Publikationer pr. år
Publikationer pr. år
Personlig profil
Kort præsentation
My current research interest is focused on establishing in vitro neuronal and glial cell models of neurodegenerative disorders from patient-specific induced pluripotent stem cells (iPS Cells), including generation of isogenic controls using CRISPR-Cas9 genome editing system to correct the inherited mutation, furthermore, identifying novel disease mechanisms as well as pharmaceutical targets through integrative high-throughput omics profiling and microscopic imaging.
Uddannelse (Akademiske kvalifikationer)
Generation and characterization of porcine induced pluripotent stem cells reprogrammed from adipose-derived stem cells, Anhui Agricultural University
sep. 2010 → jun. 2013
Dimissionsdato: 1 jul. 2008
Modeling and study of frontotemporal dementia using genetically engineered human iPS cells, University of Copenhagen
jan. 2014 → …
Eksterne ansættelser
Department of Drug Design and Pharmacology, KU
jan. 2017 → …
Emneord
- Det Sundhedsvidenskabelige Fakultet
Fingeraftryk
Dyk ned i forskningsemnerne, hvor Yu Zhang er aktive. Disse emneetiketter kommer fra dennes persons arbejder. Sammen danner de et unikt fingerprint.
- 6 Lignende profiler
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Identification of the Gene Expression Rules That Define the Subtypes in Glioma
Cai, Y-D., Zhang, S., Zhang, Y-H., Pan, X., Feng, K., Chen, L., Huang, T. & Kong, X., okt. 2018, I: Journal of Clinical Medicine. 7, 10, 15 s., 350.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons
Aldana, B. I., Zhang, Y., Lihme, M. F., Bak, L. K., Nielsen, J. E., Holst, B., Hyttel, P., Freude, K. K. & Waagepetersen, H. S., jun. 2017, I: Neurochemistry International. 106, s. 48-61Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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DOT1L inhibitor improves early development of porcine somatic cell nuclear transfer embryos
Tao, J., Zhang, Y., Zuo, X., Hong, R., Li, H., Liu, X., Huang, W., Cao, Z. & Zhang, Y., jun. 2017, I: PloS one. 12, 6, 12 s., e0179436.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges
Poon, A., Zhang, Y., Chandrasekaran, A., Phanthong, P., Schmid, B., Nielsen, T. T. & Freude, K. K., 25 okt. 2017, I: New Biotechnology. 39, Part B, s. 190-198Publikation: Bidrag til tidsskrift › Review › peer review
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Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B
Zhang, Y., Schmid, B., Nikolaisen, N. K., Rasmussen, M. A., Garcia, B. I. A., Agger, M., Callø, K., Stummann, T. C., Larsen, H. M., Nielsen, T. T., Huang, J., Xu, F., Liu, X., Bolund, L., Meyer, M., Bak, L. K., Waagepetersen, H. S., Luo, Y., Nielsen, J. E., Consortium, T. FRA., & 4 flere, 14 mar. 2017, I: Stem Cell Reports. 8, 3, s. 648-658Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific heterozygous mutation in CHMP2B
Zhang, Y., Schmid, B., Nielsen, T. T., Nielsen, J. E., Clausen, C., Hyttel, P., Holst, B. & Freude, K., jul. 2016, I: Stem Cell Research. 17, 1, s. 148-150 3 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific homozygous mutation in CHMP2B
Zhang, Y., Schmid, B., Nielsen, T. T., Nielsen, J. E., Clausen, C., Hyttel, P., Holst, B. & Freude, K. K., 2016, I: Stem Cell Research. 17, 1, s. 151-153 3 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Characterization of porcine partially reprogrammed iPSCs from adipose-derived stem cells
Wei, C., Li, X., Zhang, P., Zhang, Y., Liu, T., Jiang, S., Han, F. & Zhang, Y., 1 maj 2015, I: Reproduction. 149, 5, s. 485-496 12 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review