Abigail Mackey

2020

Neuromuscular Electrical Stimulation Preserves Leg Lean Mass in Geriatric Patients

Karlsen, A., Cullum, C. K., Norheim, K. L., Scheel, F. U., Zinglersen, A. H., Vahlgren, J., Schjerling, P., Kjaer, M. & Mackey, A. L., 1 Apr 2020, In: Medicine & Science in Sports & Exercise. Publish Ahead of Print

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

2019

Age and prior exercise in vivo determine the subsequent in vitro molecular profile of myoblasts and non-myogenic cells derived from human skeletal muscle

Bechshøft, C. J. L., Jensen, S. M., Schjerling, P., Andersen, J. L., Svensson, R. B., Eriksen, C. S., Mkumbuzi, N. S., Kjaer, M. & Mackey, A. L., Jun 2019, In: American Journal of Physiology: Cell Physiology. 316, 6, p. C898-C912

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise

Ziegler, A. K., Damgaard, A., Mackey, A. L., Schjerling, P., Magnusson, P., Olesen, A. T., Kjaer, M. & Scheele, C., 1 Dec 2019, In: Scientific Reports. 9, 11 p., 12069.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

17 Downloads (Pure)

Behandling af akutte muskelskader

Translated title of the contribution: Treatment of acute muscle injuriesBayer, M. L., Mackey, A., Magnusson, S. P., Krogsgaard, M. R. & Kjær, M., 18 Feb 2019, In: Ugeskrift for Laeger. 181, 8, 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Downloads (Pure)

Lack of muscle fibre hypertrophy, myonuclear addition, and satellite cell pool expansion with resistance training in 83-94-year-old men and women

Karlsen, A., Bechshøft, R. L., Malmgaard-Clausen, N. M., Andersen, J. L., Schjerling, P., Kjaer, M. & Mackey, A. L., 3 Mar 2019, In: Acta Physiologica. 227, ja, e13271.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Molecular indicators of denervation in ageing human skeletal muscle

Soendenbroe, C., Heisterberg, M. F., Schjerling, P., Karlsen, A., Kjaer, M., Andersen, J. L. & Mackey, A. L., 1 Oct 2019, In: Muscle & Nerve.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation

Ziegler, A. K., Jensen, S. M., Schjerling, P., Mackey, A. L., Andersen, J. L. & Kjaer, M., 1 Jul 2019, In: Experimental Gerontology. 121, p. 19-32

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

The influence of direct and indirect fibroblast cell contact on human myogenic cell behaviour and gene expression in vitro

Bechshøft, C. J. L., Schjerling, P., Kjaer, M. & Mackey, A. L., 2019, In: Journal of Applied Physiology. 127, 2, p. 342-355

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

The influence of fibrillin‐1 and physical activity upon tendon tissue morphology and mechanical properties in mice

Tran, P. H. T., Skrba, T., Wondimu, E., Galatioto, G., Svensson, R. B., Olesen, A. T., Mackey, A. L., Magnusson, S. P., Ramirez, F. & Kjaer, M., 1 Nov 2019, In: Physiological Reports. 7, 21, 9 p., e14267 .

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

2 Downloads (Pure)

2018

Effect of Losartan on the Acute Response of Human Elderly Skeletal Muscle to Exercise

Heisterberg, M. F., Andersen, J. L., Schjerling, P., Bülow, J., Lauersen, J. B., Roeber, H. L., Kjaer, M. & Mackey, A. L., Feb 2018, In: Medicine and Science in Sports and Exercise. 50, 2, p. 225–235

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

Kristensen, D. M., Desdoits-Lethimonier, C., Mackey, A. L., Dalgaard, M. D., De Masi, F., Munkbøl, C. H., Styrishave, B., Antignac, J.-P., Le Bizec, B., Platel, C., Hay-Schmidt, A., Jensen, T. K., Lesné, L., Mazaud-Guittot, S., Kristiansen, K., Brunak, S., Kjaer, M., Juul, A. & Jégou, B., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 4, p. e715-e724 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

50 Citations (Scopus)

165 Downloads (Pure)

Integrated method for quantitative morphometry and oxygen transport modeling in striated muscle

Al-Shammari, A. A., Kissane, R. W. P., Holbek, S., Mackey, A. L., Andersen, T. R., Gaffney, E. A., Kjær, M. & Egginton, S., 29 Sept 2018, In: Journal of Applied Physiology. 126, 3, p. 544-557 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Losartan has no additive effect on the response to heavy resistance exercise in human elderly skeletal muscle

Heisterberg, M. F., Andersen, J. L., Schjerling, P., Lund, A., Dalskov, S., Overgård Jønsson, A., Warming, N., Fogelstrøm, M., Kjaer, M. & Mackey, A. L., Nov 2018, In: Journal of Applied Physiology. 125, 5, p. 1536-1554 19 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Remodeling of muscle fibres approaching the human myotendinous junction

Jakobsen, J. R., Jakobsen, N. R., Mackey, A. L., Koch, M., Kjaer, M. & Krogsgaard, M. R., Aug 2018, In: Scandinavian Journal of Medicine & Science in Sports. 28, 8, p. 1859-1865

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

2017

Composition and adaptation of human myotendinous junction and neighboring muscle fibers to heavy resistance training

Jakobsen, J. R., Mackey, A. L., Knudsen, A. B., Kjaer, M. & Krogsgaard, M. R., Dec 2017, In: Scandinavian Journal of Medicine & Science in Sports. 27, 12, p. 1547–1559

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Connective tissue regeneration in skeletal muscle after eccentric contraction-induced injury

Mackey, A. L. & Kjaer, M., Mar 2017, In: Journal of Applied Physiology. 122, 3, p. 533-540 8 p.

Research output: Contribution to journal › Review › peer-review

19 Citations (Scopus)

Human skeletal muscle fibroblasts stimulate in vitro myogenesis and in vivo muscle regeneration

Mackey, A. L., Magnan, M., Chazaud, B. & Kjaer, M., 1 Aug 2017, In: The Journal of Physiology. 595, 15, p. 5115-5127 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

33 Citations (Scopus)

Improved skeletal muscle mass and strength after heavy strength training in very old individuals

Bechshøft, R. L., Malmgaard-Clausen, N. M., Gliese, B., Beyer, N., Mackey, A. L., Andersen, J. L., Kjær, M. & Holm, L., 1 Jun 2017, In: Experimental Gerontology. 92, p. 96-105 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

Skeletal muscle morphology, protein synthesis and gene expression in Ehlers Danlos Syndrome

Nygaard, R. H., Jensen, J. K., Voermans, N. C., Heinemeier, K. M., Schjerling, P., Holm, L., Agergaard, J., Mackey, A. L., Andersen, J. L., Remvig, L. & Kjaer, M., 1 Aug 2017, In: Journal of Applied Physiology. 123, 2, p. 482-488

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Skeletal muscle morphology and regulatory signalling in endurance-trained and sedentary individuals: The influence of ageing

Mikkelsen, U. R., Agergaard, J., Couppé, C., Grosset, J. F., Karlsen, A., Magnusson, S. P., Schjerling, P., Kjaer, M. & Mackey, A., 1 Jul 2017, In: Experimental Gerontology. 93, p. 54-67

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

The breaking and making of healthy adult human skeletal muscle in vivo

Mackey, A. L. & Kjaer, M., 7 Nov 2017, In: Skeletal Muscle. 7, 18 p., 24.

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

191 Downloads (Pure)

2016

Activation of satellite cells and the regeneration of human skeletal muscle are expedited by ingestion of nonsteroidal anti-inflammatory medication

Mackey, A. L., Rasmussen, L. K., Kadi, F., Schjerling, P., Helmark, I. C., Ponsot, E., Aagaard, P., Durigan, J. L. Q. & Kjaer, M., Jun 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 6, p. 2266-2281

Research output: Contribution to journal › Journal article › Research › peer-review

47 Citations (Scopus)

Muscle satellite cell content and mRNA signaling in germ cell cancer patients: effects of chemotherapy and resistance training

Christensen, J. F., Schjerling, P., Daugaard, G., Rørth, M. & Mackey, A. L., 2016, In: Acta Oncologica. 55, 9-10, p. 1246-1250 5 p.

Research output: Contribution to journal › Comment/debate › Research

388 Citations (Scopus)

2015

Fiber type specific response of skeletal muscle satellite cells to high-intensity resistance training in dialysis patients

Molsted, S., Andersen, J. L., Harrison, A. P., Eidemak, I. & Mackey, A., Nov 2015, In: Muscle & Nerve. 52, 5, p. 736-745 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Matters of fiber size and myonuclear domain: does size matter more than age?

Karlsen, A., Couppé, C., Andersen, J. L., Mikkelsen, U. R., Nielsen, R. H., Magnusson, S. P., Kjaer, M. & Mackey, A., 1 Dec 2015, In: Muscle & Nerve. 52, 6, p. 1040-1046 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

The human myotendinous junction: An ultrastructural and 3D analysis study

Knudsen, A. B., Larsen, M., Mackey, A., Hjort, M., Hansen, K. K., Qvortrup, K., Kjaer, M. & Krogsgaard, M. R., 1 Feb 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, 1, p. E116-23

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

2014

Differential satellite cell density of type I and II fibres with lifelong endurance running in old men

Mackey, A., Karlsen, A., Couppé, C., Mikkelsen, U. R., Nielsen, R. H., Magnusson, S. P. & Kjaer, M., Mar 2014, In: Acta Physiologica (Print). 210, 3, p. 612-27 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

Whey protein supplementation accelerates satellite cell proliferation during recovery from eccentric exercise

Farup, J., Rahbek, S. K., Knudsen, I. S., de Paoli, F., Mackey, A. & Vissing, K., 26 Jul 2014, In: Amino Acids. 46, 11, p. 2503-2516 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

46 Citations (Scopus)

2013

Ageing is associated with diminished muscle re-growth and myogenic precursor cell expansion early after immobility-induced atrophy in human skeletal muscle

Suetta, C., Frandsen, U., Mackey, A., Jensen, L., Hvid, L. G., Bayer, M. L., Petersson, S. J., Schrøder, H. D., Andersen, J. L., Aagaard, P., Schjerling, P. & Kjaer, M., Aug 2013, In: Journal of Physiology. 591, 15, p. 3789-3804 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

96 Citations (Scopus)

Automated image segmentation of haematoxylin and eosin stained skeletal muscle cross-sections

Liu, F., Mackey, A., Srikuea, R., Esser, K. A. & Yang, L., Dec 2013, In: Journal of Microscopy. 252, 3, p. 275-85 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

Differentially activated macrophages orchestrate myogenic precursor cell fate during human skeletal muscle regeneration

Saclier, M., Yacoub-Youssef, H., Mackey, A., Arnold, L., Ardjoune, H., Magnan, M., Sailhan, F., Chelly, J., Pavlath, G. K., Mounier, R., Kjaer, M. & Chazaud, B., Feb 2013, In: Stem Cells. 31, 2, p. 384-96 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

208 Citations (Scopus)

Does an NSAID a Day Keep Satellite Cells at Bay?

Mackey, A. L., 15 Sept 2013, In: Journal of Applied Physiology. 115, 6, p. 900-908 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Life-long endurance exercise in humans: circulating levels of inflammatory markers and leg muscle size

Mikkelsen, U. R., Couppé, C., Karlsen, A., Grosset, J. F., Schjerling, P., Mackey, A., Klausen, H. H., Magnusson, S. P. & Kjær, M., 1 Dec 2013, In: Mechanisms of Ageing and Development. 134, 11-12, p. 531-40 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

65 Citations (Scopus)

1873 Downloads (Pure)

Morphological adaptation of muscle collagen and receptor of advanced glycation end product (RAGE) in osteoarthritis patients with 12 weeks of resistance training: influence of anti-inflammatory or glucosamine treatment

Mattiello-Sverzut, A. C., Petersen, S. G., Kjaer, M. & Mackey, A., Sept 2013, In: Rheumatology International.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

The expression of HSP in human skeletal muscle. Effects of muscle fiber phenotype and training background

Folkesson, M., Mackey, A. L., Langberg, H., Oskarsson, E., Piehl-Aulin, K., Henriksson, J. & Kadi, F., Sept 2013, In: Acta Physiologica (Print).

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

2012

GH/IGF-I axis and matrix adaptation of the musculotendinous tissue to exercise in humans

Heinemeier, K. M., Mackey, A., Doessing, S., Hansen, M., Bayer, M. L., Nielsen, R. H., Herchenhan, A., Malmgaard-Clausen, N. M. & Kjaer, M., Aug 2012, In: Scandinavian Journal of Medicine & Science in Sports. 22, 4, p. e1-7

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Rehabilitation of muscle after injury - the role of anti-inflammatory drugs

Mackey, A., Mikkelsen, U. R., Magnusson, S. P. & Kjaer, M., Aug 2012, In: Scandinavian Journal of Medicine & Science in Sports. 22, 4, p. e8-14

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

2011

Myogenic response of human skeletal muscle to 12 weeks of resistance training at light loading intensity

Mackey, A., Holm, L., Reitelseder, S., Pedersen, T. G., Doessing, S., Kadi, F. & Kjaer, M., Dec 2011, In: Scandinavian Journal of Medicine & Science in Sports. 21, 6, p. 773-82 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

41 Citations (Scopus)

Nonsteroidal anti-inflammatory drug or glucosamine reduced pain and improved muscle strength with resistance training in a randomized controlled trial of knee osteoarthritis patients

Petersen, S. G., Beyer, N., Hansen, M. R., Holm, L., Aagaard, P., Mackey, A. & Kjaer, M., Aug 2011, In: Archives of Physical Medicine and Rehabilitation. 92, 8, p. 1185-93 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

58 Citations (Scopus)

Nonsteroidal Anti-Inflammatory Drugs; No pain, no gain?

Mackey, A. & Kjær, M., 2011, Best Practice Series, Vol. 1: Recovery and regeneration modalities for Olympic athletes. British Olympic Association, Vol. 1.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

Progressive Resistance Training and Cancer Testis (PROTRACT) - Efficacy of resistance training on muscle function, morphology and inflammatory profile in testicular cancer patients undergoing chemotherapy: design of a randomized controlled trial

Christensen, J. F., Andersen, J. L., Adamsen, L., Lindegaard, B., Mackey, A., Nielsen, R. H., Rørth, M. R. & Daugaard, G., 1 Aug 2011, In: B M C Cancer. 11, 1, 8 p., 326.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Sequenced response of extracellular matrix deadhesion and fibrotic regulators after muscle damage is involved in protection against future injury in human skeletal muscle

Mackey, A., Brandstetter, S., Schjerling, P., Bojsen-Moller, J., Qvortrup, K., Pedersen, M. M., Doessing, S., Kjær, M., Magnusson, S. P. & Langberg, H., Jun 2011, In: FASEB Journal. 25, 6, p. 1943-59 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

111 Citations (Scopus)

Strength training increases the size of the satellite cell pool in type I and II fibres of chronically painful trapezius muscle in females

Mackey, A., Andersen, L. L., Frandsen, U. & Sjøgaard, G., 15 Nov 2011, In: Journal of Physiology. 589, Pt 22, p. 5503-15 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

Structural, biochemical, cellular, and functional changes in skeletal muscle extracellular matrix with aging

Kragstrup, T. W., Kjaer, M. & Mackey, A. L., Dec 2011, In: Scandinavian Journal of Medicine & Science in Sports. 21, 6, p. 749-57 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

110 Citations (Scopus)

2010

Distribution of myogenic progenitor cells and myonuclei is altered in women with vs. those without chronically painful trapezius muscle

Mackey, A., Andersen, L. L., Frandsen, U., Suetta, C. & Sjøgaard, G., 1 Dec 2010, In: Journal of Applied Physiology. 109, 6, p. 1920-9 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

Growth hormone stimulates the collagen synthesis in human tendon and skeletal muscle without affecting myofibrillar protein synthesis

Doessing, S., Heinemeier, K. M., Holm, L., Mackey, A., Schjerling, P., Rennie, M., Petersen, K. S., Reitelseder, S., Kappelgaard, A.-M., Rasmussen, M. H., Flyvbjerg, A. & Kjaer, M., 15 Jan 2010, In: Journal of Physiology. 588, Pt 2, p. 341-51 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

139 Citations (Scopus)

Increased cellular proliferation in rat skeletal muscle and tendon in response to exercise: use of FLT and PET/CT

Skovgaard, D., Bayer, M. L., Mackey, A., Madsen, J., Kjaer, M. & Kjaer, A., Dec 2010, In: Molecular Imaging and Biology. 12, 6, p. 626-34 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Muscle

Kjær, M. & Mackey, A., 2010, Sports Injuries . Oxford University Press

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

Tendon biomechanics

Kjær, M., Magnusson, S. P. & Mackey, A., 2010, Regenerative medicine and biomaterials for the repair of connective tissues. Woodhead Publishing Limited

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

2009

Local NSAID infusion inhibits satellite cell proliferation in human skeletal muscle after eccentric exercise

Mikkelsen, U. R., Langberg, H., Helmark, I. C., Skovgaard, D., Andersen, L. L., Kjaer, M. & Mackey, A., Nov 2009, In: Journal of Applied Physiology. 107, 5, p. 1600-11 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

129 Citations (Scopus)

Abigail Mackey

Research output

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