Henrik Clausen

Publikation

Publikationer pr. år 1986 1997 1998 1999 2000 2006 2007 2010 2011 2012 2013 2014 2015 2017 2018 2019 2019

• 235 Tidsskriftartikel
• 9 Bidrag til bog/antologi
• 7 Review
• 5 Konferenceabstrakt i tidsskrift
• 4 Mere
  • 2 Kommentar/debat
  • 1 Letter
  • 1 Andet bidrag

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2019

  A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion

  Valoskova, K., Biebl, J., Roblek, M., Emtenani, S., Gyoergy, A., Misova, M., Ratheesh, A., Reis-Rodrigues, P., Shkarina, K., Larsen, I. S. B., Vakhrushev, S. Y., Clausen, H. & Siekhaus, D. E., mar. 2019, I: eLife. 8, 41 s., e41801.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Viral Tumor Antigens 100%
  • Glycosylation 84%
  • O-Glycan 59%
  • Macrophages 57%
  • Drosophila melanogaster 35%
  6 Citationer (Scopus)

  45 Downloads (Pure)

• Activity of N-acylneuraminate-9-phosphatase (NANP) is not essential for de novo sialic acid biosynthesis

  Willems, A. P., Sun, L., Schulz, M. A., Tian, W., Ashikov, A., van Scherpenzeel, M., Hermans, E., Clausen, H., Yang, Z. & Lefeber, D. J., 2019, I: Biochimica et Biophysica Acta - General Subjects. 1863, 10, s. 1471-1479 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • N-acylneuraminate-9-phosphatase 100%
  • N-Acetylneuraminic Acid 46%
  • Sialic Acid 44%
  • Biosynthesis 33%
  • Cytidine Monophosphate N-Acetylneuraminic Acid 19%
  5 Citationer (Scopus)

• An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells

  Narimatsu, Y., Joshi, H. J., Nason, R., Van Coillie, J., Karlsson, R., Sun, L., Ye, Z., Chen, Y-H., Schjoldager, K. T., Steentoft, C., Furukawa, S., Bensing, B. A., Sullam, P. M., Thompson, A. J., Paulson, J. C., Büll, C., Adema, G. J., Mandel, U., Hansen, L., Bennett, E. P., & 4 flereVarki, A., Vakhrushev, S. Y., Yang, Z. & Clausen, H., 25 jul. 2019, I: Molecular Cell. 75, 2, s. 394-407, e1-e5

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Atlases 100%
  • Glycosylation 95%
  • Polysaccharides 87%
  • Genes 37%
  • Glycosyltransferases 12%
  50 Citationer (Scopus)

• Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor

  Hansen, L. H., Madsen, T. D., Goth, C. K., Clausen, H., Chen, Y., Dzhoyashvili, N., Iyer, S. R., Sangaralingham, S. J., Burnett, J. C., Rehfeld, J. F., Vakhrushev, S. Y., Schjoldager, K. T. & Goetze, J. P., 23 aug. 2019, I: Journal of Biological Chemistry. 294, 34, s. 12567-12578 12 s.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Atrial Natriuretic Peptide 100%
  • O-Glycan 91%
  • Atrial Natriuretic Factor 69%
  • Polysaccharides 59%
  • Glycosylation 27%
  17 Citationer (Scopus)

• Erratum: Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions (Journal of Biological Chemistry (2018) 293 (7408-7422) DOI: 10.1074/jbc.M117.817981)

  Wang, S., Mao, Y., Narimatsu, Y., Ye, Z., Tian, W., Goth, C. K., Lira-Navarrete, E., Pedersen, N. B., Benito-Vicente, A., Martin, C., Uribe, K. B., Hurtado-Guerrero, R., Christoffersen, C., Seidah, N. G., Nielsen, R., Christensen, E. I., Hansen, L., Bennett, E. P., Vakhrushev, S. Y., Schjoldager, K. T., & 1 flereClausen, H., 24 maj 2019, I: Journal of Biological Chemistry. 294, 21, 1 s.

  Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review

  • Low-Density Lipoprotein 100%
  • LDL Receptors 99%
  • Glycosylation 88%
  • oxidized low density lipoprotein 86%
  • Ligands 60%
  2 Citationer (Scopus)

• Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics

  Narimatsu, Y., Joshi, H. J., Schjoldager, K. T., Hintze, J., Halim, A., Steentoft, C., Nason, R., Mandel, U., Bennett, E. P., Clausen, H. & Vakhrushev, S. Y., 2019, I: Molecular and Cellular Proteomics. 18, 7, s. 1396-1409

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • HEK293 Cells 100%
  • Glycosylation 94%
  • polypeptide N-acetylgalactosaminyltransferase 92%
  • Protein Isoforms 74%
  • O-Glycan 67%
  16 Citationer (Scopus)

• Glyco-DIA: a method for quantitative O-glycoproteomics with in silico-boosted glycopeptide libraries

  Ye, Z., Mao, Y., Clausen, H. & Vakhrushev, S. Y., 1 sep. 2019, I: Nature Methods. 16, 9, s. 902-910 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glycopeptides 100%
  • Glycopeptide 89%
  • O-Glycan 86%
  • Computer Simulation 74%
  • O-Glycoprotein 71%
  24 Citationer (Scopus)

• Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell

  He, Y., Schreiber, K., Wolf, S. P., Wen, F., Steentoft, C., Zerweck, J., Steiner, M., Sharma, P., Shepard, H. M., Posey, A., June, C. H., Mandel, U., Clausen, H., Leisegang, M., Meredith, S. C., Kranz, D. M. & Schreiber, H., 17 okt. 2019, I: JCI insight. 4, 21

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Chimeric Antigen Receptors 100%
  • Antigens 47%
  • Neoplasms 23%
  • Tn antigen 20%
  • Tumor Escape 16%
  9 Citationer (Scopus)

• Multiple distinct O-Mannosylation pathways in eukaryotes

  Larsen, I. S. B., Narimatsu, Y., Clausen, H., Joshi, H. J. & Halim, A., jun. 2019, I: Current Opinion in Structural Biology. 56, s. 171-178 8 s.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Eukaryota 100%
  • Glycosylation 99%
  • Yeasts 65%
  • plexin 50%
  • Post Translational Protein Processing 33%
  9 Citationer (Scopus)

• Targeted analysis of lysosomal directed proteins and their sites of mannose-6-phosphate modification

  Caval, T., Zhu, J., Tian, W., Remmelzwaal, S., Yang, Z., Clausen, H. & Heck, A. J. R., 2019, I: Molecular and Cellular Proteomics. 18, 1, s. 16-27 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Mannose 6-Phosphate 100%
  • mannose-6-phosphate 98%
  • lysosomal proteins 95%
  • Modification 36%
  • Glycoprotein 35%
  17 Citationer (Scopus)

• The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells

  Tian, W., Ye, Z., Wang, S., Schulz, M. A., Van Coillie, J., Sun, L., Chen, Y-H., Narimatsu, Y., Hansen, L., Kristensen, C., Mandel, U., Bennett, E. P., Jabbarzadeh-Tabrizi, S., Schiffmann, R., Shen, J-S., Vakhrushev, S. Y., Clausen, H. & Yang, Z., 1 dec. 2019, I: Nature Communications. 10, 13 s., 1785.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • CHO Cells 100%
  • enzymes 88%
  • Glycosylation 85%
  • Polysaccharides 65%
  • Enzymes 45%
  21 Citationer (Scopus)

  10 Downloads (Pure)

• Towards universally acceptable blood

  Clausen, H. & Olsson, M. L., 1 sep. 2019, I: Nature Microbiology. 4, 9, s. 1426-1427 2 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  1 Citationer (Scopus)
• 2018

  A validated gRNA library for CRISPR/Cas9 targeting of the human glycosyltransferase genome

  Narimatsu, Y., Joshi, H. J., Zhang, Y., Gomes, C., Chen, Y-H., Lorenzetti, F., Furukawa, S., Schjoldager, K., Hansen, L., Clausen, H., Bennett, E. P. & Wandall, H. H., 1 maj 2018, I: Glycobiology. 28, 5, s. 295–305

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Guide RNA 100%
  • Glycosyltransferases 96%
  • Clustered Regularly Interspaced Short Palindromic Repeats 82%
  • Human Genome 75%
  • Polysaccharides 67%
  29 Citationer (Scopus)

• Current Technologies for Complex Glycoproteomics and Their Applications to Biology/Disease-Driven Glycoproteomics

  Narimatsu, H., Kaji, H., Vakhrushev, S. Y., Clausen, H., Zhang, H., Noro, E., Togayachi, A., Nagai-Okatani, C., Kuno, A., Zou, X., Cheng, L., Tao, S-C. & Sun, Y., 7 dec. 2018, I: Journal of Proteome Research. 17, 12, s. 4097–4112

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Glycomics 100%
  • Polysaccharides 61%
  • Glycoprotein 45%
  • Technology 43%
  • Glycoproteins 42%
  27 Citationer (Scopus)

• Direct quality control of glycoengineered erythropoietin variants

  Čaval, T., Tian, W., Yang, Z., Clausen, H. & Heck, A. J. R., 2018, I: Nature Communications. 9, 8 s., 3342.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Erythropoietin 100%
  • quality control 78%
  • Glycosylation 72%
  • Quality Control 68%
  • profiles 37%
  27 Citationer (Scopus)

  49 Downloads (Pure)

• EDEM1’s mannosidase-like domain binds ERAD client proteins in a redox-sensitive manner and possesses catalytic activity

  Lamriben, L., Oster, M. E., Tamura, T., Tian, W., Yang, Z., Clausen, H. & Hebert, D. N., 7 sep. 2018, I: Journal of Biological Chemistry. 293, 36, s. 13932-13945 14 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Mannosidases 100%
  • Oxidation-Reduction 57%
  • Proteolysis 56%
  • Protein 24%
  • Proteins 22%
  15 Citationer (Scopus)

• Expression of the O-Glycosylation Enzyme GalNAc-T3 in the Equatorial Segment Correlates with the Quality of Spermatozoa

  Nygaard, M. B., Herlihy, A. S., Jeanneau, C., Nielsen, J. E., Bennett, E. P., Jørgensen, N., Clausen, H., Mandel, U., Rajpert-De Meyts, E. & Almstrup, K., okt. 2018, I: International Journal of Molecular Sciences (Online). 19, 10, s. 1-13 2949.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glycosylation 100%
  • Immunohistochemistry 96%
  • polypeptide N-acetylgalactosaminyltransferase 95%
  • spermatozoa 86%
  • Enzymes 65%
  2 Citationer (Scopus)

  44 Downloads (Pure)

• Fine-Tuning Limited Proteolysis: A Major Role for Regulated Site-Specific O-Glycosylation

  Goth, C. K., Vakhrushev, S. Y., Joshi, H. J., Clausen, H. & Schjoldager, K. T., 2018, I: Trends in Biochemical Sciences. 43, 4, s. 269-284 16 s.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Limited Proteolysis 100%
  • Glycosylation 79%
  • Proteolysis 73%
  • Post-Translational Protein Modification 60%
  • Metalloproteases 55%
  21 Citationer (Scopus)

• GlycoDomainViewer: A bioinformatics tool for contextual exploration of glycoproteomes

  Joshi, H. J., Jørgensen, A., Schjoldager, K. T., Halim, A., Dworkin, L. A., Steentoft, C., Wandall, H. H., Clausen, H. & Vakhrushev, S. Y., 1 mar. 2018, I: Glycobiology. 28, 3, s. 131-136 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glycosylation 100%
  • Computational Biology 91%
  • Datasets 51%
  • Fucose 42%
  • Mannose 37%
  13 Citationer (Scopus)

• Glycoengineering design options for IgG1 in CHO cells using precise gene editing

  Schulz, M. A., Tian, W., Mao, Y., Van Coillie, J., Sun, L., Larsen, J. S., Chen, Y-H., Kristensen, C., Vakhrushev, S. Y., Clausen, H. & Yang, Z., 1 jul. 2018, I: Glycobiology. 28, 7, s. 542–549

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • N-Glycan 100%
  • Gene Editing 96%
  • CHO Cells 94%
  • Polysaccharides 73%
  • Immunoglobulin G 59%
  16 Citationer (Scopus)

• Glycosyltransferase genes that cause monogenic congenital disorders of glycosylation are distinct from glycosyltransferase genes associated with complex diseases

  Joshi, H. J., Hansen, L., Narimatsu, Y., Freeze, H. H., Henrissat, B., Bennett, E., Wandall, H. H., Clausen, H. & Schjoldager, K. T., 1 maj 2018, I: Glycobiology. 28, 5, s. 284-294

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Congenital Disorders of Glycosylation 100%
  • Glycosyltransferases 86%
  • Genome-Wide Association Study 67%
  • Glycosylation 63%
  • Disorder 55%
  20 Citationer (Scopus)

• Mucins and Truncated O-Glycans Unveil Phenotypic Discrepancies between Serous Ovarian Cancer Cell Lines and Primary Tumours

  Coelho, R., Marcos-Silva, L., Mendes, N., Pereira, D., Brito, C., Jacob, F., Steentoft, C., Mandel, U., Clausen, H., David, L. & Ricardo, S., 13 jul. 2018, I: International Journal of Molecular Sciences . 19, 7, s. 1-13 2045.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • O-Glycan 100%
  • cultured cells 81%
  • Glycosylation 80%
  • Mucins 73%
  • Tumors 70%
  8 Citationer (Scopus)

  82 Downloads (Pure)

• Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions

  Wang, S., Mao, Y., Narimatsu, Y., Ye, Z., Tian, W., Goth, C. K., Lira-Navarrete, E., Pedersen, N. B., Benito-Vicente, A., Martin, C., Uribe, K. B., Hurtado-Guerrero, R., Christoffersen, C., Seidah, N. G., Nielsen, R., Christensen, E. I., Hansen, L., Bennett, E. P., Vakhrushev, S. Y., Schjoldager, K. T., & 1 flereClausen, H., 11 maj 2018, I: The Journal of Biological Chemistry. 293, 19, s. 7408 –7422

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Low-Density Lipoprotein 100%
  • LDL Receptors 99%
  • Glycosylation 88%
  • Ligands 60%
  • LDL-Receptor Related Proteins 48%
  30 Citationer (Scopus)

• Site-specific O-glycosylation of N-terminal serine residues by polypeptide GalNAc-transferase 2 modulates human δ-opioid receptor turnover at the plasma membrane

  Lackman, J. J., Goth, C. K., Halim, A., Vakhrushev, S. Y., Clausen, H. & Petäjä-Repo, U. E., jan. 2018, I: Cellular Signalling. 42, s. 184-193 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • polypeptide N-acetylgalactosaminyltransferase 100%
  • Opioid Receptors 66%
  • Glycosylation 61%
  • Serine 57%
  • Cell Membrane 43%
  14 Citationer (Scopus)

• SnapShot: O-Glycosylation Pathways across Kingdoms

  Joshi, H. J., Narimatsu, Y., Schjoldager, K. T., Tytgat, H. L. P., Aebi, M., Clausen, H. & Halim, A., 25 jan. 2018, I: Cell. 172, 3, s. 632–632.e2

  Publikation: Bidrag til tidsskrift › Review › peer review

  • O-Glycan 100%
  • Glycosylation 70%
  • Polysaccharides 64%
  • Biosynthetic Pathways 41%
  • Protein Stability 40%
  30 Citationer (Scopus)

• Structural analysis of a GalNAc-T2 mutant reveals an induced-fit catalytic mechanism for GalNAc-Ts

  de Las Rivas, M., Coelho, H., Diniz, A., Lira-Navarrete, E., Compañón, I., Jiménez-Barbero, J., T Schjoldager, K., P Bennett, E., Y Vakhrushev, S., Clausen, H., Corzana, F., Marcelo, F. & Hurtado-Guerrero, R., 12 jun. 2018, I: Chemistry: A European Journal. 24, 33, s. 8382-8392

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Enzymes 100%
  • Structural analysis 88%
  • Glycosylation 61%
  • Nuclear magnetic resonance spectroscopy 52%
  • Mutation 49%
  10 Citationer (Scopus)

• Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4

  De Las Rivas, M., Paul Daniel, E. J., Coelho, H., Lira-Navarrete, E., Raich, L., Compañón, I., Diniz, A., Lagartera, L., Jiménez-Barbero, J., Clausen, H., Rovira, C., Marcelo, F., Corzana, F., Gerken, T. A. & Hurtado-Guerrero, R., 2018, I: A C S Central Science. 4, 9, s. 1274-1290 17 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Lectins 100%
  • Glycosylation 93%
  • Lectin 54%
  • Glycopeptides 42%
  • Glycopeptide 29%
  21 Citationer (Scopus)

  54 Downloads (Pure)

• The GAGOme: a cell-based library of displayed glycosaminoglycans

  Chen, Y-H., Narimatsu, Y., Clausen, T. M., Gomes, C., Karlsson, R., Steentoft, C., Spliid, C. B., Gustavsson, T., Salanti, A., Persson, A., Malmström, A., Willén, D., Ellervik, U., Bennett, E. P., Mao, Y., Clausen, H. & Yang, Z., 1 nov. 2018, I: Nature Methods. 15, 11, s. 881-888

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glycosaminoglycan 100%
  • Glycosaminoglycans 91%
  • Libraries 76%
  • Polysaccharides 16%
  • Gene Knock-In Techniques 14%
  36 Citationer (Scopus)
• 2017

  Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins

  Larsen, I. S. B., Narimatsu, Y., Joshi, H. J., Siukstaite, L., Harrison, O. J., Brasch, J., Goodman, K. M., Hansen, L., Shapiro, L., Honig, B., Vakhrushev, S. Y., Clausen, H. & Halim, A., 17 okt. 2017, I: Proceedings of the National Academy of Sciences of the United States of America. 114, 42, s. 11163-11168 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Mannose 100%
  • Cadherins 86%
  • Glycosylation 48%
  • Polysaccharides 29%
  • Cobblestone Lissencephaly 14%
  35 Citationer (Scopus)

• Fine-tuning limited proteolysis - A novel role for regulated site-specific O-glycosylation in beta 1-Adrenergic Receptor cleavage and function

  Goth, C. K., Tuhkanen, H. E., Khan, H., Wang, S., Narimatsu, Y., Hansen, L. H., Overall, C., Clausen, H., Schjoldager, K. T. & Petaja-Repo, U., dec. 2017, I: Glycobiology. 27, 12, s. 1204-1204 84.

  Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning › peer review

• Generation and characterization of a monoclonal antibody to the cytoplasmic tail of MUC16

  Gipson, I. K., Mandel, U., Menon, B., Michaud, S., Tisdale, A., Campos, D. & Clausen, H., 1 okt. 2017, I: Glycobiology. 27, 10, s. 920-926 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Mucins 100%
  • Monoclonal Antibodies 67%
  • Ocular 59%
  • Epithelium 35%
  • Eye 28%
  4 Citationer (Scopus)

• Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis

  Lonowski, L. A., Narimatsu, Y., Riaz, A., Delay, C. M. E., Yang, Z., Niola, F., Duda, K., Ober, E. A., Clausen, H., Wandall, H. H., Hansen, S. H., Bennett, E. P. & Frödin, M., 1 mar. 2017, I: Nature Protocols. 12, 3, s. 581-603 23 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Gene Editing 100%
  • Pipeline 94%
  • Clustered Regularly Interspaced Short Palindromic Repeats 62%
  • Cell Line 48%
  • Effector 44%
  54 Citationer (Scopus)

• Glycosylation Engineering

  Clausen, H., Wandall, H. H., Steentoft, C., Stanley, P. & Schnaar, R. L., 2017, Essentials of Glycobiology. 3 udg. Cold Spring Harbor Laboratory Press

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

  • Glycosylation 100%
  • Plant Cells 23%
  • Genetic engineering 22%
  • Phylogeny 20%
  • Fungi 19%

• Identification and evolution of a plant cell wall specific glycoprotein glycosyl transferase, ExAD

  Möller, S. R., Yi, X., Vel?squez, S. M., Gille, S., Hansen, P., Poulsen, C. P., Olsen, C. E., Rejzek, M., Parsons, H. T., Yang, Z., Wandall, H. H., Clausen, H., Field, R. A., Pauly, M., Estevez, J. M., Harholt, J., Ulvskov, P. & Petersen, B. L., 30 mar. 2017, I: Scientific Reports. 7, 16 s., 45341.

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  • Plant Cells 100%
  • Charophyceae 77%
  • Transferases 75%
  • Cell Wall 74%
  • Viridiplantae 65%
  20 Citationer (Scopus)

  116 Downloads (Pure)

• Mammalian O-mannosylation of Cadherins and Plexins is Independent of Protein O-mannosyltransferase 1 and 2

  Larsen, I. S. B., Narimatsu, Y., Joshi, H. J., Yang, Z., Harrison, O. J., Brasch, J., Shapiro, L., Honig, B., Vakhrushev, S. Y., Clausen, H. & Halim, A., 7 jul. 2017, I: The Journal of Biological Chemistry. 292, s. 11586-11598

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • protein O-mannosyltransferase 100%
  • plexin 83%
  • Mannose 61%
  • Cadherins 53%
  • Dystroglycans 34%
  20 Citationer (Scopus)

• NleB/SseK effectors from Citrobacter rodentium, Escherichia coli, and Salmonella enterica display distinct differences in host substrate specificity

  El Qaidi, S., Chen, K., Halim, A., Siukstaite, L., Rueter, C., Hurtado-Guerrero, R., Clausen, H. & Hardwidge, P. R., 7 jul. 2017, I: The Journal of Biological Chemistry. 292, s. 11423-11430

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  • Citrobacter rodentium 100%
  • Enterohemorrhagic Escherichia coli 84%
  • Host Specificity 76%
  • Salmonella enterica 75%
  • Substrate Specificity 69%
  32 Citationer (Scopus)

• Revisiting the human polypeptide GalNAc-T1 and T13 paralogs

  Festari, M. F., Trajtenberg, F., Berois, N., Pantano, S., Revoredo, L., Kong, Y., Solari-Saquieres, P., Narimatsu, Y., Freire, T., Bay, S., Robello, C., Bénard, J., Gerken, T. A., Clausen, H. & Osinaga, E., jan. 2017, I: Glycobiology. 27, 2, s. 140-153 14 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • polypeptide N-acetylgalactosaminyltransferase 100%
  • Polypeptide 49%
  • Protein Isoforms 48%
  • Substrate Specificity 44%
  • Glycosylation 40%
  7 Citationer (Scopus)

• Site-specific O-Glycosylation by Polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-transferase T2) Co-regulates β1-Adrenergic Receptor N-terminal Cleavage

  Goth, C. K., Tuhkanen, H. E., Khan, H., Lackman, J. J., Wang, S., Narimatsu, Y., Hansen, L. H., Overall, C. M., Clausen, H., Schjoldager, K. T. & Petäjä-Repo, U. E., 17 mar. 2017, I: The Journal of Biological Chemistry. 292, 11, s. 4714-4726 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • polypeptide N-acetylgalactosaminyltransferase 100%
  • Glycosylation 61%
  • Adrenergic Receptors 56%
  • Polypeptide 49%
  • Cleavage 40%
  17 Citationer (Scopus)

• Spatial separation of the cyanogenic β-glucosidase ZfBGD2 and cyanogenic glucosides in the haemolymph of Zygaena larvae facilitates cyanide release

  Pentzold, S., Jensen, M. K., Matthes, A., Olsen, C. E., Petersen, B. L., Clausen, H., Møller, B. L., Bak, S. & Zagrobelny, M., 28 jun. 2017, I: Royal Society Open Science. 4, 13 s., 170262.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glucosidases 100%
  • Hemolymph 90%
  • Glucosides 88%
  • Cyanides 86%
  • Larva 70%
  9 Citationer (Scopus)

  80 Downloads (Pure)

• The GOLPH3 oncogene controls the intra-Golgi recycling of sphingolipid glycosylating enzymes to promote proliferation

  Rizzo, R., Supino, D., Lombardi, B., Russo, D., Russo, F., Zhukovsky, M., Pothukuchi, P., Sticco, L., Capasso, S., Capolupo, L., Boncompain, G., Dathan, N., Turacchio, G., Marino, F. Z., Acquino, G., Vitagliano, C., Henklein, P., Clausen, H., Mandel, U., Budillon, A., & 6 flereParashuraman, S., Perez, F., Obeid, L. M., Hannun, Y. A., Luini, A. & D'Angelo, G., 2017, I: Molecular Biology of the Cell. 28, 26, s. 348 P2418.

  Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning › peer review

  4 Citationer (Scopus)

• The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences

  Rivas, M. D. L., Lira-Navarrete, E., Daniel, E. J. P., Companõn, I., Coelho, H., Diniz, A., Jiménez-Barbero, J., Peregrina, J. M., Clausen, H., Corzana, F., Marcelo, F., Jiménez-Osés, G., Gerken, T. A. & Hurtado-Guerrero, R., dec. 2017, I: Nature Communications. 8, 1, 11 s., 1959.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • polypeptide N-acetylgalactosaminyltransferase 100%
  • polypeptides 73%
  • Glycosylation 61%
  • Lectin 61%
  • Polypeptide 49%
  22 Citationer (Scopus)

  50 Downloads (Pure)
• 2016

  Distinguishing Truncated and Normal MUC1 Glycoform Targeting from Tn-MUC1-Specific CAR T Cells: Specificity Is the Key to Safety

  Posey, A. D., Clausen, H. & June, C. H., 15 nov. 2016, I: Immunity. 45, 5, s. 947-948 2 s.

  Publikation: Bidrag til tidsskrift › Letter › peer review

  • T-Cell Antigen Receptor Specificity 100%
  • Chimeric Antigen Receptors 94%
  • Safety 40%
  • Single-Chain Antibodies 29%
  • Immunoglobulin Fragments 29%
  19 Citationer (Scopus)

• Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma

  Posey, A. D., Schwab, R. D., Boesteanu, A. C., Steentoft, C., Mandel, U., Engels, B., Stone, J. D., Madsen, T. D., Schreiber, K., Haines, K. M., Cogdill, A. P., Chen, T. J., Song, D., Scholler, J., Kranz, D. M., Feldman, M. D., Young, R., Keith, B., Schreiber, H., Clausen, H., & 2 flereJohnson, L. A. & June, C. H., 21 jun. 2016, I: Immunity. 44, 6, s. 1444-1454 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Chimeric Antigen Receptors 100%
  • Mucins 79%
  • Adenocarcinoma 58%
  • T-Lymphocytes 45%
  • Membranes 44%
  257 Citationer (Scopus)

• Extrinsic functions of lectin domains in O-N-acetylgalactosamine glycan biosynthesis

  Lorenz, V., Ditamo, Y., Cejas, R. B., Carrizo, M. E., Bennett, E. P., Clausen, H., Nores, G. A. & Irazoqui, F. J., 2 dec. 2016, I: Journal of Biological Chemistry. 291, s. 25339-25350 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Acetylgalactosamine 100%
  • Lectins 72%
  • Lectin 71%
  • Polysaccharides 65%
  • Biosynthesis 58%
  7 Citationer (Scopus)

• Lepidopteran defence droplets - a composite physical and chemical weapon against potential predators

  Pentzold, S., Zagrobelny, M., Khakimov, B., Engelsen, S. B., Clausen, H., Petersen, B. L., Borch, J., Møller, B. L. & Bak, S., 4 mar. 2016, I: Scientific Reports. 6, 11 s., 22407 .

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hydrogen Cyanide 100%
  • Weapons 98%
  • Glucosidases 89%
  • Glucosides 78%
  • Hemolymph 54%
  13 Citationer (Scopus)

  111 Downloads (Pure)

• Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents

  Khetarpal, S. A., Schjoldager, K. T., Christoffersen, C., Raghavan, A., Edmondson, A. C., Reutter, H. M., Ahmed, B., Ouazzani, R., Peloso, G. M., Vitali, C., Zhao, W., Somasundara, A. V. H., Millar, J. S., Park, Y., Fernando, G., Livanov, V., Choi, S., Noé, E., Patel, P., Ho, S. P., & 12 flereKirchgessner, T. G., Wandall, H. H., Hansen, L., Bennett, E. P., Vakhrushev, S. Y., Saleheen, D., Kathiresan, S., Brown, C. D., Abou Jamra, R., LeGuern, E., Clausen, H. & Rader, D. J., 9 aug. 2016, I: Cell Metabolism. 24, 2, s. 234-245 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • HDL Lipoproteins 100%
  • Primates 88%
  • HDL Cholesterol 84%
  • Rodentia 78%
  • polypeptide N-acetylgalactosaminyltransferase 63%
  66 Citationer (Scopus)

• Mapping the O-Mannose Glycoproteome in Saccharomyces cerevisiae

  Neubert, P., Halim, A., Zauser, M., Essig, A., Joshi, H. J., Zatorska, E., Larsen, I. S. B., Loibl, M., Castells-Ballester, J., Aebi, M., Clausen, H. & Strahl, S., apr. 2016, I: Molecular and Cellular Proteomics. 15, 4, s. 1323-37 15 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Mannose 100%
  • Glycosylation 88%
  • Saccharomyces cerevisiae 79%
  • Modification 47%
  • Protein 35%
  37 Citationer (Scopus)

  89 Downloads (Pure)

• Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer

  Krishn, S. R., Kaur, S., Smith, L. M., Johansson, S. L., Jain, M., Patel, A., Gautam, S. K., Hollingsworth, M. A., Mandel, U., Clausen, H., Lo, W-C., Fan, W-T. L., Manne, U. & Batra, S. K., 1 maj 2016, I: Cancer Letters. 374, 2, s. 304-14 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Mucins 100%
  • Early Detection of Cancer 88%
  • Polysaccharides 87%
  • Adenoma 86%
  • Colonic Neoplasms 84%
  32 Citationer (Scopus)

• Mucin-type O-glycosylation is controlled by short- and long-range glycopeptide substrate recognition that varies among members of the polypeptide GalNAc transferase family

  Revoredo, L., Wang, S., Bennett, E. P., Clausen, H., Moremen, K. W., Jarvis, D. L., Ten Hagen, K. G., Tabak, L. A. & Gerken, T. A., 1 apr. 2016, I: Glycobiology. 26, 4, s. 360-376 17 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • polypeptide N-acetylgalactosaminyltransferase 100%
  • Glycopeptides 75%
  • Glycopeptide 67%
  • Mucins 64%
  • Glycosylation 61%
  45 Citationer (Scopus)
• 2015

  A glycogene mutation map for discovery of diseases of glycosylation

  Hansen, L., Lind-Thomsen, A., Joshi, H. J., Pedersen, N. B., Have, C. T., Kong, Y., Wang, S., Sparso, T., Grarup, N., Vester-Christensen, M. B., Schjoldager, K., Freeze, H. H., Hansen, T., Pedersen, O., Henrissat, B., Mandel, U., Clausen, H., Wandall, H. H. & Bennett, E. P., 1 feb. 2015, I: Glycobiology. 25, 2, s. 211-224 14 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Congenital Disorders of Glycosylation 100%
  • Glycosylation 88%
  • Glycosyltransferases 86%
  • Isoenzymes 85%
  • Mutation 72%
  31 Citationer (Scopus)