Paul Robert Hansen

Research output

Research output per year 1995 2008 2013 2015 2019 2019

• 82 Journal article
• 36 Poster
• 11 Article in proceedings
• 11 Conference abstract for conference
• 19 More
  • 6 Book chapter
  • 5 Book
  • 2 Paper
  • 2 Review
  • 1 Ph.D. thesis
  • 1 Conference abstract in journal
  • 1 Conference article
  • 1 Other contribution

Research output per year

Research output per year

Search results

• 2014

  Invited Lecture: From Host Defence Peptides to New Antibiotics

  Hansen, P. R., 2014.

  Research output: Contribution to conference › Conference abstract for conference › Research

  • Polypeptide Antibiotic Agent 100%
  • Antimicrobial Agent 95%
  • Peptide 78%
  • Structure-Activity Relationship 77%

• Novel method to identify the optimal antimicrobial peptide in a combination matrix, using anoplin as an example

  Munk, J., Ritz, C., Fliedner, F. P., Frimodt-Møller, N. & Hansen, P. R., Feb 2014, In: Antimicrobial Agents and Chemotherapy. 58, 2, p. 1063-1070 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • anoplin 100%
  • Peptides 28%
  • Hemolysis 11%
  • High Pressure Liquid Chromatography 9%
  • Theoretical Models 8%
  13 Citations (Scopus)

• Pepping up Antibiotics: Industry and academia are turning to antimicrobial peptides and their relatives to find new antibiotics, Andy Extance discovers..

  Hansen, P. R., 1 Oct 2014, Chemistry World.

  Research output: Other contribution › Research

• Protective CD4 T cells targeting cryptic epitopes of Mycobacterium tuberculosis resist infection-driven terminal differentiation

  Woodworth, J., Aagaard, C., Hansen, P. R., Cassidy, J., Agger, E. M. & Andersen, P., 1 Apr 2014, In: The Journal of Immunology. 192, 7, p. 3247-58

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Epitopes 100%
  • Tuberculosis 95%
  • T-Lymphocyte Epitopes 78%
  • T-Lymphocytes 72%
  • Mycobacterium tuberculosis 25%
  53 Citations (Scopus)

• Ring flexibility as a key design feature for cyclic antimicrobial peptides

  Oddo, A., Frimodt-Møller, N. & Hansen, P. R., 4 Jun 2014.

  Research output: Contribution to conference › Poster › Research › peer-review

• Structural features of peptoid-peptide hybrids in lipid-water interfaces

  Uggerhøj, L. E., Munk, J. K., Hansen, P. R., Güntert, P. & Wimmer, R., 25 Aug 2014, In: F E B S Letters. 588, 17, p. 3291–3297 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Peptoids 100%
  • Polypeptide Antibiotic Agent 41%
  • Water 37%
  • Lipids 36%
  • Peptides 35%
  6 Citations (Scopus)
• 2013

  A Minimal Labor Approach to Identifying the Optimal Anoplin Analog using ANOVA.

  Munk, J., Ritz, C., Petrine Fliedner, F., Frimodt-Møller, N. & Hansen, P. R., 2013, Proceedings of the 23rd American Peptide Symposium.

  Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

• A Novel Peptide-Peptoid Hybrid Active Against MRSP Skin Infections

  Greco, I., Damborg, P. P., Guardabassi, L. & Hansen, P. R., 4 Nov 2013.

  Research output: Contribution to conference › Poster › Research › peer-review

• Correlation between centromere protein-F autoantibodies and cancer analyzed by enzyme-linked immunosorbent assay

  Welner, S., Trier, N. H., Morten Frisch, M., Locht, H., Hansen, P. R. & Houen, G., 26 Aug 2013, In: Molecular Cancer. 12, 1, 95.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • centromere protein F 100%
  • Autoantibodies 48%
  • Enzyme-Linked Immunosorbent Assay 37%
  • Neoplasms 17%
  • Antibodies 16%
  12 Citations (Scopus)

• Cyclic peptide inhibitors of the β-sliding clamp in Staphylococcus aureus

  Kjelstrup, S., Hansen, P. M. P., Thomsen, L. E., Hansen, P. R. & Løbner-Olesen, A., 4 Sept 2013, In: P L o S One. 8, 9, 13 p., e72273.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cyclic Peptides 100%
  • Staphylococcus aureus 78%
  • cyclic peptides 72%
  • Peptides 69%
  • Inhibitor 61%
  17 Citations (Scopus)

  2382 Downloads (Pure)

• De novo design of novel cyclic antimicrobial peptides

  Oddo, A., Frimodt-Moller, N. & Hansen, P. R., 7 Jul 2013.

  Research output: Contribution to conference › Poster › Research › peer-review

• Identification and mapping of a linear epitope of centromere protein F using monoclonal antibodies

  Welner, S., Trier, N. H., Houen, G. & Hansen, P. R., Feb 2013, In: Journal of Peptide Science. 19, 2, p. 95-101

  Research output: Contribution to journal › Journal article › Research › peer-review

  • centromere protein F 100%
  • Epitope 54%
  • Epitopes 45%
  • Monoclonal Antibodies 38%
  • Peptides 33%
  9 Citations (Scopus)

• Peptide-peptoid hybrids active against methicillin-resistant Staphylococci and Pseudomonas aeruginosa

  Greco, I., Damborg, P. P., Guardabassi, L., Nielsen, H. M. & Hansen, P. R., 7 Jul 2013.

  Research output: Contribution to conference › Poster › Research › peer-review

• Synthesis of antimicrobial peptoids

  Hansen, P. R. & Munk, J., 2013, Peptide synthesis and applications. 2nd ed. Vol. 1047. p. 151-159 (Methods in Molecular Biology).

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  • Antimicrobial Agent 100%
  • Glycine 62%
  • Bioactivity 51%
  • Nitrogen 42%
  • Peptide 41%
  6 Citations (Scopus)

• Synthetic analogs of anoplin show improved antimicrobial activities

  Munk, J., Uggerhøj, L. E., Poulsen, T. J., Frimodt-Møller, N., Wimmer, R., Nyberg, N. T. & Hansen, P. R., Nov 2013, In: Journal of Peptide Science. 19, 11, p. 669-75

  Research output: Contribution to journal › Journal article › Research › peer-review

  • anoplin 100%
  • Haemolytic 50%
  • Hydrophobicity 37%
  • Antimicrobial Agent 30%
  • Strain 30%
  29 Citations (Scopus)

• The antimicrobial lysine-peptoid hybrid LP5 inhibits DNA replication and induces the SOS response in Staphylococcus aureus

  Gottschalk, S., Ifrah, D., Søndergaard, S. L., Gottlieb, C. T., Cohn, M. T., Hiasa, H., Hansen, P. R., Gram, L., Ingmer, H. & Thomsen, L. E., 2013, In: B M C Microbiology. 13, 8 p., 192.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Peptoids 100%
  • Genetics SOS Response 80%
  • DNA Replication 56%
  • Lysine 54%
  • Staphylococcus aureus 48%
  23 Citations (Scopus)

• The Structure of the Central Side Chain is Crucial for Anoplin Hemolytic Activity

  Munk, J., Thøgersen, L., Uggerhøj, L. E., Wimmer, R., Frimodt-Møller, N., Lindorff-Larsen, K. & Hansen, P. R., 2013, Proceedings of the 23rd American Peptide Symposium. Lebl, M. (ed.). American Peptide Society

  Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  • Haemolytic 100%
• 2012

  Antimikrobielle peptider: et nyt våben mod multiresistente bakterier

  Munk, J., Hansen, P. R. & Franzyk, H., 2012, In: Lægemiddelforskning. 2012, p. 9-11

  Research output: Contribution to journal › Journal article › Communication

• Cross-reactivity of a human IgG1 anticitrullinated fibrinogen monoclonal antibody to a citrullinated profilaggrin peptide

  Trier, N. H., Leth, M. L., Hansen, P. R. & Houen, G., 31 Dec 2012, In: Protein Science. 21, 12, p. 1929-1941

  Research output: Contribution to journal › Journal article › Research › peer-review

  • filaggrin 100%
  • Fibrinogen 66%
  • Immunoglobulin G 52%
  • Monoclonal Antibodies 50%
  • Peptides 44%
  19 Citations (Scopus)

• Cytotoxicity and in vivo efficacy of a novel antimicrobial peptoid against Staphylococcus pseudintermedius

  Damborg, P. P., Skindersø, M. E., Hansen, P. R., Bahnsen, J. S., Nielsen, H. M. & Guardabassi, L., Aug 2012.

  Research output: Contribution to conference › Poster › Research › peer-review

• Fine mapping of a monoclonal antibody to the N-Methyl D-aspartate receptor reveals a short linear epitope

  Amrutkar, S. D., Trier, N. H., Hansen, P. R. & Houen, G., 2012, In: Journal of Peptide Science. 98, 6, p. 567-575 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Epitope 100%
  • N-Methyl-D-Aspartate Receptors 98%
  • Epitopes 84%
  • Monoclonal Antibodies 71%
  • Peptides 62%
  13 Citations (Scopus)

• Identification of continuous epitopes of HuD antibodies related to paraneoplastic diseases/small cell lung cancer

  Trier, N. H., Hansen, P. R., Vedeler, C. A., Somnier, F. E. & Houen, G., 29 Feb 2012, In: Journal of Neuroimmunology. 243, 1, p. 25-33 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Small Cell Lung Carcinoma 100%
  • RNA Recognition Motif 91%
  • Epitopes 77%
  • human ELAVL4 protein 70%
  • Peptides 57%
  19 Citations (Scopus)

• Production and characterization of peptide antibodies

  Trier, N. H., Hansen, P. R. & Houen, G., Feb 2012, In: Methods. 56, 2, p. 136-144 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Peptides 100%
  • Peptide 90%
  • Antibodies 86%
  • Immunization 29%
  • Antibody Formation 23%
  49 Citations (Scopus)
• 2011

  Evaluation of 4-[¹⁸F]fluorobenzoyl-FALGEA-NH₂ as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer

  Denholt, C. L., Binderup, T., Stockhausen, M-T., Poulsen, H. S., Spang-Thomsen, M., Hansen, P. R., Gillings, N. M. & Kjær, A., May 2011, In: Nuclear Medicine and Biology. 38, 4, p. 509-515 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • 4-fluorobenzoyl-phenylalanyl-alanyl-leucyl-glycyl-glutamyl-alaninamide 100%
  • epidermal growth factor receptor VIII 62%
  • ErbB Receptors 36%
  • Positron-Emission Tomography 36%
  • Mutation 21%
  12 Citations (Scopus)

• Fast and efficient characterization of an anti-gliadin monoclonal antibody epitope related to celiac disease using resin-bound peptides

  Petersen, N. H., Hansen, P. R. & Houen, G., 28 Feb 2011, In: Journal of Immunological Methods. 365, 1-2, p. 174-182 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gliadin 100%
  • Celiac Disease 78%
  • Epitopes 61%
  • Monoclonal Antibodies 52%
  • Peptides 45%
  13 Citations (Scopus)

• Identification of linear epitopes of HuD antibodies related to paraneoplastic diseases/small cell lung cancer

  Trier, N. H., Hansen, P. R. & Houen, G., 2011. 1 p.

  Research output: Contribution to conference › Poster › Research

• Peptoid inhibits essential cellular functions through unspecific binding to DNA in S. aureus

  Gottschalk, S., Søndergaard, S. L., Hansen, P. R., Ifrah, D., Ingmer, H. & Thomsen, L. E., 2011. 1 p.

  Research output: Contribution to conference › Poster › Research

• The interaction between calreticulin and immunoglobulin G and immunoglobulin Y

  Møllegaard, K. M., Duus, K., Træholt, S. D., Thaysen-Andersen, M., Liu, Y., Palma, A. S., Feizi, T., Hansen, P. R., Højrup, P. & Houen, G., Jul 2011, In: B B A - Proteins and Proteomics. 1814, 7, p. 889-899 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • IgY 100%
  • Calreticulin 87%
  • Immunoglobulin G 47%
  • Peptide 36%
  • Peptides 27%
  6 Citations (Scopus)

• Two novel synthetic peptoids exhibit rapid in vitro killing of methicillin-resistant Staphylococcus pseudintermedius

  Damborg, P. P., Hansen, P. R. & Guardabassi, L., 2011. 1 p.

  Research output: Contribution to conference › Poster › Research

  1193 Downloads (Pure)

• Use of resin-bound peptides for epitope mapping of a monoclonal anti-gliadin antibody related to celiac disease

  Petersen, N. H., Hansen, P. R. & Houen, G., 25 Jun 2011.

  Research output: Contribution to conference › Poster › Research
• 2010

  A Far UV CD study of de novo designed antimicrobial coiled coils upon interaction with model membranes

  Søndergaard, S. L., Kragelund, B. B., Thulstrup, P. W., Brahm, J., Siegumfeldt, H., Frimodt-Møller, N. & Hansen, P. R., 2010, In: Journal of Peptide Science. S2

  Research output: Contribution to journal › Conference abstract in journal › Research

• Antimicrobial activity of small 3-(2 naphthyl)-L-alanine containing peptides

  Hansen, P. R. & Frimodt-Møller, N., 2010, In: Proceedings of the 31st European Peptide Symposium,. 2 p.

  Research output: Contribution to journal › Conference article › Research

• Complex metabolism of aromatic glucosinolates in Pieris rapae caterpillars involving nitrile formation, hydroxylation, demethylation, sulfation, and host plant dependent carboxylic acid formation

  Agerbirk, N., Olsen, C. E., Poulsen, E., Jacobsen, N. & Hansen, P. R., Feb 2010, In: Insect Biochemistry and Molecular Biology. 40, 2, p. 126-137 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Glucosinolates 100%
  • Nitriles 97%
  • Glucosinolate 90%
  • Pieris rapae 84%
  • Arabis 80%
  30 Citations (Scopus)

• Fluorine-18 labelling of a series of potential EGFRvIII targeting peptides with a parallel labelling approach using [¹⁸F]FPyME

  Denholt, C. L., Kuhnast, B., Dollé, F., Hinnen, F., Hansen, P. R., Gillings, N. & Kjær, A., Nov 2010, In: Journal of Labelled Compounds and Radiopharmaceuticals. 53, 13, p. 774-778 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • epidermal growth factor receptor VIII 100%
  • Fluorine-18 89%
  • PEPHC1 peptide 79%
  • Peptides 39%
  • Peptide Receptors 38%
  6 Citations (Scopus)

• Jelleine-I analogues with improved antibacterial activity

  Hansen, P. R., 2010, Peptides - Copenhagen 2010, tales of peptides: proceedings of the 31^th European Peptide Symposium. Lebl, M., Meldal, M., Jensen, K. J. & Hoeg-Jensen, T. (eds.). European Peptide Society, p. 376-377 2 p.

  Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

• Jelleine-I analogues with increased antibacterial activity

  Hansen, P. R., Petersen, J. & Andresen, S., 2010.

  Research output: Contribution to conference › Poster › Research
• 2009

  A combinatorial approach to identify novel peptide targeted against the cancer specific receptor mutation, EFGRvIII.

  Denholdt, C., Hansen, P. R., Pedersen, N., Skovgaard Poulsen, H., Gillings, N. & Kjær, A., 2009.

  Research output: Contribution to conference › Poster › Research

• Comparison of [18F]FBA and [18F]FPyMe as peptide radiolabeling agents of PEPHC1 for PET imaging of EGFRvIII

  Hansen, C. L., Kuhnast, B., Hinnen, F., Dollé, F., Gillings, N., Hansen, P. R. & Kjaer, A., 2009, In: Advances in Experimental Medicine and Biology. 611, p. 405-6 1 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  2 Citations (Scopus)

• Fallaxin analogues with improved antibacterial activity

  Søndergaard, S. L., Frimodt-Møller, N. & Hansen, P. R., 2009, Peptides for Youth: the proceedings of the 20th American Peptide Symposium. Valle, S. D., Escher, E. & Lubell, W. D. (eds.). Springer Science+Business Media, p. 531-532 2 p. (Advances in Experimental Medicine and Biology, Vol. 611).

  Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

• Identification of novel peptide ligands for the cancer-specific receptor mutation EFGRvIII using a mixture-based synthetic combinatorial library

  Denholt, C. L., Hansen, P. R., Pedersen, N., Poulsen, H. S., Gillings, N., Kjær, A., Denholt, C. L., Hansen, P. R., Pedersen, N., Poulsen, H. S., Gillings, N. & Kjaer, A., 2009, In: Biopolymers. 91, 3, p. 201-6 6 p.

  Research output: Contribution to journal › Journal article › Research

  • Epidermal Growth Factor 100%
  • Ligands 76%
  • Peptides 75%
  • Combinatorial Library 70%
  • Receptor Protein-Tyrosine Kinases 61%
  18 Citations (Scopus)

• Interaction of the chaperone calreticulin with proteins and peptides of different structural classes

  Duus, K., Sandhu, N., Jørgensen, C. S., Hansen, P. R., Steinø, A., Thaysen-Andersen, M., Højrup, P. & Houen, G., 1 Nov 2009, In: Protein and Peptide Letters. 16, 11, p. 1414-1423 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Calreticulin 100%
  • Muramidase 47%
  • Ovalbumin 45%
  • Peptides 45%
  • Peptide 41%
  8 Citations (Scopus)

• Peptoid analogs of the antibacterial peptide anoplin

  Meinike, K. & Hansen, P. R., 2009.

  Research output: Contribution to conference › Poster › Research

  821 Downloads (Pure)

• Peptoid analogues of anoplin show antibacterial activity

  Meinike, K. & Hansen, P. R., 2009, In: Protein and Peptide Letters. 16, 9, p. 1006-1011 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  10 Citations (Scopus)

• Trypsin stability of lysine-peptoid hybrids

  Ryge, T. S. & Hansen, P. R., 2009, Peptides for youth: the proceedings of the 20. American Peptide Symposium. Valle, S. D., Escher, E. & Lubell, W. D. (eds.). Springer Science+Business Media, p. 581-582 2 p. (Advances in Experimental Medicine and Biology, Vol. 611).

  Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
• 2008

  Antibacterial activity of a human lysozyme C-terminal fragment conjugated to lipophilic acids

  Ifrah, D. & Hansen, P. R., 2008.

  Research output: Contribution to conference › Poster › Research

• Antigenic profiling of a Chlamydia trachomatis gene-expression library

  Folmann, F., Olsen, A. W., Jensen, K. T., Hansen, P. R., Andersen, P. & Theisen, M., 2008, In: Journal of Infectious Diseases. 197, p. 897-905 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  32 Citations (Scopus)

•  Antimicrobial activities of Lysine-Peptoid Hybrids against Clinically Relevant Bacteria and Fungi

  Ryge, T. S., Frimodt-Møller, N. & Hansen, P. R., 2008.

  Research output: Contribution to conference › Poster › Research

• Antimicrobial activities of twenty lysine-peptoid hybrids against clinically relevant bacteria and fungi

  Ryge, T. S., Frimodt-Møller, N. & Hansen, P. R., 2008, In: Chemotherapy. 54, 2, p. 152-156 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  44 Citations (Scopus)

• Design, Synthesis and Characterization of Novel Antibacterial Lysine-Peptoid Hybrids

  Neerup, T. S. R. & Hansen, P. R., 2008.

  Research output: Contribution to conference › Poster › Research

• Fallaxin: Correlation of antibacterial activity with mean hydrophobicity <H> and mean hydrophobic moment <µ>

  Søndergaard, S. L., Frimodt-Møller, N. & Hansen, P. R., 2008.

  Research output: Contribution to conference › Poster › Research