Research output per year
Research output per year
Personal profile
Primary fields of research
- Computational chemical design of tool compounds for the evaluation of the pharmacological potential of lactate and ketone metabolite receptors
- Virtual ligand screening for novel allosteric modulators for the free fatty-acid receptor GPR40
Teaching
MSc course for human biologists "Molecular Pharmacology"
Education/Academic qualification
Investigation of Structure-Function Relationships Within the Ghrelin Receptor Family, Faculty of Science, University of Copenhagen
3 Sept 2012 → 15 Aug 2014
Award Date: 15 Aug 2014
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Dive into the research topics where Michael Lückmann is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7
Jorgensen, A. S., Larsen, O., Uetz-von Allmen, E., Lückmann, M., Legler, D. F., Frimurer, T. M., Veldkamp, C. T., Hjortø, G. M. & Rosenkilde, M. M., 13 Sept 2019, In: Frontiers in Immunology. 10, 14 p., 2156.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1
Lückmann, M., Trauelsen, M., Bentsen, M. A., Nissen, T. A. D., Martins, J., Fallah, Z., Nygaard, M. M., Papaleo, E., Lindorff-Larsen, K., Schwartz, T. W. & Frimurer, T. M., 2 Apr 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7123-7128Research output: Contribution to journal › Journal article › Research › peer-review
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Ligand-selective small molecule modulators of the constitutively active vGPCR US28
Amarandi, R.-M., Luckmann, M., Melynis, M., Jakobsen, M. H., Fallah, Z., Spiess, K., Hjorto, G. M., Pui, A., Frimurer, T. M. & Rosenkilde, M. M., 15 Jul 2018, In: European Journal of Medicinal Chemistry. 155, p. 244-254Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1
Rexen Ulven, E., Trauelsen, M., Brvar, M., Lückmann, M., Bielefeldt, L. Ø., Jensen, L. K. I., Schwartz, T. W. & Frimurer, T. M., 1 Dec 2018, In: Scientific Reports. 8, 1, p. 1-18 10010.Research output: Contribution to journal › Journal article › Research › peer-review
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The HETE Is on FFAR1 and Pancreatic Islet Cells
Trauelsen, M., Lückmann, M., Frimurer, T. M. & Schwartz, T. W., 2018, In: Cell Metabolism. 27, 2, p. 273-275 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Translating biased signaling in the ghrelin receptor system into differential in vivo functions
Mende, F., Hundahl, C., Plouffe, B., Skov, L. J., Sivertsen, B., Madsen, A. N., Lückmann, M., Diep, T. A., Offermanns, S., Frimurer, T. M., Bouvier, M. & Holst, B., 23 Oct 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. E10255-E10264 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biased agonism and allosteric modulation of GPR183- a 7TM receptor also known as EBV-induced EBI2
Daugvilaite, V., Madsen, C. M., Lückmann, M., Castello Echeverria, C., Sailer, A. W., Frimurer, T. M., Rosenkilde, M. M. & Benned-Jensen, T., 2017, In: British Journal of Pharmacology. 174, 13, p. 2031–2042Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-based discovery of novel US28 small molecule ligands with different modes of action
Lückmann, M., Amarandi, R.-M., Papargyri, N., Jakobsen, M. H., Christiansen, E., Jensen, L. J., Pui, A., Schwartz, T. W., Rosenkilde, M. M. & Frimurer, T. M., 1 Mar 2017, In: Chemical Biology & Drug Design. 89, 3, p. 289–296Research output: Contribution to journal › Journal article › Research › peer-review