Research output per year
Research output per year
Personal profile
Short presentation
Professor of Medical Molecular Microbiology, DMSc, PhD, MSc
EDUCATION:
Master of Science (chemical engineering) from the Technical University of Denmark.
PhD in molecular microbiology from the Technical University of Denmark.
DMSc from the University of Copenhagen.
PREVIOUS EMPLOYMENT:
1995-2001: Post Doc at Department of Microbiology. Technical University of Denmark.
2001-2008: Associate Professor at Department of Systems Biology. Technical University of Denmark.
2008-2012: Associate Professor at Department of International Health, Immunology, and Microbiology. Faculty of Health Sciences. University of Copenhagen.
RESEARCH AREA:
Chronic bacterial infections. Molecular mechanisms involved in microbial biofilm formation and persistence, including regulation of extracellular matrix production, intracellular c-di-GMP-signaling pathways, cell-to-cell signaling, and antibiotic tolerance mechanisms. Identification of drug candidates that can interfere with biofilm formation and antimicrobial tolerance.
BIBLIOMETRICS:
Peer-reviewed articles: >100. Citations: >15.000. H-index: >60. Book chapters: >10.
TEACHING AREA:
Regular teaching in microbiology to undergraduate and graduate students at the Faculty of Health and Medical Sciences, University of Copenhagen.
Keywords
- Faculty of Health and Medical Sciences
- Biomedical Microbiology
- Infection Microbiology
Fingerprint
Dive into the research topics where Tim Tolker-Nielsen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 12 Similar Profiles
-
High levels of cAMP inhibit Pseudomonas aeruginosa biofilm formation through reduction of the c-di-GMP content
Almblad, H., Rybtke, M., Hendiani, S., Andersen, J. B., Givskov, M. & Tolker-Nielsen, T., Mar 2019, In: Microbiology. 165, 3, p. 324-333 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
-
Inactivation of the pgmA Gene in Streptococcus mutans Significantly Decreases Biofilm-Associated Antimicrobial Tolerance
Nilsson, M., Givskov, M., Twetman, S. & Tolker-Nielsen, T., Sept 2019, In: Microorganisms. 7, 9, 12 p., 310.Research output: Contribution to journal › Journal article › Research › peer-review
-
Increased Intracellular Cyclic di-AMP Levels Sensitize Streptococcus gallolyticus subsp. gallolyticus to Osmotic Stress and Reduce Biofilm Formation and Adherence on Intestinal Cells
Teh, W. K., Dramsi, S., Tolker-Nielsen, T., Yang, L. & Givskov, M., 1 Mar 2019, In: Journal of Bacteriology. 201, 6, p. 1-16 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
-
Key players and individualists of Cyclic-di-GMP signaling in burkholderia cenocepacia
Richter, A. M., Fazli, M., Schmid, N., Shilling, R., Suppiger, A., Givskov, M., Eberl, L. & Tolker-Nielsen, T., 1 Jan 2019, In: Frontiers in Microbiology. 10, JAN, 3286.Research output: Contribution to journal › Journal article › Research › peer-review
-
Key Players and Individualists of Cyclic-di-GMP Signaling in Burkholderia cenocepacia
Richter, A. M., Fazli, M., Schmid, N., Shilling, R., Suppiger, A., Givskov, M., Eberl, L. & Tolker-Nielsen, T., 2019, In: Frontiers in Microbiology. 9, 15 p., 3286.Research output: Contribution to journal › Journal article › Research › peer-review
-
Oxidative stress response plays a role in antibiotic tolerance of Streptococcus mutans biofilms
Nilsson, M., Jakobsen, T. H., Givskov, M., Twetman, S. & Tolker-Nielsen, T., Mar 2019, In: Microbiology-Sgm. 165, 3, p. 334-342Research output: Contribution to journal › Journal article › Research › peer-review
-
P. aeruginosa flow-cell biofilms are enhanced by repeated phage treatments but can be eradicated by phage-ciprofloxacin combination: —monitoring the phage–P. aeruginosa biofilms interactions
Henriksen, K., Rørbo, N., Rybtke, M. L., Martinet, M. G., Tolker-Nielsen, T., Høiby, N., Middelboe, M. & Ciofu, O., 2019, In: Pathogens and Disease. 77, 2, 11 p., ftz011.Research output: Contribution to journal › Journal article › Research › peer-review
-
Sub-lethal antimicrobial photodynamic inactivation affects Pseudomonas aeruginosa PAO1 quorum sensing and cyclic di-GMP regulatory systems
Hendiani, S., Rybtke, M. L., Tolker-Nielsen, T. & Kashef, N., 2019, In: Photodiagnosis and Photodynamic Therapy. 27, p. 467-473 7 p.Research output: Contribution to journal › Journal article › Research › peer-review