Niels Høiby

Research output

Research output per year 1978 2002 2010 2019

• 359 Journal article
• 24 Conference abstract for conference
• 22 Book chapter
• 17 Review
• 44 More
  • 8 Book
  • 7 Net publication - Internet publication
  • 6 Contribution to newspaper - Newspaper article
  • 5 Comment/debate
  • 5 Conference abstract in journal
  • 3 Poster
  • 3 Letter
  • 2 Editorial
  • 2 Patent
  • 1 Comment
  • 1 Paper
  • 1 Contribution to newspaper - Feature article

Research output per year

Research output per year

Search results

• 2008

  Distribution, organization, and ecology of bacteria in chronic wounds

  Kirketerp-Møller, K., Jensen, P. Ø., Fazli, M., Madsen, K. G., Pedersen, J., Moser, C., Tolker-Nielsen, T., Høiby, N., Givskov, M. & Bjarnsholt, T., 1 Aug 2008, In: Journal of Clinical Microbiology. 46, 8, p. 2717-22 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ecology 100%
  • Peptide Nucleic Acids 70%
  • Bacteria 56%
  • Fluorescence In Situ Hybridization 48%
  • Pseudomonas aeruginosa 44%
  317 Citations (Scopus)

• Early aggressive eradication therapy for intermittent Pseudomonas aeruginosa airway colonization in cystic fibrosis patients: 15 years experience

  Hansen, C. R., Pressler, T. & Høiby, N., 2008, In: Journal of Cystic Fibrosis. 7, 6, p. 523-530 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  164 Citations (Scopus)

• Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa

  Skindersoe, M. E., Alhede, M., Phipps, R., Yang, L., Jensen, P. O., Rasmussen, T. B., Bjarnsholt, T., Tolker-Nielsen, T., Høiby, N. & Givskov, M., 1 Oct 2008, In: Antimicrobial Agents and Chemotherapy. 52, 10, p. 3648-63 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Quorum Sensing 100%
  • Pseudomonas aeruginosa 73%
  • Anti-Bacterial Agents 52%
  • Azithromycin 42%
  • Virulence Factors 27%
  254 Citations (Scopus)

• Generel bakteriologi

  Høiby, N., Ciofu, O., Johansen, H. K., Andersen, L. P. & Skinhøj, P., 2008, Klinisk Mikrobiologi og Infektionsmedicin. 3rd ed. København: FADL's Forlag, Vol. 4. p. 21-107 86 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

• Har ny teknologi overflødiggjort Grams farvemetode? Dansk Selskab for Klinisk Mikrobiologi

  Translated title of the contribution: Has the new technology made Gram's staining method redundant? The Danish Society of Clinical MicrobiologyJohansen, H. K., Bjarnsholt, T., Høiby, N. & Dansk Selskab for Klinisk Mikrobiologi, 17 Mar 2008, In: Ugeskrift for læger. 170, 12, p. 1041

  Research output: Contribution to journal › Journal article › Research › peer-review

• In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections

  Yang, L., Haagensen, J. A., Jelsbak, L., Sternberg, C., Høiby, N., Molin, S. & Johansen, H. K., 2008, In: Journal of Bacteriology. 190, 8, p. 2767-2776 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  141 Citations (Scopus)

• Investigation of the algT operon sequence in mucoid and non-mucoid Pseudomonas aeruginosa isolates from 115 Scandinavian patients with cystic fibrosis and in 88 in vitro non-mucoid revertants.

  Ciofu, O., Lee, B., Johannesson, M., Hermansen, N. O., Meyer, P., Høiby, N. & Scandinavian Cystic Fibrosis Study Consortium, 2008, In: Microbiology. 154, Pt 1, p. 103-13 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Operon 100%
  • Cystic Fibrosis 89%
  • Pseudomonas aeruginosa 84%
  • In Vitro Techniques 39%
  • Mutation 34%
  62 Citations (Scopus)

• Klinisk bakteriologi, infektionshygiejne og antibiotikabehandling

  Johansen, H. K., Andersen, L. P., Skinhoj, P., Høiby, N. & Johansen, H. K., 2008, Klinisk Mikrobiologi og Infektionsmedicin. 3rd ed. København: FADL's Forlag, Vol. 6. p. 223-298 75 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

• Klinisk Mikrobiologi og Infektionsmedicin

  Høiby, N. & Skinhøj, P., 2008, København: FADL's Forlag. 563 p.

  Research output: Book/Report › Book › Research › peer-review

• Korte træk af mikrobiologiens historie

  Høiby, N. & Skinhøj, P., 2008, Klinisk Mikrobiologi og Infektionsmedicin. København: FADL's Forlag, Vol. 1. p. 1-4 3 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

• Long-term, low-dose azithromycin treatment reduces the incidence but increases macrolide resistance in Staphylococcus aureus in Danish CF patients

  Hansen, C. R., Pressler, T., Høiby, N. & Johansen, H. K., 2008, In: Journal of Cystic Fibrosis. 8, 1, p. 58-62 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  37 Citations (Scopus)

• Mikrobiologi - alment

  Høiby, N., Høiby, N. (ed.) & Skinhøj, P. (ed.), 2008, Klinisk Mikrobiologi og Infektionsmedicin. København: FADL's Forlag, Vol. 3rd. p. 5-8 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

• Multiple roles of Pseudomonas aeruginosa TBCF10839 PilY1 in motility, transport and infection

  Bohn, Y-S. T., Brandes, G., Rakhimova, E., Horatzek, S., Salunkhe, P., Munder, A., van Barneveld, A., Jordan, D., Bredenbruch, F., Häussler, S., Riedel, K., Eberl, L., Jensen, P. Ø., Bjarnsholt, T., Moser, C., Høiby, N., Tümmler, B. & Wiehlmann, L., 2008, In: Molecular Microbiology. 71, 3, p. 730-47 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Quinolones 100%
  • Pseudomonas aeruginosa 80%
  • Pyocyanine 67%
  • Neutrophils 67%
  • Autolysis 60%
  39 Citations (Scopus)

• Nye retningslinjer for antibiotikadosering til patienter med nedsat nyrefunktion og patienter i haemodialyse

  Translated title of the contribution: New recommendations for antibiotic dosing in patients with renal insufficiency and in patients undergoing haemodialysisMoser, C., Elung-Jensen, T. & Høiby, N., 2008, In: Ugeskrift for læger. 170, 8, p. 629-32 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  1 Citation (Scopus)

• Pseudomonas aeruginosa diversity in distinct paediatric patient groups

  Tramper-Stranders, G. A., Ent, C. K. V. D., Wolfs, T. F., Kimpen, J. L., Fleer, A., Johansen, U., Høiby, N. & Johansen, H. K., 2008, In: Clinical Microbiology and Infection. 14, 10, p. 935-941 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  10 Citations (Scopus)

• Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients.

  Johansen, H. K., Moskowitz, S. M., Ciofu, O., Pressler, T. & Høiby, N., 2008, In: Journal of Cystic Fibrosis. 7, 5, p. 391-7 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Colistin 100%
  • Cystic Fibrosis 76%
  • Pseudomonas aeruginosa 72%
  • Disease Outbreaks 43%
  • Ambulatory Care Facilities 19%
  112 Citations (Scopus)

• Systematisk bakteriologi

  Høiby, N. & Skinhøj, P., 2008, Klinisk Mikrobiologi og Infektionsmedicin. København: FADL's Forlag, Vol. 5. p. 109-222 113 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

• Thermal injury induces impaired function in polymorphonuclear neutrophil granulocytes and reduced control of burn wound infection

  Calum, H. P., Moser, C. E., Jensen, P. Ø., Christoffersen, L., Damlund, D. S. M., Alhede, M., Bjarnsholt, T., Hougen, H. P., Givskov, M., Jacobsen, G. K. & Høiby, N., 2008, In: Clinical and Experimental Immunology. 156, 1, p. 102-110 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Wound Infection 100%
  • Granulocytes 96%
  • Neutrophils 75%
  • Hot Temperature 74%
  • Wounds and Injuries 46%
  45 Citations (Scopus)

• Use of cultivation-dependent and -independent techniques to assess contamination of central venous catheters: a pilot study

  Larsen, M. K., Thomsen, T. R., Moser, C., Nielsen, P. H. & Høiby, N., 2008, In: BMC Clinical Pathology. 8, p. 10 1 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  23 Citations (Scopus)

• Why chronic wounds will not heal: a novel hypothesis

  Bjarnsholt, T., Kirketerp-Møller, K., Jensen, P. Ø., Madsen, K. G., Phipps, R. K., Krogfelt, K., Høiby, N. & Givskov, M., 2008, In: Wound Repair and Regeneration. 16, 1, p. 2-10 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Biofilms 100%
  • Neutrophils 59%
  • Cystic Fibrosis 49%
  • Wounds and Injuries 49%
  • Pseudomonas aeruginosa 47%
  528 Citations (Scopus)
• 2007

  A normally occurring staphylococcus antibody in human serum - Commentary

  Forsgren, A. & Høiby, N., 2007, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 115, 5, p. 540-541 1 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P-aeruginosa lung infection in Cftr(-/-) mice

  Hoffmann, N., Lee, B., Hentzer, M., Rasmussen, T. B., Song, Z. J., Johansen, H. K., Givskov, M. C. & Høiby, N., 2007, In: Antimicrobial Agents and Chemotherapy. 51, 10, p. 3677-3687 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  209 Citations (Scopus)

• Bakteriel meningitis i Danmark 2002 og 2003: Landsdækkende registrering baseret pa laboratoriedata

  Meyer, C. N., Schonheyder, H. C., Bangsborg, J., Nielsen, X. C., Moller, J. K., Molbak, K., Korshin, A., Ronneberg, E., Koster-Rasmussen, R. & Høiby, N., 2007, In: Ugeskrift for læger. 169, 6, p. 503-506 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  13 Citations (Scopus)

• Bakteriel meningitis i Danmark 2002 og 2003. Landsdaekkende registrering baseret på laboratoriedata

  Translated title of the contribution: Bacterial meningitis in Denmark 2002-2003. A nation-wide laboratory-based registrationMeyer, C. N., Schønheyder, H. C., Bangsborg, J. M., Nielsen, X. C., Møller, J. K., Mølbak, K., Korshin, A., Rønneberg, E., Køster-Rasmussen, R., Høiby, N. & Dansk Bakteriel Meningitis Gruppe, 2007, In: Ugeskrift for Laeger. 169, 6, p. 503-6 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Bacterial Meningitides 100%
  • Denmark 85%
  13 Citations (Scopus)

• Christian Grams berømte farvemetode

  Høiby, N., 2007, In: Ugeskrift for læger. 169, 35, p. 2870-

  Research output: Contribution to journal › Journal article › Research › peer-review

• Class a carbapenemases

  Walther-Rasmussen, J. & Høiby, N., 2007, In: Journal of Antimicrobial Chemotherapy. 60, 3, p. 470-482 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  193 Citations (Scopus)

• Cystic fibrosis: coping with resistance

  Ciofu, O., Høiby, N., Gould, I. M. & Meer, J. W. M. V. D., 2007, Antibiotic policies: fighting resistance. Springer, p. 149-174 25 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

• Early rise of anti-Pseudomonas antibodies and a mucoid phenotype of Pseudomonas aeruginosa are risk factors for development of chronic lung infection - A case control study (vol 5, pg 9, 2006)

  Pressler, T., Frederiksen, B., Skov, M., Garred, P., Koch, C. & Høiby, N., 2007, In: Journal of Cystic Fibrosis. 6, 1, p. 79-79

  Research output: Contribution to journal › Journal article › Research › peer-review

• Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.

  Translated title of the contribution: Foreign body infections--biofilms and quorum sensingHøiby, N., Johansen, H. K., Ciofu, O., Jensen, P. Ø., Bjarnsholt, T. & Givskov, M., 2007, In: Ugeskrift for læger. 169, 48, p. 4163-6 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  5 Citations (Scopus)

• Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model

  Christensen, L. D., Moser, C., Jensen, P. Ø., Rasmussen, T. B., Christophersen, L., Kjelleberg, S., Kumar, N., Høiby, N., Givskov, M. & Bjarnsholt, T., 2007, In: Microbiology. 153, Pt 7, p. 2312-20 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Quorum Sensing 100%
  • Foreign Bodies 83%
  • Biofilms 77%
  • Pseudomonas aeruginosa 73%
  • Infections 37%
  101 Citations (Scopus)

• Isolation measures for prevention of infection with respiratory pathogens in cystic fibrosis: a systematic review?

  Høiby, N. & Johansen, H. K., 2007, In: Journal of Hospital Infection. 65, 4, p. 374-375 1 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  7 Citations (Scopus)

• Kittelbogen medicin.dk

  Tvede, M. & Høiby, N., 2007, In: Ugeskrift for læger. 169, 35, p. 2904-

  Research output: Contribution to journal › Journal article › Research › peer-review

• Mannan-binding lectin is a determinant of survival in infective endocarditis

  Tran, C. T., Kjeldsen, K. E., Haunsø, S., Høiby, N., Johansen, H. K. & Christiansen, M., 2007, In: Clinical and Experimental Immunology. 148, 1, p. 101-105 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  14 Citations (Scopus)

• Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients.

  Jelsbak, L., Johansen, H. K., Frost, A-L., Thøgersen, R., Thomsen, L. E., Ciofu, O., Yang, L., Haagensen, J. A. J., Høiby, N. & Molin, S., 2007, In: Infection and Immunity. 75, 5, p. 2214-24 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • cystic fibrosis 100%
  • molecular epidemiology 92%
  • molecular dynamics 92%
  • Molecular Epidemiology 85%
  • Molecular Dynamics Simulation 81%
  170 Citations (Scopus)

• Offentlige forskeres ytringsfrihed er stadig truet

  Høiby, N., 2007, In: Ingenioeren. 43, p. 8-8

  Research output: Contribution to journal › Journal article › Communication

• Pseudomonas aeruginosa infection in cystic fibrosis

  Høiby, N., 2007, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 115, 5, p. 621-628 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa

  Jensen, P. Ø., Bjarnsholt, T., Phipps, R., Rasmussen, T. B., Calum, H., Christoffersen, L., Moser, C., Williams, P., Pressler, T., Givskov, M. & Høiby, N., 2007, In: Microbiology. 153, Pt 5, p. 1329-38 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • rhamnolipid 100%
  • Quorum Sensing 76%
  • Pseudomonas aeruginosa 56%
  • Neutrophils 47%
  • Pseudomonas Infections 18%
  249 Citations (Scopus)

• Reversible gene knockdown in mice using a tight, inducible shRNA expression system - Commentary

  Høiby, N., 2007, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 115, 5, p. 629-631 2 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Silver against Pseudomonas aeruginosa biofilms

  Bjarnsholt, T., Kirketerp-Møller, K., Kristiansen, S., Phipps, R., Nielsen, A. K., Jensen, P. Ø., Høiby, N. & Givskov, M., 2007, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 115, 8, p. 921-8 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Silver 100%
  • Biofilms 91%
  • Pseudomonas aeruginosa 86%
  • Wounds and Injuries 38%
  • Bacteria 36%
  146 Citations (Scopus)
• 2006

  Biological Trojan horse: Antigen 43 provides specific bacterial uptake and survival in human neutrophils

  Fexby, S., Bjarnsholt, T., Jensen, P. Ø., Roos, V., Høiby, N., Givskov, M. & Klemm, P., 2006, In: Infection and Immunity. 75, 1, p. 30-4 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • neutrophils 100%
  • Neutrophils 83%
  • E coli antigen 43 82%
  • antigens 79%
  • cell aggregates 75%
  39 Citations (Scopus)

• Chronic infection with Achromobacter xylosoxidans in cystic fibrosis patients; a retrospective case control study

  Rønne Hansen, C., Pressler, T., Høiby, N. & Gormsen, M., 2006, In: Journal of Cystic Fibrosis. 5, 4, p. 245-51 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Achromobacter denitrificans 100%
  • Cystic Fibrosis 57%
  • Case-Control Studies 47%
  • Infections 27%
  • Cross Infection 22%
  69 Citations (Scopus)

• Early rise of anti-pseudomonas antibodies and a mucoid phenotype of pseudomonas aeruginosa are risk factors for development of chronic lung infection--a case control study

  Pressler, T., Frederiksen, B., Skov, M., Garred, P., Koch, C. & Høiby, N., 2006, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 5, 1, p. 9-15 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  64 Citations (Scopus)

• Effect of aerosolized rhDNase (Pulmozyme (R)) on pulmonary colonization in patients with cystic fibrosis

  Frederiksen, B., Pressler, T., Hansen, A., Koch, C. & Høiby, N., 2006, In: Acta Paediatrica. 95, 9, p. 1070-1074 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  83 Citations (Scopus)

• Evaluating the "Leeds criteria'' for Pseudomonas aeruginosa infection in a cystic fibrosis centre

  Proesmans, M., Balinska-Miskiewicz, W., Dupont, L., Bossuyt, X., Verhaegen, J., Høiby, N. & Boeck, K. D., 2006, In: European Respiratory Journal. 27, 5, p. 937-943 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  66 Citations (Scopus)

• Forekomst og behandling af Clostridium difficile-associeret diarre

  Tvede, M. & Høiby, N., 2006, In: Ugeskrift for læger. 168, 26-32, p. 2579-2580 1 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Increased serum concentration of G-CSF in cystic fibrosis patients with chronic Pseudomonas aeruginosa pneumonia

  Jensen, P. Ø., Moser, C., Kharazmi, A., Presler, T., Koch, C. & Høiby, N., Aug 2006, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 5, 3, p. 145-51 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Granulocyte Colony-Stimulating Factor 100%
  • Cystic Fibrosis 91%
  • Pseudomonas aeruginosa 86%
  • Pneumonia 75%
  • Serum 42%
  31 Citations (Scopus)

• Intranasal immunisation with conjugate vaccine protects mice from systemic and respiratory tract infection with Pseudomonas aeruginosa

  Zuercher, A. W., Horn, M. P., Wu, H., Song, Z. J., Bundgaard, C. J., Johansen, H. K., Høiby, N., Marcus, P. & Lang, A. B., 2006, In: Vaccine. 24, 20, p. 4333-4342 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  25 Citations (Scopus)

• Kernikterus og sulfamethizolbehandling

  Høiby, N., 2006, In: Ugeskrift for læger. 168, 13, p. 1349-1350 1 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• OXA-type carbapenemases

  Walther-Rasmussen, J. & Høiby, N., 2006, In: Journal of Antimicrobial Chemotherapy. 57, 3, p. 373-383 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  321 Citations (Scopus)

• Prehospital diagnostic and therapeutic management of otogenic Streptococcus pneumoniae meningitis

  Ostergaard, C., Høiby, N., Konradsen, H. B. & Samuelsson, S., 2006, In: Scandinavian Journal of Infectious Diseases. 38, 3, p. 172-180 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  9 Citations (Scopus)