Maria Buur Nordskov Gabe

2020

Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system

Gabe, M. B. N., van der Velden, W. J. C., Gadgaard, S., Smit, F. X., Hartmann, B., Brauner-Osborne, H. & Rosenkilde, M. M., 1 Jun 2020, In: Basic & Clinical Pharmacology & Toxicology.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

2019

GLP-2 and GIP exert separate effects on bone turnover: A randomized, placebo-controlled, crossover study in healthy young men

Skov-Jeppesen, K., Svane, M. S., Martinussen, C., Gabe, M. B. N., Gasbjerg, L. S., Veedfald, S., Bojsen-Møller, K. N., Madsbad, S., Holst, J. J., Rosenkilde, M. M. & Hartmann, B., Aug 2019, In: Bone. 125, p. 178-185

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

Neuromedin U Does Not Act as a Decretin in Rats

Kuhre, R. E., Christiansen, C. B., Ghiasi, S. M., Gabe, M. B. N., Skat-Rørdam, P. A., Modvig, I. M., Mandrup-Poulsen, T., Albrechtsen, R., Rosenkilde, M. M., Hartmann, B., Albrechtsen, N. J. W. & Holst, J. J., 2019, In: Cell Metabolism. 29, 3, p. 719-726.e1-e5 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

15 Downloads (Pure)

Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice

Jepsen, S. L., Grunddal, K. V., Wewer Albrechtsen, N. J., Engelstoft, M. S., Gabe, M. B. N., Jensen, E. P., Ørskov, C., Poulsen, S. S., Rosenkilde, M. M., Pedersen, J., Gribble, F. M., Reimann, F., Deacon, C. F., Schwartz, T. W., Christ, A. D., Martin, R. E. & Holst, J. J., Dec 2019, In: A J P: Endocrinology and Metabolism (Online).

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Separate and Combined Glucometabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide 1 in Healthy Individuals

Gasbjerg, L. S., Helsted, M. M., Hartmann, B., Jensen, M. H., Gabe, M. B. N., Sparre-Ulrich, A. H., Veedfald, S., Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, M. B., Vilsbøll, T., Holst, J. J., Rosenkilde, M. M. & Knop, F. K., 2019, In: Diabetes. 68, 3, p. 906-917

Research output: Contribution to journal › Journal article › Research › peer-review

46 Citations (Scopus)

The natural GIP receptor mutation E345Q displays enhanced signalling and internaliation mimicking GIP receptor desensitisation: [Meeting Abstract}

Gabe, M. B. N., 2019, In: Diabetologia. 62, Supl. 1/SI, p. S231-S231 471.

Research output: Contribution to journal › Conference article › Research

2018

GIP(3-30)NH₂ is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study

Gasbjerg, L. S., Christensen, M. B., Hartmann, B., Lanng, A. R., Sparre-Ulrich, A. H., Gabe, M. B. N., Dela, F., Vilsbøll, T., Holst, J. J., Rosenkilde, M. M. & Knop, F. K., 1 Feb 2018, In: Diabetologia. 61, 2, p. 413-423

Research output: Contribution to journal › Journal article › Research › peer-review

45 Citations (Scopus)

Glucose-dependent insulinotropic polypeptide (GIP) receptor antagonists as anti-diabetic agents

Gasbjerg, L. S., Gabe, M. B. N., Hartmann, B., Christensen, M. B., Knop, F. K., Holst, J. J. & Rosenkilde, M. M., Feb 2018, In: Peptides. 100, p. 173-181

Research output: Contribution to journal › Journal article › Research › peer-review

37 Citations (Scopus)

Glucose-lowering effects and mechanisms of the bile acid-sequestering resin sevelamer

Brønden, A., Mikkelsen, K., Sonne, D. P., Hansen, M., Våben, C., Gabe, M. N., Rosenkilde, M., Tremaroli, V., Wu, H., Bäckhed, F., Rehfeld, J. F., Holst, J. J., Vilsbøll, T. & Knop, F. K., Jul 2018, In: Diabetes, Obesity and Metabolism. 20, 7, p. 1623-1631

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Human GIP(3-30)NH inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors

Gabe, M. B. N., Sparre-Ulrich, A. H., Pedersen, M. F., Gasbjerg, L. S., Inoue, A., Bräuner-Osborne, H., Hartmann, B. & Rosenkilde, M. M., Apr 2018, In: Biochemical Pharmacology. 150, p. 97-107 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

Insulin Secretion Depends on Intra-islet Glucagon Signaling

Svendsen, B., Larsen, O., Gabe, M. B. N., Christiansen, C. B., Rosenkilde, M. M., Drucker, D. J. & Holst, J. J., 2018, In: Cell Reports. 25, 5, p. 1127-1134.E2

Research output: Contribution to journal › Journal article › Research › peer-review

91 Citations (Scopus)

60 Downloads (Pure)

Oxyntomodulin: actions and role in diabetes

Holst, J. J., Albrechtsen, N. J. W., Gabe, M. B. N. & Rosenkilde, M. M., 2018, In: Peptides. 100, p. 48-53 6 p.

Research output: Contribution to journal › Review › peer-review

27 Citations (Scopus)

Separate effects of glucagon like peptide-2 (GLP-2) and glucose-dependent insulinotropic polypeptide (GIP) on bone remodelling

Skov-Jeppesen, K., Svane, M., Martinussen, C., Gabe, M., Gasbjerg, L., Madsbad, S., Holst, J., Rosenkilde, M. & Hartmann, B., 2018, In: Diabetologia. 61, S1, p. S245-S245 501.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

The impact of short chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon

Christiansen, C. B., Gabe, M. B. N., Svendsen, B., Dragsted, L. O., Rosenkilde, M. & Holst, J. J., Jul 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 315, 1, p. G53-G65 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

81 Citations (Scopus)

19 Downloads (Pure)

2017

Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R. & Bojsen-Moller, K. N. & 9 others, Idorn, T., Deacon, C. F., Knop, F. K., Rosenkilde, M. M., Hartmann, B., Feldt-Rasmussen, B., Mann, M., Madsbad, S. & Holst, J. J., 7 Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

119 Downloads (Pure)

GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release

Sparre-Ulrich, A. H., Gabe, M. N., Gasbjerg, L. S., Christiansen, C. B., Svendsen, B., Hartmann, B., Holst, J. J. & Rosenkilde, M. M., 1 May 2017, In: Biochemical Pharmacology. 131, p. 78-88

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

93 Downloads (Pure)

Maria Buur Nordskov Gabe

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