Søren Bak

2019

Evolution of Structural Diversity of Triterpenoids

Cárdenas, P. D., Almeida, A. & Bak, S., 17 Dec 2019, In: Frontiers in Plant Science. 10, p. 1-10 1523.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

4 Downloads (Pure)

Sequestration and biosynthesis of cyanogenic glucosides in passion vine butterflies and consequences for the diversification of their host plants

Pinheiro de Castro, É. C., Zagrobelny, M., Zurano, J. P., Zikan Cardoso, M., Feyereisen, R. & Bak, S., 1 May 2019, In: Ecology and Evolution. 9, 9, p. 5079-5093

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

25 Downloads (Pure)

The cytochrome P450 CYP72A552 is key to production of hederagenin‐based saponins that mediate plant defense against herbivores

Liu, Q., Khakimov, B., Cárdenas, P. D., Cozzi, F., Olsen, C. E., Jensen, K. R., Hauser, T. P. & Bak, S., May 2019, In: New Phytologist (Online). 222, 3, p. 1599-1609

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

116 Downloads (Pure)

2018

A Single Oxidosqualene Cyclase Produces the Seco-Triterpenoid α-Onocerin

Almeida, A., Dong, L., Khakimov, B., Bassard, J-É. A., Moses, T., Lota, F., Goossens, A., Appendino, G. & Bak, S., Feb 2018, In: Plant Physiology. 176, 2, p. 1469-1484 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

A tandem array of UDP-glycosyltransferases from the UGT73C subfamily glycosylate sapogenins, forming a spectrum of mono- and bisdesmosidic saponins

Erthmann, P. Ø., Agerbirk, N. & Bak, S., 1 May 2018, In: Plant Molecular Biology. 97, 1-2, p. 37-55 19 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Co-expression of squalene epoxidases with triterpene cyclases boosts production of triterpenoids in plants and yeast

Dong, L., Pollier, J., Bassard, J-E., Ntallas, G., Almeida, A., Lazaridi, E., Khakimov, B., Arendt, P., de Oliveira, L. S., Lota, F., Goossens, A., Michoux, F. & Bak, S., Sept 2018, In: Metabolic Engineering. 49, p. 1-12

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Cyanogenesis in arthropods: from chemical warfare to nuptial gifts

Zagrobelny, M., Pinheiro de Castro, É. C., Møller, B. L. & Bak, S., Jun 2018, In: Insects. 9, 2, 39 p., 51.

Research output: Contribution to journal › Review › peer-review

16 Citations (Scopus)

68 Downloads (Pure)

Evolution of the biosynthetic pathway for cyanogenic glucosides in Lepidoptera

Zagrobelny, M., Jensen, M. K., Vogel, H., Feyereisen, R. & Bak, S., 1 Jul 2018, In: Journal of Molecular Evolution. 86, 6, p. 379-394 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Glucosinolate turnover in Brassicales species to an oxazolidin-2-one, formed via the 2-thione and without formation of thioamide

Agerbirk, N., Matthes, A., Erthmann, P. Ø., Ugolini, L., Cinti, S., Lazaridi, E., Nuzillard, J-M., Mueller, C., Bak, S., Rollin, P. & Lazzeri, L., Sept 2018, In: Phytochemistry. 153, p. 79-93

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

The arms race between heliconiine butterflies and Passiflora plants - new insights on an ancient subject

Pinheiro de Castro, É. C., Zagrobelny, M., Cardoso, M. Z. & Bak, S., 1 Feb 2018, In: Biological Reviews. 93, 1, p. 555-573 19 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

The TriForC database: a comprehensive up-to-date resource of plant triterpene biosynthesis

Miettinen, K. A., Inigo, S., Kreft, L., Pollier, J., De Bo, C., Botzki, A., Coppens, F., Bak, S. & Goossens, A., 1 Jan 2018, In: Nucleic Acids Research. 46, D1, p. D586-D594 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

69 Downloads (Pure)

Triterpene Messages from the EU-FP7 Project TriForC

Goossens, A., Osbourn, A., Michoux, F. & Bak, S., Apr 2018, In: Trends in Plant Science. 23, 4, p. 273-276

Research output: Contribution to journal › Editorial › peer-review

4 Citations (Scopus)

2017

Developmentally regulated glucosylation of bitter triterpenoid in cucumber by the Udp-Glucosyltransferase Ugt73am3

Zhong, Y., Xue, X., Liu, Z., Ma, Y., Zeng, K., Han, L., Qi, J., Ro, D-K., Bak, S., Huang, S., Zhou, Y. & Shang, Y., 5 Jul 2017, In: Molecular Plant. 10, 7, p. 1000-1003 4 p.

Research output: Contribution to journal › Letter › peer-review

9 Citations (Scopus)

Quinoa seed coats as an expanding and sustainable source of bioactive compounds: an investigation of genotypic diversity in saponin profiles

Ruiz, K. B., Khakimov, B., Engelsen, S. B., Bak, S., Biondi, S. & Jacobsen, S-E., 2017, In: Industrial Crops and Products. 104, p. 156-163 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Spatial separation of the cyanogenic β-glucosidase ZfBGD2 and cyanogenic glucosides in the haemolymph of Zygaena larvae facilitates cyanide release

Pentzold, S., Jensen, M. K., Matthes, A., Olsen, C. E., Petersen, B. L., Clausen, H., Møller, B. L., Bak, S. & Zagrobelny, M., 28 Jun 2017, In: Royal Society Open Science. 4, 13 p., 170262.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

80 Downloads (Pure)

The genome sequence of Barbarea vulgaris facilitates the study of ecological biochemistry

Byrne, S. L., Erthmann, P. Ø., Agerbirk, N., Bak, S., Hauser, T. P., Nagy, I., Paina, C. & Asp, T., 17 Jan 2017, In: Scientific Reports. 7, 14 p., 40728.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

81 Downloads (Pure)

2016

Lepidopteran defence droplets - a composite physical and chemical weapon against potential predators

Pentzold, S., Zagrobelny, M., Khakimov, B., Engelsen, S. B., Clausen, H., Petersen, B. L., Borch, J., Møller, B. L. & Bak, S., 4 Mar 2016, In: Scientific Reports. 6, 11 p., 22407 .

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

111 Downloads (Pure)

Screening for triterpenoid saponins in plants using hyphenated analytical platforms

Khakimov, B., Tseng, L. H., Godejohann, M., Bak, S. & Engelsen, S. B., Dec 2016, In: Molecules. 21, 12, 19 p., 1614.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

176 Downloads (Pure)

2015

Identification and genome organization of saponin pathway genes from a wild crucifer, and their use for transient production of saponins in Nicotiana benthamiana

Khakimov, B., Poulsen, V. K., Erthmann, P. Ø., Fukushima, E. O., Augustin, J. M., Olsen, C. E., Scholtalbers, J., Volpin, H., Andersen, S. B., Hauser, T. P., Muranaka, T. & Bak, S., Nov 2015, In: The Plant Journal. 84, 3, p. 478-490 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

50 Citations (Scopus)

Metabolism, excretion and avoidance of cyanogenic glucosides in insects with different feeding specialisations

Pentzold, S., Zagrobelny, M., Bjarnholt, N., Kroymann, J., Vogel, H., Olsen, C. E., Møller, B. L. & Bak, S., 1 Nov 2015, In: Insect Biochemistry and Molecular Biology. 66, p. 119-128 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

Multiple hydroxyphenethyl glucosinolate isomers and their tandem mass spectrometric destinction in a geographically structured polymorphism in the crucifer Barbarea vulgaris

Agerbirk, N., Olsen, C. E., Heimes, C., Christensen, S., Bak, S. & Hauser, T. P., 2015, In: Phytochemistry. 115, p. 130-142 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

The bifurcation of the cyanogenic glucoside and glucosinolate biosynthetic pathways

Clausen, M., Kannangara, R. M., Olsen, C. E., Blomstedt, C. K., Gleadow, R. M., Jørgensen, K., Bak, S., Motawie, M. S. & Møller, B. L., Nov 2015, In: The Plant Journal. 84, 3, p. 558-573 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Volatiles from the burnet Moth Zygaena filipendulae (Lepidoptera) and Associated flowers, and their involvement in mating communication

Zagrobelny, M., Simonsen, H. T., Olsen, C. E., Bak, S. & Møller, B. L., 1 Dec 2015, In: Physiological Entomology. 40, 4, p. 284-295 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

2014

Chemical defense balanced by sequestration and de novo biosynthesis in a lepidopteran specialist

Fürstenberg-Hägg, J., Zagrobelny, M., Jørgensen, K., Vogel, H., Møller, B. L. & Bak, S., 9 Oct 2014, In: P L o S One. 9, 10, 9 p., e108745.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

1824 Downloads (Pure)

High-throughput cereal metabolomics: current analytical technologies, challenges and perspectives

Khakimov, B., Bak, S. & Engelsen, S. B., May 2014, In: Journal of Cereal Science. 59, 3, p. 393-418 26 p.

Research output: Contribution to journal › Journal article › Research › peer-review

56 Citations (Scopus)

How insects overcome two-component plant chemical defence: plant β-glucosidases as the main target for herbivore adaptation

Pentzold, S., Zagrobelny, M., Rook, F. & Bak, S., Aug 2014, In: Biological Reviews. 89, 3, p. 531-551 21 p.

Research output: Contribution to journal › Review › peer-review

79 Citations (Scopus)

Sequestration, tissue distribution and developmental transmission of cyanogenic glucosides in a specialist insect herbivore

Zagrobelny, M., Olsen, C. E., Pentzold, S., Fürstenberg-Hägg, J., Jørgensen, K., Bak, S., Møller, B. L. & Motawie, M. S., Jan 2014, In: Insect Biochemistry and Molecular Biology. 44, p. 44-53 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

The multiple strategies of an insect herbivore to overcome plant cyanogenic glucoside defence

Pentzold, S., Zagrobelny, M., Roelsgaard, P. S., Møller, B. L. & Bak, S., 13 Mar 2014, In: PLOS ONE. 9, 3, 8 p., e91337.

Research output: Contribution to journal › Journal article › Research › peer-review

45 Citations (Scopus)

1527 Downloads (Pure)

Transcriptional regulation of de novo biosynthesis of cyanogenic glucosides throughout the life-cycle of the burnet moth Zyagena filipendulae (Lepidoptera)

Fürstenberg-Hägg, J., Zagrobelny, M., Olsen, C. E., Jørgensen, K., Møller, B. L. & Bak, S., Jun 2014, In: Insect Biochemistry and Molecular Biology. 49, p. 80-89 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

2013

Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants

Geisler, K., Hughes, R. K., Sainsbury, F., Lomonossoff, G. P., Rejzek, M., Fairhurst, S., Olsen, C. E., Motawie, M. S., Melton, R. E., Hemmings, A. M., Bak, S. & Osbourn, A., 27 Aug 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 35, p. E3360-E3367 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

96 Citations (Scopus)

Integrative analysis of metabolomics and transcriptomics data: a unified model framework to identify underlying system pathways

Brink-Jensen, K., Bak, S., Jørgensen, K. & Ekstrøm, C. T., 25 Sept 2013, In: P L o S One. 8, 9, 8 p., e72116.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

1683 Downloads (Pure)

Male-to-female transfer of 5-hydroxytryptophan glucoside during mating in Zyagena filipendulae (Lepidoptera)

Zagrobelny, M., Motawie, M. S., Olsen, C. E., Bak, S. & Møller, B. L., 2013, In: Insect Biochemistry and Molecular Biology. 43, 11, p. 1037-1044 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Plant defense against insect herbivores

Fürstenberg-Hägg, J., Zagrobelny, M. & Bak, S., May 2013, In: International Journal of Molecular Sciences (Online). 14, 5, 56 p.

Research output: Contribution to journal › Review › peer-review

342 Citations (Scopus)

4579 Downloads (Pure)

Plant P450s as versatile drivers for evolution of species-specific chemical diversity

Hamberger, B. R. & Bak, S., 19 Feb 2013, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 368, 1612, 16 p., 20120426.

Research output: Contribution to journal › Journal article › Research › peer-review

166 Citations (Scopus)

The use of trimethylsilyl cyanide derivatization for robust and broad-spectrum high-throughput gas chromatography–mass spectrometry based metabolomics

Khakimov, B., Motawie, M. S., Bak, S. & Engelsen, S. B., Nov 2013, In: Analytical and Bioanalytical Chemistry. 405, 28, p. 9193-9205 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

Visualizing metabolite distribution and enzymatic conversion in plant tissues by desorption electrospray ionization mass spectrometry imaging

Li, B., Baden, C. K., Hansen, N. K. K., Jørgensen, K., Kannangara, R. M., Bak, S., Takos, A. M., Rook, F., Hansen, S. H., Møller, B. L., Janfelt, C. & Bjarnholt, N., Jun 2013, In: Plant Journal. 74, 6, p. 1059-1071 74.

Research output: Contribution to journal › Journal article › Research › peer-review

53 Citations (Scopus)

2012

Biosynthesis of rhodiocyanosides in Lotus japonicus: Rhodiocyanoside A is synthesized from (Z)-2-methylbutanaloxime via 2-methyl-2-butenenitrile

Saito, S., Motawie, M. S., Olsen, C. E., Møller, B. L. & Bak, S., May 2012, In: Phytochemistry. 77, p. 260-267 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

Plant metabolomics: resolution and quantification of elusive peaks in liquid chromatography–mass spectrometry profiles of complex plant extracts using multi-way decomposition methods

Khakimov, B., Amigo Rubio, J. M., Bak, S. & Engelsen, S. B., 30 Nov 2012, In: Journal of Chromatography A. 1266, p. 84-94 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

37 Citations (Scopus)

6 Downloads (Pure)

UDP-glycosyltransferases from the UGT₇₃C subfamily in Barbarea vulgaris catalyse Sapogenin ₃-O-glucosylation in Saponin-mediated Insect resistance

Augustin, J. M., Drok, S., Shinoda, T., Sanmiya, K., Nielsen, J. K., Khakimov, B., Olsen, C. E., Hansen, E. H., Poulsen, V. K., Ekstrøm, C. T., Hauser, T. P. & Bak, S., Dec 2012, In: Plant Physiology. 160, 4, p. 1881-1895 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

84 Citations (Scopus)

2673 Downloads (Pure)

2011

Barbarea vulgaris linkage map and quantitative trait loci for saponins, glucosinolates, hairiness and resistance to the herbivore Phyllotreta nemorum

Poulsen, V. K., Nielsen, J. K., Augustin, J. M., Torp, A. M., Bak, S. & Andersen, S. B., Feb 2011, In: Phytochemistry. 72, 2-3, p. 188-198 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

42 Citations (Scopus)

Biosynthesis of the cyanogenic glucosides linamarin and lotaustralin in cassava: isolation, biochemical, characterization, and expression pattern of CYP71E7, the oxime-metabolizing cytochrome P450 enzyme

Jørgensen, K., Morant, A. V., Morant, M., Jensen, N. B., Olsen, C. E., Kannangara, R. M., Motawie, M. S., Møller, B. L. & Bak, S., Jan 2011, In: Plant Physiology. 155, 1, p. 282-292 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

59 Citations (Scopus)

Convergent evolution in biosynthesis of cyanogenic defence compounds in plants and insects

Jensen, N. B., Zagrobelny, M., Hjernø, K., Olsen, C. E., Hougton-Larsen, J., Borch-Jensen, J., Møller, B. L. & Bak, S., 2011, In: Nature Communications. 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

87 Citations (Scopus)

Cytochromes P450

Bak, S., Beisson, F., Bishop, G., Hamberger, B. R., Höfer, R., Paquette, S. & Werck-Reichhart, D., 2011, The arabidopsis book. American Society of Plant Biologists, 56 p.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Molecular activities, biosynthesis and evolution of triterpenoid saponins

Augustin, J. M., Poulsen, V. K., Andersen, S. B. & Bak, S., Apr 2011, In: Phytochemistry. 72, 6, p. 435-457 23 p.

Research output: Contribution to journal › Journal article › Research › peer-review

408 Citations (Scopus)

2010

454 pyrosequencing based transcriptome analysis of Zygaena filipendulae with focus on genes involved in biosynthesis of cyanogenic glucosides

Zagrobelny, M., Scheibye-Alsing, K., Jensen, N. B., Møller, B. L., Gorodkin, J. & Bak, S., 2010.

Research output: Contribution to conference › Poster › Research

454 pyrosequencing based transcriptome analysis of Zygaena filipendulae with focus on genes involved in biosynthesis of cyanogenic glucosides

Zagrobelny, M., Scheibye-Alsing, K., Jensen, N. B., Møller, B. L., Gorodkin, J. & Bak, S., 2010.

Research output: Contribution to conference › Poster › Research

Interactions between Barbarea vulgaris, flea beetles and white rust

Hauser, T. P., Andersen, S. B., Augustin, J. M., Bak, S., Poulsen, V. K. & Munk, L., 2010.

Research output: Contribution to conference › Poster › Research

Metabolomic, transcriptional, hormonal, and signaling cross-talk in Superroot2

Morant, M. D., Ekstrøm, C. T., Ulvskov, P., Kristensen, C., Rudemo, M. E., Olsen, C. E., Hansen, J., Jørgensen, K., Jørgensen, B., Møller, B. L. & Bak, S., Jan 2010, In: Molecular Plant. 3, 1, p. 192-211 20 p.

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

Planters naturlige forsvar mod forskellige samtidige skadevoldere

Hauser, T. P., Nielsen, J. K., Munk, L., Poulsen, V. K., Bak, S., van Mölken, T. & Andersen, S. B., 2010, Plantekongres 2010: sammendrag af indlæg: 12-14 januar i Herning Kongrescenter. Dansk Landbrugsrådgivning, p. 402-403 2 p.

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

**The role of saponins in the tripartite interaction between Barbarea vulgaris (Brassicaceae), flea beetles and white rust.**

van Mölken, M. A. R., Hauser, T. P., Andersen, S. B., Augustin, J. M., Bak, S., Poulsen, V. K., Munk, L. & Nielsen, J. K., 2010.

Research output: Contribution to conference › Poster › Research

Søren Bak

Research output

Search results