Research output per year
Research output per year
Personal profile
Short presentation
Research area:
The biofilm lifestyle dominates in chronic bacterial infections. These biofilm infections are a huge burden for both the patient and the society. Biofilm infections can occur on for example medically inserted implants, in chronic wounds or in the lungs of cystic fibrosis patients.
Characteristic for the chronic biofilm infections is that they show extremely high tolerance towards antibiotics and the host immune system.
I primarily focus on investigating P. aeruginosabiofilms and how to interfere with the development of biofilms or the biofilm tolerance towards antibiotics and/or the host immune system. Currently, I am screening and testing drug candidates with these abilities, using both in vitroand in vivostudies.
Education:
MSc in Engineering (Biotechnology) from the Technical University of Denmark
Ph.D. in medical microbiology from University of Copenhagen
Education/Academic qualification
Introduction to an in vivo Pseudomonas aeruginosa foreign-body infection model
Award Date: 24 Aug 2006
External positions
1 Nov 2006 → 30 Sept 2008
Keywords
- Faculty of Health and Medical Sciences
- Microbiology
- Biofilm
- Quorum sensing
- c-di-GMP
- Pseudomonas aeruginosa
- in vivo models
Fingerprint
Dive into the research topics where Louise Dahl Hultqvist is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 12 Similar Profiles
-
Visualizing biofilm by targeting eDNA with long wavelength probe CDr15
Kwon, H. Y., Kim, J. Y., Liu, X., Lee, J. Y., Yam, J. K. H., Dahl Hultqvist, L., Xu, W., Rybtke, M., Tolker-Nielsen, T., Heo, W., Kim, J. J., Kang, N. Y., Joo, T., Yang, L., Park, S. J., Givskov, M. & Chang, Y. T., 2019, In: Biomaterials Science. 7, 9, p. 3594-3598 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
-
CDy14: A novel biofilm probe targeting exopolysaccharide Psl
Kwon, H. Y., Kim, J. Y., Lee, J. Y., Yam, J. K. H., Hultqvist, L. D., Xu, W., Rybtke, M., Tolker-Nielsen, T., Kim, J. J., Kang, N. Y., Yang, L., Park, S. J., Givskov, M. & Chang, Y. T., 2018, In: Chemical Communications. 54, 84, p. 11865-11868 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
-
Imaging N-acyl homoserine lactone quorum sensing in vivo
Hultqvist, L. D., Alhede, M., Jakobsen, T. H., Givskov, M. & Bjarnsholt, T., 2018, Quorum Sensing: Methods and Protocols. Leoni, L. & Rampion, G. (eds.). Humana Press, Vol. 1673. p. 203-212 10 p. (Methods in Molecular Biology; No. 1673).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
-
Qualitative and Quantitative Determination of Quorum Sensing Inhibition In Vitro
Jakobsen, T. H., Alhede, M., Hultqvist, L. D., Bjarnsholt, T. & Givskov, M., 2018, Quorum Sensing: Methods and Protocols. Springer, Vol. 1673. p. 275-285 11 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
-
In vitro and in vivo generation and characterization of Pseudomonas aeruginosa biofilm-dispersed cells via c-di-GMP manipulation
Chua, S. L., Hultqvist, L. D., Yuan, M., Rybtke, M., Nielsen, T. E., Givskov, M., Tolker-Nielsen, T. & Yang, L., 25 Aug 2015, In: Nature Protocols (Print). 10, 8, p. 1165-80 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
-
Pseudomonas aeruginosa Biofilm Infections: Community Structure, Antimicrobial Tolerance and Immune Response
Rybtke, M., Hultqvist, L. D., Givskov, M. & Tolker-Nielsen, T., 20 Nov 2015, In: Journal of Molecular Biology. 427, 23, p. 3628-45 18 p.Research output: Contribution to journal › Review › peer-review
-
Bacterial biofilm formation and treatment in soft tissue fillers
Alhede, M., Er, O., Eickhardt, S., Kragh, K., Alhede, M., Hultqvist, L. D., Poulsen, S. S., Givskov, M., Christensen, L. H., Høiby, N., Tvede, M. & Bjarnsholt, T., 30 Jan 2014, In: Pathogens and Disease. 70, p. 339-346 8 p.Research output: Contribution to journal › Journal article › Research
-
Clearance of Pseudomonas aeruginosa Foreign-Body Biofilm Infections through Reduction of the Cyclic Di-GMP Level in the Bacteria
Hultqvist, L. D., van Gennip, M., Rybtke, M. T., Wu, H., Chiang, W.-C., Alhede, M., Høiby, N., Nielsen, T., Givskov, M. & Tolker-Nielsen, T., Aug 2013, In: Infection and Immunity. 81, 8, p. 2705-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review