Lasse Kristoffer Bak

Publikation

Publikationer pr. år 2003 2007 2009 2011 2012 2013 2014 2015 2017 2019 2019

• 59 Tidsskriftartikel
• 7 Bidrag til bog/antologi
• 5 Konferenceabstrakt i tidsskrift
• 5 Review
• 7 Mere
  • 4 Kommentar/debat
  • 2 Poster
  • 1 Letter

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2019

  Aspects of astrocytic cAMP signaling with an emphasis on the putative power of compartmentalized signals in health and disease

  Reuschlein, A-K., Jakobsen, E., Mertz, C. & Bak, L. K., sep. 2019, I: Glia. 67, 9, s. 1625-1636 12 s.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Cyclic AMP 100%
  • Psychological Power 95%
  • Health 49%
  • Astrocytes 37%
  • Drive 20%
  3 Citationer (Scopus)

• PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons

  Bogetofte, H., Jensen, P., Ryding, M., Schmidt, S. I., Okarmus, J., Ritter, L., Worm, C. S., Hohnholt, M. C., Azevedo, C., Roybon, L., Bak, L. K., Waagepetersen, H., Ryan, B. J., Wade-Martins, R., Larsen, M. R. & Meyer, M., 16 jul. 2019, I: Frontiers in Cellular Neuroscience. 13, s. 297

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Neurons 100%
  • Mutation 90%
  • Survival 90%
  • Proteomics 74%
  • parkin protein 69%
  21 Citationer (Scopus)

• Soluble adenylyl cyclase-mediated cAMP signaling and the putative role of PKA and EPAC in cerebral mitochondrial function

  Jakobsen, E., Lange, S. C. & Bak, L. K., aug. 2019, I: Journal of Neuroscience Research. 97, 8, s. 1018-1038 21 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • erythromycin propionate-N-acetylcysteinate 100%
  • Cyclic AMP-Dependent Protein Kinases 56%
  • Adenylyl Cyclases 55%
  • Cyclic AMP 53%
  • Mitochondria 44%
  5 Citationer (Scopus)

  25 Downloads (Pure)

• State-Dependent Changes in Brain Glycogen Metabolism

  DiNuzzo, M., Walls, A. B., Öz, G., Seaquist, E. R., Waagepetersen, H. S., Bak, L. K., Nedergaard, M. & Schousboe, A., 2019, Brain Glycogen Metabolism. DiNuzzo, M. & Schousboe, A. (red.). Springer, s. 269-309 41 s. (Advances in Neurobiology, Bind 23).

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

  • Glycogen 100%
  • Brain 47%
  • Neurophysiology 30%
  • Lenses 22%
  • Homeostasis 17%
  2 Citationer (Scopus)

• Transcriptome analysis in patients with temporal lobe epilepsy

  Kjær, C., Barzaghi, G., Bak, L. K., Goetze, J. P., Yde, C. W., Woldbye, D., Pinborg, L. H. & Jensen, L. J., 1 okt. 2019, I: Brain. 142, 10, s. 49-64 16 s., e55.

  Publikation: Bidrag til tidsskrift › Letter › peer review

  4 Citationer (Scopus)
• 2018

  Astrocytic glycogen metabolism in the healthy and diseased brain

  Bak, L. K., Walls, A. B., Schousboe, A. & Waagepetersen, H. S., 11 maj 2018, I: The Journal of Biological Chemistry. 293, 19, s. 7108-7116 9 s.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Glycogen 100%
  • Brain Diseases 79%
  • Pharmacological Metabolism 64%
  • Astrocytes 23%
  • Brain 20%
  48 Citationer (Scopus)

• CrossTalk opposing view: lack of evidence supporting an astrocyte-to-neuron lactate shuttle coupling neuronal activity to glucose utilisation in the brain

  Bak, L. K. & Walls, A. B., 1 feb. 2018, I: The Journal of Physiology. 596, 3, s. 351-353 3 s.

  Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review

  37 Citationer (Scopus)

  31 Downloads (Pure)

• Rebuttal from Lasse K. Bak and Anne B. Walls

  Bak, L. K. & Walls, A. B., 1 feb. 2018, I: The Journal of Physiology. 596, 3, s. 357

  Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review

  1 Citationer (Scopus)

  28 Downloads (Pure)

• The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms

  Jakobsen, E., Lange, S. C., Andersen, J. V., Madsen, C. D., Kihl, H. F., Hohnholt, M., Stridh, M. H., Rasmussen, L. J., Waagepetersen, H. S. & Bak, L. K., sep. 2018, I: Biochemical Pharmacology. 155, s. 92-101 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Bithionol 100%
  • Adenylyl Cyclase Inhibitors 77%
  • Adenylyl Cyclases 52%
  • Adenosine Triphosphate 40%
  • Pharmacological Metabolism 26%
  10 Citationer (Scopus)
• 2017

  Astrocytes take the stage in a tale of signaling-metabolism coupling

  Bak, L. K., 2 jun. 2017, I: The Journal of Biological Chemistry. 292, 22, s. 9439-9440 2 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Lactate 100%
  • Astrocytes 90%
  • Lactic Acid 88%
  • Pharmacological Metabolism 50%
  • Brain 32%
  2 Citationer (Scopus)

  71 Downloads (Pure)

• Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons

  Aldana, B. I., Zhang, Y., Lihme, M. F., Bak, L. K., Nielsen, J. E., Holst, B., Hyttel, P., Freude, K. K. & Waagepetersen, H. S., jun. 2017, I: Neurochemistry International. 106, s. 48-61

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Induced Pluripotent Stem Cells 100%
  • Energy Metabolism 80%
  • Neurotransmitter Agents 77%
  • Neurons 54%
  • Glutamine 19%
  11 Citationer (Scopus)

  45 Downloads (Pure)

• Compartmentalised signalling-metabolism coupling in brain cells - putative drug targets for neurological diseases?

  Bak, L., Reuschlein, A. -K., Kjaer, C., Jakobsen, E., Hedehus, J., Mertz, C., Madsen, S., Jensen, M., Bergstedt, N., Knezevic, A. & Lindholm, S., aug. 2017, I: Journal of Neurochemistry. 142, S1, s. 145-145

  Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning › peer review

  166 Downloads (Pure)

• Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes

  Nissen, J. D., Lykke, K., Bryk, J., Stridh, M. H., Zaganas, I., Skytt, D. M., Schousboe, A., Bak, L. K., Enard, W., Pääbo, S. & Waagepetersen, H. S., 1 mar. 2017, I: Glia. 65, 3, s. 474–488

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glutamate Dehydrogenase 100%
  • Citric Acid Cycle 89%
  • Astrocytes 66%
  • Glutamic Acid 63%
  • Protein Isoforms 58%
  21 Citationer (Scopus)

• Glucose, Lactate and Glutamine but not Glutamate Support Depolarization-Induced Increased Respiration in Isolated Nerve Terminals

  Hohnholt, M. C., Andersen, V. H., Bak, L. K. & Waagepetersen, H. S., 1 jan. 2017, I: Neurochemical Research. 42, 1, s. 191-201 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glutamine 100%
  • Lactate 91%
  • Lactic Acid 80%
  • Glutamic Acid 79%
  • Respiration 75%
  7 Citationer (Scopus)

• Glycogen Shunt Activity and Glycolytic Supercompensation in Astrocytes May Be Distinctly Mediated via the Muscle Form of Glycogen Phosphorylase

  Jakobsen, E., Bak, L. K., Walls, A. B., Reuschlein, A-K., Schousboe, A. & Waagepetersen, H. S., 1 sep. 2017, I: Neurochemical Research. 42, 9, s. 2490-2494 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Muscle Form Glycogen Phosphorylase 100%
  • Glycogen 64%
  • Astrocytes 49%
  • Protein Isoforms 28%
  • Glycogen Phosphorylase 25%
  7 Citationer (Scopus)

• Inhibition of soluble adenylyl cyclase (SAC) causes a robust increase in glycolysis in cultured astrocytes

  Jakobsen, E., Madsen, S. F., Hedehus, J., Rubio-Villena, C., Jorgensen, N. H. & Bak, L. K., aug. 2017, s. 147-147.

  Publikation: Konferencebidrag › Poster › Forskning

  86 Downloads (Pure)

• Misconceptions regarding basic thermodynamics and enzyme kinetics have led to erroneous conclusions regarding the metabolic importance of lactate dehydrogenase isoenzyme expression

  Bak, L. K. & Schousboe, A., nov. 2017, I: Journal of Neuroscience Research. 95, 11, s. 2098-2102 5 s.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Thermodynamics 100%
  • L-Lactate Dehydrogenase 82%
  • Isoenzymes 82%
  • Lactic Acid 73%
  • Kinetics 59%
  14 Citationer (Scopus)

• Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B

  Zhang, Y., Schmid, B., Nikolaisen, N. K., Rasmussen, M. A., Garcia, B. I. A., Agger, M., Callø, K., Stummann, T. C., Larsen, H. M., Nielsen, T. T., Huang, J., Xu, F., Liu, X., Bolund, L., Meyer, M., Bak, L. K., Waagepetersen, H. S., Luo, Y., Nielsen, J. E., Consortium, T. FRA., & 4 flereHolst, B., Clausen, C., Hyttel, P. & Freude, K., 14 mar. 2017, I: Stem Cell Reports. 8, 3, s. 648-658

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Multivesicular Bodies 100%
  • Frontotemporal Dementia 89%
  • Induced Pluripotent Stem Cells 81%
  • Mutation 60%
  • Neurons 44%
  34 Citationer (Scopus)

  471 Downloads (Pure)
• 2016

  Neuronal Cell Death Induced by Mechanical Percussion Trauma in Cultured Neurons is not Preceded by Alterations in Glucose, Lactate and Glutamine Metabolism

  Jayakumar, A. R., Bak, L. K., Rama Rao, K. V., Waagepetersen, H. S., Schousboe, A. & Norenberg, M. D., 4 jan. 2016, I: Neurochemical Research. 41, 1, s. 307-15 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Percussion 100%
  • Glutamine 81%
  • Cell Death 78%
  • Lactate 74%
  • Lactic Acid 65%
  6 Citationer (Scopus)

• The anticonvulsant action of the galanin receptor agonist NAX-5055 involves modulation of both excitatory- and inhibitory neurotransmission

  Walls, A. B., Flynn, S. P., West, P. J., Müller, M. S., Bak, L. K., Bulaj, G., Schousboe, A. & White, H. S., 1 mar. 2016, I: Epilepsy Research. 121, s. 55-63 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • NAX 5055 100%
  • Galanin Receptors 70%
  • Galanin 42%
  • Anticonvulsants 41%
  • Synaptic Transmission 41%
  5 Citationer (Scopus)
• 2015

  Dynamic changes in cytosolic ATP levels in cultured glutamatergic neurons during NMDA-induced synaptic activity supported by glucose or lactate

  Lange, S. C., Winkler, U., Andresen, L., Byhrø, M., Waagepetersen, H. S., Hirrlinger, J. & Bak, L. K., 1 dec. 2015, I: Neurochemical Research. 40, 12, s. 2517-2526 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • N-Methylaspartate 100%
  • Lactate 93%
  • Lactic Acid 82%
  • Adenosine Triphosphate 71%
  • Glucose 67%
  8 Citationer (Scopus)

• Fluctuations in Cytosolic Calcium Regulate the Neuronal Malate-Aspartate NADH Shuttle: Implications for Neuronal Energy Metabolism

  Satrústegui, J. & Bak, L. K., 1 dec. 2015, I: Neurochemical Research. 40, 12, s. 2425-30 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • malic acid 100%
  • Aspartic Acid 78%
  • NAD 77%
  • Lactate 76%
  • Energy Metabolism 68%
  14 Citationer (Scopus)

• Glutamine and ammonia in hepatic encephalopathy

  Dadsetan, S., Waagepetersen, H. S., Schousboe, A. & Bak, L. K., 1 jan. 2015, Glutamine in Clinical Nutrition. Springer New York LLC, s. 219-227 9 s.

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

  • Hepatic Encephalopathy 100%
  • Ammonia 94%
  • Glutamine 87%
  • Disorders of Excessive Somnolence 39%
  • Apathy 35%
  3 Citationer (Scopus)

• Isoform-selective regulation of glycogen phosphorylase by energy deprivation and phosphorylation in astrocytes

  Müller, M. S., Pedersen, S. E., Walls, A. B., Waagepetersen, H. S. & Bak, L. K., 1 jan. 2015, I: Glia. 63, 1, s. 154-62 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glycogen Phosphorylase 100%
  • Astrocytes 65%
  • Protein Isoforms 57%
  • Phosphorylation 48%
  • Glycogen 36%
  28 Citationer (Scopus)

• Two isoforms of glycogen phosphorylase activated by the same signaling trains: how and why?

  Bak, L., Mueller, M. S., Fox, R., Pedersen, S. E., Walls, A. B., Reuschlein, A. -K., Jakobsen, E., Schousboe, A. & Waagepetersen, H. S., aug. 2015, I: Journal of Neurochemistry. 134, suppl. 1, s. 56-56 1 s., S26-01.

  Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning › peer review

  7 Citationer (Scopus)
• 2014

  Astrocyte glycogenolysis is triggered by store-operated calcium entry and provides metabolic energy for cellular calcium homeostasis

  Müller, M. S., Fox, R., Schousboe, A., Waagepetersen, H. S. & Bak, L. K., apr. 2014, I: Glia. 62, 4, s. 526-34 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glycogenolysis 100%
  • Glycogen 76%
  • Astrocytes 67%
  • Homeostasis 53%
  • Calcium 50%
  44 Citationer (Scopus)

• Effect of glutamine synthetase inhibition on brain and interorgan ammonia metabolism in bile duct ligated rats

  Fries, A. W., Dadsetan, S., Keiding, S., Bak, L. K., Schousboe, A., Waagepetersen, H. S., Simonsen, M., Ott, P., Vilstrup, H. & Sørensen, M., mar. 2014, I: Journal of Cerebral Blood Flow and Metabolism. 34, 3, s. 460-6 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glutamate-Ammonia Ligase 100%
  • Ammonia 84%
  • Bile Ducts 75%
  • Methionine Sulfoximine 69%
  • Alanine 64%
  13 Citationer (Scopus)

• Effects of hyperammonemia on brain energy metabolism: controversial findings in vivo and in vitro

  Schousboe, A., Waagepetersen, H. S., Leke, R. & Bak, L. K., 13 nov. 2014, I: Metabolic Brain Disease. 29, 4, s. 913-917 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hyperammonemia 100%
  • Ammonia 83%
  • Energy Metabolism 66%
  • Hepatic Encephalopathy 58%
  • Pharmacological Metabolism 57%
  13 Citationer (Scopus)

• Glutamate dehydrogenase Isoforms with N-Terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization

  Pajecka, K., Nielsen, C. W., Hauge, A., Zaganas, I., Bak, L. K., Schousboe, A., Plaitakis, A. & Waagepetersen, H. S., mar. 2014, I: Neurochemical Research. 39, 3, s. 487-499

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • His-His-His-His-His-His 100%
  • Glutamate Dehydrogenase 97%
  • Protein Isoforms 57%
  • Kinetics 51%
  • Adenosine Diphosphate 46%
  5 Citationer (Scopus)

• Glutamate dehydrogenase isoforms with N-terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization

  Pajęcka, K., Nielsen, C. W., Hauge, A., Zaganas, I., Bak, L. K., Schousboe, A., Plaitakis, A. & Waagepetersen, H. S., mar. 2014, I: Neurochemical Research. 39, 3, s. 487-99 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • His-His-His-His-His-His 100%
  • Glutamate Dehydrogenase 97%
  • Protein Isoforms 57%
  • Kinetics 51%
  • Adenosine Diphosphate 46%
  5 Citationer (Scopus)

• Glutamate metabolism in the brain focusing on astrocytes

  Schousboe, A., Scafidi, S., Bak, L. K., Waagepetersen, H. S. & McKenna, M. C., 2014, I: Advances in Neurobiology. 11, s. 13-30 18 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glutamine 100%
  • Astrocytes 83%
  • Glutamic Acid 79%
  • Pharmacological Metabolism 70%
  • Neurotransmitter 67%

• Metabolic mapping of astrocytes and neurons in culture using stable isotopes and gas chromatography-mass spectrometry (GC-MS)

  Walls, A. B., Bak, L. K., Sonnewald, U., Schousboe, A. & Waagepetersen, H. S., 1 jan. 2014, I: Neuromethods. 90, s. 73-105 33 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Gas Chromatography-Mass Spectrometry 100%
  • Stable Isotope 92%
  • Isotopes 91%
  • Astrocytes 78%
  • Metabolic 69%
  31 Citationer (Scopus)

• Oxidative metabolism of astrocytes is not reduced in hepatic encephalopathy: a PET study with [(11)C]acetate in humans

  Iversen, P., Mouridsen, K., Hansen, M. B., Jensen, S. B., Sørensen, M., Bak, L. K., Waagepetersen, H. S., Schousboe, A., Ott, P., Vilstrup, H., Keiding, S. & Gjedde, A., 2014, I: Frontiers in Neuroscience. 8, s. 353

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepatic Encephalopathy 100%
  • carbon-11 acetate 99%
  • Acetates 82%
  • Astrocytes 76%
  • Brain 29%
  9 Citationer (Scopus)

  37 Downloads (Pure)

• The Glutamine-Glutamate/GABA Cycle: Function, Regional Differences in Glutamate and GABA Production and Effects of Interference with GABA Metabolism

  Walls, A. B., Waagepetersen, H. S., Bak, L. K., Schousboe, A. & Sonnewald, U., feb. 2014, I: Neurochemical Research. 40, 2, s. 402-9 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • GABA Agents 100%
  • Glutamine 71%
  • gamma-Aminobutyric Acid 62%
  • Glutamic Acid 56%
  • Pharmacological Metabolism 50%
  76 Citationer (Scopus)
• 2013

  Amino acid neurotransmitter synthesis and removal

  Schousboe, A., Bak, L. K., Madsen, K. K. & Waagepetersen, H. S., 2013, Neuroglia. Kettenman, H. & Ransom, B. R. (red.). 3. udg. Oxford: Oxford University Press, s. 443-456 14 s.

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

• Astrocytic control of biosynthesis and turnover of the neurotransmitters glutamate and GABA

  Schousboe, A., Bak, L. K. & Waagepetersen, H. S., 15 aug. 2013, I: Frontiers in Endocrinology. 4, 102.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • gamma-Aminobutyric Acid 100%
  • Glutamic Acid 91%
  • Neurotransmitter Agents 91%
  • Astrocytes 76%
  • Amino Acids 58%
  154 Citationer (Scopus)

• Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia: effects of glutamine synthetase inhibition in rats and astrocyte-neuron co-cultures

  Dadsetan, S., Kukolj, E., Bak, L. K., Sørensen, M., Ott, P., Vilstrup, H., Schousboe, A., Keiding, S. & Waagepetersen, H. S., aug. 2013, I: Journal of Cerebral Blood Flow and Metabolism. 33, 8, s. 1235-41 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Methionine Sulfoximine 100%
  • Hyperammonemia 82%
  • Glutamate-Ammonia Ligase 81%
  • Ammonia 68%
  • Alanine 61%
  22 Citationer (Scopus)

• Complex actions of ionomycin in cultured cerebellar astrocytes affecting both calcium-induced calcium release and store-operated calcium entry

  Müller, M. S., Obel, L. L. F., Waagepetersen, H. S., Schousboe, A. & Bak, L. K., jun. 2013, I: Neurochemical Research. 38, 6, s. 1260-5 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Ionomycin 100%
  • Astrocytes 58%
  • Calcium(0) 48%
  • Calcium 43%
  • Cytosol 24%
  14 Citationer (Scopus)

• Hepatic encephalopathy is associated with decreased cerebral oxygen metabolism and blood flow, not increased ammonia uptake

  Dam, G., Keiding, S., Munk, O. L., Ott, P., Vilstrup, H., Bak, L. K., Waagepetersen, H. S., Schousboe, A. & Sørensen, M., jan. 2013, I: Hepatology. 57, 1, s. 258-65 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepatic Encephalopathy 100%
  • Ammonia 94%
  • Oxygen 59%
  • Fibrosis 34%
  • Positron Emission Tomography Computed Tomography 10%
  47 Citationer (Scopus)

• Interorgan metabolism of ornithine phenylacetate (OP)-A novel strategy for treatment of hyperammonemia

  Dadsetan, S., Sørensen, M., Bak, L. K., Vilstrup, H., Ott, P., Schousboe, A., Jalan, R., Keiding, S. & Waagepetersen, H. S., 1 jan. 2013, I: Biochemical Pharmacology. 85, 1, s. 115-23 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • ornithine phenylacetate 100%
  • Hyperammonemia 64%
  • Phenylacetate 62%
  • Ornithine 59%
  • Pharmacological Metabolism 36%
  12 Citationer (Scopus)

• Reply to letter to the editor by Zheng G et al. Venous blood ammonia can be associated with cerebral blood flow in hepatic encephalopathy

  Dam, G., Keiding, S., Munk, O. L., Ott, P., Vilstrup, H., Bak, L. K., Waagepetersen, H. S., Schousboe, A. & Sørensen, M., 2013, I: Hepatology. 58, 2, s. 833-834

  Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review

  1 Citationer (Scopus)

• Role of branched chain amino acids in cerebral ammonia homeostasis related to hepatic encephalopathy

  Bak, L. K., Waagepetersen, H. S., Sørensen, M., Ott, P., Vilstrup, H., Keiding, S. & Schousboe, A., jun. 2013, I: Metabolic Brain Disease. 28, 2, s. 209-15 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Branched-Chain Amino Acid 100%
  • Branched Chain Amino Acids 90%
  • Hepatic Encephalopathy 83%
  • Ammonia 78%
  • Isoleucine 65%
  15 Citationer (Scopus)
• 2012

  Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation

  Kreft, M., Bak, L. K., Waagepetersen, H. S. & Schousboe, A., 2012, I: A S N Neuro. 4, 3, s. 187 199 s.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Astrocytes 100%
  • Energy Metabolism 98%
  • Neurotransmitter Agents 95%
  • Homeostasis 79%
  • Amino Acids 76%
  63 Citationer (Scopus)

• Brain energy and ammonia metabolism

  Bak, L. K., Schousboe, A. & Waagepetersen, H. S., 2012, Functional molecular imaging in hepatology. Bentham Science Publishers, Bind 1. s. 129-144 16 s.

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

• Brain glycogen: new perspectives on its metabolic function and regulation at the subcellular level

  Obel, L. L. F., Müller, M. S., Walls, A. B., Sickmann, H. M., Bak, L. K., Waagepetersen, H. S. & Schousboe, A., 2 mar. 2012, I: Frontiers in Neuroenergetics. 4, 15 s.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Glycogen 100%
  • Brain 47%
  • Astrocytes 16%
  • Glucans 11%
  • Second Messenger Systems 9%
  121 Citationer (Scopus)

• Effects of adrenergic agents on intracellular ca(2+) homeostasis and metabolism of glucose in astrocytes with an emphasis on pyruvate carboxylation, oxidative decarboxylation and recycling: implications for glutamate neurotransmission and excitotoxicity

  Obel, L. L. F., Andersen, K. M. H., Bak, L. K., Schousboe, A. & Waagepetersen, H. S., maj 2012, I: Neurotoxicity Research. 21, 4, s. 405-17 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Adrenergic Agent 100%
  • Excitotoxicity 99%
  • Decarboxylation 79%
  • Oxidative Decarboxylation 77%
  • Carboxylation 69%
  18 Citationer (Scopus)

• Impairment of the organization of locomotor and exploratory behaviors in bile duct-ligated rats

  Leke, R., de Oliveira, D. L., Mussulini, B. H. M., Pereira, M. S., Kazlauckas, V., Mazzini, G., Hartmann, C. R., Silveira, T. R., Simonsen, M., Bak, L. K., Waagepetersen, H. S., Keiding, S., Schousboe, A. & Portela, L. V., 7 maj 2012, I: P L o S One. 7, 5, s. e36322

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • bile ducts 100%
  • Exploratory Behavior 99%
  • Rats 93%
  • Bile Ducts 81%
  • Ducts 78%
  26 Citationer (Scopus)

• Novel model of neuronal bioenergetics: postsynaptic utilization of glucose but not lactate correlates positively with Ca²⁺ signalling in cultured mouse glutamatergic neurons

  Bak, L. K., Obel, L. L. F., Walls, A. B., Schousboe, A., Faek, S. A. A., Jajo, F. S. & Waagepetersen, H. S., 2012, I: A S N Neuro. 4, 3, s. 151-160

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Energy Metabolism 100%
  • Lactic Acid 98%
  • Glucose 69%
  • Neurons 68%
  • Aspartic Acid 31%
  33 Citationer (Scopus)

• Primary cultures of astrocytes: their value in understanding astrocytes in health and disease

  Lange, S. C., Bak, L. K., Waagepetersen, H. S., Schousboe, A. & Norenberg, M. D., nov. 2012, I: Neurochemical Research. 37, 11, s. 2569-88 20 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Astrocytes 100%
  • Pharmacological Metabolism 83%
  • Calcium(0) 83%
  • Health 52%
  • Acid 37%
  94 Citationer (Scopus)

• Valine but not leucine or isoleucine supports neurotransmitter glutamate synthesis during synaptic activity in cultured cerebellar neurons

  Bak, L. K., Johansen, M. L., Schousboe, A. & Waagepetersen, H. S., sep. 2012, I: Journal of Neuroscience Research. 90, 9, s. 1768-75 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Isoleucine 100%
  • Valine 94%
  • Leucine 81%
  • Glutamic Acid 70%
  • Neurotransmitter Agents 69%
  10 Citationer (Scopus)