Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.

Niels Høiby; Helle Krogh Johansen; Oana Ciofu; Peter Østrup Jensen; Thomas Bjarnsholt; Michael Givskov

Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.

Translated title of the contribution: Foreign body infections--biofilms and quorum sensing

Niels Høiby, Helle Krogh Johansen, Oana Ciofu, Peter Østrup Jensen, Thomas Bjarnsholt, Michael Givskov

Department of Immunology and Microbiology

5 Citations (Scopus)

Abstract

Biofilms are structured consortia of bacteria embedded in self-produced polymer matrix. Biofilms are resistant to antibiotics, disinfectives and phagocytosis. The persistence of foreign body infections is due to biofilms. Chronic P. aeruginosa lung infection in cystic fibrosis patients is a biofilm. Bacteria in biofilms communicate by means of quorum sensing which activates genes for virulence factors. Biofilms can be prevented by antibiotic prophylaxis or early therapy or by quorum sensing inhibitors which make them susceptible to antibiotics and phagocytosis.
Udgivelsesdato: 2007-Nov-26

Translated title of the contribution	Foreign body infections--biofilms and quorum sensing
Original language	Danish
Journal	Ugeskrift for læger
Volume	169
Issue number	48
Pages (from-to)	4163-6
Number of pages	3
ISSN	0041-5782
Publication status	Published - 2007

Cite this

@article{1cd19540ba2011ddae57000ea68e967b,

title = "Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.",

abstract = "Biofilms are structured consortia of bacteria embedded in self-produced polymer matrix. Biofilms are resistant to antibiotics, disinfectives and phagocytosis. The persistence of foreign body infections is due to biofilms. Chronic P. aeruginosa lung infection in cystic fibrosis patients is a biofilm. Bacteria in biofilms communicate by means of quorum sensing which activates genes for virulence factors. Biofilms can be prevented by antibiotic prophylaxis or early therapy or by quorum sensing inhibitors which make them susceptible to antibiotics and phagocytosis. Udgivelsesdato: 2007-Nov-26",

author = "Niels H{\o}iby and Johansen, {Helle Krogh} and Oana Ciofu and Jensen, {Peter {\O}strup} and Thomas Bjarnsholt and Michael Givskov",

note = "Keywords: Anti-Bacterial Agents; Antibiotic Prophylaxis; Biofilms; Drug Resistance, Bacterial; Foreign-Body Reaction; Humans; Infection Control; Pseudomonas Infections; Pseudomonas aeruginosa; Quorum Sensing",

year = "2007",

language = "Dansk",

volume = "169",

pages = "4163--6",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "48",

}

TY - JOUR

T1 - Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.

AU - Høiby, Niels

AU - Johansen, Helle Krogh

AU - Ciofu, Oana

AU - Jensen, Peter Østrup

AU - Bjarnsholt, Thomas

AU - Givskov, Michael

N1 - Keywords: Anti-Bacterial Agents; Antibiotic Prophylaxis; Biofilms; Drug Resistance, Bacterial; Foreign-Body Reaction; Humans; Infection Control; Pseudomonas Infections; Pseudomonas aeruginosa; Quorum Sensing

PY - 2007

Y1 - 2007

N2 - Biofilms are structured consortia of bacteria embedded in self-produced polymer matrix. Biofilms are resistant to antibiotics, disinfectives and phagocytosis. The persistence of foreign body infections is due to biofilms. Chronic P. aeruginosa lung infection in cystic fibrosis patients is a biofilm. Bacteria in biofilms communicate by means of quorum sensing which activates genes for virulence factors. Biofilms can be prevented by antibiotic prophylaxis or early therapy or by quorum sensing inhibitors which make them susceptible to antibiotics and phagocytosis. Udgivelsesdato: 2007-Nov-26

AB - Biofilms are structured consortia of bacteria embedded in self-produced polymer matrix. Biofilms are resistant to antibiotics, disinfectives and phagocytosis. The persistence of foreign body infections is due to biofilms. Chronic P. aeruginosa lung infection in cystic fibrosis patients is a biofilm. Bacteria in biofilms communicate by means of quorum sensing which activates genes for virulence factors. Biofilms can be prevented by antibiotic prophylaxis or early therapy or by quorum sensing inhibitors which make them susceptible to antibiotics and phagocytosis. Udgivelsesdato: 2007-Nov-26

M3 - Tidsskriftartikel

C2 - 18211783

SN - 0041-5782

VL - 169

SP - 4163

EP - 4166

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 48

ER -