Paul Robert Hansen

2019

A Biophysical Study of the Interactions between the Antimicrobial Peptide Indolicidin and Lipid Model Systems

Nielsen, J. E., Lind, T. K., Lone, A., Gerelli, Y., Hansen, P. R., Jenssen, H., Cárdenas, M. & Lund, R., 7 apr. 2019, (Accepteret/In press) I: B B A - Biomembranes.

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Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients

Molchanova, N., Wang, H., Hansen, P. R., Høiby, N., Nielsen, H. M. & Franzyk, H., feb. 2019, I: Frontiers in Microbiology. 10, 9 s., 275.

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6 Citationer (Scopus)

53 Downloads (Pure)

Characterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections

Greco, I., Emborg, A., Jana, B., Molchanova, N., Oddo, A., Damborg, P. P., Guardabassi, L. & Hansen, P. R., 1 dec. 2019, I: Scientific Reports. 9, 12 s., 3679.

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10 Citationer (Scopus)

41 Downloads (Pure)

Fine mapping of glutamate decarboxylase 65 epitopes reveals dependency of hydrophobic amino acids for specific interactions

Valdarnini, N., Holm, B., Hansen, P. R., Rovero, P., Houen, G. & Trier, N. H., 10 jun. 2019, (Accepteret/In press) I: International Journal of Molecular Sciences (Online).

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Fluorescent analogues of Human α-Calcitonin Gene-Related Peptide with vasodilator potency.

Zhu, J., Pedersen, M. D., Ahmed, L. S., Abdolalizadeh, B., Grell, A. S. J., Berg, J. O., Thulstrup, P. W., Franzyk, H., Edvinsson, L., Sams, A., Sheykhzade, M. & Hansen, P. R., 20 dec. 2019, (Afsendt) I: International Journal of Molecular Sciences (Online).

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Peptide/Peptoid Hybrid Oligomers: The Influence of Hydrophobicity and Relative Side-Chain Length on Antibacterial Activity and Cell Selectivity

Frederiksen, N., Hansen, P. R., Björkling, F. & Franzyk, H., 4 dec. 2019, I: Molecules (Print Archive Edition). 24, 18 s., 4429.

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6 Citationer (Scopus)

Peptides, antibodies, peptide antibodies and more

Trier, N., Hansen, P. R. & Houen, G., 2 dec. 2019, I: International Journal of Molecular Sciences (Online).

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11 Citationer (Scopus)

Specificity of anti-citrullinated protein antibodies in rheumatoid arthritis

Trier, N., Holm, B. E., Hansen, P. R., Slot, O., Locht, H. & Houen, G., jun. 2019, I: Antibodies. 8, 2, 10 s., 37.

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6 Downloads (Pure)

Structure-activity study, characterization and mechanism of action of an antimicrobial peptoid D2 and its D- and L-peptide analogues

Greco, I., Hansen, J. E., Jana, B., Molchanova, N., Oddo, A., Thulstrup, P. W., Damborg, P. P., Guardabassi, L. & Hansen, P. R., 21 mar. 2019, I: Molecules. 24, 6, 16 s., 1121.

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7 Citationer (Scopus)

37 Downloads (Pure)

Structure-activity study of an all-D-antimicrobial octapeptide

Lone, A. B. N., Thomsen, T. T., Nielsen, J. E., Thulstrup, P. W., Klitgaard, R. N., Løbner-Olesen, A., Lund, R., Jenssen, H. & Hansen, P. R., 11 dec. 2019, (Accepteret/In press) I: Molecules.

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2018

Biopolymer nanogels improve antibacterial activity and safety profile of a novel lysine-based α-peptide/β-peptoid peptidomimetic

Kłodzińska, S. N., Molchanova, N., Franzyk, H., Hansen, P. R., Damborg, P. & Nielsen, H. M., jul. 2018, I: European Journal of Pharmaceutics and Biopharmaceutics. 128, s. 1-9 9 s.

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17 Citationer (Scopus)

Fluorinated antimicrobial lysine-based peptidomimetics with activity against methicillin-resistant Staphylococcus pseudintermedius

Molchanova, N., Hansen, P. R., Damborg, P. & Franzyk, H., jul. 2018, I: Journal of Peptide Science. 24, 7, 8 s., e3098.

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6 Citationer (Scopus)

Fmoc Solid-Phase Synthesis of Human a-Calcitonin Gene- Related Peptide and Two Carboxyfluorescein-labeled Analogs

Ahmed, L. S., Abdolalizadeh, B., Sheykhzade, M. & Hansen, P. R., 11 feb. 2018.

Publikation: Konferencebidrag › Poster › Forskning › peer review

In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma

Greco, I., Hummel, B. D., Vasir, J., Watts, J. L., Koch, J., Hansen, J. E., Nielsen, H. M., Damborg, P. P. & Hansen, P. R., 10 mar. 2018, I: Molecules. 23, 3, 15 s., 630.

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5 Citationer (Scopus)

96 Downloads (Pure)

Linear peptidomimetics as potent antagonists of Staphylococcus aureus agr quorum sensing

Karathanasi, G., Bojer, M. S., Baldry, M., Johannessen, B. A., Wolff, S., Greco, I., Kilstrup, M., Hansen, P. R. & Ingmer, H., 1 dec. 2018, I: Scientific Reports. 8, 1, 11 s., 3562.

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8 Citationer (Scopus)

74 Downloads (Pure)

Review on abyssomicins: Inhibitors of the chorismate pathway and folate biosynthesis

Sadaka, C., Ellsworth, E., Hansen, P. R., Ewin, R., Damborg, P. & Watts, J. L., 2018, I: Molecules. 23, 6, 25 s., 1371.

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14 Citationer (Scopus)

50 Downloads (Pure)

The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells

Prabhala, B. K., Aduri, N. G., Sharma, N., Shaheen, A., Sharma, A., Iqbal, M., Hansen, P. R., Brasen, C., Gajhede, M., Rahman, M. & Mirza, O., 19 jan. 2018, I: The Journal of Biological Chemistry. 293, s. 1007-1017

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7 Citationer (Scopus)

2017

Advances in development of antimicrobial peptidomimetics as potential drugs

Molchanova, N., Hansen, P. R. & Franzyk, H., sep. 2017, I: Molecules. 22, 9, 60 s., 1430.

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104 Citationer (Scopus)

124 Downloads (Pure)

Broadening CD4(+) and CD8(+) T Cell Responses against Hepatitis C Virus by Vaccination with NS3 Overlapping Peptide Panels in Cross-Priming Liposomes

Filskov, J., Mikkelsen, M., Hansen, P. R., Christensen, J. P., Thomsen, A. R., Andersen, P., Bukh, J. & Agger, E-M., 1 jul. 2017, I: Journal of Virology. 91, 14, 18 s., e00130-17.

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7 Citationer (Scopus)

Chemical Synthesis of Antimicrobial Peptides.

Münzker, L., Oddo, A. & Hansen, P. R., 2017, Chemical Synthesis of Antimicrobial Peptides: Münzker L, Oddo A, Hansen PR. Methods Mol Biol. 2017; . Hansen, P. R. (red.). Springer, Bind 1548. s. 35-49.

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7 Citationer (Scopus)

Hemolytic Activity of Antimicrobial Peptides

Oddo, A. & Hansen, P. R., 2017, Methods in molecular biology. Hansen, P. R. (red.). Springer, Bind 1548. s. 427-435

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37 Citationer (Scopus)

Lysine-Based α-peptide/β-peptoid peptidomimetics: Influence of hydrophobicity, fluorination and distribution of cationic charge on antimicrobial activity and cytotoxicity

Molchanova, N., Hansen, P. R., Damborg, P. P., Nielsen, H. M. & Franzyk, H., 20 feb. 2017, I: ChemMedChem. 12, s. 312-318 7 s.

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27 Citationer (Scopus)

Methods in Molecular Biology: Antimicrobial Peptides Methods and Protocols

Hansen, P. R. (red.), 1 jan. 2017, Springer. 439 s.

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Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR

Prabhala, B. K., Aduri, N. G., Iqbal, M., Rahman, M., Gajhede, M., Hansen, P. R. & Mirza, O., jun. 2017, I: Research in Microbiology. 168, 5, s. 443-449

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6 Citationer (Scopus)

Structure-activity relationship studies of lysine-based α-peptide/β-peptoid antimicrobial peptidomimetics

Molchanova, N., Hansen, P. R., Damborg, P. P. & Franzyk, H., 2017. 1 s.

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214 Downloads (Pure)

2016

An amphipathic undecapeptide with all D-amino acids shows promising activity against colistin-resistant strains of Acinetobacter baumannii and a dual mode of action

Oddo, A., Thomsen, T. T., Kjelstrup, S., Gorey, C., Franzyk, H., Frimodt-Møller, N., Løbner-Olesen, A. & Hansen, P. R., 1 jan. 2016, I: Antimicrobial Agents and Chemotherapy. 60, 1, s. 592-599 8 s.

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20 Citationer (Scopus)

Modulation of backbone flexibility for effective dissociation of antibacterial and hemolytic activity in cyclic peptides

Oddo, A., Thomsen, T. T., Britt, H. M., Løbner-Olesen, A., Thulstrup, P. W., Sanderson, J. M. & Hansen, P. R., 11 aug. 2016, I: ACS Medicinal Chemistry Letters. 7, 8, s. 741-745 5 s.

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4 Citationer (Scopus)

Roles of hydrophobicity, fluorination and distribution of cationic residues in α-peptide/β-peptoids for antibacterial and hemolytic properties

Molchanova, N., Hansen, P. R., Damborg, P. P. & Franzyk, H., 2016. 1 s.

Publikation: Konferencebidrag › Poster › Forskning

2015

[64Cu]-Labelled Trastuzumab: Optimisation of Labelling by DOTA and NODAGA Conjugation and Initial Evaluation in Mice

Schjøth-Eskesen, C., Nielsen, C. H., Heissel, S., Højrup, P., Hansen, P. R., Gillings, N. & Kjær, A., 30 maj 2015, I: Journal of Labelled Compounds and Radiopharmaceuticals. 58, 6, s. 227-33 7 s.

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12 Citationer (Scopus)

Amphibian antimicrobial peptide fallaxin analogue FL9 affects virulence gene expression and DNA replication in Staphylococcus aureus

Gottschalk, S., Gottlieb, C. T., Vestergaard, M., Hansen, P. R., Gram, L., Ingmer, H. & Thomsen, L. E., 1 dec. 2015, I: Journal of Medical Microbiology. 64, 12, s. 1504-1513 10 s.

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12 Citationer (Scopus)

An ANOVA-based model to identify the optimal antimicrobial peptide in a combination matrix

Munk, J. K., Ritz, C., Fliedner, F. P., Frimodt-Moller, N. & Hansen, P. R., 2015.

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Antibodies with specificity for native and denatured forms of ovalbumin differ in reactivity between enzyme-linked immunosorbent assays.

Holm, B. E., Bergmann, A. C., Hansen, P. R., Koch, C., Houen, G. & Trier, N. H., 1 feb. 2015, I: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 123, 2, s. 136–145 10 s.

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8 Citationer (Scopus)

Antimicrobial activities of synthetic anoplin analogues against methicillin-resistant Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, vancomycin-resistant Enterococcus faecium and Candida albicans

Munk, J. K., Uggerhøj, L. E., Poulsen, T. J., Frimodt-Moller, N., Nyberg, N., Wimmer, R. & Hansen, P. R., 2015.

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Characterization of synthetic peptides by mass spectrometry

Prabhala, B. K., Mirza, O. A., Højrup, P. & Hansen, P. R., 2015, Methods in Molecular Biology: Peptide Antibiodies. Springer, s. 77-82

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1 Citationer (Scopus)

Contribution of peptide backbone to Anti-citrulline-dependent antibody reactivity

Trier, N. H., Dam, C., Olsen, D., Hansen, P. R. & Houen, G., 1 dec. 2015, I: P L o S One. s. 1-12 12 s., 0144707.

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13 Citationer (Scopus)

Efficient, regioselective ring-opening of activated aziridine-2-carboxylates with [¹⁸F]fluoride

Schjøth-Eskesen, C., Hansen, P. R., Kjær, A. & Gillings, N., feb. 2015, I: ChemistryOpen. 4, 1, s. 65–71 7 s.

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6 Citationer (Scopus)

Fmoc Solid-Phase Peptide Synthesis

Hansen, P. R. & Oddo, A., 2015, Methods in Molecular Biology: Peptide Antibodies. Bind 1348. s. 33-50 18 s.

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33 Citationer (Scopus)

Identifying immunogenic CD4+ T-cell epitopes of Myeloid cell leukemia 1 using overlapping 20-mer peptides spanning the whole protein.

Woodworth, J. S., Agger, E. M. & Hansen, P. R., 2015, Proceedings of the 24th American Peptide Symposium Ved Srivastava, Andrei Yudin, and Michal Lebl (Editors) American Peptide Society. s. 262-63 2 s.

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Novel classes of antimicrobials in veterinary medicine: Characterizing peptoids as topical agents for dog skin infections

Greco, I., Damborg, P. P., Guardabassi, L., Vasir, J., Watts, J., Hummel, B. D. & Hansen, P. R., 2015.

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Novel compounds with selective antimicrobial activity against Staphylococcus pseudintermedius and Pseudomonas aeruginosa causing pyoderma in dogs

Greco, I., Emborg, A., Oddo, A., Damborg, P. P., Guardabassi, L. & Hansen, P. R., 2015.

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Peptide-Carrier Conjugation: Methods in Molecular Biology

Hansen, P. R., 2015, Methods in Molecular Biology: Peptide Antibodies. Bind 1348. s. 51-57 7 s.

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Peptide Macrocycles Featuring a Backbone Secondary Amine: A Convenient Strategy for the Synthesis of Lipidated Cyclic and Bicyclic Peptides on Solid Support

Oddo, A., Münzker, L. & Hansen, P. R., 15 maj 2015, I: Organic Letters. 17, 10, s. 2502-2505 4 s.

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6 Citationer (Scopus)

Rational Design of alpha-helical antimicrobial peptides: DOs and DON’Ts

Uggerhøj, L. E., Poulsen, T. J., Munk, J. K., Fredborg, M., Sondergaard, T. E., Frimodt-Møller, N., Hansen, P. R. & Wimmer, R., 21 dec. 2015, I: ChemBioChem. 16, 2, s. 242–253 12 s.

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45 Citationer (Scopus)

The effect of glycine replacement with flexible ω-amino acids on the antimicrobial and haemolytic activity of an amphipathic cyclic heptapeptide

Oddo, A., Nyberg, N., Frimodt-Møller, N., Thulstrup, P. W. & Hansen, P. R., 18 sep. 2015, I: European Journal of Medicinal Chemistry. 102, s. 574-581 8 s.

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9 Citationer (Scopus)

2014

AMP mimics with bactericidal activity against Staphylococci and Pseudomonas as novel drugs for topical use in veterinary medicine

Greco, I., Damborg, P. P., Guardabassi, L., Nielsen, H. M. & Hansen, P. R., 4 jun. 2014.

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Identification and fine mapping of a linear B cell epitope of human vimentin

Dam, C. E., Houen, G., Hansen, P. R. & Trier, N., 1 sep. 2014, I: Scandinavian Journal of Clinical & Laboratory Investigation. 74, 6, s. 506-514 9 s.

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5 Citationer (Scopus)

Identification of a linear epitope recognized by a monoclonal antibody directed to the heterogeneous nucleoriboprotein A2

Tronstrøm, J., Dragborg, A. H., Hansen, P. R., Houen, G. & Trier, N. H., jan. 2014, I: Protein and Peptide Letters. 21, 1, s. 25-31 7 s.

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4 Citationer (Scopus)

Paul Robert Hansen

Publikation

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