Research output per year
Research output per year
Search results
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2019
Amino acids as stabilizers for spray-dried simvastatin powder for inhalation
Lu, W., Rades, T., Rantanen, J., Chan, H-K. & Yang, M., 15 Dec 2019, In: International Journal of Pharmaceutics. p. 118724Research output: Contribution to journal › Journal article › Research › peer-review
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Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects
Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, A., Rades, T., Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114Research output: Contribution to journal › Review › peer-review
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Co-former selection for co-amorphous drug-amino acid formulations
Kasten, G., Löbmann, K., Grohganz, H. & Rades, T., 25 Feb 2019, In: International Journal of Pharmaceutics. 557, p. 366-373Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of two different PEGylation strategies for the liposomal adjuvant CAF09: Towards induction of CTL responses upon subcutaneous vaccine administration
Tandrup Schmidt, S., Line Olsen, C., Franzyk, H., Wørzner, K., Smith Korsholm, K., Rades, T., Andersen, P., Foged, C. & Christensen, D., Jul 2019, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 140, p. 29-39 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy
Leng, D., Kissi, E. O., Löbmann, K., Thanki, K., Fattal, E., Rades, T., Foged, C. & Yang, M., 1 Apr 2019, In: AAPS PharmSciTech. 20, 3, p. 137Research output: Contribution to journal › Journal article › Research › peer-review
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Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation
Karl, M., Rantanen, J. & Rades, T., 6 Dec 2019, In: Pharmaceutics. 11, 12Research output: Contribution to journal › Journal article › Communication
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Dipeptides as co-formers in co-amorphous systems
Wu, W., Löbmann, K., Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Rades, T. & Grohganz, H., 1 Jan 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 134, p. 68-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Direct Comparison of Standard Transmission Electron Microscopy and Cryogenic-TEM in Imaging Nanocrystals Inside Liposomes
Li, T., Nowell, C. J., Cipolla, D., Rades, T. & Boyd, B. J., 1 Apr 2019, In: Molecular Pharmaceutics. 16, 4, p. 1775-1781Research output: Contribution to journal › Journal article › Research › peer-review
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Direct Measurement of Amorphous Solubility
Stukelj, J., Svanback, S., Agopov, M., Lobmann, K., Strachan, C. J., Rades, T. & Yliruusi, J., 4 Jun 2019, In: Analytical Chemistry. 91, 11, p. 7411-7417Research output: Contribution to journal › Journal article › Research › peer-review
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Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy
Bohr, A., Nascimento, T. L., Harmankaya, N., Weisser, J. J., Wang, Y., Grohganz, H., Rades, T. & Löbmann, K., 11 Jan 2019, In: Molecules. 24, 2, p. 266 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5
Kłodzińska, S. N., Pletzer, D., Rahanjam, N., Rades, T., Hancock, R. E. W. & Nielsen, H. M., 2019, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 20, 102022.Research output: Contribution to journal › Journal article › Research › peer-review
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Imaging of dehydration in particulate matter using Raman line-focus microscopy
Okeyo, P. O., Ilchenko, O., Slipets, R., Larsen, P. E., Boisen, A., Rades, T. & Rantanen, J., 1 Dec 2019, In: Scientific Reports. 9, 11 p., 7525.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of Glass Forming Ability on the Physical Stability of Supersaturated Amorphous Solid Dispersions
Blaabjerg, L. I., Bulduk, B., Lindenberg, E., Löbmann, K., Rades, T. & Grohganz, H., Aug 2019, In: Journal of Pharmaceutical Sciences.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhalable co-amorphous budesonide-arginine dry powders prepared by spray drying
Lu, W., Rades, T., Rantanen, J. & Yang, M., 30 Jun 2019, In: International Journal of Pharmaceutics. 565, p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In situ co-amorphisation in coated tablets – The combination of carvedilol with aspartic acid during immersion in an acidic medium
Petry, I., Löbmann, K., Grohganz, H., Rades, T. & Leopold, C. S., 10 Mar 2019, In: International Journal of Pharmaceutics. 558, p. 357-366 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends
Berthelsen, R., Klitgaard, M., Rades, T. & Müllertz, A., 1 Mar 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.Research output: Contribution to journal › Review › peer-review
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Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement
Rune Jørgensen, J., Leth Jepsen, M., Hagner Nielsen, L., Dufva, M., Mørck Nielsen, H., Rades, T., Boisen, A. & Müllertz, A., Oct 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 143, p. 98-105Research output: Contribution to journal › Journal article › Research › peer-review
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Optimization of Infrared Microscopy to Assess Secondary Structure of Insulin Molecules Within Individual Subvisible Particles in Aqueous Formulations
Schack, M. M., Moller, E. H., Friderichsen, A. V., Carpenter, J. F., Rades, T. & Groenning, M., Mar 2019, In: Journal of Pharmaceutical Sciences. 108, 3, p. 1117-1129Research output: Contribution to journal › Journal article › Research › peer-review
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Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations
Kasten, G., Duarte, Í., Paisana, M., Löbmann, K., Rades, T. & Grohganz, H., 1 Jan 2019, In: Pharmaceutics. 11, 1, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transformations between Co-Amorphous and Co-Crystal Systems and Their Influence on the Formation and Physical Stability of Co-Amorphous Systems
Wu, W., Wang, Y., Löbmann, K., Grohganz, H. & Rades, T., 4 Mar 2019, In: Molecular Pharmaceutics. 16, 3, p. 1294-1304 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Whey proteins as stabilizers in amorphous solid dispersions
Mishra, J., Bohr, A., Rades, T., Grohganz, H. & Löbmann, K., 1 Feb 2019, In: European Journal of Pharmaceutical Sciences. 128, p. 144-151 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2018
A non-destructive method for quality control of the pellet distribution within a MUPS tablet by terahertz pulsed imaging
Novikova, A., Markl, D., Axel Zeitler, J., Rades, T. & Leopold, C. S., 1 Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 549-555Research output: Contribution to journal › Journal article › Research › peer-review
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A Platform for Preparing Homogeneous Proteinaceous Subvisible Particles With Distinct Morphologies
Schack, M. M., Moller, E. H., Carpenter, J. F., Rades, T. & Groenning, M., Jul 2018, In: Journal of Pharmaceutical Sciences. 107, 7, p. 1842-1851Research output: Contribution to journal › Journal article › Research › peer-review
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Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine
Ueda, H., Wu, W., Lobmann, K., Grohganz, H., Mullertz, A. & Rades, T., 7 May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044Research output: Contribution to journal › Journal article › Research › peer-review
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Are phytosomes a superior nanodelivery system for the antioxidant rutin?
Vu, H. T. H., Hook, S. M., Siqueira, S. D., Müllertz, A., Rades, T. & McDowell, A., 2018, In: International Journal of Pharmaceutics. 548, 1, p. 82-91 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Aspartame as a co-former in co-amorphous systems
Wu, W., Lobmann, K., Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Grohganz, H. & Rades, T., 5 Oct 2018, In: International Journal of Pharmaceutics. 549, 1-2, p. 380-387Research output: Contribution to journal › Journal article › Research › peer-review
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Characterisation of pore structures of pharmaceutical tablets: A review
Markl, D., Strobel, A., Schlossnikl, R., Bøtker, J., Bawuah, P., Ridgway, C., Rantanen, J., Rades, T., Gane, P., Peiponen, K-E. & Zeitler, J. A., 1 Mar 2018, In: International Journal of Pharmaceutics. 538, 1, p. 188-214 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of the hydrodynamics in a miniaturized dissolution apparatus
Johansson, K. E., Plum, J., Mosleh, M., Madsen, C. M., Rades, T. & Müllertz, A., Apr 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Combining diagnostic methods for antimicrobial susceptibility testing – A comparative approach
Klodzinska, S. N., Priemel, P. A., Rades, T. & Nielsen, H. M., Jan 2018, In: Journal of Microbiological Methods. 144, p. 177-185Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of two DSC-based methods to predict drug-polymer solubility
Rask, M. B., Knopp, M. M., Olesen, N. E., Holm, R. & Rades, T., 5 Apr 2018, In: International Journal of Pharmaceutics. 540, 1-2, p. 98-105Research output: Contribution to journal › Journal article › Research › peer-review
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Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems
Kheawfu, K., Pikulkaew, S., Rades, T., Müllertz, A. & Okonogi, S., 2018, In: Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Drug nanocrystallisation within liposomes
Li, T., Cipolla, D., Rades, T. & Boyd, B. J., 2018, In: Journal of Controlled Release. 288, p. 96-110 15 p.Research output: Contribution to journal › Review › peer-review
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Effect of amorphous phase separation and crystallization on the in vitro and in vivo performance of an amorphous solid dispersion
Knopp, M. M., Wendelboe, J., Holm, R. & Rades, T., Sept 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 130, p. 290-295Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments
Madsen, C. M., Feng, K-I., Leithead, A., Canfield, N., Jørgensen, S. A., Müllertz, A. & Rades, T., 1 Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor® RH40 using experimental design
Tran, T., Rades, T. & Müllertz, A., Nov 2018, In: Asian Journal of Pharmaceutical Sciences. 13, p. 536-545Research output: Contribution to journal › Journal article › Research › peer-review
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Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs
Kissi, E. O., Grohganz, H., Löbmann, K., Ruggiero, M. T., Zeitler, J. A. & Rades, T., 15 Mar 2018, In: Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical. 122, 10, p. 2803-2808 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein
Rodrigues, L., Raftopoulos, K. N., Tandrup Schmidt, S., Schneider, F., Dietz, H., Rades, T., Franzyk, H., Pedersen, A. E., Papadakis, C. M., Christensen, D., Winter, G., Foged, C. & Hubert, M., 10 Sept 2018, In: Journal of controlled release : official journal of the Controlled Release Society. 285, p. 12-22 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)
Schmidt, S. T., Pedersen, G. K., Neustrup, M. A., Korsholm, K. S., Rades, T., Andersen, P., Foged, C. & Christensen, D., 30 Apr 2018, In: Frontiers in Immunology. 9, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of preparation technique on co-amorphization of carvedilol with acidic amino acids
Mishra, J., Lobmann, K., Grohganz, H. & Rades, T., 1 Dec 2018, In: International Journal of Pharmaceutics. 552, 1-2, p. 407-413Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of PVP molecular weight on the microwave assisted in situ amorphization of indomethacin
Doreth, M., Löbmann, K., Priemel, P., Grohganz, H., Taylor, R., Holm, R., Lopez de Diego, H. & Rades, T., Jan 2018, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 122, p. 62-69Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
Mishra, J., Rades, T., Löbmann, K. & Grohganz, H., Jun 2018, In: Pharmaceutics. 10, 2, p. 1-13Research output: Contribution to journal › Journal article › Research › peer-review
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In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium – A proof of concept study
Petry, I., Löbmann, K., Grohganz, H., Rades, T. & Leopold, C. S., 1 Dec 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 133, p. 151-160 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-arginine
Kasten, G., Lobo, L., Dengale, S., Grohganz, H., Rades, T. & Löbmann, K., 1 Nov 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 132, p. 192-199 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Is there a correlation between the glass forming ability of a drug and its supersaturation propensity?
Blaabjerg, L. I., Lindenberg, E., Lobmann, K., Grohganz, H. & Rades, T., 1 Mar 2018, In: International Journal of Pharmaceutics. 538, 1-2, p. 243-249Research output: Contribution to journal › Journal article › Research › peer-review
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On the role of salt formation and structural similarity of co-formers in co-amorphous drug delivery systems
Wu, W., Löbmann, K., Rades, T. & Grohganz, H., 15 Jan 2018, In: International Journal of Pharmaceutics. 535, 1-2, p. 86-94Research output: Contribution to journal › Journal article › Research › peer-review
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Organic acids as co-formers for co-amorphous systems - Influence of variation in molar ratio on the physicochemical properties of the co-amorphous systems
Wu, W., Ueda, H., Lobmann, K., Rades, T. & Grohganz, H., Oct 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 131, p. 25-32Research output: Contribution to journal › Journal article › Research › peer-review
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Quantification of microwave-induced amorphization of celecoxib in PVP tablets using transmission Raman spectroscopy
Edinger, M., Knopp, M. M., Kerdoncuff, H., Rantanen, J., Rades, T. & Lobmann, K., 30 May 2018, In: European Journal of Pharmaceutical Sciences. 117, p. 62-67Research output: Contribution to journal › Journal article › Research › peer-review
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Spray dried cubosomes with ovalbumin and Quil-A as a nanoparticulate dry powder vaccine formulation
von Halling Laier, C., Gibson, B., van de Weert, M., Boyd, B. J., Rades, T., Boisen, A., Hook, S. & Nielsen, L. H., 25 Oct 2018, In: International Journal of Pharmaceutics. 550, 1-2, p. 35-44 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens
Jorgensen, S. D. S., Al Sawaf, M., Graeser, K., Mu, H., Muellertz, A. & Rades, T., Mar 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 124, p. 116-124Research output: Contribution to journal › Journal article › Research › peer-review
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The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers
Blaabjerg, L. I., Grohganz, H., Lindenberg, E., Löbmann, K., Mullertz, A. & Rades, T., Dec 2018, In: Pharmaceutics. 10, 4, 14 p., 164.Research output: Contribution to journal › Journal article › Research › peer-review