Research output per year
Research output per year
Personal profile
Short presentation
My current research interests are induced pluipotent cells (iPSC) from pigs and humans.
Regarding the porcine iPSC I am working on making naive pluripotent stem cells which are able to generate chimeras. Furthermore, I am comparing the pluripotent state of porcine iPSC to porcine embryos via RNAseq to understand similarities and discrepancies in regards to pluripotency.
I am interested in neurodegenerative disorder in particular Alzheimer's disease and frontotemporal dementia. I am using patient specific iPSC and differentiate these into disease relevant neuronal subtypes to investigate the underlying disaese mechanisms.
Keywords
- Faculty of Science
- Induced Pluripotent Stem Cells (iPSC)
- Neurodegenerative diseases
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Dive into the research topics where Kristine Freude is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Research output
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Cell type specific expression of toll-like receptors in human brains and implications in Alzheimer's disease
Frederiksen, H. R., Haukedal, H. & Freude, K., 2019, In: BioMed Research International. 2019, 18 p., 7420189.Research output: Contribution to journal › Review › peer-review
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Dementia, Brain Disorders and Molecular Mechanisms
Freude, K. & Krauss, S., 19 Apr 2019, In: Journal of Molecular Biology. 431, 9, p. 1709-1710Research output: Contribution to journal › Editorial
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Generation of two iPSC lines with either a heterozygous V717I or a heterozygous KM670/671NL mutation in the APP gene
Frederiksen, H. R., Holst, B., Ramakrishna, S., Muddashetty, R., Schmid, B. & Freude, K., 1 Jan 2019, In: Stem Cell Research. 34, 5 p., 101368.Research output: Contribution to journal › Journal article › Research › peer-review
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Generation of two isogenic iPSC lines with either a heterozygous or a homozygous E280A mutation in the PSEN1 gene.
Frederiksen, H. R. S., Holst, B., Mau-Holzmann, U. A., Freude, K. & Schmid, B., Mar 2019, In: Stem Cell Research. 35, 4 p., 101403.Research output: Contribution to journal › Journal article › Research › peer-review
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Implications of Microglia in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Haukedal, H. & Freude, K., 19 Apr 2019, In: Journal of Molecular Biology. 431, 9, p. 1818-1829Research output: Contribution to journal › Review › peer-review
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Induced pluripotent stem cells throughout the animal kingdom: Availability and applications
Pessôa, L. V. D. F., Bressan, F. F. & Freude, K. K., 2019, In: World Journal of Stem Cells. 11, 8, p. 491-505 15 p.Research output: Contribution to journal › Review › peer-review
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Modelling the neuropathology of lysosomal storage disorders through disease-specific human induced pluripotent stem cells
Kobolák, J., Molnár, K., Varga, E., Bock, I., Jezsó, B., Téglási, A., Zhou, S., Lo Giudice, M., Hoogeveen-Westerveld, M., Pijnappel, W. P., Phanthong, P., Varga, N., Kitiyanant, N., Freude, K., Nakanishi, H., László, L., Hyttel, P. & Dinnyés, A., 2019, In: Experimental Cell Research. 380, 2, p. 216-233 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oocytes, embryos and pluripotent stem cells from a biomedical perspective
Hyttel, P., Pessôa, L. V. D. F., Secher, J. B. M., Dittlau, K. S., Freude, K., Hall, V. J., Fair, T., Assey, R. J., Laurincik, J., Callesen, H., Greve, T. & Stroebech, L. B., 2019, In: Animal Reproduction. 16, 3, p. 508-523 16 p.Research output: Contribution to journal › Journal article › Research › peer-review