Individualized Health

2018

Divergent effects of resistance and endurance exercise on plasma bile acids, FGF19, and FGF21 in humans

Morville, T., Sahl, R. E., Trammell, S. A. J., Svenningsen, J. S., Gillum, M. P., Helge, J. W. & Clemmensen, C., 9 Aug 2018, In: JCI Insight. 3, 15, p. 1-13 e122737.

Research output: Contribution to journal › Journal article › Research › peer-review

38 Citations (Scopus)

4 Downloads (Pure)

Effects of 6-month aerobic interval training on skeletal muscle metabolism in middle-aged metabolic syndrome patients

Guadalupe-Grau, A., Fernández-Elías, V. E., Ortega, J. F., Dela, F., Helge, J. W. & Mora-Rodriguez, R., Feb 2018, In: Scandinavian Journal of Medicine & Science in Sports. 28, 2, p. 585-595 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Exercise training increases skeletal muscle mitochondrial volume density by enlargement of existing mitochondria and not de novo biogenesis

Lundby, A-K. M., Jacobs, R. A., Gehrig, S., de Leur, J., Hauser, M., Bonne, T. C., Flück, D., Dandanell, S., Kirk, N., Kaech, A., Ziegler, U., Larsen, S. & Lundby, C., 2018, In: Acta Physiologica (Print). 222, 1, 14 p., e12905.

Research output: Contribution to journal › Journal article › Research › peer-review

54 Citations (Scopus)

Fitness and health benefits of team handball training for young untrained women - A cross-disciplinary RCT on physiological adaptations and motivational aspects

Hornstrup, T., Wikman, J. M., Fristrup, B., Póvoas, S., Helge, E. W., Nielsen, S. H., Helge, J. W., Andersen, J. L., Nybo, L. & Krustrup, P., Apr 2018, In: Journal of Sport and Health Science. 7, 2, p. 139-148 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

109 Downloads (Pure)

Football training over 5 years is associated with preserved femoral bone mineral density in men with prostate cancer

Uth, J., Fristrup, B., Haahr, R. D., Brasso, K., Helge, J. W., Rørth, M. R., Midtgaard, J., Helge, E. W. & Krustrup, P., Aug 2018, In: Scandinavian Journal of Medicine & Science in Sports. 28, Suppl. 1, p. 61-73 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

23 Downloads (Pure)

Four days of bed rest increases intrinsic mitochondrial respiratory capacity in young healthy males

Larsen, S., Lundby, A-K. M., Dandanell, S., Oberholzer, L., Keiser, S., Andersen, A. B., Haider, T. & Lundby, C., 2018, In: Physiological Reports. 6, 18, 9 p., e13793.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

70 Downloads (Pure)

GIP(3-30)NH₂ is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study

Gasbjerg, L. S., Christensen, M. B., Hartmann, B., Lanng, A. R., Sparre-Ulrich, A. H., Gabe, M. B. N., Dela, F., Vilsbøll, T., Holst, J. J., Rosenkilde, M. M. & Knop, F. K., 1 Feb 2018, In: Diabetologia. 61, 2, p. 413-423

Research output: Contribution to journal › Journal article › Research › peer-review

45 Citations (Scopus)

High-intensity interval training changes mitochondrial respiratory capacity differently in adipose tissue and skeletal muscle

Dohlmann, T. L., Hindsø, M., Dela, F., Helge, J. W. & Larsen, S., 1 Sept 2018, In: Physiological Reports. 6, 18, p. 1-11 e13857.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

46 Downloads (Pure)

High-intensity interval training improves insulin sensitivity in older individuals

Søgaard, D., Lund, M. T., Scheuer, C. M., Dehlbaek, M. S., Dideriksen, S. G., Abildskov, C. V., Christensen, K. K., Dohlmann, T. L., Larsen, S., Vigelsø, A. H., Dela, F. & Helge, J. W., Apr 2018, In: Acta Physiologica (Print). 222, 4, e13009.

Research output: Contribution to journal › Journal article › Research › peer-review

38 Citations (Scopus)

Hypertension treatment for older people-navigating between Scylla and Charybdis

Conroy, S. P., Westendorp, R. G. J. & Witham, M. D., 1 Jul 2018, In: Age and Ageing. 47, 4, p. 505-508 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Impact of Thyroid Hormone Therapy on Atherosclerosis in the Elderly With Subclinical Hypothyroidism: A Randomized Trial

Blum, M. R., Gencer, B., Adam, L., Feller, M., Collet, T-H., da Costa, B. R., Moutzouri, E., Dopheide, J., Depairon, M., Sykiotis, G. P., Kearney, P., Gussekloo, J., Westendorp, R., Stott, D. J., Bauer, D. C. & Rodondi, N., 2018, In: The Journal of clinical endocrinology and metabolism. 103, 8, p. 2988-2997 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Impact of Thyroid Hormone Therapy on Bone Health in Older Adults with Subclinical Hypothyroidism: a Randomized Clinical Trial

Rodriguez, E. G., Lowe, A. L., Del Giovane, C., Feller, M., Kearney, P., Gussekloo, J., Mooijaart, S. P., Westendorp, R. G., Stott, D. J., Aeberli, D., Bauer, D., Hans, D. & Rodondi, N., 2018, In: Journal of Bone and Mineral Research. 33, p. 317-318 2 p., 1223.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery

Lund, M. T., Larsen, S., Hansen, M., Courraud, J., Floyd, A. K., Støckel, M., Helge, J. W. & Dela, F., 1 May 2018, In: Acta Physiologica. 223, 1, p. 1-9 e13032.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

NAD⁺ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

Hou, Y., Lautrup, S., Cordonnier, S., Wang, Y., Croteau, D. L., Zavala, E., Zhang, Y., Moritoh, K., O’Connell, J. F., Baptiste, B. A., Stevnsner, T. V., Mattson, M. P. & Bohr, V. A., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 8, p. E1876-E1885

Research output: Contribution to journal › Journal article › Research › peer-review

128 Citations (Scopus)

Obesity leads to impairments in the morphology and organization of human skeletal muscle lipid droplets and mitochondrial networks, which are resolved with gastric bypass surgery-induced improvements in insulin sensitivity

Kristensen, M. D., Petersen, S. M., Møller, K. E., Lund, M. T., Hansen, M., Hansen, C. N., Courraud, J., Helge, J. W., Dela, F. & Prats, C., Dec 2018, In: Acta Physiologica (Print). 224, 4, 15 p., e13100 .

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Peak Fat Oxidation is Not Independently Related to Ironman Performance in Women

Vest, S. D., Frandsen, J., Larsen, S., Dela, F. & Helge, J. W., 2018, In: International Journal of Sports Medicine. 39, 12, p. 916-923

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Perturbations of NAD⁺ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle

Andersen, M. A., Dall, M., Jensen, B. A. H., Prats, C., Madsen, S., Basse, A. L., Graae, A-S., Risis, S., Goldenbaum, J., Quistorff, B., Larsen, S., Vienberg, S. G. & Treebak, J. T., Apr 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 4, p. E377-E395 19 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Sarcopenia, Aging and Prospective Interventional Strategies

Waltz, T. B., Fivenson, E. M., Morevati, M., Li, C., Becker, K. G., Bohr, V. A. & Fang, E. F., 2018, In: Current Medicinal Chemistry. 25, 40, p. 5588-5596 9 p.

Research output: Contribution to journal › Review › peer-review

15 Citations (Scopus)

Simvastatin-Induced Insulin Resistance May Be Linked to Decreased Lipid Uptake and Lipid Synthesis in Human Skeletal Muscle: the LIFESTAT Study

Larsen, S., Vigelsø, A., Dandanell, S., Prats, C., Dela, F. & Helge, J. W., 2018, In: Journal of Diabetes Research. 2018, 7 p., 9257874 .

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Social Relations at Work and Incident Dementia: 29-Years' Follow-Up of the Copenhagen Male Study

Ishtiak-Ahmed, K., Hansen, Å. M., Garde, A. H., Mortensen, E. L., Gyntelberg, F., Phung, T. K. T., Lund, R., Rod, N. H., Prescott, E., Waldemar, G., Westendorp, R. GJ. & Nabe-Nielsen, K., 1 Jan 2018, In: Journal of Occupational and Environmental Medicine. 60, 1, p. 12–18 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

102 Downloads (Pure)

The added value of health indicators to mortality predictions in old age: A systematic review

Kusumastuti, S., Rozing, M. P., Lund, R., Mortensen, E. L. & Westendorp, R. G. J., Nov 2018, In: European Journal of Internal Medicine. 57, p. 7-18 12 p.

Research output: Contribution to journal › Review › peer-review

4 Citations (Scopus)

The combination of cardiorespiratory fitness and muscle strength, and mortality risk

Kim, Y., White, T., Wijndaele, K., Westgate, K., Sharp, S. J., Helge, J. W., Wareham, N. J. & Brage, S., 1 Oct 2018, In: European Journal of Epidemiology. 33, 10, p. 953-964 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

51 Downloads (Pure)

The dynamic life of the glycogen granule

Prats, C., Graham, T. E. & Shearer, J., 11 May 2018, In: Journal of Biological Chemistry. 293, 19, p. 7089-7098

Research output: Contribution to journal › Review › peer-review

47 Citations (Scopus)

Thyroid Stimulating Hormone and Bone Mineral Density: Evidence From a Two-Sample Mendelian Randomization Study and a Candidate Gene Association Study

van Vliet, N. A., Noordam, R., van Klinken, J. B., Westendorp, R. G., Bassett, J. D., Williams, G. R. & van Heemst, D., Jul 2018, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 33, 7, p. 1318-1325 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

36 Downloads (Pure)

Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies

Sahl, R. E., Morville, T., Kraunsøe, R., Dela, F., Helge, J. W. & Larsen, S., 1 Sept 2018, In: Analytical Biochemistry. 556, p. 119-124 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

2017

A high carbohydrate diet remains the evidence based choice for elite athletes to optimise performance

Helge, J. W., 1 May 2017, In: Journal of Physiology. 595, 9, p. 2775-2775

Research output: Contribution to journal › Comment/debate › Research › peer-review

15 Citations (Scopus)

Anthropometry, DXA and leptin reflect subcutaneous but not visceral abdominal adipose tissue by MRI in 197 healthy adolescents

Tinggaard, J., Hagen, C. P., Christensen, A. N., Mouritsen, A., Mieritz, M. G., Wohlfahrt-Veje, C., Helge, J. W., Beck, T. N., Fallentin, E., Larsen, R., Jensen, R. B., Juul, A. & Main, K. M., 1 Oct 2017, In: Pediatric Research. 82, p. 620-628

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

A randomized double-blind study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig cell insufficiency (Einstein-intervention)

Bandak, M., Jørgensen, N., Juul, A., Lauritsen, J., Kreiberg, M., Oturai, P. S., Helge, J. W. & Daugaard, G., 3 Jul 2017, In: B M C Cancer. 17, 8 p., 461.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

72 Downloads (Pure)

Assessment of health status by molecular measures in adults ranging from middle-aged to old: Ready for clinical use?

Waaijer, M. E. C., Westendorp, R. G. J., Goldeck, D., Gunn, D. A., Pawelec, G., Stijntjes, M., Slagboom, P. E. & Maier, A. B., 1 Jan 2017, In: Experimental Gerontology. 87, Part B, p. 175–181 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Bedside manners: How to deal with delirium

Westendorp, R. G. J., 1 Sept 2017, In: Cleveland Clinic Journal of Medicine. 84, 9, p. 699-700 2 p.

Research output: Contribution to journal › Editorial › peer-review

Being Active, Engaged, and Healthy: Older Persons' Plans and Wishes to Age Successfully

Huijg, J. M., van Delden, A. E. Q., van der Ouderaa, F. J. G., Westendorp, R. G. J., Slaets, J. P. J. & Lindenberg, J., 1 Mar 2017, In: Journals of Gerontology. Series B: Psychological Sciences & Social Sciences. 72, 2, p. 228-236 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Cockayne syndrome: Clinical features, model systems and pathways

Karikkineth, A. C., Scheibye-Knudsen, M., Fivenson, E., Croteau, D. L. & Bohr, V. A., 1 Jan 2017, In: Ageing Research Reviews. 33, p. 3-17

Research output: Contribution to journal › Review › peer-review

97 Citations (Scopus)

Corporate culture: research can benefit

Westendorp, R. G. J. & Wewer, U., 15 Feb 2017, In: Nature. 542, 7641, 1 p., 295.

Research output: Contribution to journal › Journal article › Communication

Determination of the exercise intensity that elicits maximal fat oxidation in individuals with obesity

Jørgensen, S. D., Præst, C. B., Søndergård, S. D., Skovborg, C., Dela, F., Larsen, S. & Helge, J. W., Apr 2017, In: Applied Physiology, Nutrition and Metabolism. 42, 4, p. 405-412 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Discrimination ability of comorbidity, frailty, and subjective health to predict mortality in community-dwelling older people: Population based prospective cohort study

Kusumastuti, S., Gerds, T. A., Lund, R., Mortensen, E. L. & Westendorp, R. G. J., Jul 2017, In: European Journal of Internal Medicine. 42, p. 29-38 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

DNA polymerase beta participates in mitochondrial DNA repair

Sykora, P., Kanno, S., Akbari, M., Kulikowicz, T., Baptiste, B. A., Leandro, G. S., Lu, H., Tian, J., May, A., Becker, K. A., Croteau, D. L., Wilson, D. M., Sobol, R. W., Yasui, A. & Bohr, V. A., 1 Aug 2017, In: Molecular and Cellular Biology. 37, 16, e00237-17.

Research output: Contribution to journal › Journal article › Research › peer-review

41 Citations (Scopus)

Effect of APOE ε4 allele on survival and fertility in an adverse environment

van Exel, E., Koopman, J. J. E., Bodegom, D. V., Meij, J. J., Knijff, P. D., Ziem, J. B., Finch, C. E. & Westendorp, R. G. J., 6 Jul 2017, In: PLOS ONE. 12, 7, p. 1-13 13 p., e0179497.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

44 Downloads (Pure)

Effect of intranasally administered insulin on cerebral blood flow and perfusion: a randomized experiment in young and older adults

Akintola, A. A., van Opstal, A. M., Westendorp, R. G., Postmus, I., van der Grond, J. & van Heemst, D., 14 Mar 2017, In: Aging. 9, 3, p. 790-802 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

82 Downloads (Pure)

Effects of intranasal insulin application on the hypothalamic BOLD response to glucose ingestion

van Opstal, A. M., Akintola, A. A., Elst, M. V. D., Westendorp, R. G., Pijl, H., van Heemst, D. & van der Grond, J., 1 Dec 2017, In: Scientific Reports. 7, p. 1-7 7 p., 13327.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

53 Downloads (Pure)

Exercise training protects against aging-induced mitochondrial fragmentation in mouse skeletal muscle in a PGC-1α dependent manner

Halling, J. F., Jørgensen, S. R., Olesen, J., Prats Gavalda, C. & Pilegaard, H., 1 Oct 2017, In: Experimental Gerontology. 96, p. 1-6 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

Genome instability in Alzheimer disease

Hou, Y., Song, H., Croteau, D. L., Akbari, M. & Bohr, V. A., 1 Jan 2017, In: Mechanisms of Ageing and Development. 161, part A, p. 83-94 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

44 Citations (Scopus)

How is Change in Physical Health Status Reflected by Reports of Nurses and Older People Themselves?

Puvill, T., Lindenberg, J., Slaets, J. P. J., de Craen, A. J. M. & Westendorp, R. G. J., 1 Apr 2017, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 72, 4, p. 579–585 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Influence of maximal fat oxidation on long-term weight loss maintenance in humans

Dandanell, S., Husted, K., Amdisen, S., Vigelso, A., Dela, F., Larsen, S. & Helge, J. W., Jul 2017, In: Journal of Applied Physiology. 123, 1, p. 267-274 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Insulin sensitivity in relation to fat distribution and plasma adipocytokines among abusers of anabolic androgenic steroids

Rasmussen, J. J., Schou, M., Selmer, C., Johansen, M. L., Gustafsson, F., Frystyk, J., Dela, F., Faber, J. & Kistorp, C., Sept 2017, In: Clinical Endocrinology. 87, 3, p. 249-256 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice

Fang, E. F., Palikaras, K., Sun, N., Fivenson, E. M., Spangler, R. D., Kerr, J. S., Cordonnier, S. A., Hou, Y., Dombi, E., Kassahun, H., Tavernarakis, N., Poulton, J., Nilsen, H. & Bohr, V. A., 22 Nov 2017, In: Journal of Visualized Experiments. 129, e56301.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Is there evidence for a limit to human lifespan?

Rozing, M. P., Kirkwood, T. B. L. & Westendorp, R. G. J., 28 Jun 2017, In: Nature. 546, 7660, p. E11-E12 2 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

17 Citations (Scopus)

Is there plasticity in mitochondrial cristae density with endurance training?

Larsen, S., Helge, J. W. & Dela, F., 1 May 2017, In: Journal of Physiology. 595, 9, p. 2985-2985 1 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

3 Citations (Scopus)

Lack of effect of prolonged treatment with liraglutide on cardiac remodeling in rats after acute myocardial infarction

Kyhl, K., Lønborg, J., Hartmann, B., Kissow, H., Poulsen, S. S., Ali, H. E., Kjær, A., Dela, F., Engstrøm, T. & Treiman, M., Jul 2017, In: Peptides. 93, p. 1-12

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Leydig cell dysfunction, systemic inflammation and metabolic syndrome in long-term testicular cancer survivors

Bandak, M., Jørgensen, N., Juul, A., Lauritsen, J., Oturai, P. S., Mortensen, J., Hojman, P., Helge, J. W. & Daugaard, G., Oct 2017, In: European Journal of Cancer. 84, p. 9-17 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Macrophage Area Content and Phenotype in Hepatic and Adipose Tissue in Patients with Obesity Undergoing Roux-en-Y Gastric Bypass

Kristensen, M. D., Lund, M. T., Hansen, M., Poulsen, S. S., Ploug, T., Dela, F., Helge, J. W. & Prats, C., Nov 2017, In: Obesity. 25, 11, p. 1921-1931 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Individualized Health

Research output

Search results