Publikationer pr. år
Publikationer pr. år
Personlig profil
Kort præsentation
My current research interests are induced pluipotent cells (iPSC) from pigs and humans.
Regarding the porcine iPSC I am working on making naive pluripotent stem cells which are able to generate chimeras. Furthermore, I am comparing the pluripotent state of porcine iPSC to porcine embryos via RNAseq to understand similarities and discrepancies in regards to pluripotency.
I am interested in neurodegenerative disorder in particular Alzheimer's disease and frontotemporal dementia. I am using patient specific iPSC and differentiate these into disease relevant neuronal subtypes to investigate the underlying disaese mechanisms.
Emneord
- Det Natur- og Biovidenskabelige Fakultet
Fingeraftryk
Dyk ned i forskningsemnerne, hvor Kristine Freude er aktive. Disse emneetiketter kommer fra dennes persons arbejder. Sammen danner de et unikt fingerprint.
- 11 Lignende profiler
Publikation
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Cell type specific expression of toll-like receptors in human brains and implications in Alzheimer's disease
Frederiksen, H. R., Haukedal, H. & Freude, K., 2019, I: BioMed Research International. 2019, 18 s., 7420189.Publikation: Bidrag til tidsskrift › Review › peer review
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Dementia, Brain Disorders and Molecular Mechanisms
Freude, K. & Krauss, S., 19 apr. 2019, I: Journal of Molecular Biology. 431, 9, s. 1709-1710Publikation: Bidrag til tidsskrift › Leder
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Generation of two iPSC lines with either a heterozygous V717I or a heterozygous KM670/671NL mutation in the APP gene
Frederiksen, H. R., Holst, B., Ramakrishna, S., Muddashetty, R., Schmid, B. & Freude, K., 1 jan. 2019, I: Stem Cell Research. 34, 5 s., 101368.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Generation of two isogenic iPSC lines with either a heterozygous or a homozygous E280A mutation in the PSEN1 gene.
Frederiksen, H. R. S., Holst, B., Mau-Holzmann, U. A., Freude, K. & Schmid, B., mar. 2019, I: Stem Cell Research. 35, 4 s., 101403.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Implications of Microglia in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Haukedal, H. & Freude, K., 19 apr. 2019, I: Journal of Molecular Biology. 431, 9, s. 1818-1829Publikation: Bidrag til tidsskrift › Review › peer review
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Induced pluripotent stem cells throughout the animal kingdom: Availability and applications
Pessôa, L. V. D. F., Bressan, F. F. & Freude, K. K., 2019, I: World Journal of Stem Cells. 11, 8, s. 491-505 15 s.Publikation: Bidrag til tidsskrift › Review › peer review
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Modelling the neuropathology of lysosomal storage disorders through disease-specific human induced pluripotent stem cells
Kobolák, J., Molnár, K., Varga, E., Bock, I., Jezsó, B., Téglási, A., Zhou, S., Lo Giudice, M., Hoogeveen-Westerveld, M., Pijnappel, W. P., Phanthong, P., Varga, N., Kitiyanant, N., Freude, K., Nakanishi, H., László, L., Hyttel, P. & Dinnyés, A., 2019, I: Experimental Cell Research. 380, 2, s. 216-233 18 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Oocytes, embryos and pluripotent stem cells from a biomedical perspective
Hyttel, P., Pessôa, L. V. D. F., Secher, J. B. M., Dittlau, K. S., Freude, K., Hall, V. J., Fair, T., Assey, R. J., Laurincik, J., Callesen, H., Greve, T. & Stroebech, L. B., 2019, I: Animal Reproduction. 16, 3, s. 508-523 16 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review