Tugce Karaderi

2019

Cyprus Women's Health Research (COHERE) initiative: determining the relative burden of women's health conditions and related co-morbidities in an Eastern Mediterranean population

Hocaoglu, M. B., Gurkas, S., Karaderi, T., Taneri, B., Erguler, K., Barin, B., Bilgin, E. M., Eralp, G., Allison, M., Findikli, N., Boynukalin, K., Bahceci, M., Naci, H., Vincent, K., Missmer, S. A., Becker, C. M., Zondervan, K. T. & Rahmioglu, N., 3 Apr 2019, In: BMC Women's Health. 19, 7 p., 50.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Downloads (Pure)

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

Spracklen, C. N., Karaderi, T., Yaghootkar, H., Schurmann, C., Fine, R. S., Kutalik, Z., Preuss, M. H., Lu, Y., Wittemans, L. B. L., Adair, L. S., Allison, M., Amin, N., Auer, P. L., Bartz, T. M., Blüher, M., Boehnke, M., Borja, J. B., Bork-Jensen, J., Broer, L. & Chasman, D. I. & 31 others, Chen, Y. D. I., Chirstofidou, P., Demirkan, A., van Duijn, C. M., Feitosa, M. F., Garcia, M. E., Graff, M., Grallert, H., Grarup, N., Guo, X., Haesser, J., Hansen, T., Harris, T. B., Highland, H. M., Hong, J., Ikram, M. A., Ingelsson, E., Jackson, R., Jousilahti, P., Kähönen, M., Kizer, J. R., Kovacs, P., Kriebel, J., Laakso, M., Lange, L. A., Lehtimäki, T., Li, J., Lind, L., Kilpeläinen, T. O., Loos, R. J. F. & Mohlke, K. L., 2019, In: American Journal of Human Genetics. 105, 1, p. 15-28 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration

Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Jennison, C., Ehrhardt, B., Baum, P., Schoelsch, C., Freijer, J., Grempler, R., Graefe-Mody, U., Hennige, A., Dings, C., Lehr, T., Scherer, N., Sihinecich, I., Pattou, F. & Raverdi, V. & 31 others, Caiazzo, R., Torres, F., Verkindt, H., Mari, A., Tura, A., Giorgino, T., Bizzotto, Froguel, P., Brorsson, C., Brunak, S., De Masi, F., Pedersen, H., Banasik, K., Thomas, C., Lundgaard, A., Nielsen, A., Mazzoni, G., Karaderi, T., Rasmussen, S., Johansen, J., Allesøe, R., Arumugam, M., Allin, K., Hansen, T., Hansen, T., Jonsson, A., Pedersen, O., Dutta, A., Vogt, J., Vestergaard, H. & IMI-DIRECT consortium, 1 Sept 2019, In: Journal of Hepatology. 71, 3, p. 594-602 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

13 Downloads (Pure)

The severity of ankylosing spondylitis and responses to anti-tumour necrosis factor biologics are not influenced by the tumour necrosis factor receptor polymorphism incriminated in multiple sclerosis

Watts, L., Karaderi, T., Roberts, A., Appleton, L., Wordsworth, T., Cohen, C., Wordsworth, P. & Vecellio, M., 2019, In: Genes and Immunity. 20, p. 167-171 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

2018

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

Day, F., Karaderi, T., Jones, M. R., Meun, C., He, C., Drong, A., Kraft, P., Lin, N., Huang, H., Broer, L., Magi, R., Saxena, R., Laisk, T., Urbanek, M., Hayes, M. G., Thorleifsson, G., Fernandez-Tajes, J., Mahajan, A., Mullin, B. H. & Stuckey, B. G. A. & 30 others, Spector, T. D., Wilson, S. G., Goodarzi, M. O., Davis, L., Obermayer-Pietsch, B., Uitterlinden, A. G., Anttila, V., Neale, B. M., Jarvelin, M. R., Fauser, B., Kowalska, I., Visser, J. A., Andersen, M., Ong, K., Stener-Victorin, E., Ehrmann, D., Legro, R. S., Salumets, A., McCarthy, M. I., Morin-Papunen, L., Thorsteinsdottir, U., Stefansson, K., Styrkarsdottir, U., Perry, J. R. B., Dunaif, A., Laven, J., Franks, S., Lindgren, C. M., Welt, C. K. & the 23andMe Research Team, 2018, In: PLOS Genetics. 14, 12, 20 p., e1007813.

Research output: Contribution to journal › Journal article › Research › peer-review

88 Citations (Scopus)

2017

Rare and low-frequency coding variants alter human adult height

Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T. & Karaderi, T. & 31 others, Locke, A. E., Masca, N. G. D., Ng, M. C. Y., Mudgal, P., Rivas, M. A., Vedantam, S., Mahajan, A., Guo, X., Abecasis, G., Aben, K. K., Allin, K. H., Appel, E. V., Bang, L. E., Benn, M., Bork-Jensen, J., Frikke-Schmidt, R., Grarup, N., Hansen, T., Hollensted, M., Jensen, G. B., Jørgensen, M. E., Jørgensen, T., Kamstrup, P. R., Linneberg, A., Nielsen, S. F., Nordestgaard, B. G., Pedersen, O., Tybjaerg-Hansen, A., Vestergaard, H., Pers, T. H. & EPIC-InterAct Consortium, 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

277 Citations (Scopus)

Sexual dimorphisms in genetic loci linked to body fat distribution

Pulit, S. L., Karaderi, T. & Lindgren, C. M., 2017, In: Bioscience Reports. 37, 1, BSR20160184.

Research output: Contribution to journal › Review › peer-review

30 Citations (Scopus)

2016

Testing the role of predicted gene knockouts in human anthropometric trait variation

NHLBI GO Exome Sequence Project, GOT2D, T2D-GENES & GIANT Consortium, 15 May 2016, In: Human Molecular Genetics. 25, 10, p. 2082-2092 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

2015

Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations

Hayes, M. G., Urbanek, M., Ehrmann, D. A., Armstrong, L. L., Lee, J. Y., Sisk, R., Karaderi, T., Barber, T. M., McCarthy, M. I., Franks, S., Lindgren, C. M., Welt, C. K., Diamanti-Kandarakis, E., Panidis, D., Goodarzi, M. O., Azziz, R., Zhang, Y., James, R. G., Olivier, M. & Kissebah, A. H. & 30 others, Stener-Victorin, E., Legro, R. S., Dunaif, A., Alvero, R., Barnhart, H. X., Baker, V., Barnhart, K. T., Bates, G. W., Brzyski, R. G., Carr, B. R., Carson, S. A., Casson, P., Cataldo, N. A., Christman, G., Coutifaris, C., Diamond, M. P., Eisenberg, E., Gosman, G. G., Giudice, L. C., Haisenleder, D. J., Huang, H., Krawetz, S. A., Lucidi, S., McGovern, P. G., Myers, E. R., Nestler, J. E., Ohl, D., Santoro, N., Schlaff, W. D. & Snyder, P., 18 Aug 2015, In: Nature Communications. 6, 7502.

Research output: Contribution to journal › Journal article › Research › peer-review

170 Citations (Scopus)

Insights into the Genetic Susceptibility to Type 2 Diabetes from Genome-Wide Association Studies of Obesity-Related Traits

Karaderi, T., Drong, A. W. & Lindgren, C. M., 22 Oct 2015, In: Current Diabetes Reports. 15, 10, 83.

Research output: Contribution to journal › Review › peer-review

38 Citations (Scopus)

2014

Ankylosing spondylitis is associated with the anthrax toxin receptor 2 gene (ANTXR2)

Karaderi, T., Keidel, S. M., Pointon, J. J., Appleton, L. H., Brown, M. A., Evans, D. M. & Wordsworth, B. P., 1 Nov 2014, In: Annals of the Rheumatic Diseases. 73, 11, p. 2054-2058 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

2013

A CCR6 variant strongly associated with rheumatoid arthritis in two populations is not associated with ankylosing spondylitis

Cohen, C. J., Karaderi, T., Pointon, J. J. & Wordsworth, B. P., 1 Sept 2013, In: Rheumatology International. 33, 9, p. 2443-2444 2 p.

Research output: Contribution to journal › Letter › peer-review

2 Citations (Scopus)

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

Cortes, A., Hadler, J., Pointon, J. P., Robinson, P. C., Karaderi, T., Leo, P., Cremin, K., Pryce, K., Harris, J., Lee, S., Joo, K. B., Shim, S. C., Weisman, M., Ward, M., Zhou, X., Garchon, H. J., Chiocchia, G., Nossent, J., Lie, B. A. & Førre, Ø. & 30 others, Tuomilehto, J., Laiho, K., Jiang, L., Liu, Y., Wu, X., Bradbury, L. A., Elewaut, D., Burgos-Vargas, R., Stebbings, S., Appleton, L., Farrah, C., Lau, J., Kenna, T. J., Haroon, N., Ferreira, M. A., Yang, J., Mulero, J., Fernandez-Sueiro, J. L., Gonzalez-Gay, M. A., Lopez-Larrea, C., Deloukas, P., Donnelly, P., Bowness, P., Gafney, K., Gaston, H., Gladman, D. D., Rahman, P., Maksymowych, W. P., Xu, H. & Crusius, J. B. A., 1 Jul 2013, In: Nature Genetics. 45, 7, p. 730-738 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

466 Citations (Scopus)

2012

Evidence of genetic association between TNFRSF1A encoding the p55 tumour necrosis factor receptor, and ankylosing spondylitis in UK Caucasians

Karaderi, T., Pointon, J. J., Wordsworth, T. W. H., Harvey, D., Appleton, L. H., Cohen, C. J., Farrar, C., Harin, A., Brown, M. A. & Wordsworth, B. P., 17 Jul 2012, In: Clinical and Experimental Rheumatology. 30, 1, p. 110-113 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

2011

A common functional variant of endoplasmic reticulum aminopeptidase 2 (ERAP2) that reduces major histocompatibility complex class I expression is not associated with ankylosing spondylitis

Harvey, D., Pointon, J. J., Karaderi, T., Appleton, L. H., Farrar, C. & Paul Wordsworth, B., 1 Sept 2011, In: Rheumatology. 50, 9, p. 1720-1721 2 p., ker199.

Research output: Contribution to journal › Letter › peer-review

13 Citations (Scopus)

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

Evans, D. M., Spencer, C. C. A., Pointon, J. J., Su, Z., Harvey, D., Kochan, G., Opperman, U., Dilthey, A., Pirinen, M., Stone, M. A., Appleton, L., Moutsianis, L., Leslie, S., Wordsworth, T., Kenna, T. J., Karaderi, T., Thomas, G. P., Ward, M. M., Weisman, M. H. & Farrar, C. & 30 others, Bradbury, L. A., Danoy, P., Inman, R. D., Maksymowych, W., Gladman, D., Rahman, P., Morgan, A., Marzo-Ortega, H., Bowness, P., Gaffney, K., Gaston, J. S. H., Smith, M., Bruges-Armas, J., Couto, A. R., Sorrentino, R., Paladini, F., Ferreira, M. A., Xu, H., Liu, Y., Jiang, L., Lopez-Larrea, C., Díaz-Peña, R., Lóepez-Vázquez, A., Zayats, T., Band, G., Bellenguez, C., Blackburn, H., Blackwell, J. M., Bramon, E. & Bumpstead, S. J., 1 Aug 2011, In: Nature Genetics. 43, 8, p. 761-767 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

570 Citations (Scopus)

The histone demethylase JARID1A is associated with susceptibility to ankylosing spondylitis

Pointon, J. J., Harvey, D., Karaderi, T., Appleton, L. H., Farrar, C. & Wordsworth, B. P., 1 Jul 2011, In: Genes and Immunity. 12, 5, p. 395-398 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

2010

Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene

Pointon, J. J., Harvey, D., Karaderi, T., Appleton, L. H., Farrar, C., Stone, M. A., Sturrock, R. D., Brown, M. A. & Wordsworth, B. P., 1 Jan 2010, In: Genes and Immunity. 11, 6, p. 490-496 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

51 Citations (Scopus)

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

Reveille, J. D., Sims, A. M., Danoy, P., Evans, D. M., Leo, P., Pointon, J. J., Jin, R., Zhou, X., Bradbury, L. A., Appleton, L. H., Davis, J. C., Diekman, L., Doan, T., Dowling, A., Duan, R., Duncan, E. L., Farrar, C., Hadler, J., Harvey, D. & Karaderi, T. & 19 others, Mogg, R., Pomeroy, E., Pryce, K., Taylor, J., Savage, L., Deloukas, P., Kumanduri, V., Peltonen, L., Ring, S. M., Whittaker, P., Glazov, E., Thomas, G. P., Maksymowych, W. P., Inman, R. D., Ward, M. M., Stone, M. A., Weisman, M. H., Wordsworth, B. P. & Brown, M. A., 1 Feb 2010, In: Nature Genetics. 42, 2, p. 123-127 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

453 Citations (Scopus)

The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-associated death domain (TRADD)

Pointon, J. J., Harvey, D., Karaderi, T., Appleton, L. H., Farrar, C., Stone, M. A., Sturrock, R. D., Reveille, J. D., Weisman, M. H., Ward, M. M., Brown, M. A. & Wordsworth, B. P., 1 Jun 2010, In: Annals of the Rheumatic Diseases. 69, 6, p. 1243-1246 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

2009

Association between the interleukin 23 receptor and ankylosing spondylitis is confirmed by a new UK case-control study and meta-analysis of published series

Karaderi, T., Harvey, D., Farrar, C., Appleton, L. H., Stone, M. A., Sturrock, R. D., Brown, M. A., Wordsworth, P. & Pointon, J. J., 2 Apr 2009, In: Rheumatology. 48, 4, p. 386-389 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

89 Citations (Scopus)

Investigating the genetic association between ERAP1 and ankylosing spondylitis

Harvey, D., Pointon, J. J., Evans, D. M., Karaderi, T., Farrar, C., Appleton, L. H., Sturrock, R. D., Stone, M. A., Oppermann, U., Brown, M. A. & Wordsworth, B. P., 20 Oct 2009, In: Human Molecular Genetics. 18, 21, p. 4204-4212 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

100 Citations (Scopus)

Tugce Karaderi

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