Paul Robert Hansen

2019

A Biophysical Study of the Interactions between the Antimicrobial Peptide Indolicidin and Lipid Model Systems

Nielsen, J. E., Lind, T. K., Lone, A., Gerelli, Y., Hansen, P. R., Jenssen, H., Cárdenas, M. & Lund, R., 7 Apr 2019, (Accepted/In press) In: B B A - Biomembranes.

Research output: Contribution to journal › Journal article › Research › peer-review

Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients

Molchanova, N., Wang, H., Hansen, P. R., Høiby, N., Nielsen, H. M. & Franzyk, H., Feb 2019, In: Frontiers in Microbiology. 10, 9 p., 275.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

53 Downloads (Pure)

Characterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections

Greco, I., Emborg, A., Jana, B., Molchanova, N., Oddo, A., Damborg, P. P., Guardabassi, L. & Hansen, P. R., 1 Dec 2019, In: Scientific Reports. 9, 12 p., 3679.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

41 Downloads (Pure)

Fine mapping of glutamate decarboxylase 65 epitopes reveals dependency of hydrophobic amino acids for specific interactions

Valdarnini, N., Holm, B., Hansen, P. R., Rovero, P., Houen, G. & Trier, N. H., 10 Jun 2019, (Accepted/In press) In: International Journal of Molecular Sciences (Online).

Research output: Contribution to journal › Journal article › Research › peer-review

Fluorescent analogues of Human α-Calcitonin Gene-Related Peptide with vasodilator potency.

Zhu, J., Pedersen, M. D., Ahmed, L. S., Abdolalizadeh, B., Grell, A. S. J., Berg, J. O., Thulstrup, P. W., Franzyk, H., Edvinsson, L., Sams, A., Sheykhzade, M. & Hansen, P. R., 20 Dec 2019, (Submitted) In: International Journal of Molecular Sciences (Online).

Research output: Contribution to journal › Journal article › Research › peer-review

Peptide/Peptoid Hybrid Oligomers: The Influence of Hydrophobicity and Relative Side-Chain Length on Antibacterial Activity and Cell Selectivity

Frederiksen, N., Hansen, P. R., Björkling, F. & Franzyk, H., 4 Dec 2019, In: Molecules (Print Archive Edition). 24, 18 p., 4429.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Peptides, antibodies, peptide antibodies and more

Trier, N., Hansen, P. R. & Houen, G., 2 Dec 2019, In: International Journal of Molecular Sciences (Online).

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Specificity of anti-citrullinated protein antibodies in rheumatoid arthritis

Trier, N., Holm, B. E., Hansen, P. R., Slot, O., Locht, H. & Houen, G., Jun 2019, In: Antibodies. 8, 2, 10 p., 37.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Downloads (Pure)

Structure-activity study, characterization and mechanism of action of an antimicrobial peptoid D2 and its D- and L-peptide analogues

Greco, I., Hansen, J. E., Jana, B., Molchanova, N., Oddo, A., Thulstrup, P. W., Damborg, P. P., Guardabassi, L. & Hansen, P. R., 21 Mar 2019, In: Molecules. 24, 6, 16 p., 1121.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

37 Downloads (Pure)

Structure-activity study of an all-D-antimicrobial octapeptide

Lone, A. B. N., Thomsen, T. T., Nielsen, J. E., Thulstrup, P. W., Klitgaard, R. N., Løbner-Olesen, A., Lund, R., Jenssen, H. & Hansen, P. R., 11 Dec 2019, (Accepted/In press) In: Molecules.

Research output: Contribution to journal › Journal article › Research › peer-review

2018

Biopolymer nanogels improve antibacterial activity and safety profile of a novel lysine-based α-peptide/β-peptoid peptidomimetic

Kłodzińska, S. N., Molchanova, N., Franzyk, H., Hansen, P. R., Damborg, P. & Nielsen, H. M., Jul 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 128, p. 1-9 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Fluorinated antimicrobial lysine-based peptidomimetics with activity against methicillin-resistant Staphylococcus pseudintermedius

Molchanova, N., Hansen, P. R., Damborg, P. & Franzyk, H., Jul 2018, In: Journal of Peptide Science. 24, 7, 8 p., e3098.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Fmoc Solid-Phase Synthesis of Human a-Calcitonin Gene- Related Peptide and Two Carboxyfluorescein-labeled Analogs

Ahmed, L. S., Abdolalizadeh, B., Sheykhzade, M. & Hansen, P. R., 11 Feb 2018.

Research output: Contribution to conference › Poster › Research › peer-review

In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma

Greco, I., Hummel, B. D., Vasir, J., Watts, J. L., Koch, J., Hansen, J. E., Nielsen, H. M., Damborg, P. P. & Hansen, P. R., 10 Mar 2018, In: Molecules. 23, 3, 15 p., 630.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

96 Downloads (Pure)

Linear peptidomimetics as potent antagonists of Staphylococcus aureus agr quorum sensing

Karathanasi, G., Bojer, M. S., Baldry, M., Johannessen, B. A., Wolff, S., Greco, I., Kilstrup, M., Hansen, P. R. & Ingmer, H., 1 Dec 2018, In: Scientific Reports. 8, 1, 11 p., 3562.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

74 Downloads (Pure)

Review on abyssomicins: Inhibitors of the chorismate pathway and folate biosynthesis

Sadaka, C., Ellsworth, E., Hansen, P. R., Ewin, R., Damborg, P. & Watts, J. L., 2018, In: Molecules. 23, 6, 25 p., 1371.

Research output: Contribution to journal › Review › peer-review

14 Citations (Scopus)

50 Downloads (Pure)

The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells

Prabhala, B. K., Aduri, N. G., Sharma, N., Shaheen, A., Sharma, A., Iqbal, M., Hansen, P. R., Brasen, C., Gajhede, M., Rahman, M. & Mirza, O., 19 Jan 2018, In: The Journal of Biological Chemistry. 293, p. 1007-1017

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

2017

Advances in development of antimicrobial peptidomimetics as potential drugs

Molchanova, N., Hansen, P. R. & Franzyk, H., Sept 2017, In: Molecules. 22, 9, 60 p., 1430.

Research output: Contribution to journal › Review › peer-review

104 Citations (Scopus)

124 Downloads (Pure)

Broadening CD4(+) and CD8(+) T Cell Responses against Hepatitis C Virus by Vaccination with NS3 Overlapping Peptide Panels in Cross-Priming Liposomes

Filskov, J., Mikkelsen, M., Hansen, P. R., Christensen, J. P., Thomsen, A. R., Andersen, P., Bukh, J. & Agger, E-M., 1 Jul 2017, In: Journal of Virology. 91, 14, 18 p., e00130-17.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Chemical Synthesis of Antimicrobial Peptides.

Münzker, L., Oddo, A. & Hansen, P. R., 2017, Chemical Synthesis of Antimicrobial Peptides: Münzker L, Oddo A, Hansen PR. Methods Mol Biol. 2017; . Hansen, P. R. (ed.). Springer, Vol. 1548. p. 35-49.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

7 Citations (Scopus)

Hemolytic Activity of Antimicrobial Peptides

Oddo, A. & Hansen, P. R., 2017, Methods in molecular biology. Hansen, P. R. (ed.). Springer, Vol. 1548. p. 427-435

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

37 Citations (Scopus)

Lysine-Based α-peptide/β-peptoid peptidomimetics: Influence of hydrophobicity, fluorination and distribution of cationic charge on antimicrobial activity and cytotoxicity

Molchanova, N., Hansen, P. R., Damborg, P. P., Nielsen, H. M. & Franzyk, H., 20 Feb 2017, In: ChemMedChem. 12, p. 312-318 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

27 Citations (Scopus)

Methods in Molecular Biology: Antimicrobial Peptides Methods and Protocols

Hansen, P. R. (ed.), 1 Jan 2017, Springer. 439 p.

Research output: Book/Report › Book › Research › peer-review

Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR

Prabhala, B. K., Aduri, N. G., Iqbal, M., Rahman, M., Gajhede, M., Hansen, P. R. & Mirza, O., Jun 2017, In: Research in Microbiology. 168, 5, p. 443-449

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Structure-activity relationship studies of lysine-based α-peptide/β-peptoid antimicrobial peptidomimetics

Molchanova, N., Hansen, P. R., Damborg, P. P. & Franzyk, H., 2017. 1 p.

Research output: Contribution to conference › Poster › Research › peer-review

214 Downloads (Pure)

2016

An amphipathic undecapeptide with all D-amino acids shows promising activity against colistin-resistant strains of Acinetobacter baumannii and a dual mode of action

Oddo, A., Thomsen, T. T., Kjelstrup, S., Gorey, C., Franzyk, H., Frimodt-Møller, N., Løbner-Olesen, A. & Hansen, P. R., 1 Jan 2016, In: Antimicrobial Agents and Chemotherapy. 60, 1, p. 592-599 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

Modulation of backbone flexibility for effective dissociation of antibacterial and hemolytic activity in cyclic peptides

Oddo, A., Thomsen, T. T., Britt, H. M., Løbner-Olesen, A., Thulstrup, P. W., Sanderson, J. M. & Hansen, P. R., 11 Aug 2016, In: ACS Medicinal Chemistry Letters. 7, 8, p. 741-745 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Roles of hydrophobicity, fluorination and distribution of cationic residues in α-peptide/β-peptoids for antibacterial and hemolytic properties

Molchanova, N., Hansen, P. R., Damborg, P. P. & Franzyk, H., 2016. 1 p.

Research output: Contribution to conference › Poster › Research

2015

[64Cu]-Labelled Trastuzumab: Optimisation of Labelling by DOTA and NODAGA Conjugation and Initial Evaluation in Mice

Schjøth-Eskesen, C., Nielsen, C. H., Heissel, S., Højrup, P., Hansen, P. R., Gillings, N. & Kjær, A., 30 May 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, 6, p. 227-33 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Amphibian antimicrobial peptide fallaxin analogue FL9 affects virulence gene expression and DNA replication in Staphylococcus aureus

Gottschalk, S., Gottlieb, C. T., Vestergaard, M., Hansen, P. R., Gram, L., Ingmer, H. & Thomsen, L. E., 1 Dec 2015, In: Journal of Medical Microbiology. 64, 12, p. 1504-1513 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

An ANOVA-based model to identify the optimal antimicrobial peptide in a combination matrix

Munk, J. K., Ritz, C., Fliedner, F. P., Frimodt-Moller, N. & Hansen, P. R., 2015.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Antibodies with specificity for native and denatured forms of ovalbumin differ in reactivity between enzyme-linked immunosorbent assays.

Holm, B. E., Bergmann, A. C., Hansen, P. R., Koch, C., Houen, G. & Trier, N. H., 1 Feb 2015, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 123, 2, p. 136–145 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Antimicrobial activities of synthetic anoplin analogues against methicillin-resistant Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, vancomycin-resistant Enterococcus faecium and Candida albicans

Munk, J. K., Uggerhøj, L. E., Poulsen, T. J., Frimodt-Moller, N., Nyberg, N., Wimmer, R. & Hansen, P. R., 2015.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Characterization of synthetic peptides by mass spectrometry

Prabhala, B. K., Mirza, O. A., Højrup, P. & Hansen, P. R., 2015, Methods in Molecular Biology: Peptide Antibiodies. Springer, p. 77-82

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

1 Citation (Scopus)

Contribution of peptide backbone to Anti-citrulline-dependent antibody reactivity

Trier, N. H., Dam, C., Olsen, D., Hansen, P. R. & Houen, G., 1 Dec 2015, In: P L o S One. p. 1-12 12 p., 0144707.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Efficient, regioselective ring-opening of activated aziridine-2-carboxylates with [¹⁸F]fluoride

Schjøth-Eskesen, C., Hansen, P. R., Kjær, A. & Gillings, N., Feb 2015, In: ChemistryOpen. 4, 1, p. 65–71 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Fmoc Solid-Phase Peptide Synthesis

Hansen, P. R. & Oddo, A., 2015, Methods in Molecular Biology: Peptide Antibodies. Vol. 1348. p. 33-50 18 p.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

33 Citations (Scopus)

Identifying immunogenic CD4+ T-cell epitopes of Myeloid cell leukemia 1 using overlapping 20-mer peptides spanning the whole protein.

Woodworth, J. S., Agger, E. M. & Hansen, P. R., 2015, Proceedings of the 24th American Peptide Symposium Ved Srivastava, Andrei Yudin, and Michal Lebl (Editors) American Peptide Society. p. 262-63 2 p.

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

Novel classes of antimicrobials in veterinary medicine: Characterizing peptoids as topical agents for dog skin infections

Greco, I., Damborg, P. P., Guardabassi, L., Vasir, J., Watts, J., Hummel, B. D. & Hansen, P. R., 2015.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Novel compounds with selective antimicrobial activity against Staphylococcus pseudintermedius and Pseudomonas aeruginosa causing pyoderma in dogs

Greco, I., Emborg, A., Oddo, A., Damborg, P. P., Guardabassi, L. & Hansen, P. R., 2015.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Peptide-Carrier Conjugation: Methods in Molecular Biology

Hansen, P. R., 2015, Methods in Molecular Biology: Peptide Antibodies. Vol. 1348. p. 51-57 7 p.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Peptide Macrocycles Featuring a Backbone Secondary Amine: A Convenient Strategy for the Synthesis of Lipidated Cyclic and Bicyclic Peptides on Solid Support

Oddo, A., Münzker, L. & Hansen, P. R., 15 May 2015, In: Organic Letters. 17, 10, p. 2502-2505 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Rational Design of alpha-helical antimicrobial peptides: DOs and DON’Ts

Uggerhøj, L. E., Poulsen, T. J., Munk, J. K., Fredborg, M., Sondergaard, T. E., Frimodt-Møller, N., Hansen, P. R. & Wimmer, R., 21 Dec 2015, In: ChemBioChem. 16, 2, p. 242–253 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

45 Citations (Scopus)

The effect of glycine replacement with flexible ω-amino acids on the antimicrobial and haemolytic activity of an amphipathic cyclic heptapeptide

Oddo, A., Nyberg, N., Frimodt-Møller, N., Thulstrup, P. W. & Hansen, P. R., 18 Sept 2015, In: European Journal of Medicinal Chemistry. 102, p. 574-581 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

2014

AMP mimics with bactericidal activity against Staphylococci and Pseudomonas as novel drugs for topical use in veterinary medicine

Greco, I., Damborg, P. P., Guardabassi, L., Nielsen, H. M. & Hansen, P. R., 4 Jun 2014.

Research output: Contribution to conference › Poster › Research › peer-review

Identification and fine mapping of a linear B cell epitope of human vimentin

Dam, C. E., Houen, G., Hansen, P. R. & Trier, N., 1 Sept 2014, In: Scandinavian Journal of Clinical & Laboratory Investigation. 74, 6, p. 506-514 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Identification of a linear epitope recognized by a monoclonal antibody directed to the heterogeneous nucleoriboprotein A2

Tronstrøm, J., Dragborg, A. H., Hansen, P. R., Houen, G. & Trier, N. H., Jan 2014, In: Protein and Peptide Letters. 21, 1, p. 25-31 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Paul Robert Hansen

Research output

Search results