Karla Andrea Frydenvang

Publikation

Publikationer pr. år 1988 2001 2002 2004 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2019 2019

• 97 Tidsskriftartikel
• 1 Bidrag til bog/antologi
• 1 Konferenceabstrakt i tidsskrift
• 1 Review

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2010

  Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101)

  Erichsen, M. N., Huynh, T. H. V., Abrahamsen, B., Bastlund, J. F., Bundgaard, C., Monrad, O., Bekker-Jensen, A., Nielsen, C. W., Frydenvang, K. A., Jensen, A. A. & Bunch, L., 14 okt. 2010, I: Journal of Medicinal Chemistry. 53, 19, s. 7180–7191

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile 100%
  • Excitatory Amino Acid Transporter 1 76%
  • Excitatory Amino Acid 62%
  • Structure-Activity Relationship 50%
  • Neurotransmitter 23%
  85 Citationer (Scopus)

• Syntheses of aza-analogous iso-ergoline scaffolds using carbene mediated C-H insertion

  Krogsgaard-Larsen, N., Begtrup, M., Frydenvang, K. A. & Kehler, J., 20 nov. 2010, I: Tetrahedron. 66, 47, s. 9297-9303

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • carbene 100%
  • Ergolines 90%
  • Carbene 50%
  • Hydrazones 40%
  • Diazo Compound 34%
  7 Citationer (Scopus)

• Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones

  Christensen, M. K., Erichsen, K. D., Trojel-Hansen, C., Tjørnelund, J., Nielsen, S. J., Frydenvang, K. A., Johansen, T. N., Nielsen, B., Sehested, M., Jensen, P. B., Ikaunieks, M., Zaichenko, A., Loza, E., Kalvinsh, I. & Björkling, F., 14 okt. 2010, I: Journal of Medicinal Chemistry. 53, 19, s. 7140-7145 6 s.

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  • Oxyphenisatin Acetate 100%
  • Antiproliferative 98%
  • Antitumor 91%
  • Heterografts 88%
  • Dose 75%
  35 Citationer (Scopus)

• Synthesis and characterization of an epimer of tacrolimus, an immunosuppressive drug

  Skytte, D. M., Frydenvang, K. A., Hansen, L., Nielsen, P. G. & Jaroszewski, J. W., 23 apr. 2010, I: Journal of Natural Products. 73, 4, s. 776-779

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Immunosuppressive Agent 100%
  • Epimerization 88%
  • Macrolide Antibiotic Agent 88%
  • Epimer 88%
  • Tacrolimus 81%
  4 Citationer (Scopus)
• 2009

  At være eller ikke være en antagonist

  Frydenvang, K. A., Naur, P., Gajhede, M. & Kastrup, J. S. J., 2009, I: Lægemiddelforskning. s. 43-45

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Formidling

  2064 Downloads (Pure)

• Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine

  Frydenvang, K. A., Lash, L. L., Naur, P., Postila, P. A., Pickering, D. S., Smith, C. M., Gajhede, M., Sasaki, M., Sakai, R., Pentikäinen, O. T., Swanson, G. T. & Kastrup, J. S., 2009, I: Journal of Biological Chemistry. 284, 21, s. 14219-14229

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  • 2-(2-amino-2-carboxyethyl)-hexahydrofuro(3,2-b)pyran-2-carboxylic acid 100%
  • dysiherbaine 93%
  • Ionotropic Glutamate Receptors 53%
  • Agonist 38%
  • Antagonist 37%
  47 Citationer (Scopus)

• New analogues of epiboxidine incorporating the 4,5-dihydroisoxazole nucleus: synthesis, binding affinity at neuronal nicotinic acetylcholine receptors, and molecular modeling investigations

  Dallanoce, C., Magrone, P., Bazza, P., Grazioso, G., Rizzi, L., Riganti, L., Gotti, C., Clementi, F., Frydenvang, K. A. & De Amici, M., 2009, I: Chemistry & Biodiversity. 6, 2, s. 244-259

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • epiboxidine 100%
  • Acetonitrile Oxide 74%
  • Molecular modeling 62%
  • Nicotinic Receptors 45%
  • Acetylcholine 44%
  13 Citationer (Scopus)

• Structural characterisation and dehydration behaviour of siramesine hydrochloride

  Zimmermann, A., Tian, F., Lopez de Diego, H., Frydenvang, K. A., Rantanen, J. T., Elema, M. R. & Hovgaard, L., 2009, I: Journal of Pharmaceutical Sciences. 98, 10, s. 3596-3607

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  10 Citationer (Scopus)
• 2008

  Microwave-Assisted Ring-Opening of Activated Aziridines with Resin-Bound Amines

  Crestey, F. L. J., Witt, M., Frydenvang, K. A., Stærk, D., Jaroszewski, J. & Franzyk, H., 2008, I: Synfacts. 7, s. 769 1 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning

  32 Citationer (Scopus)

• Microwave-assisted ring-opening of activated aziridines with resin-bound amines

  Crestey, F., Witt, M., Frydenvang, K. A., Stærk, D., Jaroszewski, J. W. & Franzyk, H., 2008, I: Journal of Organic Chemistry. 73, 9, s. 3566-3569 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  32 Citationer (Scopus)

• Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4

  Kasper, C., Frydenvang, K. A., Naur, P., Gajhede, M., Pickering, D. S. & Kastrup, J. S. J., 2008, I: FEBS Letters. 582, 29, s. 4089-4094

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  13 Citationer (Scopus)

• Novel high-affinity and selective biaromatic 4-substituted ¿-hydroxybutyric acid (GHB) analogues as GHB ligands: design, synthesis, and binding studies

  Høg, S., Wellendorph, P., Nielsen, B., Frydenvang, K., Dahl, I. F., Bräuner-Osborne, H., Brehm, L., Frølund, B. & Clausen, R. P., 2008, I: Journal of Medicinal Chemistry. 51, 24, s. 8088-8095

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 4-hydroxybutyric acid 100%
  • Sodium Oxybate 93%
  • Gamma-Aminobutyric Acid 74%
  • Ligands 43%
  • Ligand 27%
  20 Citationer (Scopus)
• 2007

  A tetrazolyl-substituted subtype-selective AMPA receptor agonist

  Vogensen, S. B., Frydenvang, K. A., Greenwood, J. R., Postorino, G., Nielsen, B., Pickering, D. S., Ebert, B., Bølcho, U., Egebjerg, J., Gajhede, M., Kastrup, J. S. J., Johansen, T. N., Clausen, R. P. & Krogsgaard-Larsen, P., 2007, I: Journal of Medicinal Chemistry. 50, 10, s. 2408-2414

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  25 Citationer (Scopus)

• Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid

  Conti, P., Caligiuri, A., Pinto, A., Roda, G., Tamborini, L., Nielsen, B., Madsen, U., Frydenvang, K. A., Colombo, A. & De Micheli, C., 2007, I: European Journal of Medicinal Chemistry. 42, 8, s. 1059-1068

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  24 Citationer (Scopus)
• 2006

  Sesquiterpenes from Thapsia nitida var. meridionalis and Thapsia nitida var. nitida

  Rubal, J. J., Guerra, F. M., Moreno-Dorado, F. J., Jorge, Z. D., Massanet, G. M., Søhoel, H., Smitt, U. W., Frydenvang, K. A., Christensen, S. B., Nielsen, C. & Eriksson, M., 2006, I: Journal of Natural Products. 69, 11, s. 1566-71 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Thapsia 100%
  • Germacrane 80%
  • Sesquiterpenes 63%
  • Sesquiterpene 51%
  • Germacrane Sesquiterpenes 50%
  7 Citationer (Scopus)
• 2005

  Andrastin A and barceloneic acid metabolites, protein farnesyl transferase inhibitors from Penicillium albocoremium: chemotaxonomic significance and pathological implications

  Overy, D. P., Larsen, T. O., Dalsgaard, P. W., Frydenvang, K. A., Phipps, R., Munro, M. H. G. & Christophersen, C., 2005, I: Mycological Research. 109, s. 1243-1249

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Assessment of the combined approach of N-alkylation and salt formation to enhance aqueous solubility of tertiary amines using bupivacaine as a model drug

  Nielsen, A. B., Frydenvang, K. A., Liljefors, T., Buur, A. & Larsen, C., 2005, I: European Journal of Pharmaceutical Sciences. 24, 1, s. 85-93 9 s.

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  • Alkylation 100%
  • Bupivacaine 85%
  • Amines 79%
  • Solubility 75%
  • Salts 66%
  14 Citationer (Scopus)
• 2004

  2-(2,3-Dihydro-1H-indol-3-yl)ethanol: synthesis, separation of enantiomers, and assignment of absolute stereochemistry by X-ray structure analysis

  Frydenvang, K. A., Sommer, M. B., Heckmann, D., Nielsen, O. & Bang-Andersen, B., 2004, I: Chirality. 16, 2, s. 126-30 5 s.

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  • Stereochemistry 100%
  • Enantiomers 93%
  • Phosphate Salt 77%
  • Dihydrogen 58%
  • Ethanol 53%
  1 Citationer (Scopus)

• Aqueous solubility study of salts of benzylamine derivatives and p-substituted benzoic acid derivatives using X-ray crystallographic analysis

  Parshad, H., Frydenvang, K. A., Liljefors, T., Sorensen, H. O. & Larsen, C., 2004, I: International Journal of Pharmaceutics. 269, 1, s. 157-68 12 s.

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  • benzylamine 100%
  • Benzoic Acid 86%
  • Benzylamine 71%
  • Solubility 61%
  • Salts 53%
  17 Citationer (Scopus)

• Carbamoylcholine homologs: synthesis and pharmacology at nicotinic acetylcholine receptors

  Jensen, A. A., Mikkelsen, I. B., Frølund, B., Frydenvang, K., Brehm, L., Jaroszewski, J. W., Bräuner-Osborne, H., Falch, E. & Krogsgaard-Larsen, P., 2004, I: European Journal of Pharmacology. 497, 2, s. 125-37 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Carbachol 100%
  • Nicotinic Receptors 98%
  • N,N-dimethylcarbamate 71%
  • Pharmacology 59%
  • X Ray Crystallography 40%
  8 Citationer (Scopus)

• Design, synthesis, and pharmacological characterization of novel, potent NMDA receptor antagonists

  Conti, P., De Amici, M., Grazioso, G., Roda, G., Barberis Negra, F. F., Nielsen, B., Stensbøl, T. B., Madsen, U., Bräuner-Osborne, H., Frydenvang, K. A., De Sarro, G., Toma, L. & De Micheli, C., 30 dec. 2004, I: Journal of Medicinal Chemistry. 47, 27, s. 6740-8 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • N Methyl Dextro Aspartic Acid Receptor Blocking Agent 100%
  • Ionotropic Glutamate Receptors 89%
  • N-Methyl-D-Aspartate Receptors 66%
  • Stereoisomerism 61%
  • Carboxylic Acids 56%
  20 Citationer (Scopus)

• Psychrophilin A and Cycloaspeptide D, novel cyclic peptides from the psychrotolerant fungus Penicillium ribeum

  Dalsgaard, P. W., Larsen, T. O., Frydenvang, K. A. & Christophersen, C., 2004, I: Journal of Natural Products. 67, 5, s. 878-881

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  46 Citationer (Scopus)
• 2003

  Assessment of drug salt release from solutions, suspensions and in situ suspensions using a rotating dialysis cell

  Parshad, H., Frydenvang, K., Liljefors, T., Cornett, C. & Larsen, C., 2003, I: European Journal of Pharmaceutical Sciences. 19, 4, s. 263-272 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Drug Liberation 100%
  • Salts 89%
  • Suspensions 89%
  • Dialysis 87%
  • Buffers 31%
  18 Citationer (Scopus)

• Rational design, synthesis, and pharmacological evaluation of 2-azanorbornane-3-exo,5-endo-dicarboxylic acid: a novel conformationally restricted glutamic acid analogue

  Bunch, L., Liljefors, T., Greenwood, J. R., Frydenvang, K. A., Bräuner-Osborne, H., Krogsgaard-Larsen, P. & Madsen, U., 2003, I: Journal of Organic Chemistry. 68, 4, s. 1489-95 7 s.

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  • Kainic Acid 100%
  • Borane 72%
  • Glutamic Acid 69%
  • Wilkinson Decarbonylation 32%
  • Hydroboration 26%
  35 Citationer (Scopus)

• Stereostructure-activity studies on agonists at the AMPA and kainate subtypes of ionotropic glutamate receptors

  Johansen, T. N., Greenwood, J. R., Frydenvang, K. A., Madsen, U. & Krogsgaard-Larsen, P., 2003, I: Chirality. 15, 2, s. 167-79 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Ionotropic Glutamate Receptors 100%
  • alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid 92%
  • Kainic Acid 86%
  • Glutamic Acid 78%
  • Agonist 71%
  25 Citationer (Scopus)
• 2002

  2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid: resolution, absolute stereochemistry and enantiopharmacology at glutamate receptors

  Johansen, T. N., Janin, Y. L., Nielsen, B., Frydenvang, K. A., Bräuner-Osborne, H., Stensbøl, T. B., Vogensen, S. B., Madsen, U. & Krogsgaard-Larsen, P., 2002, I: Bioorganic & Medicinal Chemistry. 10, 7, s. 2259-66 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid 100%
  • AMPA Receptors 45%
  • Glutamate Receptors 42%
  • Propionic Acid 42%
  • Agonist 37%
  23 Citationer (Scopus)

• Correlation of aqueous solubility of salts of benzylamine with experimentally and theoretically derived parameters. A multivariate data analysis approach

  Parshad, H., Frydenvang, K. A., Liljefors, T. & Larsen, C. S., 2002, I: International Journal of Pharmaceutics. 237, 1-2, s. 193-207 15 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • benzylamine 100%
  • Benzylamine 71%
  • Solubility 61%
  • Salts 53%
  • Data Analysis 45%
  32 Citationer (Scopus)

• Glutamate receptor ligands: synthesis, stereochemistry, and enantiopharmacology of methylated 2-aminoadipic acid analogs

  Guldbrandt, M., Johansen, T. N., Frydenvang, K. A., Bräuner-Osborne, H., Stensbøl, T. B., Nielsen, B., Karla, R., Santi, F., Krogsgaard-Larsen, P. & Madsen, U., 2002, I: Chirality. 14, 4, s. 351-63 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 2-Aminoadipic Acid 100%
  • Stereochemistry 94%
  • Ligands 67%
  • Glutamate Receptors 56%
  • Acids 46%
  4 Citationer (Scopus)

• Plant analysis by butterflies: occurrence of cyclopentenylglycines in Passifloraceae, Flacourtiaceae, and Turneraceae and discovery of the novel nonproteinogenic amino acid 2-(3'-cyclopentenyl)glycine in Rinorea

  Clausen, V., Frydenvang, K. A., Koopmann, R., Jørgensen, L. B., Abbiw, D. K., Ekpe, P. & Jaroszewski, J. W., 2002, I: Journal of Natural Products. 65, 4, s. 542-7 6 s.

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  • Passifloraceae 100%
  • Salicaceae 96%
  • Plant Analysis 85%
  • Butterflies 70%
  • Glycine 49%
  20 Citationer (Scopus)
• 2001

  Resolution, configurational assignment, and enantiopharmacology at glutamate receptors of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) and demethyl-ACPA

  Johansen, T. N., Stensbøl, T. B., Nielsen, B., Vogensen, S. B., Frydenvang, K. A., Sløk, F. A., Bräüner-Osborne, H., Madsen, U. & Krogsgaard-Larsen, P., 2001, I: Chirality. 13, 9, s. 523-32 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid 100%
  • Propionic acid 70%
  • (S)-ACPA 64%
  • AMPA Receptor Agonist 52%
  • AMPA Receptors 49%
  16 Citationer (Scopus)

• Stereochemistry and molecular pharmacology of (S)-thio-ATPA, a new potent and selective GluR5 agonist

  Stensbøl, T. B., Jensen, H. S., Nielsen, B., Johansen, T. N., Egebjerg, J., Frydenvang, K. A. & Krogsgaard-Larsen, P., 2001, I: European Journal of Pharmacology. 411, 3, s. 245-53 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 2-amino-3-(5-tert-butyl-3-hydroxy-4-isothiazolyl)propionic acid 100%
  • Stereoisomerism 54%
  • Pharmacology 25%
  • AMPA Receptors 18%
  • Gluk2 kainate receptor 6%
  18 Citationer (Scopus)

• Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors

  Madsen, U., Bräuner-Osborne, H., Frydenvang, K. A., Hvene, L., Johansen, T. N., Nielsen, B., Sánchez, C., Stensbøl, T. B., Bischoff, F. & Krogsgaard-Larsen, P., 2001, I: Journal of Medicinal Chemistry. 44, 7, s. 1051-9 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid 100%
  • Glutamic Acid 85%
  • Antagonist 74%
  • propionic acid 71%
  • Propionic Acid 58%
  21 Citationer (Scopus)

• Unprecedented migration of N-alkoxycarbonyl groups in protected pyroglutaminol

  Bunch, L., Norrby, P-O., Frydenvang, K. A., Krogsgaard-Larsen, P. & Madsen, U., 2001, I: Organic Letters. 3, 3, s. 433-5 3 s.

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  • t-butyloxycarbonyl group 100%
  • Ether 51%
  • Cleavage 31%
  • ethers 25%
  • cleavage 23%
  21 Citationer (Scopus)
• 2000

  GABA uptake inhibitors. Design, molecular pharmacology and therapeutic aspects

  Krogsgaard-Larsen, P., Frølund, B. & Frydenvang, K. A., 2000, I: Current Pharmaceutical Design. 6, 12, s. 1193-209 17 s.

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  • (R)-Nipecotic Acid 100%
  • GABA Uptake Inhibitor 86%
  • GABA Uptake Inhibitors 84%
  • gamma-Aminobutyric Acid 47%
  • Guvacine 45%
  88 Citationer (Scopus)

• Resolution, configurational assignment, and enantiopharmacology of 2-amino-3-[3-hydroxy-5-(2-methyl-2H- tetrazol-5-yl)isoxazol-4-yl]propionic acid, a potent GluR3- and GluR4-preferring AMPA receptor agonist

  Vogensen, S. B., Jensen, H. S., Stensbøl, T. B., Frydenvang, K. A., Bang-Andersen, B., Johansen, T. N., Egebjerg, J. & Krogsgaard-Larsen, P., 2000, I: Chirality. 12, 10, s. 705-13 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • AMPA 4 glutamate receptor ionotropic 100%
  • AMPA Receptor Agonist 98%
  • azastene 94%
  • Propionic acid 88%
  • Kainic Acid 79%
  28 Citationer (Scopus)

• UV-guided screening of benzodiazepine producing species in Penicillium

  Ostenfeld Larsen T, Frydenvang, K. A. & Christian Frisvad J, 2000, I: Biochemical Systematics and Ecology. 28, 9, s. 881-886 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Penicillium 100%
  • benzodiazepines 96%
  • auranthine 94%
  • Benzodiazepine 84%
  • Benzodiazepines 75%
  20 Citationer (Scopus)
• 1999

  Selective Inhibitors of Glial GABA Uptake: Synthesis, Absolute Stereochemistry, and Pharmacology of the Enantiomers of 3-Hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole (exo-THPO) and Analogues

  Falch, E., Frølund, B., Perregaard, Sanchez, C., Søkilde, B., Buur, A., Hansen, A., Frydenvang, K. A., Brehm, L., Bolvig, T., Larsson, O. M., Schousboe, A. & Krogsgaard-Larsen, P., 1999, I: Journal of Medicinal Chemistry. 42, s. 5402–5414

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  47 Citationer (Scopus)

• Synthesis and muscarinic receptor pharmacology of a series of 4,5,6,7-tetrahydroisothiazolo[4,5-c]pyridine bioisosteres of arecoline

  Pedersen, H., Bräuner-Osborne, H., Ball, R. G., Frydenvang, K. A., Meier, E., Bøgesø, K. P. & Krogsgaard-Larsen, P., 1999, I: Bioorganic & Medicinal Chemistry. 7, 5, s. 795-809 15 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Arecoline 100%
  • pyridine 75%
  • Parasympathomimetic Agent 73%
  • Muscarinic Receptors 64%
  • Pyridine 41%
  5 Citationer (Scopus)
• 1998

  Antiprotozoal properties of 16,17-dihydrobrachycalyxolide from Vernonia brachycalyx

  Oketch-Rabah, H. A., Brøgger Christensen, S., Frydenvang, K., Dossaji, S. F., Theander, T. G., Cornett, C., Watkins, W. M., Kharazmi, A. & Lemmich, E., 1998, I: Planta Medica. 64, 6, s. 559-62 3 s.

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  • Vernonia 100%
  • Antiplasmodic 81%
  • Germacrane Sesquiterpenes 63%
  • Aerial Plant Components 51%
  • Germacrane 50%
  39 Citationer (Scopus)

• UV-Guided isolation of alantrypinone, a novel Penicillium alkaloid

  Larsen, T. O., Frydenvang, K. A., Frisvad, J. C. & Christophersen, C., 1998, I: Journal of Natural Products. 61, 9, s. 1154-7 4 s.

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  • fumiquinazoline F 100%
  • Fumiquinazoline F 87%
  • Penicillium 55%
  • X-Ray Diffraction 48%
  • Alkaloids 45%
  80 Citationer (Scopus)
• 1997

  Antiprotozoal compounds from Asparagus africanus

  Oketch-Rabah, H. A., Dossaji, S. F., Christensen, S. B., Frydenvang, K., Lemmich, E., Cornett, C., Olsen, C. E., Chen, M., Kharazmi, A. & Theander, T., 1997, I: Journal of Natural Products. 60, 10, s. 1017-22 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • (+)-Nyasol 100%
  • nyasol 74%
  • Sapogenin 66%
  • muzanzagenin 58%
  • Inhibitory Concentration 50 41%
  74 Citationer (Scopus)

• Excitatory amino acid receptor antagonists: resolution, absolute stereochemistry, and pharmacology of (S)- and (R)-2-amino-2-(5-tert-butyl-3-hydroxyisoxazol-4-yl)acetic acid (ATAA)

  Johansen, T. N., Frydenvang, K. A., Ebert, B., Madsen, U. & Krogsgaard-Larsen, P., 1997, I: Chirality. 9, 5-6, s. 529-36 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • N-acetylVal-Nle(7,8)-allatotropin (5-13) 100%
  • Stereochemistry 90%
  • Glutamate Receptor Antagonist 83%
  • N Methyl Dextro Aspartic Acid Receptor Blocking Agent 73%
  • Acetic acid 63%
  10 Citationer (Scopus)

• GABA-A and GABA-B receptor Agonists, Partial Agonists and Modulators. design and Therapeutic Prospects

  Frølund, B., Krogsgaard-Larsen, P., Kristiansen, U., Frydenvang, K. A. & Ebert, B., 1997, I: European Journal of Pharmaceutical Sciences. 4, s. 355–384

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
• 1996

  Conformational analysis of acetylcholine and related choline esters

  Frydenvang, K. A. & Jensen, B., 1996, I: Acta Crystallographica. Section B: Structural Science. 52 ( Pt 1), s. 184-93 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Choline Ester 100%
  • Acetylcholine 64%
  • Choline 64%
  • Mechanics 62%
  • Esters 61%
  15 Citationer (Scopus)

• N-methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid

  Madsen, U., Frydenvang, K. A., Ebert, B., Johansen, T. N., Brehm, L. & Krogsgaard-Larsen, P., 1996, I: Journal of Medicinal Chemistry. 39, 1, s. 183-90 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • N-acetylalanyl-N-methylamide 100%
  • N Methyl Dextro Aspartic Acid Receptor Stimulating Agent 76%
  • (R)-AMAA 50%
  • aspartic acid receptor 50%
  • N-Methylaspartate 45%
  30 Citationer (Scopus)

• Stereospecific GABA-B receptor antagonism

  Frydenvang, K. A., Frølund, B., Kristiansen, U. & Krogsgaard-Larsen, P., 1996, GABA, receptors, transporters and metabolism. Tanaka, C. & Bowery, N. G. (red.). Basel: Birkhäuser Verlag

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review
• 1995

  GABA-B Antagonists: Enantiopharmacology of 5-Amino-4-hydroxy-2-methylvaleric Acid and X-Ray Structure of the Eutomer

  Frydenvang, K. A., Kristiansen, U., Frølund, B., Herdeis, C. & Krogsgaard-Larsen, P., 1995, I: Chirality. 7, s. 526–533

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  3 Citationer (Scopus)
• 1994

  GABAB antagonists: resolution, absolute stereochemistry, and pharmacology of (R)- and (S)-phaclofen

  Frydenvang, K. A., Hansen, J. J., Krogsgaard-Larsen, P., Mitrovic, A., Tran, H., Drew, C. A. & Johnston, G. A., 1994, I: Chirality. 6, 7, s. 583-9 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Stereochemistry 100%
  • phaclofen 90%
  • Baclofen 82%
  • Agonist 51%
  • Antagonist 49%
  20 Citationer (Scopus)

• Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands

  Johansen, T. N., Frydenvang, K. A., Ebert, B., Krogsgaard-Larsen, P. & Madsen, U., 1994, I: Journal of Medicinal Chemistry. 37, 20, s. 3252-62 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • N-acetylalanyl-N-methylamide 100%
  • N-Methyl-D-Aspartic Acid 73%
  • Acidic Amino Acids 63%
  • aspartic acid receptor 50%
  • N-Methylaspartate 45%
  19 Citationer (Scopus)
• 1988

  Structures of acetylcholine picrate and methoxycarbonylcholine picrate hemihydrate

  Frydenvang, K. A., Grønborg, L. & Jensen, B., 1988, I: Acta Crystallographica. Section C: Crystal Structure Communications. 44, Pt 5, s. 841-5 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • picric acid 100%
  • Ammonium Compounds 79%
  • Flotation 69%
  • Acetylcholine 66%
  • Ions 51%
  12 Citationer (Scopus)