Research output per year
Research output per year
Personal profile
Primary fields of research
Design and development of in vitro models to evaluate oral drug performance. In vivo bioavailability studies and predictive in vitro models, simulating the gastro-intestinal tract to understand mechanisms of drug solubilization and absorption. Special focus on drug delivery to the pediatric population.
Teaching
Pharmaceutisk Fysisk-Kemi
Farmaci I
Farmaci II
Advanced Drug Delivery
Education/Academic qualification
In vitro models for the prediction of gastrointestinal drug absorption of poorly water soluble drugs
May 2010 → Dec 2014
Award Date: 23 Dec 2014
Characterization of the basolateral peptide transporter in Caco-2 cells
Sept 2003 → Oct 2009
Award Date: 6 Oct 2009
Keywords
- Former Faculty of Pharmaceutical Sciences
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Dive into the research topics where Ragna Berthelsen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends
Berthelsen, R., Klitgaard, M., Rades, T. & Müllertz, A., 1 Mar 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.Research output: Contribution to journal › Review › peer-review
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In Vitro Model Simulating Gastro-Intestinal Digestion in the Pediatric Population (Neonates and Young Infants)
Kamstrup, D., Berthelsen, R., Sassene, P. J., Selen, A. & Müllertz, A., 1 Feb 2017, In: A A P S PharmSciTech. 18, 2, p. 317-329 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Studying furosemide solubilization using an in vitro model simulating gastrointestinal digestion and drug solubilization in neonates and young infants
Klitgaard, M., Sassene, P. J., Selen, A., Müllertz, A. & Berthelsen, R., 15 Nov 2017, In: European Journal of Pharmaceutical Sciences. 109, p. 191-199 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of a μDissolution-Permeation model with in situ drug concentration monitoring
Berthelsen, R., Byrialsen, J. P., Holm, R., Jacobsen, J., Abrahamsson, B., Saabye, L., Madelung, P. & Müllertz, A., 1 Oct 2016, In: Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dissolution Model Development: Formulation Effects and Filter Complications
Berthelsen, R., Holm, R., Jacobsen, J., Kristensen, J., Abrahamsson, B. & Mullertz, A., Feb 2016, In: Dissolution Technologies. 23, 1, p. 6-12 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats.
Berthelsen, R., Holm, R., Jacobsen, J., Kristensen, J., Abrahamsson, B. & Müllertz, A., 13 Feb 2015, In: Molecular Pharmaceutics. 12, 4, p. 1062-1071 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
27 Citations (Scopus) -
Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example
Berthelsen, R., Sjögren, E., Jacobsen, J., Kristensen, J., Holm, R., Abrahamsson, B. & Müllertz, A., 1 Oct 2014, In: International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Basolateral glycylsarcosine (Gly-Sar) transport in Caco-2 cell monolayers is pH dependent
Berthelsen, R., Nielsen, C. U. & Brodin, B., Jul 2013, In: Journal of Pharmacy and Pharmacology. 65, 7, p. 970-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review