Jacob Wium Bjerrum

Research output

Research output per year 2006 2007 2010 2013 2014 2019

• 19 Journal article
• 2 Review
• 1 Ph.D. thesis
• 1 Book chapter
• 1 More
  • 1 Editorial

Research output per year

Research output per year

Search results

• 2019

  Metabonomics in gastroenterology and hepatology

  Bjerrum, J. T. & Nielsen, O. H., 1 Aug 2019, In: International Journal of Molecular Sciences. 20, 15, 3638.

  Research output: Contribution to journal › Editorial › peer-review
• 2018

  Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

  Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P.J.-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T. & Petersen, A. M. & 7 others, Jensen, K. B., Gögenur, I., Thielsen, P., Seidelin, J. B., Nielsen, O. H., Bjerrum, J. T. & Sandelin, A. G., 1 Dec 2018, In: Nature Communications. 9, 19 p., 1661.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Promoter Region 100%
  • Colon Biopsy 100%
  • Enhancer Region 100%
  • Inflammatory Bowel Disease 100%
  • Transcription Initiation Site 100%
  20 Citations (Scopus)

  120 Downloads (Pure)

• Targeting JAK-STAT signal transduction in IBD

  Soendergaard, C., Bergenheim, F. H., Bjerrum, J. T. & Nielsen, O. H., Dec 2018, In: Pharmacology & Therapeutics. 192, p. 100-111

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Inflammatory Bowel Disease 100%
  • Janus Kinase 100%
  • Signal Transduction 100%
  • Janus Kinase Inhibitor 66%
  • Healthcare Staff 33%
  37 Citations (Scopus)
• 2015

  Integrative Transcriptomic and Metabonomic Molecular Profiling of Colonic Mucosal Biopsies Indicates a Unique Molecular Phenotype for Ulcerative Colitis

  Rantalainen, M., Bjerrum, J. T., Olsen, J., Nielsen, O. H. & Wang, Y., 2 Jan 2015, In: Journal of Proteome Research. 14, 1, p. 479-90 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Mucosal Biopsy 100%
  • Molecular Profiling 100%
  • Molecular Phenotype 100%
  • Transcriptomics 100%
  • Metabonomics 100%
  5 Citations (Scopus)
• 2014

  Assessment of the validity of a multigene analysis in the diagnostics of inflammatory bowel disease

  Bjerrum, J. T., Nyberg, C., Olsen, J. & Nielsen, O. H., May 2014, In: Journal of Internal Medicine. 275, 5, p. 484-93 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Inflammatory Bowel Disease 100%
  • Gene Analysis 100%
  • Ulcerative Colitis 100%
  • Diagnosis 100%
  • Reverse Transcription Polymerase Chain Reaction 100%
  13 Citations (Scopus)

• Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2

  Boyd, M., Coskun, M., Lilje, B., Andersson, R., Hoof, I., Lange, J. B., Dahlgaard, K., Olsen, J., Vitezic, M., Bjerrum, J. T., Seidelin, J. B., Nielsen, O. H., Troelsen, J. & Sandelin, A. G., 1 Dec 2014, In: D N A Research. 21, 6, p. 569-583 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Tumor Necrosis Factor-α 100%
  • Caco-2 100%
  • Epithelial Cell Model 100%
  • Intestinal Epithelial Cells 100%
  • Promoter Region 100%
  9 Citations (Scopus)

  1750 Downloads (Pure)

• Integration of transcriptomics and metabonomics: improving diagnostics, biomarker identification and phenotyping in ulcerative colitis

  Bjerrum, J. T., Rantalainen, M., Wang, Y., Olsen, J. & Nielsen, O. H., Apr 2014, In: Metabolomics. 10, 2, p. 280-290 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ulcerative Colitis 100%
  • Transcriptomics 100%
  • Human Genome 33%
  • Nuclear Magnetic Resonance Spectroscopy 33%
  • Colon 33%
  18 Citations (Scopus)

• Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn's disease and healthy individuals

  Bjerrum, J. T., Wang, Y., Hao, F., Coskun, M., Ludwig, C., Guenther, U. & Nielsen, O. H., Feb 2014, In: Metabolomics. 11, 1, p. 122-133 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Human Fecal Microbiota 100%
  • Crohn's Disease 100%
  • Metabonomics 100%
  • Ulcerative Colitis 100%
  • Healthy Individuals 100%
  118 Citations (Scopus)

• Transcriptional analysis of left-sided colitis, pancolitis, and ulcerative colitis-associated dysplasia

  Bjerrum, J. T., Nielsen, O. H., Riis, L. B., Pittet, V., Mueller, C., Rogler, G. & Olsen, J., 1 Dec 2014, In: Inflammatory Bowel Diseases. 20, 12, p. 2340-2352 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Left-handed 100%
  • Transcriptional Analysis 100%
  • Colitis 100%
  • Ulcerative Colitis 100%
  • Dysplasia 100%
  17 Citations (Scopus)
• 2013

  Colitis ulcerosa

  Translated title of the contribution: Ulcerative colitisNielsen, O. H., Jess, T., Bjerrum, J. T. & Seidelin, J. B., May 2013, In: Ugeskrift for Laeger. 175, 20, p. 1412-6 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ulcerative Colitis 100%
  • Clinician 33%
  • Anemia 33%
  • Colorectal Carcinoma 33%
  • Patient with Ulcerative Colitis 33%
  2 Citations (Scopus)

• miR-20b, miR-98, miR-125b-1*, and let-7e* as new potential diagnostic biomarkers in ulcerative colitis

  Coskun, M., Bjerrum, J. T., Seidelin, J. B., Troelsen, J., Olsen, J. & Nielsen, O. H., 21 Jul 2013, In: World Journal of Gastroenterology. 19, 27, p. 4289-99 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Biological Marker 100%
  • Ulcerative Colitis 100%
  • Diagnosis 100%
  • microRNA 125b 100%
  • MicroRNA 100%
  59 Citations (Scopus)

• Noninfectious & noninflammatory bowel disease colitis

  Nielsen, O. H., Bjerrum, J. T. & Seidelin, J. B., 1 Mar 2013, Advances in the Management of Inflammatory Bowel Disease. Future Medicine Ltd., p. 33-49 17 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

• Recent advances using immunomodulators for inflammatory bowel disease

  Nielsen, O. H., Bjerrum, J. T., Herfarth, H. & Rogler, G., Jun 2013, In: British Journal of Clinical Pharmacology. Supplement. 53, 6, p. 575-588 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Immunomodulator 100%
  • Inflammatory Bowel Disease 100%
  • Recent Advances 100%
  • Immunomodulating Agent 100%
  • Mercaptopurine 66%
  30 Citations (Scopus)
• 2010

  Genome-wide Gene Expression Analysis of Mucosal Colonic Biopsies and Isolated Colonocytes Suggests a Continuous Inflammatory State in the Lamina Propria of Patients with Quiescent Ulcerative Colitis

  Bjerrum, J. T., Hansen, M., Olsen, J., Nielsen, O. H., Bjerrum, J. T., Hansen, M., Olsen, J. & Nielsen, O. H., 2010, In: Inflammatory Bowel Diseases. 16, 6, p. 999-1007 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Inflammatory State 100%
  • Genome-wide Expression 100%
  • Gene Expression Analysis 100%
  • Colonocytes 100%
  • Ulcerative Colitis 100%
  25 Citations (Scopus)

• IL-33 is upregulated in colonocytes of ulcerative colitis

  Seidelin, J. B., Bjerrum, J. T., Coskun, M., Widjaya, B., Vainer, B., Nielsen, O. H., Seidelin, J. B., Bjerrum, J. T., Coskun, M., Widjaya, B., Vainer, B. & Nielsen, O. H., 18 Jan 2010, In: Immunology Letters. 128, 1, p. 80-5 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ulcerative Colitis 100%
  • Interleukin-33 (IL-33) 100%
  • Interleukin-1 20%
  • Cytokine Response 13%
  • Caspase 1 13%
  110 Citations (Scopus)

• Metabonomics in Ulcerative Colitis: Diagnostics, Biomarker Identification, And Insight into the Pathophysiology

  Bjerrum, J. T., Nielsen, O. H., Hao, F., Tang, H., Nicholson, J. K., Wang, Y., Olsen, J., Bjerrum, J. T., Nielsen, O. H., Shen, H., Tang, H. R., Nicholson, J. B., Wang, L. & Olsen, J., 5 Feb 2010, In: Journal of Proteome Research. 9, 2, p. 954-962 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Diagnostic Biomarker 100%
  • Metabonomics 100%
  • Pathophysiology 100%
  • Ulcerative Colitis 100%
  • Biological Marker 100%
  118 Citations (Scopus)

• Transcriptomics, metabonomics, and ulcerative colitis

  Bjerrum, J. T., 2010

  Research output: Book/Report › Ph.D. thesis
• 2009

  Diagnosis of ulcerative colitis before onset of inflammation by multivariate modeling of genome-wide gene expression data

  Olsen, J., Gerds, T. A., Seidelin, J. B., Csillag, C., Bjerrum, J. T., Troelsen, J. T. & Nielsen, O. H., 2009, In: Inflammatory Bowel Diseases. 15, 7, p. 1032-8 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Genome-wide Expression 100%
  • Gene Expression Data 100%
  • Multivariate Modeling 100%
  • Ulcerative Colitis 100%
  • Inflammation 100%
  71 Citations (Scopus)

• Influence of smoking on colonic gene expression profile in Crohn's disease

  Nielsen, O. H., Bjerrum, J. T., Csillag, C., Nielsen, F. C. & Olsen, J., 2009, In: PLoS ONE. 4, 7, p. e6210

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gene Expression 100%
  • Smoking 100%
  • Crohn's Disease 100%
  • Colonic Gene Expression 100%
  • RING Finger Protein 23%
  24 Citations (Scopus)
• 2008

  Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications.

  Bjerrum, J. T., Nielsen, O. H., Wang, Y. L. & Olsen, J., 2008, In: Nature Clinical Practice Gastroenterology & Hepatology. 5, 6, p. 332-43 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gastroenterology 100%
  • Potential Clinical Applications 100%
  • Metabonomics 100%
  • Transcriptomics 100%
  • Nutrition 100%
  22 Citations (Scopus)
• 2007

  Azathioprin og 6-mercaptopurin som vedligeholdelsesbehandling ved colitis ulcerosa: Gennemgang af Cochrane-review

  Bjerrum, J. E. & Nielsen, O. H., 12 Oct 2007, In: Ugeskrift for Laeger. 169, 50, p. 4341-4344 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• CARD15 status and familial predisposition for Crohn's disease and colonic gene expression

  Csillag, C., Nielsen, O. H., Borup, R., Olsen, J., Bjerrum, J. T. & Nielsen, F. C., 2007, In: Digestive Diseases and Sciences. 52, 8, p. 1783-1789 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  10 Citations (Scopus)

• TNF-α-antistofbehandling og remissionsinduktion ved colitis ulcerosa: Gennemgang af et Cochrane-review

  Bjerrum, J. T., Munck, L. K., Krogh-Madsen, M. & Nielsen, O. H., 26 Feb 2007, In: Ugeskrift for Laeger. 169, 9, p. 792-795 4 p.

  Research output: Contribution to journal › Review › peer-review

  1 Citation (Scopus)
• 2006

  Perioperativ blodtransfusion og recidiv af karcinom i colon og rectum: Gennemgang af et Cochrane-review

  Bjerrum, J. T., Jensen, L. S. & Nielsen, O. H., 21 Aug 2006, In: Ugeskrift for Laeger. 168, 34, 1 p.

  Research output: Contribution to journal › Review › peer-review

  3 Citations (Scopus)