Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P-aeruginosa lung infection in Cftr(-/-) mice

N. Hoffmann; B. Lee; M. Hentzer; T.B. Rasmussen; Z.J. Song; H.K. Johansen; Michael Christian Givskov; N. Høiby

doi:10.1128/AAC.01011-06

Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P-aeruginosa lung infection in Cftr(-/-) mice

N. Hoffmann, B. Lee, M. Hentzer, T.B. Rasmussen, Z.J. Song, H.K. Johansen, Michael Christian Givskov, N. Høiby

Department of Immunology and Microbiology

209 Citations (Scopus)

Abstract

Udgivelsesdato: 2007/10

Original language	English
Journal	Antimicrobial Agents and Chemotherapy
Volume	51
Issue number	10
Pages (from-to)	3677-3687
Number of pages	10
ISSN	0066-4804
DOIs	https://doi.org/10.1128/AAC.01011-06
Publication status	Published - 2007

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10.1128/AAC.01011-06

Cite this

Hoffmann, N., Lee, B., Hentzer, M., Rasmussen, T. B., Song, Z. J., Johansen, H. K., Givskov, M. C., & Høiby, N. (2007). Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P-aeruginosa lung infection in Cftr(-/-) mice. Antimicrobial Agents and Chemotherapy, 51(10), 3677-3687. https://doi.org/10.1128/AAC.01011-06

Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P-aeruginosa lung infection in Cftr(-/-) mice. / Hoffmann, N.; Lee, B.; Hentzer, M. et al.
In: Antimicrobial Agents and Chemotherapy, Vol. 51, No. 10, 2007, p. 3677-3687.

Research output: Contribution to journal › Journal article › Research › peer-review

Hoffmann, N, Lee, B, Hentzer, M, Rasmussen, TB, Song, ZJ, Johansen, HK, Givskov, MC & Høiby, N 2007, 'Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P-aeruginosa lung infection in Cftr(-/-) mice', Antimicrobial Agents and Chemotherapy, vol. 51, no. 10, pp. 3677-3687. https://doi.org/10.1128/AAC.01011-06

Hoffmann N, Lee B, Hentzer M, Rasmussen TB, Song ZJ, Johansen HK et al. Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P-aeruginosa lung infection in Cftr(-/-) mice. Antimicrobial Agents and Chemotherapy. 2007;51(10):3677-3687. doi: 10.1128/AAC.01011-06

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AU - Lee, B.

AU - Hentzer, M.

AU - Rasmussen, T.B.

AU - Song, Z.J.

AU - Johansen, H.K.

AU - Givskov, Michael Christian

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