Chairperson of TASK FORCE Data Management as per the Danish Code of Conduct for Research Integrity at SUND
The task force delivered the SUND policy for data management,an implementation plan/road map, and recommendations for introduction of an Electronic Laboratory Notebook at the Faculty

2013 – 2015

Co-chair - elected - of the Department Council (Institutråd) of the Dept. of Biomedical Sciences
The Council was the driving force behind the implementation of faculty strategy at departmental level. The Council had the responsibility to ensure integration of employees and students in the decision making process.

2012 – 2018

Scientific board member of the SUND seminar series “World Experts in Health and Medical Sciences” at the Faculty of Health and Medical Sciences
Faculty spanning seminar series to support academic development in students as well as creating cross-sector collaborations, discontinued in Dec 2018.

Awards

  • Fondsbørsvekselerer Henry Hansen og Hustrus Award 2012
    Project: “Pathogenesis and treatment of atrial fibrillation"

  • Gerda and Aage Haensch Award 2012
    Project: “Patient-specific pluripotent stem cell models for atrial fibrillation"

Research supervision and mentoring

  • Supervisor of postdoctoral researchers

  • Supervisor of PhD projects

  • Mentor in UCPH mentor programme for assistant professors (2007, 2016 onwards) and postdocs (2019 onwards)

  • Member of Steering committee for the Mentor Programme for Postdocs at SUND, 2019 onwards

  • Evaluation and assessment of PhD theses and chairperson of PhD assessment committees

Innovation

Steering Committee Member of the Innovation Fund Denmark project “Safe and effective pharmacological treatment for atrial fibrillation” (2014 - 2018)
Joined drug discovery program of the Ion Channel Group, UCPH, and the biotech company Acesion Pharma, financed by The Danish National Advanced Technology Foundation (now Innovation Fund Denmark)

Outreach and dissemination

  • Co-organizer of a “Health Market” (“Sundhedsmarkedsdag) under the Municipality Copenhagen (Lokaludvalg Amager Øst) (Sep 2019)

  • Speaker in the series ”Talks på toppen” (Talks at the top) at the Faculty (Feb 2019)
    "Den bedste behandling mod bankende hjerter"

  • Workshops within the topic human biology for talented high school students (Akademi for Talentfulde Unge)

  • Performance at the Copenhagen Culture Night 2018
    Featured activity, art & science performance combining retro-futuristic compositions, visuals, and science about the miracles of the heart with band Detekt and visual artists Rathschau & Lisboa

  • Participation (speaker) at the FROST festival in Copenhagen 2018
    (“Puls”, experience that blends science and art)

  • Organisation and execution of exhibition and activities at the Copenhagen Culture Night 2017
    “This is the rhythm of my heart"

  • Several roles in the Faculty’s contribution - IND I KROPPEN – at the “Science in the City” Festival in connection with the EuroScience Open Forum 2014 conference:(i) Member of scientific committee for science slam and exhibition activities,(ii) Host for two science slams about the heart and cardiac function (“Mit hjerte slår på en helt ny måde”, “Beatet i dit hjerte”),(iii) Science slam speaker

 Academic services

  • Research evaluation of the University of Gothenburg (Research Evaluation for Development 2019 – RED19)

  • Reviewer of research proposals (grants and positions)
    e.g. Volkswagen Stiftung, Germany; Israel Science Foundation, Israel; Swiss Science Foundation, Switzerland; University of Leuven, Belgium

  • Invited member of the Abstract Reviewing Committee for the European Society of Cardiology Congress (2018 onwards) and European Heart Rhythm Association Meeting 2019

  • Assessor/chair of committee for positions at professor level at UCPH

  • Editorial Board member of “Reviews of Physiology, Biochemistry & Pharmacology” (from Nov 2018)

  • Reviewer of research articles
    e.g. Basic & Clinical Pharmacology & Toxicology; Cellular and Biochemical Physiology; FEBS Journal (European Journal of Biochemistry); European Heart Journal; Heart Rhythm Journal; Journal of Molecular and Cellular Cardiology; Journal of Physiology; Scientific Reports

Conference organization

  • Member of the Local Organizing Committee for Europhysiology 2022, Copenhagen
    (Joint meeting of The Physiological Society, the Scandinavian Physiological Society, the Deutsche Physiologische Gesellschaft, and the Federation of European Physiological Societies, expected ca. 2000 participants)

  • Invited member of the Organizing Committee of the Europhysiology conference series (2017-2022)

  • Co-organizer of the Copenhagen Meeting on Cardiac Arrhythmia 2014 and 2017 (200 participants)

  • Organization of the annual Ion Channel Symposium The Danish Royal Academy of Sciences and Letters, Copenhagen, Denmark, 2007 onwards (80-100 participants)

  • Co-chair of the Local Organizing Committee of “ScanGerman”,the 2010 Joint Meeting of the Scandinavian and German Physiological Societies, Copenhagen, Denmark (ca. 1000 participants)

International recognition - selected invited talks and chairmanships

2019

  • EHRA Congress - European Heart Rhythm Association, Lisbon, Portugal

2017

  • ESC Congress - European Society of Cardiology, Barcelona, Spain
  • FASEB Summer Research Conference “Ion Channel Regulation”, Colorado, USA
  • 42nd International School of Biophysics, Erice, Sicily, Italy
  • University of California San Francisco Medical Center, CA, USA

2015

  • National Center of Competence in Research TransCure at the University of Bern, Switzerland
  • FASEB Summer Research Conference “Ion Channel Regulation”, Big Sky, Montana, USA
  • “Colloquia in Cellular Physiology” at the Medical University Vienna, Austria

2014

  • Scientific Sessions of the American Heart Association, Chicago, IL, USA
  • University of California San Francisco Medical Center, CA, USA
  • University of California Irvine at the Dept. for Biological Sciences, CA, USA 
  • Invited Chair of a Session “Ion Channels” at the 4th Sigtuna Meeting of the Membrane Transport Group of the Scandinavian Physiological Society, Sigtuna Stiftelsen, Sweden
  • Chair (and organizer) of a Session “New physiological roles for known transmembrane proteins” at the Annual Meeting of the Scandinavian Physiological Society, Stockholm, Sweden

2013

  • Conference “Heidelberg Channels 2013”, University of Heidelberg, Germany
  • Invited Chair of Session “Channels and Transporters” at the 9th European Biophysics Congress EBSA, Lisbon, Portugal
  • FASEB Summer Research Conference “Ion Channel Regulation”, Nassau, Bahamas
  • 45th Meeting on Membrane Transport, Sandbjerg Manor, Sønderborg, Denmark
  • Deutsche Klinik für Diagnostik, Wiesbaden, Germany
  • “Ion Channels Conference”, Jämtland, Sweden

2012

  • Gordon Research Conference "Ion channels", South Hadley, MA, USA

Knowledge of languages

  • German (mother tongue)
  • English (fluent)
  • Danish (fluent)
  • French (basic)

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

PhD thesis “Structure/Function analyses of the human KvLQT1 potassium channel” (in German), University of Hamburg

19972000

Award Date: 18 Jul 2000

Master thesis "Characterization of a human cardiac potassium channel” (in German), University of Hannover

19901996

Award Date: 4 Nov 1996

Keywords

  • Faculty of Health and Medical Sciences
  • Ion Channel Group
  • Danish Arrhythmia Research Centre

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