Research output per year
Research output per year
Personal profile
CV
Professional qualifications:Cand. Scient. (Chemistry)
University Freiburg, Germany, 1989
Ph. D. (Biochemistry, Dr. rer. nat.)
University Munich, Germany, 1992
Prev. employment:
1997-2002
Laboratory Head
Department of Molecular Genetics,
H. Lundbeck A/S, Valby, Denmark
1995-97
Assistant Professor,
Department of Cell Biology and Anatomy,
Zoological Institute,
University Copenhagen, Denmark
1994-95
Guest researcher,
Department of Cell Biology and Anatomy,
Zoological Institute,
University Copenhagen, Denmark
1993-94
Postdoc,
Institute for Cell Biochemistry and
Clinical Neurobiology,
University Hamburg, Germany
1992-93
Postdoc,
Department of Neurochemistry,
Max-Planck-Institute for Psychiatry,
Martinsried, Germany
Prize: Otto-Hahn medal of the Max-Planck Society.
Current research
I'm interested in all aspects of molecular neurobiology with a special focus on G protein-coupled receptors and their signal transduction. My current research is concentrating on insect endocrinology. We identify, clone and express new "orphan" GPCRs from the fruit fly Drosophila melanogaster and other insects in different cell lines and identify their endogenous ligands (e.g. new neuropeptides or hormones) using promiscous or chimeric G-proteins and bioluminescence assays to monitor cellular responses. Thereby, we discover new ligand-receptor pairs regulating development, reproduction or behavior of insects.
A second line of my research interest are the identification and characterization of new neuropeptides and their processing enzymes in lower invertebrates, e.g. in Hydra or sea anemones.
Keywords
- Faculty of Science
- neurobiology
- neuropeptids
- G protein-coupled receptors
- insects
- endocrinology
- cell signalling
- bioinformatics
- gene annotation
- functional genomics
- cell biology
- functional assay
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De novo transcriptome assembly of the cubomedusa Tripedalia cystophora, including the analysis of a set of genes involved in peptidergic neurotransmission
Nielsen, S. K. D., Koch, T. L., Hauser, F., Garm, A. & Grimmelikhuijzen, C. J. P., 2019, In: BMC Genomics. 20, p. 1-20 20 p., 175.Research output: Contribution to journal › Journal article › Research › peer-review
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PACAP-38 and PACAP(6-38) Degranulate Rat Meningeal Mast Cells via the Orphan MrgB3-Receptor
Pedersen, S. H., la Cour, S. H., Calloe, K., Hauser, F., Olesen, J., Klaerke, D. A. & Jansen-Olesen, I., 29 Jan 2019, In: Frontiers in Cellular Neuroscience. 13, 11 p., 114.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional characterization of mosquito short neuropeptide F receptors
Christ, P., Hill, S. R., Schachtner, J., Hauser, F. & Ignell, R., May 2018, In: Peptides. 103, p. 31-39 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional characterization of the dual allatostatin-A receptors in mosquitoes
Christ, P., Hill, S. R., Schachtner, J., Hauser, F. & Ignell, R., Jan 2018, In: Peptides. 99, p. 44-55 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Feeding-induced changes in allatostatin-A and short neuropeptide F in the antennal lobes affect odor-mediated host seeking in the yellow fever mosquito, Aedes aegypti
Christ, P., Reifenrath, A., Kahnt, J., Hauser, F., Hill, S. R., Schachtner, J. & Ignell, R., 22 Nov 2017, In: PLoS ONE. 12, 11, 15 p., e0188243.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular cloning and functional expression of the K+ channel KV7.1 and the regulatory subunit KCNE1 from equine myocardium
Pedersen, P. J., Thomsen, K. B., Flak, J. B., Tejada, M. D. L. A., Hauser, F., Trachsel, D. S., Buhl, R., Kalbfleisch, T., DePriest, M. S., MacLeod, J. N., Callø, K. & Klærke, D. A., Aug 2017, In: Research in Veterinary Science. 113, p. 79-86 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adipokinetic hormones and their G protein-coupled receptors emerged in Lophotrochozoa
Li, S., Hauser, F., Skadborg, S. K., Nielsen, S. V., Kirketerp-Møller, N. & Grimmelikhuijzen, C., 15 Sept 2016, In: Scientific Reports. 6, 13 p., 32789.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomic insights into the Ixodes scapularis tick vector of Lyme disease
Gulia-Nuss, M., Nuss, A. B., Meyer, J. M., Sonenshine, D. E., Roe, R. M., Waterhouse, R. M., Sattelle, D. B., de la Fuente, J., Ribeiro, J. M., Megy, K., Thimmapuram, J., Miller, J. R., Walenz, B. P., Koren, S., Hostetler, J. B., Thiagarajan, M., Joardar, V. S., Hannick, L. I., Bidwell, S., Hammond, M. P., & 73 others, 9 Feb 2016, In: Nature Communications. 7, 13 p., 10507.Research output: Contribution to journal › Journal article › Research › peer-review